EG22344A - Process for preparing of novel pharmaceutical composition - Google Patents

Process for preparing of novel pharmaceutical composition

Info

Publication number: EG22344A
Authority: EG; Egypt
Prior art keywords: preparing; pharmaceutical composition; novel pharmaceutical; novel; composition
Prior art date: 1998-11-12

Application number

EG142899A

Other languages

English (en)

Inventor

Robert Glinecke

Original Assignee

Smithkline Beecham Plc

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-12

Filing date

1999-11-11

Publication date

2002-12-31

1998-11-12 Priority claimed from GBGB9824870.1A external-priority patent/GB9824870D0/en

1999-05-25 Priority claimed from GBGB9912189.9A external-priority patent/GB9912189D0/en

1999-11-11 Application filed by Smithkline Beecham Plc, Smithkline Beecham Corp filed Critical Smithkline Beecham Plc

2002-12-31 Application granted granted Critical

2002-12-31 Publication of EG22344A publication Critical patent/EG22344A/xx

Links

238000004519 manufacturing process Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Thiazole And Isothizaole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

EG142899A 1998-11-12 1999-11-11 Process for preparing of novel pharmaceutical composition EG22344A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9824870.1A GB9824870D0 (en)	1998-11-12	1998-11-12	Novel composition and use
GBGB9912189.9A GB9912189D0 (en)	1999-05-25	1999-05-25	Novel composition and use

Publications (1)

Publication Number	Publication Date
EG22344A true EG22344A (en)	2002-12-31

Family

ID=26314667

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
EG142899A EG22344A (en)	1998-11-12	1999-11-11	Process for preparing of novel pharmaceutical composition
EG142999A EG24463A (en)	1998-11-12	1999-11-11	Modified release pharmaceutical composition

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
EG142999A EG24463A (en)	1998-11-12	1999-11-11	Modified release pharmaceutical composition

Country Status (39)

Country	Link
EP (3)	EP1815855A1 (fr)
JP (1)	JP2002529505A (fr)
KR (2)	KR20060097140A (fr)
CN (1)	CN1289081C (fr)
AP (2)	AP2008004490A0 (fr)
AR (2)	AR023700A1 (fr)
AT (1)	ATE382352T1 (fr)
AU (1)	AU768578B2 (fr)
BG (2)	BG109893A (fr)
BR (1)	BR9915215A (fr)
CA (1)	CA2350659C (fr)
CO (1)	CO5190673A1 (fr)
CY (1)	CY1107909T1 (fr)
CZ (1)	CZ20011628A3 (fr)
DE (1)	DE69937898T2 (fr)
DK (1)	DK1128827T3 (fr)
DZ (1)	DZ2937A1 (fr)
EA (3)	EA200601144A1 (fr)
EG (2)	EG22344A (fr)
ES (1)	ES2299269T3 (fr)
HK (1)	HK1040909B (fr)
HR (2)	HRP20080117A2 (fr)
HU (1)	HUP0104307A3 (fr)
ID (1)	ID29344A (fr)
IL (2)	IL143003A0 (fr)
MY (1)	MY135973A (fr)
NO (1)	NO20012351L (fr)
NZ (2)	NZ511611A (fr)
OA (1)	OA11676A (fr)
PE (1)	PE20001428A1 (fr)
PL (1)	PL198717B1 (fr)
PT (1)	PT1128827E (fr)
RS (1)	RS50208B (fr)
SI (1)	SI1128827T1 (fr)
SK (1)	SK286937B6 (fr)
TR (2)	TR200503846T2 (fr)
TW (2)	TWI246920B (fr)
UY (2)	UY25798A1 (fr)
WO (1)	WO2000028990A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6099862A (en) *	1998-08-31	2000-08-08	Andrx Corporation	Oral dosage form for the controlled release of a biguanide and sulfonylurea
AR030920A1 (es)	1999-11-16	2003-09-03	Smithkline Beecham Plc	Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones
AU783099B2 (en) *	2000-01-07	2005-09-22	Rohm Gmbh & Co. Kg	Selective activation of a TH1 or TH2 lymphocyte regulated immune response
SK287902B6 (sk) *	2001-01-31	2012-03-02	Evonik Rohm Gmbh	Multiparticulate drug form and method for the preparation thereof
US20050107450A1 (en) *	2001-12-21	2005-05-19	Brown Kathleen K.	Dosing regimen for ppar-gamma activators
MY139719A (en) *	2002-02-12	2009-10-30	Glaxo Group Ltd	Oral dosage form for controlled drug release
WO2004006921A1 (fr) *	2002-07-11	2004-01-22	Takeda Pharmaceutical Company Limited	Procede de production d'une preparation recouverte
US7018658B2 (en) *	2002-11-14	2006-03-28	Synthon Bv	Pharmaceutical pellets comprising tamsulosin
EP1589951B1 (fr) *	2003-01-03	2017-08-09	Supernus Pharmaceuticals, Inc.	Utilisation d'un melange de deux ou de plusieurs materiaux enteriques afin de reguler la liberation de medicaments via une membrane ou une matrice dans des therapies systemiques
US7976853B2 (en)	2003-01-29	2011-07-12	Takeda Pharmaceutical Company Limited	Process for producing coated preparation
ES2241478B1 (es) *	2004-02-13	2006-11-16	Lacer S.A.	Preparacion farmaceutica para la liberacion sostenida de un principio farmaceuticamente activo.
FI20060501A7 (fi) *	2006-05-22	2007-11-23	Biohit Oyj	Koostumus ja menetelmä asetaldehydin sitomiseksi mahalaukussa
EP2731593A4 (fr) *	2011-07-14	2015-07-01	Able Cerebral Llc	Composition, dispositif et procédé pour la libération retardée et prolongée de molécules énergéniques pour le cerveau
CA2936741C (fr)	2014-10-31	2018-11-06	Purdue Pharma	Methodes et compositions destinees au traitement du trouble de deficit d'attention
US10722473B2 (en)	2018-11-19	2020-07-28	Purdue Pharma L.P.	Methods and compositions particularly for treatment of attention deficit disorder

