ZA796708B - Therapeutic agents - Google Patents

Therapeutic agents

Info

Publication number: ZA796708B
Authority: ZA; South Africa
Prior art keywords: therapeutic agents; therapeutic; agents
Prior art date: 1978-12-13

Application number

ZA00796708A

Other languages

English (en)

Inventor

P Cross

R Dickinson

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-13

Filing date

1979-12-11

Publication date

1981-08-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10501705&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA796708(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1979-12-11 Application filed by Pfizer filed Critical Pfizer

1981-08-26 Publication of ZA796708B publication Critical patent/ZA796708B/xx

Links

239000003814 drug Substances 0.000 title 1
229940124597 therapeutic agent Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA00796708A 1978-12-13 1979-12-11 Therapeutic agents ZA796708B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB7848367		1978-12-13

Publications (1)

Publication Number	Publication Date
ZA796708B true ZA796708B (en)	1981-08-26

Family

ID=10501705

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00796708A ZA796708B (en)	1978-12-13	1979-12-11	Therapeutic agents

Country Status (34)

Country	Link
US (2)	US4602016A (da)
JP (1)	JPS585197B2 (da)
KR (1)	KR830001243B1 (da)
AR (1)	AR227637A1 (da)
AT (1)	AT373879B (da)
AU (1)	AU517892B2 (da)
BE (1)	BE880584A (da)
CA (1)	CA1108137A (da)
CH (1)	CH644597A5 (da)
CS (1)	CS216517B2 (da)
DD (1)	DD147943A5 (da)
DE (1)	DE2950019A1 (da)
DK (1)	DK471479A (da)
EG (1)	EG14227A (da)
ES (1)	ES8101556A1 (da)
FI (1)	FI70888C (da)
FR (1)	FR2444031A1 (da)
GB (1)	GB2038821B (da)
GR (1)	GR73003B (da)
HU (1)	HU183016B (da)
IE (1)	IE49318B1 (da)
IL (1)	IL58917A (da)
IT (1)	IT1194900B (da)
LU (1)	LU81985A1 (da)
NL (1)	NL177749C (da)
NO (1)	NO153135C (da)
NZ (1)	NZ192360A (da)
PH (1)	PH15056A (da)
PL (1)	PL134005B1 (da)
PT (1)	PT70571A (da)
SE (1)	SE444937B (da)
SU (1)	SU878195A3 (da)
YU (1)	YU301879A (da)
ZA (1)	ZA796708B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4350696A (en) *	1980-03-08	1982-09-21	Pfizer Inc.	Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof
US4444775A (en) *	1981-06-22	1984-04-24	Ciba-Geigy Corporation	Substituted imidazo[1,5-A]pyridines
DE3148291A1 (de) *	1981-12-05	1983-06-09	Basf Ag, 6700 Ludwigshafen	Harnstoffderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
JPS58113178A (ja) *	1981-12-28	1983-07-05	Yamanouchi Pharmaceut Co Ltd	「お」−（１−イミダゾリル）アルキルオキシ（またはチオ）ベンゼン誘導体
US4588732A (en) *	1982-12-21	1986-05-13	Ciba-Geigy Corporation	Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors
US4470986A (en) *	1982-12-21	1984-09-11	Ciba-Geigy Corporation	Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
NL8301550A (nl) *	1983-05-03	1984-12-03	Gist Brocades Nv	Imidazolethanol esters.
US4511573A (en) *	1983-05-17	1985-04-16	Ciba-Geigy Corporation	3-Substituted-2-(heteroaryl) indoles
PH22076A (en) *	1983-08-25	1988-05-20	Daiichi Seiyaku Co	Benzocycloalkane derivative
IT1212791B (it) *	1983-11-24	1989-11-30	Medea Res Srl	Derivato imidazolico adattivita' vasodilatatrice ed antitrombotica, sua preparazione e composizioni farmaceutiche che lo contengono.
ES8601148A1 (es) *	1984-12-10	1985-11-16	Ferrer Int	Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos.
JPH0625141B2 (ja) *	1985-01-16	1994-04-06	三共株式会社	イミダゾ−ル誘導体およびその製法
NO166644C (no)	1986-01-28	1991-08-21	Sankyo Co	Analogifremgangsmaate til fremstilling av tianaftenderivater.
ATE90076T1 (de)	1986-03-27	1993-06-15	Merck Frosst Canada Inc	Tetrahydrocarbazole ester.
JPS63179840A (ja) *	1986-07-24	1988-07-23	Yamanouchi Pharmaceut Co Ltd	新規化学物質
DE3860908D1 (de) *	1987-04-03	1990-12-06	Cl Pharma	Neue 2-thienyloxyessigsaeurederivate, ein verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
JPH01125372A (ja) *	1988-09-12	1989-05-17	Yamanouchi Pharmaceut Co Ltd	イミダゾリルアルキルオキシベンゼン誘導体
DE4204686A1 (de) *	1992-02-17	1993-08-19	Gruenenthal Gmbh	Imidazolylphenolderivate, diese enthaltende arzneimittel sowie ein verfahren zur herstellung dieser verbindungen und arzneimitteln
ES2201104T3 (es) *	1994-04-26	2004-03-16	Roche Palo Alto Llc	Derivados de benzociclohexilimidazoltiona.
AU2890899A (en) *	1998-03-13	1999-09-27	Pozen, Inc.	Prophylaxis and treatment of migraine headaches with thromboxane synthetase inhibitors and/or receptor antagonists
ES2172436B1 (es)	2000-10-31	2004-01-16	Almirall Prodesfarma Sa	Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
JP2005533830A (ja) *	2002-07-09	2005-11-10	ビー．エム．アール．エイ．コーポレイションベスローテンフェンノートシャップ	トロンボキサンａ２受容体アンタゴニストおよびｃｏｘ−２阻害剤の薬剤の組み合わせ
JP2007508242A (ja) *	2003-08-07	2007-04-05	ビー．エム．アール．エイ．コーポレイションベスローテンフェンノートシャップ	トロンボキサンａ２受容体アンタゴニストとシクロオキシゲネーゼ−１の阻害剤との組み合わせを伴う組成物および方法
KR101275814B1 (ko) *	2006-06-23	2013-06-18	삼성에스디아이 주식회사	분산제 화합물 및 그의 제조방법
EP2234608A2 (en)	2007-12-11	2010-10-06	Viamet Pharmaceuticals, Inc.	Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
CN101811974B (zh) *	2010-04-15	2012-12-12	合肥医工医药有限公司	4-(3-(二甲氨基)丙氧基)-3,5-二甲氧基苯甲酸、其制法及医药用途
CN101851209B (zh) *	2010-06-21	2012-09-19	合肥医工医药有限公司	咪唑乙基香草酸醚、其制备方法及其医药用途
CA2874621A1 (en) *	2012-05-22	2013-11-28	Genentech, Inc.	N-substituted benzamides and their use in the treatment of pain
AU2013334664A1 (en)	2012-10-26	2015-05-07	Merck Sharp & Dohme Corp.	N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels
WO2023240378A1 (zh) *	2022-06-13	2023-12-21	南京医工医药技术有限公司	咪唑烷基香草酸醚衍生物及其用途
CN114736161B (zh) *	2022-06-13	2022-09-13	南京医工医药技术有限公司	咪唑烷基香草酸醚衍生物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3534061A (en) *	1967-12-04	1970-10-13	Parke Davis & Co	N-(alpha-(p-methoxyphenyl)-beta-nitrostyryl)-phenoxyalkyl pyrroles
US4085209A (en) *	1975-02-05	1978-04-18	Rohm And Haas Company	Preparation and safening effect of 1-substituted imidazole metal salt complexes
US4078071A (en) *	1976-03-08	1978-03-07	Syntex (U.S.A.) Inc.	Derivatives of substituted N-alkyl imidazoles
JPS5951943B2 (ja) *	1978-08-21	1984-12-17	キツセイ薬品工業株式会社	新規なイミダゾ−ル誘導体

