IL143003A0 - Pharmaceutical composition for modified release insulin sensitiser - Google Patents

Pharmaceutical composition for modified release insulin sensitiser

Info

Publication number
IL143003A0
IL143003A0 IL14300399A IL14300399A IL143003A0 IL 143003 A0 IL143003 A0 IL 143003A0 IL 14300399 A IL14300399 A IL 14300399A IL 14300399 A IL14300399 A IL 14300399A IL 143003 A0 IL143003 A0 IL 143003A0
Authority
IL
Israel
Prior art keywords
pharmaceutical composition
modified release
release insulin
insulin sensitiser
sensitiser
Prior art date
Application number
IL14300399A
Other languages
English (en)
Original Assignee
Smithkline Beecham Corp
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9824870.1A external-priority patent/GB9824870D0/en
Priority claimed from GBGB9912189.9A external-priority patent/GB9912189D0/en
Application filed by Smithkline Beecham Corp, Smithkline Beecham Plc filed Critical Smithkline Beecham Corp
Publication of IL143003A0 publication Critical patent/IL143003A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14300399A 1998-11-12 1999-11-12 Pharmaceutical composition for modified release insulin sensitiser IL143003A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9824870.1A GB9824870D0 (en) 1998-11-12 1998-11-12 Novel composition and use
GBGB9912189.9A GB9912189D0 (en) 1999-05-25 1999-05-25 Novel composition and use
PCT/EP1999/009031 WO2000028990A1 (fr) 1998-11-12 1999-11-12 Composition pharmaceutique de sensibilisateur modifiant la liberation d'insuline

Publications (1)

Publication Number Publication Date
IL143003A0 true IL143003A0 (en) 2002-04-21

Family

ID=26314667

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14300399A IL143003A0 (en) 1998-11-12 1999-11-12 Pharmaceutical composition for modified release insulin sensitiser
IL183972A IL183972A0 (en) 1998-11-12 2007-06-14 Pharmaceutical composition for modified release insulin sensitiser

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL183972A IL183972A0 (en) 1998-11-12 2007-06-14 Pharmaceutical composition for modified release insulin sensitiser

Country Status (39)