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JPS5697277A (en)	1980-01-07	1981-08-05	Takeda Chem Ind Ltd	Thiazolidine derivative
JPS6051189A (ja)	1983-08-30	1985-03-22	Sankyo Co Ltd	チアゾリジン誘導体およびその製造法
US4582839A (en)	1984-03-21	1986-04-15	Takeda Chemical Industries, Ltd.	2,4-thiazolidinediones
CN1003445B (zh)	1984-10-03	1989-03-01	武田药品工业株式会社	噻唑烷二酮衍生物，其制备方法和用途
DK173350B1 (da)	1985-02-26	2000-08-07	Sankyo Co	Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
JPH06779B2 (ja)	1985-06-10	1994-01-05	武田薬品工業株式会社	チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en)	1986-07-24	1989-03-14	Takeda Chemical Industries, Ltd.	Method for producing thiazolidinedione derivatives
ATE186724T1 (de) *	1987-09-04	1999-12-15	Beecham Group Plc	Substituierte thiazolidindionderivate
US4791125A (en)	1987-12-02	1988-12-13	Pfizer Inc.	Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008650A1 (fr)	1988-03-08	1989-09-21	Pfizer Inc.	Agents hypoglycemiques de thiazolidinedione
MX15171A (es)	1988-03-08	1993-05-01	Pfizer	Derivados de tiazolidinodiona hipoglicemicos
WO1991007107A1 (fr)	1989-11-13	1991-05-30	Pfizer Inc.	Agents d'oxazolidinedione hypoglycemiques
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HUT65619A (en)	1990-07-03	1994-07-28	Yamanouchi Pharma Co Ltd	Process for producing bisheterocyclic compounds and pharmaceutical preparations containing them
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JPH04210683A (ja)	1990-12-06	1992-07-31	Terumo Corp	チアゾリジン−２，４−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
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US5264451A (en)	1992-04-07	1993-11-23	American Home Products Corporation	Process for treating hyperglycemia using trifluoromethyl substituted 3H-pyrazol-3-ones
AU3959193A (en)	1992-04-10	1993-11-18	Smithkline Beecham Plc	Heterocyclic compounds and their use in the treatment of type II-diabetes
WO1993022445A1 (fr)	1992-05-05	1993-11-11	The Upjohn Company	Procede de production de metabolites de pioglitazone
NZ253742A (en)	1992-07-03	1997-06-24	Smithkline Beecham Plc	Heterocyclylaminoalkoxy substituted phenyl derivatives and pharmaceutical compositions
US5326770A (en) *	1992-07-17	1994-07-05	The Du Pont Merck Pharmaceutical Company	Monoamine oxidase-B (MAO-B) inhibitory 5-substituted 2,4-thiazolidinediones useful in treating memory disorders of mammals
US5232945A (en)	1992-07-20	1993-08-03	Pfizer Inc.	3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5478852C1 (en)	1993-09-15	2001-03-13	Sankyo Co	Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
DE4432757A1 (de) *	1994-09-14	1996-03-21	Boehringer Mannheim Gmbh	Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
TW438587B (en) *	1995-06-20	2001-06-07	Takeda Chemical Industries Ltd	A pharmaceutical composition for prophylaxis and treatment of diabetes
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JP3256841B2 (ja) *	1996-06-27	2002-02-18	武田薬品工業株式会社	ベンズアルデヒド化合物の製造法
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GB9619757D0 (en) *	1996-09-21	1996-11-06	Knoll Ag	Chemical process
IL132032A0 (en) *	1997-03-24	2001-03-19	Galderma Res & Dev	Retinoid related molecules for the treatment of non-insulin dependent diabetes mellitus

