ES2093413T3 - Compuestos quimicos. - Google Patents

Compuestos quimicos.

Info

Publication number
ES2093413T3
ES2093413T3 ES93905526T ES93905526T ES2093413T3 ES 2093413 T3 ES2093413 T3 ES 2093413T3 ES 93905526 T ES93905526 T ES 93905526T ES 93905526 T ES93905526 T ES 93905526T ES 2093413 T3 ES2093413 T3 ES 2093413T3
Authority
ES
Spain
Prior art keywords
chemical compounds
lipophilic
biodegradatively
atomo
divisible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93905526T
Other languages
English (en)
Inventor
Jo Klaveness
Keith Redford
Jan Solberg
Per Strande
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed Imaging AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging AS filed Critical Nycomed Imaging AS
Application granted granted Critical
Publication of ES2093413T3 publication Critical patent/ES2093413T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
    • A61K49/1857—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. PLGA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)

Abstract

POLIMEROS NO POLIPEPTIDOS NO DEGRADADOS, CONTENIENDO CADENAS LATERALES LIPOFILICAS, INCORPORANDO UNIDADES DIESTERES DE LA FORMULA R2 REPRESENTAN CADA UNO UN ATOMO DE HIDROGENO O UN GRUPO ORGANICO MONOVALENTE UNIDO AL CARBONO, O R1 Y R2 FORMAN JUNTAMENTE UN GRUPO ORGANICO DIVALENTE UNIDO AL CARBONO) CON LO QUE LAS MITADES LIPOFILICAS SON DIVISIBLES BIODEGRADATIVAMENTE, PARA PRODUCIR UN POLIMERO SOLUBLE EN AGUA.
ES93905526T 1992-03-06 1993-03-05 Compuestos quimicos. Expired - Lifetime ES2093413T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929204918A GB9204918D0 (en) 1992-03-06 1992-03-06 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2093413T3 true ES2093413T3 (es) 1996-12-16

Family

ID=10711636

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93905526T Expired - Lifetime ES2093413T3 (es) 1992-03-06 1993-03-05 Compuestos quimicos.

Country Status (30)