1979
- 1979-11-07 DK DK471479A patent/DK471479A/da not_active Application Discontinuation
- 1979-11-19 US US06/095,755 patent/US4602016A/en not_active Expired - Lifetime
- 1979-12-10 GB GB7942535A patent/GB2038821B/en not_active Expired
- 1979-12-10 AR AR279215A patent/AR227637A1/es active
- 1979-12-11 NL NLAANVRAGE7908899,A patent/NL177749C/xx not_active IP Right Cessation
- 1979-12-11 ES ES486782A patent/ES8101556A1/es not_active Expired
- 1979-12-11 PT PT70571A patent/PT70571A/pt unknown
- 1979-12-11 YU YU03018/79A patent/YU301879A/xx unknown
- 1979-12-11 IL IL58917A patent/IL58917A/xx unknown
- 1979-12-11 IT IT41669/79A patent/IT1194900B/it active
- 1979-12-11 ZA ZA00796708A patent/ZA796708B/xx unknown
- 1979-12-11 NZ NZ192360A patent/NZ192360A/xx unknown
- 1979-12-11 GR GR60727A patent/GR73003B/el unknown
- 1979-12-11 HU HU79PI699A patent/HU183016B/hu unknown
- 1979-12-11 FI FI793868A patent/FI70888C/fi not_active IP Right Cessation
- 1979-12-11 SE SE7910204A patent/SE444937B/sv unknown
- 1979-12-12 LU LU81985A patent/LU81985A1/fr unknown
- 1979-12-12 CS CS798708A patent/CS216517B2/cs unknown
- 1979-12-12 IE IE2403/79A patent/IE49318B1/en unknown
- 1979-12-12 JP JP54161382A patent/JPS585197B2/ja not_active Expired
- 1979-12-12 NO NO794069A patent/NO153135C/no unknown
- 1979-12-12 PL PL1979220351A patent/PL134005B1/pl unknown
- 1979-12-12 AT AT0783379A patent/AT373879B/de not_active IP Right Cessation
- 1979-12-12 AU AU53725/79A patent/AU517892B2/en not_active Ceased
- 1979-12-12 FR FR7930438A patent/FR2444031A1/fr active Granted
- 1979-12-12 DE DE19792950019 patent/DE2950019A1/de not_active Ceased
- 1979-12-12 SU SU792854456A patent/SU878195A3/ru active
- 1979-12-12 EG EG743/79A patent/EG14227A/xx active
- 1979-12-12 BE BE0/198542A patent/BE880584A/fr not_active IP Right Cessation
- 1979-12-12 CA CA341,691A patent/CA1108137A/en not_active Expired
- 1979-12-12 KR KR1019790004397A patent/KR830001243B1/ko not_active Expired
- 1979-12-13 PH PH23412A patent/PH15056A/en unknown
- 1979-12-13 DD DD79217645A patent/DD147943A5/de unknown
- 1979-12-13 CH CH1106279A patent/CH644597A5/de not_active IP Right Cessation
1985
- 1985-03-21 US US06/714,422 patent/US4636500A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR830001242A (ko)	1983-04-29
HU183016B (en)	1984-04-28
IT1194900B (it)	1988-09-28
IT7941669A0 (it)	1979-12-11
PH15056A (en)	1982-06-03
NO153135C (no)	1986-01-22
LU81985A1 (fr)	1980-04-22
DK471479A (da)	1980-06-14
FI70888B (fi)	1986-07-18
PL134005B1 (en)	1985-07-31
SU878195A3 (ru)	1981-10-30
NO794069L (no)	1980-06-16
FI793868A7 (fi)	1980-06-14
CH644597A5 (de)	1984-08-15
NL177749B (nl)	1985-06-17
CS216517B2 (en)	1982-11-26
JPS585197B2 (ja)	1983-01-29
KR830001243B1 (ko)	1983-06-27
AR227637A1 (es)	1982-11-30
CA1108137A (en)	1981-09-01
PL220351A1 (da)	1980-12-01
JPS5585572A (en)	1980-06-27
GR73003B (da)	1984-01-24
IE49318B1 (en)	1985-09-18
AU5372579A (en)	1980-06-19
DD147943A5 (de)	1981-04-29
ATA783379A (de)	1983-07-15
SE7910204L (sv)	1980-06-14
NL177749C (nl)	1985-11-18
DE2950019A1 (de)	1980-07-10
IL58917A0 (en)	1980-03-31
NO153135B (no)	1985-10-14
ES486782A0 (es)	1980-12-16
AT373879B (de)	1984-02-27
EG14227A (en)	1983-12-31
US4602016A (en)	1986-07-22
FR2444031A1 (fr)	1980-07-11
NL7908899A (nl)	1980-06-17
ES8101556A1 (es)	1980-12-16
SE444937B (sv)	1986-05-20
PT70571A (en)	1980-01-01
FR2444031B1 (da)	1983-06-10
GB2038821B (en)	1982-12-08
GB2038821A (en)	1980-07-30
YU301879A (en)	1983-01-21
US4636500A (en)	1987-01-13
NZ192360A (en)	1982-02-23
AU517892B2 (en)	1981-09-03
BE880584A (fr)	1980-06-12
FI70888C (fi)	1986-10-27
IE792403L (en)	1980-06-13
IL58917A (en)	1984-03-30