1999
- 1999-11-10 AR ARP990105699A patent/AR023700A1/es unknown
- 1999-11-10 AR ARP990105698A patent/AR023699A1/es unknown
- 1999-11-10 DZ DZ990237A patent/DZ2937A1/fr active
- 1999-11-11 CO CO99070989A patent/CO5190673A1/es not_active Application Discontinuation
- 1999-11-11 MY MYPI99004894A patent/MY135973A/en unknown
- 1999-11-11 EG EG142899A patent/EG22344A/xx active
- 1999-11-11 EG EG142999A patent/EG24463A/xx active
- 1999-11-12 JP JP2000582037A patent/JP2002529505A/ja active Pending
- 1999-11-12 SK SK643-2001A patent/SK286937B6/sk not_active IP Right Cessation
- 1999-11-12 ID IDW00200101047A patent/ID29344A/id unknown
- 1999-11-12 HR HR20080117A patent/HRP20080117A2/xx not_active Application Discontinuation
- 1999-11-12 KR KR1020067017464A patent/KR20060097140A/ko not_active Ceased
- 1999-11-12 EP EP07105991A patent/EP1815855A1/fr not_active Withdrawn
- 1999-11-12 HU HU0104307A patent/HUP0104307A3/hu unknown
- 1999-11-12 CN CNB998154946A patent/CN1289081C/zh not_active Expired - Fee Related
- 1999-11-12 HR HR20010342A patent/HRP20010342B1/xx not_active IP Right Cessation
- 1999-11-12 AP AP2008004490A patent/AP2008004490A0/xx unknown
- 1999-11-12 AT AT99956029T patent/ATE382352T1/de not_active IP Right Cessation
- 1999-11-12 PT PT99956029T patent/PT1128827E/pt unknown
- 1999-11-12 PE PE1999001147A patent/PE20001428A1/es not_active Application Discontinuation
- 1999-11-12 EP EP99956029A patent/EP1128827B1/fr not_active Expired - Lifetime
- 1999-11-12 ES ES99956029T patent/ES2299269T3/es not_active Expired - Lifetime
- 1999-11-12 UY UY25798A patent/UY25798A1/es not_active Application Discontinuation
- 1999-11-12 EP EP07150269A patent/EP1917962A1/fr not_active Withdrawn
- 1999-11-12 OA OA1200100116A patent/OA11676A/en unknown
- 1999-11-12 PL PL348153A patent/PL198717B1/pl not_active IP Right Cessation
- 1999-11-12 WO PCT/EP1999/009031 patent/WO2000028990A1/fr not_active Ceased
- 1999-11-12 AP APAP/P/2001/002135A patent/AP1901A/en active
- 1999-11-12 NZ NZ511611A patent/NZ511611A/en not_active IP Right Cessation
- 1999-11-12 EA EA200601144A patent/EA200601144A1/ru unknown
- 1999-11-12 EA EA200702648A patent/EA200702648A1/ru unknown
- 1999-11-12 TR TR2005/03846T patent/TR200503846T2/xx unknown
- 1999-11-12 NZ NZ526440A patent/NZ526440A/en not_active IP Right Cessation
- 1999-11-12 SI SI9931001T patent/SI1128827T1/sl unknown
- 1999-11-12 DK DK99956029T patent/DK1128827T3/da active
- 1999-11-12 CZ CZ20011628A patent/CZ20011628A3/cs unknown
- 1999-11-12 KR KR1020017005949A patent/KR100732599B1/ko not_active Expired - Fee Related
- 1999-11-12 RS YU36401A patent/RS50208B/sr unknown
- 1999-11-12 TR TR2001/01337T patent/TR200101337T2/xx unknown
- 1999-11-12 CA CA002350659A patent/CA2350659C/fr not_active Expired - Fee Related
- 1999-11-12 BR BR9915215-0A patent/BR9915215A/pt not_active Application Discontinuation
- 1999-11-12 HK HK02101021.9A patent/HK1040909B/en not_active IP Right Cessation
- 1999-11-12 IL IL14300399A patent/IL143003A0/xx unknown
- 1999-11-12 DE DE69937898T patent/DE69937898T2/de not_active Expired - Lifetime
- 1999-11-12 EA EA200100540A patent/EA007608B1/ru not_active IP Right Cessation
- 1999-11-12 AU AU12729/00A patent/AU768578B2/en not_active Ceased
- 1999-11-15 UY UY25800A patent/UY25800A1/es not_active Application Discontinuation
- 1999-12-24 TW TW088122852A patent/TWI246920B/zh not_active IP Right Cessation
- 1999-12-24 TW TW093132308A patent/TWI257305B/zh active
2001
- 2001-05-11 NO NO20012351A patent/NO20012351L/no not_active Application Discontinuation
- 2001-06-07 BG BG109893A patent/BG109893A/bg unknown
- 2001-06-07 BG BG105570A patent/BG65444B1/bg unknown
2007
- 2007-06-14 IL IL183972A patent/IL183972A0/en unknown
2008
- 2008-03-19 CY CY20081100310T patent/CY1107909T1/el unknown