Country Link
EP (3) EP1128827B1 (fr)
JP (1) JP2002529505A (fr)
KR (2) KR20060097140A (fr)
CN (1) CN1289081C (fr)
AP (2) AP2008004490A0 (fr)
AR (2) AR023700A1 (fr)
AT (1) ATE382352T1 (fr)
AU (1) AU768578B2 (fr)
BG (2) BG65444B1 (fr)
BR (1) BR9915215A (fr)
CA (1) CA2350659C (fr)
CO (1) CO5190673A1 (fr)
CY (1) CY1107909T1 (fr)
CZ (1) CZ20011628A3 (fr)
DE (1) DE69937898T2 (fr)
DK (1) DK1128827T3 (fr)
DZ (1) DZ2937A1 (fr)
EA (3) EA200702648A1 (fr)
EG (2) EG22344A (fr)
ES (1) ES2299269T3 (fr)
HK (1) HK1040909B (fr)
HR (2) HRP20010342B1 (fr)
HU (1) HUP0104307A3 (fr)
ID (1) ID29344A (fr)
IL (2) IL143003A0 (fr)
MY (1) MY135973A (fr)
NO (1) NO20012351L (fr)
NZ (2) NZ511611A (fr)
OA (1) OA11676A (fr)
PE (1) PE20001428A1 (fr)
PL (1) PL198717B1 (fr)
PT (1) PT1128827E (fr)
RS (1) RS50208B (fr)
SI (1) SI1128827T1 (fr)
SK (1) SK286937B6 (fr)
TR (2) TR200503846T2 (fr)
TW (2) TWI257305B (fr)
UY (2) UY25798A1 (fr)
WO (1) WO2000028990A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
MY125516A (en) 1999-11-16 2006-08-30 Smithkline Beecham Plc Novel composition based on thiazolidinedione and metformin and use
CA2396237A1 (fr) * 2000-01-07 2001-07-19 Jacob Gabriel Michael Activation selective d'une reponse immunitaire regulee par un lymphocyte th1 ou th2
JP5502254B2 (ja) * 2001-01-31 2014-05-28 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング 少なくとも2種類の異なる被覆ペレット形から成る多粒子剤形
ES2259736T3 (es) * 2001-12-21 2006-10-16 Smithkline Beecham Corporation Regimen de dosificacion para activadores de ppar-gamma-.
MY139719A (en) * 2002-02-12 2009-10-30 Glaxo Group Ltd Oral dosage form for controlled drug release
AU2003281181A1 (en) * 2002-07-11 2004-02-02 Takeda Pharmaceutical Company Limited Process for producing coated preparation
US7018658B2 (en) * 2002-11-14 2006-03-28 Synthon Bv Pharmaceutical pellets comprising tamsulosin
ES2645930T3 (es) * 2003-01-03 2017-12-11 Supernus Pharmaceuticals, Inc. Utilización de una mezcla de dos o más materiales entéricos para regular la liberación de fármacos a través de una membrana o matriz para terapias sistémicas
WO2004067001A1 (fr) 2003-01-29 2004-08-12 Takeda Pharmaceutical Company Limited Procede pour realiser une preparation enrobee
ES2241478B1 (es) * 2004-02-13 2006-11-16 Lacer S.A. Preparacion farmaceutica para la liberacion sostenida de un principio farmaceuticamente activo.
FI20060501A7 (fi) * 2006-05-22 2007-11-23 Biohit Oyj Koostumus ja menetelmä asetaldehydin sitomiseksi mahalaukussa
CA2878866C (fr) * 2011-07-14 2021-02-23 Able Cerebral, Llc Composition, dispositif et procede pour la liberation retardee et prolongee de molecules energeniques pour le cerveau
CA3018328A1 (fr) 2014-10-31 2016-04-30 Purdue Pharma Methodes et compositions destinees au traitement du trouble de deficit d'attention
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS5697277A (en) 1980-01-07 1981-08-05 Takeda Chem Ind Ltd Thiazolidine derivative
JPS6051189A (ja) 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
US4582839A (en) 1984-03-21 1986-04-15 Takeda Chemical Industries, Ltd. 2,4-thiazolidinediones
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
DK173350B1 (da) 1985-02-26 2000-08-07 Sankyo Co Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
JPH06779B2 (ja) 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US4812570A (en) 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
ATE186724T1 (de) 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate
US4791125A (en) 1987-12-02 1988-12-13 Pfizer Inc. Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
WO1989008651A1 (fr) 1988-03-08 1989-09-21 Pfizer Inc. Derives de thiaxolidinedione hypoglycemiques
FI904414A7 (fi) 1988-03-08 1990-09-07 Pfizer Tiatsolidiinidioni-hypoglykeemisesti vaikuttavat aineet
WO1991007107A1 (fr) 1989-11-13 1991-05-30 Pfizer Inc. Agents d'oxazolidinedione hypoglycemiques
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
AU650465B2 (en) 1990-07-03 1994-06-23 Yamanouchi Pharmaceutical Co., Ltd. Bisheterocyclic compound
FI930772L (fi) 1990-08-23 1993-02-22 Pfizer Hydroxiureaderivat som saenker glugosnivao i blodet
JPH04210683A (ja) 1990-12-06 1992-07-31 Terumo Corp チアゾリジン−2,4−ジオン誘導体およびこれを含有する糖尿病合併症治療薬
KR100249988B1 (ko) 1991-04-11 2000-04-01 로렌스 티. 마이젠헬더 티아졸리딘디온 유도체, 그의 제조방법 및 용도
US5183823A (en) 1991-04-11 1993-02-02 Takeda Chemical Industries, Ltd. Pyridine n-oxide compounds which are useful as hypoglycemic and hypolipidemic agents
US5502078A (en) * 1991-05-28 1996-03-26 Zeneca Limited Chemical compounds
TW222626B (fr) 1991-07-22 1994-04-21 Pfizer
FR2680512B1 (fr) 1991-08-20 1995-01-20 Adir Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
JPH05271204A (ja) 1992-03-26 1993-10-19 Japan Tobacco Inc 新規なトリアジン誘導体
US5264451A (en) 1992-04-07 1993-11-23 American Home Products Corporation Process for treating hyperglycemia using trifluoromethyl substituted 3H-pyrazol-3-ones
AU3959193A (en) 1992-04-10 1993-11-18 Smithkline Beecham Plc Heterocyclic compounds and their use in the treatment of type II-diabetes
WO1993022445A1 (fr) 1992-05-05 1993-11-11 The Upjohn Company Procede de production de metabolites de pioglitazone
SK695A3 (en) 1992-07-03 1995-07-11 Smithkline Beecham Plc Heterocyclic compounds method of their production and using
US5326770A (en) * 1992-07-17 1994-07-05 The Du Pont Merck Pharmaceutical Company Monoamine oxidase-B (MAO-B) inhibitory 5-substituted 2,4-thiazolidinediones useful in treating memory disorders of mammals
US5232945A (en) 1992-07-20 1993-08-03 Pfizer Inc. 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5457109A (en) * 1993-09-15 1995-10-10 Warner-Lambert Company Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
TW438587B (en) * 1995-06-20 2001-06-07 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
JP3256841B2 (ja) * 1996-06-27 2002-02-18 武田薬品工業株式会社 ベンズアルデヒド化合物の製造法
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
GB9619757D0 (en) * 1996-09-21 1996-11-06 Knoll Ag Chemical process
IL132032A0 (en) * 1997-03-24 2001-03-19 Galderma Res & Dev Retinoid related molecules for the treatment of non-insulin dependent diabetes mellitus