Publication	Publication Date	Title
PH15198A (en)	1982-09-17	Therapeutic agents
GB2000136B (en)	1982-01-06	Therapeutic agents
GB2005248B (en)	1982-03-24	Therapeutic agents
GB2000138B (en)	1982-03-03	Therapeutic agents
ZA80298B (en)	1981-08-26	Therapeutic agents
GB2000131B (en)	1982-01-13	Therapeutic agents
EG16606A (en)	1989-01-30	Therapeutic agents
ZA792390B (en)	1980-07-30	Therapeutic agents
GB2013181B (en)	1982-06-03	Therapeutic agents
GB2004876B (en)	1982-03-10	Therapeutic agents
ZA796959B (en)	1981-03-25	5-aryl-4-isoxazolecarboxylate-safening agents
GB2019836B (en)	1982-06-03	Therapeutic agents
GB2007656B (en)	1982-05-19	Therapeutic agents
GB2011890B (en)	1982-05-26	Therapeutic agents
GB2000510B (en)	1982-01-27	Therapeutic agents
GB2053910B (en)	1983-04-20	Pyridylaminotriazole therapeutic agents
GB2047691B (en)	1983-07-20	Therapeutic agents
GB2011891B (en)	1982-05-26	Therapeutic agents
GB2013179B (en)	1982-06-03	Therapeutic agents
GB2010824B (en)	1982-06-16	Therapeutic agents
GB2008104B (en)	1982-03-10	Therapeutic agents
GB2007654B (en)	1982-06-16	Therapeutic agents
GB2000441B (en)	1982-01-06	Therapeutic agents
GB2009156B (en)	1982-05-12	Therapeutic agents
JPS54158091A (en)	1979-12-13	Massager