Also Published As

Publication number	Publication date
SK6432001A3 (en)	2001-12-03
WO2000028990A1 (fr)	2000-05-25
TWI246920B (en)	2006-01-11
PT1128827E (pt)	2008-03-10
SI1128827T1 (sl)	2008-06-30
AU768578B2 (en)	2003-12-18
PE20001428A1 (es)	2001-02-08
TR200101337T2 (tr)	2001-11-21
DE69937898T2 (de)	2009-01-02
DZ2937A1 (fr)	2004-03-15
HRP20080117A2 (en)	2008-10-31
ID29344A (id)	2001-08-23
DE69937898D1 (de)	2008-02-14
NZ526440A (en)	2005-01-28
ATE382352T1 (de)	2008-01-15
HRP20010342A2 (en)	2002-06-30
NZ511611A (en)	2003-10-31
CY1107909T1 (el)	2013-09-04
UY25800A1 (es)	2000-08-21
CA2350659A1 (fr)	2000-05-25
KR100732599B1 (ko)	2007-06-27
OA11676A (en)	2005-01-12
PL348153A1 (en)	2002-05-06
BG105570A (en)	2002-02-28
HUP0104307A3 (en)	2003-12-29
BG109893A (bg)	2008-11-28
KR20010073229A (ko)	2001-07-31
UY25798A1 (es)	2000-12-29
TR200503846T2 (tr)	2007-01-22
AU1272900A (en)	2000-06-05
KR20060097140A (ko)	2006-09-13
RS50208B (sr)	2009-07-15
EP1815855A1 (fr)	2007-08-08
BG65444B1 (bg)	2008-08-29
AR023699A1 (es)	2002-09-04
AP1901A (en)	2008-10-24
TWI257305B (en)	2006-07-01
NO20012351L (no)	2001-07-04
JP2002529505A (ja)	2002-09-10
EP1917962A1 (fr)	2008-05-07
BR9915215A (pt)	2001-07-31
CN1289081C (zh)	2006-12-13
EP1128827A1 (fr)	2001-09-05
ES2299269T3 (es)	2008-05-16
TW200505436A (en)	2005-02-16
EA200601144A1 (ru)	2007-02-27
IL183972A0 (en)	2007-10-31
EA200100540A1 (ru)	2001-10-22
HK1040909A1 (en)	2002-06-28
EP1128827B1 (fr)	2008-01-02
CN1333683A (zh)	2002-01-30
AP2008004490A0 (en)	2008-06-30
YU36401A (sh)	2004-05-12
CA2350659C (fr)	2009-06-09
MY135973A (en)	2008-07-31
EA007608B1 (ru)	2006-12-29
CO5190673A1 (es)	2002-08-29
AR023700A1 (es)	2002-09-04
HK1040909B (en)	2008-08-01
EA200702648A1 (ru)	2008-10-30
HRP20010342B1 (en)	2008-04-30
IL143003A0 (en)	2002-04-21
CZ20011628A3 (cs)	2001-12-12
EG24463A (en)	2009-07-16
PL198717B1 (pl)	2008-07-31
DK1128827T3 (da)	2008-04-28
NO20012351D0 (no)	2001-05-11
SK286937B6 (sk)	2009-07-06
HUP0104307A2 (hu)	2002-07-29