Also Published As

Publication number Publication date
RS50208B (sr) 2009-07-15
AU768578B2 (en) 2003-12-18
ATE382352T1 (de) 2008-01-15
EP1917962A1 (fr) 2008-05-07
KR20060097140A (ko) 2006-09-13
AU1272900A (en) 2000-06-05
NO20012351D0 (no) 2001-05-11
DZ2937A1 (fr) 2004-03-15
EA200100540A1 (ru) 2001-10-22
KR100732599B1 (ko) 2007-06-27
CA2350659C (fr) 2009-06-09
UY25798A1 (es) 2000-12-29
AP2008004490A0 (en) 2008-06-30
WO2000028990A1 (fr) 2000-05-25
SK286937B6 (sk) 2009-07-06
JP2002529505A (ja) 2002-09-10
CN1333683A (zh) 2002-01-30
AP1901A (en) 2008-10-24
CA2350659A1 (fr) 2000-05-25
NZ526440A (en) 2005-01-28
HRP20080117A2 (en) 2008-10-31
EP1128827B1 (fr) 2008-01-02
NO20012351L (no) 2001-07-04
BR9915215A (pt) 2001-07-31
CO5190673A1 (es) 2002-08-29
PL348153A1 (en) 2002-05-06
SK6432001A3 (en) 2001-12-03
SI1128827T1 (sl) 2008-06-30
EG22344A (en) 2002-12-31
TW200505436A (en) 2005-02-16
EP1128827A1 (fr) 2001-09-05
HK1040909B (en) 2008-08-01
AR023699A1 (es) 2002-09-04
ID29344A (id) 2001-08-23
TR200101337T2 (tr) 2001-11-21
DE69937898D1 (de) 2008-02-14
HUP0104307A3 (en) 2003-12-29
DK1128827T3 (da) 2008-04-28
BG105570A (en) 2002-02-28
CN1289081C (zh) 2006-12-13
EA007608B1 (ru) 2006-12-29
PE20001428A1 (es) 2001-02-08
IL183972A0 (en) 2007-10-31
TR200503846T2 (tr) 2007-01-22
TWI257305B (en) 2006-07-01
EP1815855A1 (fr) 2007-08-08
OA11676A (en) 2005-01-12
KR20010073229A (ko) 2001-07-31
EG24463A (en) 2009-07-16
HRP20010342A2 (en) 2002-06-30
TWI246920B (en) 2006-01-11
ES2299269T3 (es) 2008-05-16
DE69937898T2 (de) 2009-01-02
AR023700A1 (es) 2002-09-04
MY135973A (en) 2008-07-31
BG65444B1 (bg) 2008-08-29
HK1040909A1 (en) 2002-06-28
PT1128827E (pt) 2008-03-10
HUP0104307A2 (hu) 2002-07-29
YU36401A (sh) 2004-05-12
CZ20011628A3 (cs) 2001-12-12
NZ511611A (en) 2003-10-31
EA200601144A1 (ru) 2007-02-27
EA200702648A1 (ru) 2008-10-30
CY1107909T1 (el) 2013-09-04
HRP20010342B1 (en) 2008-04-30
PL198717B1 (pl) 2008-07-31
UY25800A1 (es) 2000-08-21
BG109893A (bg) 2008-11-28

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