ES2015723A6 - Un procedimiento para la preparacion de derivados de l-alanil-l-prolina. - Google Patents
Un procedimiento para la preparacion de derivados de l-alanil-l-prolina.Info
- Publication number
- ES2015723A6 ES2015723A6 ES8902425A ES8902425A ES2015723A6 ES 2015723 A6 ES2015723 A6 ES 2015723A6 ES 8902425 A ES8902425 A ES 8902425A ES 8902425 A ES8902425 A ES 8902425A ES 2015723 A6 ES2015723 A6 ES 2015723A6
- Authority
- ES
- Spain
- Prior art keywords
- formula
- proline
- cpd
- ethyl
- derivs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 3
- 229960002429 proline Drugs 0.000 abstract 3
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Chemical group 0.000 abstract 2
- 239000001257 hydrogen Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 2
- CEIWXEQZZZHLDM-AAEUAGOBSA-N (2s)-2-[[(2s)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid Chemical compound CCOC(=O)[C@@H](N[C@@H](C)C(O)=O)CCC1=CC=CC=C1 CEIWXEQZZZHLDM-AAEUAGOBSA-N 0.000 abstract 1
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- WPWUFUBLGADILS-WDSKDSINSA-N Ala-Pro Chemical compound C[C@H](N)C(=O)N1CCC[C@H]1C(O)=O WPWUFUBLGADILS-WDSKDSINSA-N 0.000 abstract 1
- 229930182821 L-proline Natural products 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 108010087924 alanylproline Proteins 0.000 abstract 1
- 239000011976 maleic acid Substances 0.000 abstract 1
- 239000003495 polar organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| YU135588A YU46919B (sh) | 1988-07-13 | 1988-07-13 | Postupak za dobijanje derivata l-alanil-l-prolina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2015723A6 true ES2015723A6 (es) | 1990-09-01 |
Family
ID=25553829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8902425A Expired - Lifetime ES2015723A6 (es) | 1988-07-13 | 1989-07-10 | Un procedimiento para la preparacion de derivados de l-alanil-l-prolina. |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JP2714447B2 (de) |
| AT (1) | AT394726B (de) |
| DD (1) | DD284028B5 (de) |
| ES (1) | ES2015723A6 (de) |
| NO (1) | NO172894C (de) |
| PL (1) | PL154625B1 (de) |
| SI (1) | SI8811355A (de) |
| SU (1) | SU1757471A3 (de) |
| UA (1) | UA18634A1 (de) |
| YU (1) | YU46919B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5847135A (en) * | 1994-06-17 | 1998-12-08 | Vertex Pharmaceuticals, Incorporated | Inhibitors of interleukin-1β converting enzyme |
| AU2003272077A1 (en) * | 2003-07-31 | 2005-02-14 | Lupin Limited | Alpha-amino acid benzothiazolylthio ester as intermediates for manufacture of ace inhibitors and process for preparation thereof |
| EP2436381A1 (de) * | 2006-06-27 | 2012-04-04 | Sandoz AG | Kristallisierung von Halogenwasserstoffen von pharmazeutischen Verbindungen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4442089A (en) * | 1982-07-06 | 1984-04-10 | E. R. Squibb & Sons, Inc. | Method for treating glaucoma with topical or systemic ACE inhibitor compositions |
| JPS6248696A (ja) * | 1985-08-27 | 1987-03-03 | Kanegafuchi Chem Ind Co Ltd | Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法 |
-
1988
- 1988-07-13 SI SI8811355A patent/SI8811355A/sl unknown
- 1988-07-13 YU YU135588A patent/YU46919B/sh unknown
-
1989
- 1989-07-07 NO NO892813A patent/NO172894C/no unknown
- 1989-07-10 ES ES8902425A patent/ES2015723A6/es not_active Expired - Lifetime
- 1989-07-11 PL PL28052689A patent/PL154625B1/pl unknown
- 1989-07-11 DD DD33068889A patent/DD284028B5/de active IP Right Maintenance
- 1989-07-11 AT AT168189A patent/AT394726B/de not_active IP Right Cessation
- 1989-07-12 SU SU894614532A patent/SU1757471A3/ru active
- 1989-07-12 UA UA4614532A patent/UA18634A1/uk unknown
- 1989-07-13 JP JP1179211A patent/JP2714447B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PL154625B1 (en) | 1991-08-30 |
| YU46919B (sh) | 1994-06-24 |
| UA18634A1 (uk) | 1997-12-25 |
| NO172894B (no) | 1993-06-14 |
| DD284028B5 (de) | 1996-08-08 |
| ATA168189A (de) | 1991-11-15 |
| JPH0272195A (ja) | 1990-03-12 |
| JP2714447B2 (ja) | 1998-02-16 |
| SU1757471A3 (ru) | 1992-08-23 |
| NO892813D0 (no) | 1989-07-07 |
| SI8811355A (en) | 1995-04-30 |
| AT394726B (de) | 1992-06-10 |
| YU135588A (en) | 1990-02-28 |
| NO172894C (no) | 1993-09-22 |
| NO892813L (no) | 1990-01-15 |
| PL280526A1 (en) | 1990-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20040503 |