Publication	Publication Date	Title
HUP0003844A3 (en)	2002-11-28	Novel spiroazabicyclic heterocyclic compounds, process for their preparation, their use and pharmaceutical compositions containing them
HUP0103511A3 (en)	2002-07-29	Oxazole compounds and pharmaceutical compositions containing them and process for preparation the compounds
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HUP0203257A3 (en)	2003-05-28	Polymorphic forms of atorvastatin calcium, process for their preparations and pharmaceutical compositions containing them
HUP0203107A3 (en)	2004-06-28	Novel spiro compounds, process for their preparation and pharmaceutical compositions containing them
HUP0100731A3 (en)	2002-08-28	New oxazolidine-, thiazolidine-, pyrrolidine-and piperidin derivatives process for their preparation and pharmaceutical compositions containing them
HUP9900120A3 (en)	2001-02-28	Benzosulfone derivatives, process for producing them and pharmaceutical compositions containing them
HUP0105108A3 (en)	2002-11-28	Amide compounds, process for their preparation and pharmaceutical compositions containing them
EG22337A (en)	2002-12-31	Process for preparing novel pharmaceutical compounds
HUP0003053A3 (en)	2003-03-28	Crystalline forms of 33-epichloro-33-desoxyascomycin, process for their preparation and pharmaceutical compositions containing them
HU9802180D0 (en)	1998-11-30	Process for producing pharmaceutical compositions
IL129906A0 (en)	2000-02-29	Process for the preparation of beta-isophorone
HUP0001093A3 (en)	2001-07-30	Oxazolidines as 5-ht2a-antagonists, pharmaceutical compositions containing the same and process for their preparation
IL133140A0 (en)	2001-03-19	Novel process for the preparation of 4-aryl-piperidines
HUP0000572A3 (en)	2002-10-28	Pharmaceutical compositions containing nucleotide analogs and process for preparing them
HUP9701921A3 (en)	1999-03-29	Heterocyclic amino-methyl compounds, process for producing them, and pharmaceutical compositions containing them
HUP0204005A3 (en)	2003-05-28	Novel forms of pravastatin sodium, process for their preparation and pharmaceutical compositions containing them
HUP0004663A3 (en)	2002-10-28	Substituted isoquinoline derivatives, process for producing them and use of them for producing pharmaceutical compositions as anticonvulsants and pharmaceutical compositions containing them
HUP0202379A3 (en)	2003-04-28	New compounds, process for producing them and pharmaceutical compositions containing them
IL131205A0 (en)	2001-01-28	Process for preparing pharmaceutical compounds
HUP0003766A3 (en)	2001-09-28	Isoguinolin derivatives, process for producing them and pharmaceutical compositions containing them
HUP0003997A3 (en)	2001-04-28	3-benzylpiperidine derivatives, pharmaceutical compositions containing them and process for producing them
HUP0100019A3 (en)	2003-01-28	Novel polymorphic forms of cipamfylline, process for their preparation and pharmaceutical compositions thereof
HUP0003962A3 (en)	2001-12-28	Quinuclidinium compounds process for preparing thereof, pharmaceutical compositions comprising thereof, their use, and their intermediates
HUP0104202A3 (en)	2003-12-29	Thiazole-derivatives, process for their preparation and pharmaceutical compositions containing them