ES2054880T3 - Metodo de detectar tumores que contengan un defecto genetico del retinoblastoma. - Google Patents

Metodo de detectar tumores que contengan un defecto genetico del retinoblastoma.

Info

Publication number
ES2054880T3
ES2054880T3 ES88906295T ES88906295T ES2054880T3 ES 2054880 T3 ES2054880 T3 ES 2054880T3 ES 88906295 T ES88906295 T ES 88906295T ES 88906295 T ES88906295 T ES 88906295T ES 2054880 T3 ES2054880 T3 ES 2054880T3
Authority
ES
Spain
Prior art keywords
retinoblastoma
tumors containing
detecting tumors
genetic defect
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88906295T
Other languages
English (en)
Inventor
Yuen Kai T Fung
Anne Tang
A Linn Murphree
William F Benedict
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canji Inc
Original Assignee
Canji Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canji Inc filed Critical Canji Inc
Application granted granted Critical
Publication of ES2054880T3 publication Critical patent/ES2054880T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Graft Or Block Polymers (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Un metodo de detectar tumores que contengan un defecto genetico del retinoblastoma, que incluye los pasos de: Hibridación de una sonda génica de retinoblastoma en un ADN extraído de un tejido objeto. Determinación del enlace de la sonda con dicho ADN, seleccionándose dichos tumores del grupo consistente fibrosarcoma, sarcoma de tejido blando, melanoma, carcinoma de pequeñas células del pulmón y carcinoma pecho.
ES88906295T 1987-05-29 1988-05-27 Metodo de detectar tumores que contengan un defecto genetico del retinoblastoma. Expired - Lifetime ES2054880T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878712646A GB8712646D0 (en) 1987-05-29 1987-05-29 Structural evidence

Publications (1)

Publication Number Publication Date
ES2054880T3 true ES2054880T3 (es) 1994-08-16

Family

ID=10618110

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88906295T Expired - Lifetime ES2054880T3 (es) 1987-05-29 1988-05-27 Metodo de detectar tumores que contengan un defecto genetico del retinoblastoma.

Country Status (18)

Country Link
EP (2) EP0364490B1 (es)
JP (1) JPH04500751A (es)
KR (1) KR960002560B1 (es)
AT (1) ATE86673T1 (es)
AU (2) AU1983188A (es)
DE (1) DE3879208T2 (es)
DK (1) DK675088A (es)
ES (1) ES2054880T3 (es)
FI (1) FI895364A0 (es)
GB (1) GB8712646D0 (es)
GR (1) GR3007474T3 (es)
IE (1) IE62296B1 (es)
IL (1) IL86542A (es)
NO (1) NO301774B1 (es)
NZ (1) NZ224822A (es)
PT (1) PT87614B (es)
WO (1) WO1988009387A1 (es)
ZA (1) ZA883805B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853988A (en) * 1986-08-11 1998-12-29 Massachusetts Eye And Ear Infirmary Diagnosis of retinoblastoma
US7384735B1 (en) 1986-08-11 2008-06-10 Massachusetts Eye And Ear Infirmary Retinoblastoma nucleic acids
CA1341576C (en) * 1986-08-11 2008-07-08 Thaddeus P. Dryja Diagnosis of retinoblastoma
US7223842B1 (en) 1986-08-11 2007-05-29 Massachusetts Eye And Ear Infirmary Detection of proteins whose absence is associated with a neoplasm
EP0264274A3 (en) * 1986-10-14 1989-02-01 Canon Kabushiki Kaisha Optical recording medium
US5268267A (en) * 1987-08-21 1993-12-07 The General Hospital Corporation Method for diagnosing small cell carcinoma
AU3038189A (en) * 1988-01-21 1989-08-11 Massachusetts Eye And Ear Infirmary Diagnosis of retinoblastoma
EP0390323B2 (en) * 1989-03-29 2012-08-08 Johns Hopkins University Detection of loss of the wild-type p53 gene
CA2060267A1 (en) * 1991-02-22 1992-08-23 Joe W. Gray Chromosome specific staining to detect genetic rearrangements
DK0667918T3 (da) * 1991-11-14 2000-06-05 Dgi Inc Ikke-radioaktivt hybridiseringsassay og -sæt
WO1994008049A1 (en) * 1992-10-01 1994-04-14 The General Hospital Corporation Functional assay for tumor suppressor genes
JPH06296489A (ja) * 1992-11-20 1994-10-25 Univ Texas Syst 網膜芽腫−関連タンパク質をコードする細胞性遺伝子
US5496731A (en) * 1993-03-25 1996-03-05 Xu; Hong-Ji Broad-spectrum tumor suppressor genes, gene products and methods for tumor suppressor gene therapy
US5969120A (en) * 1993-09-03 1999-10-19 Research Development Foundation Mutants of the RB and P53 genes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341576C (en) * 1986-08-11 2008-07-08 Thaddeus P. Dryja Diagnosis of retinoblastoma

Also Published As

Publication number Publication date
DK675088D0 (da) 1988-12-02
WO1988009387A1 (en) 1988-12-01
AU1983188A (en) 1988-12-21
JPH04500751A (ja) 1992-02-13
AU2038292A (en) 1992-09-24
NO301774B1 (no) 1997-12-08
IE62296B1 (en) 1995-01-25
EP0364490A1 (en) 1990-04-25
IE881613L (en) 1988-11-29
AU657143B2 (en) 1995-03-02
PT87614B (pt) 1993-03-31
KR960002560B1 (ko) 1996-02-22
EP0364490A4 (en) 1990-05-14
EP0293266A3 (en) 1990-04-11
DE3879208T2 (de) 1993-07-22
DK675088A (da) 1988-12-02
ATE86673T1 (de) 1993-03-15
GB8712646D0 (en) 1987-07-01
DE3879208D1 (de) 1993-04-15
IL86542A (en) 1994-02-27
PT87614A (pt) 1988-06-01
NZ224822A (en) 1989-12-21
GR3007474T3 (es) 1993-07-30
FI895364A7 (fi) 1989-11-10
NO885712D0 (no) 1988-12-22
ZA883805B (en) 1990-11-28
FI895364A0 (fi) 1989-11-10
IL86542A0 (en) 1988-11-15
EP0364490B1 (en) 1993-03-10
KR890701763A (ko) 1989-12-21
EP0293266A2 (en) 1988-11-30
NO885712L (no) 1988-12-22

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