ES2084335T3 - Union de sustancias de reconocimiento a liposomas. - Google Patents

Union de sustancias de reconocimiento a liposomas.

Info

Publication number
ES2084335T3
ES2084335T3 ES92900243T ES92900243T ES2084335T3 ES 2084335 T3 ES2084335 T3 ES 2084335T3 ES 92900243 T ES92900243 T ES 92900243T ES 92900243 T ES92900243 T ES 92900243T ES 2084335 T3 ES2084335 T3 ES 2084335T3
Authority
ES
Spain
Prior art keywords
liposomes
recognizing substances
crosslinking reagents
substances
methodologies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92900243T
Other languages
English (en)
Inventor
Rimona Margalit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Application granted granted Critical
Publication of ES2084335T3 publication Critical patent/ES2084335T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE HAN DESARROLLADO METODOLOGIAS Y CIERTAS SUBSTANCIAS DE RECONOCIMIENTO Y SE HAN IDENTIFICADO REAGENTES ENLAZANTES PARA LIPOSOMAS DE MODIFICACION. LOS REAGENTES ENLAZANTES ENLAZAN LOS RESIDUOS SOBRE LA SUPERFICIE LIPOSOMAL A LOS RESIDUOS OFRECIDOS POR CIERTAS SUBSTANCIAS DE RECONOCIMIENTO. LOS REAGENTES ENLAZANTES INCLUYEN GLUTARALDEHIDO (GAD) Y UN CARBODIIMIDO SOLUBLE EN AGUA, PREFERIBLEMENTE, 1-ETIL-3-(3DIMETILAMINOPROPIL)CARBODIIMIDO (EDC). LAS SUBSTANCIAS DE RECONOCIMIENTO INCLUYEN GELATINA, COLAGENO Y ACIDO HIALURONICO (HA). COMO CONSECUENCIA DE ESTAS METODOLOGIAS, PUEDEN UTILIZARSE SUBSTANCIAS DE RECONOCIMIENTO COMO ADHESIVO O PEGAMENTO PARA SUJETAR LOS LIPOSOMAS EN UN AREA DESEADA. ESTOS LIPOSOMAS BIOADHESIVOS OFRECEN VENTAJAS POTENCIAS COMO SISTEMA MICROSCOPICO DE LIBERACION DE MEDICAMENTOS.
ES92900243T 1991-02-14 1991-10-30 Union de sustancias de reconocimiento a liposomas. Expired - Lifetime ES2084335T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65587891A 1991-02-14 1991-02-14

Publications (1)

Publication Number Publication Date
ES2084335T3 true ES2084335T3 (es) 1996-05-01

Family

ID=24630761

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92900243T Expired - Lifetime ES2084335T3 (es) 1991-02-14 1991-10-30 Union de sustancias de reconocimiento a liposomas.

Country Status (10)

Country Link
US (1) US5401511A (es)
EP (1) EP0525132B1 (es)
JP (1) JP3407072B2 (es)
AT (1) ATE132367T1 (es)
AU (1) AU651414B2 (es)
CA (1) CA2079444C (es)
DE (1) DE69116144T2 (es)
DK (1) DK0525132T3 (es)
ES (1) ES2084335T3 (es)
WO (1) WO1992014447A1 (es)

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Also Published As

Publication number Publication date
AU651414B2 (en) 1994-07-21
US5401511A (en) 1995-03-28
DE69116144D1 (de) 1996-02-15
CA2079444C (en) 2004-02-03
DK0525132T3 (da) 1996-02-05
EP0525132B1 (en) 1996-01-03
AU9037091A (en) 1992-09-15
CA2079444A1 (en) 1992-08-15
DE69116144T2 (de) 1996-05-09
JPH05505827A (ja) 1993-08-26
JP3407072B2 (ja) 2003-05-19
WO1992014447A1 (en) 1992-09-03
ATE132367T1 (de) 1996-01-15
EP0525132A1 (en) 1993-02-03

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