Country Link
US (1) US5574097A (es)
EP (1) EP0629214B1 (es)
JP (1) JP3281381B2 (es)
CN (1) CN1038940C (es)
AT (1) ATE144540T1 (es)
AU (1) AU670069B2 (es)
BG (1) BG99070A (es)
BR (1) BR9306043A (es)
CA (1) CA2130671A1 (es)
CZ (1) CZ281738B6 (es)
DE (1) DE69305628T2 (es)
DK (1) DK0629214T3 (es)
ES (1) ES2093413T3 (es)
FI (1) FI944078A0 (es)
GB (1) GB9204918D0 (es)
GR (1) GR3022075T3 (es)
HU (1) HUT69070A (es)
IL (1) IL104962A (es)
LT (2) LT3199B (es)
LV (1) LV10294B (es)
MD (2) MD940199A (es)
NO (1) NO303123B1 (es)
NZ (1) NZ249547A (es)
OA (1) OA10097A (es)
PH (1) PH30746A (es)
PL (1) PL174125B1 (es)
RU (1) RU2114865C1 (es)
SK (1) SK105694A3 (es)
WO (1) WO1993018070A1 (es)
ZA (2) ZA931599B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
GB9318288D0 (en) * 1993-09-03 1993-10-20 Nycomed Imaging As Improvements in or relating to contrast agents
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
GB9417941D0 (en) * 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents
CA2164237A1 (en) * 1994-12-08 1996-06-09 Takeharu Tabuchi Acrylic monomer
TW503116B (en) * 1997-12-12 2002-09-21 Kimberly Clark Co Structure having balanced pH profile
US6309999B1 (en) * 1999-03-19 2001-10-30 Chandra P. Sharma Process for the preparation of an immunoadsorbent matrix
RU2175338C2 (ru) * 1999-05-05 2001-10-27 Дугуев Сергей Владимирович Способ получения органоминеральных пигментов
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CA2449729C (en) 2001-06-11 2009-11-03 Xenoport, Inc. Prodrugs of gaba analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
AUPR951501A0 (en) * 2001-12-14 2002-01-24 Smart Drug Systems Inc Modified sustained release pharmaceutical system
RU2341296C2 (ru) 2002-05-24 2008-12-20 Энджиотек Интернэшнл Аг Композиции и способы покрытия медицинских имплантатов
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
US20030235610A1 (en) * 2002-06-21 2003-12-25 Piedmont Pharmaceuticals, Llc Liposomes containing biologically active compounds
AU2004293463A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Implantable sensors and implantable pumps and anti-scarring agents
WO2006050514A1 (en) 2004-11-04 2006-05-11 Xenoport, Inc. Gabapentin prodrug sustained release oral dosage forms
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
EP2428235B1 (de) 2007-11-23 2014-06-04 Technische Universität Wien Verwendung von durch Polymerisation härtbaren Zusammensetzungen zur Herstellung biologisch abbaubarer, bioverträglicher, vernetzter Polymere
PL2582733T3 (pl) * 2010-06-17 2014-11-28 Basf Se Polimery z bocznymi grupami sacharydowymi i ich zastosowanie
RU2543895C2 (ru) * 2013-05-17 2015-03-10 Общество С Ограниченной Ответственностью "Научно-Производственный Центр "Амфион" Гидрогелевый материал на основе сшиваемого поливинилового спирта
JP7115914B2 (ja) 2017-06-23 2022-08-09 住友化学株式会社 レジスト組成物及びレジストパターンの製造方法
GB201810788D0 (en) * 2018-06-29 2018-08-15 Biocompatibles Uk Ltd Biodegradable polymer
RU2687231C1 (ru) * 2018-08-03 2019-05-08 Сергей Борисович Врублевский Способ получения пигментов
CN109928879A (zh) * 2019-03-05 2019-06-25 贵州大学 一种丙烯酸酯碳酸酯及其均聚物和共聚物材料
CN111892707B (zh) * 2020-06-18 2021-08-13 中山大学 一种阳离子聚酰胺材料及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180646A (en) * 1975-01-28 1979-12-25 Alza Corporation Novel orthoester polymers and orthocarbonate polymers
US4356166A (en) * 1978-12-08 1982-10-26 University Of Utah Time-release chemical delivery system
US4276885A (en) 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US4718433A (en) 1983-01-27 1988-01-12 Feinstein Steven B Contrast agents for ultrasonic imaging
JPS60501759A (ja) * 1983-07-01 1985-10-17 バテル　メモリアル　インステイチユ−ト 生物分解性ポリペプチド及び薬剤の緩慢な放出のためのその使用
US4741956A (en) * 1986-07-09 1988-05-03 Exxon Research And Engineering Company Biodegradable coatings of ionomer polymer
EP0586875A1 (de) 1988-02-05 1994-03-16 Schering Aktiengesellschaft Ultraschallkontrastmittel, Verfahren zu deren Herstellung und deren Verwendung als Diagnostika und Therapeutika
GB9003821D0 (en) 1990-02-20 1990-04-18 Danbiosyst Uk Diagnostic aid
US5137928A (en) 1990-04-26 1992-08-11 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
PH31064A (en) 1990-09-07 1998-02-05 Nycomed As Of Nycoveten Polymers containing diester units.

Also Published As

Publication number Publication date
ZA931594B (en) 1993-09-27
PL174125B1 (pl) 1998-06-30
OA10097A (en) 1996-12-18
CA2130671A1 (en) 1993-09-07
HU9402563D0 (en) 1994-11-28
JPH07505177A (ja) 1995-06-08
ZA931599B (en) 1993-12-28
LTIP391A (en) 1994-09-25
RU2114865C1 (ru) 1998-07-10
EP0629214A1 (en) 1994-12-21
US5574097A (en) 1996-11-12
LT3216B (en) 1995-04-25
DE69305628D1 (de) 1996-11-28
NZ249547A (en) 1996-08-27
ATE144540T1 (de) 1996-11-15
CZ281738B6 (cs) 1997-01-15
NO943273L (no) 1994-09-05
DE69305628T2 (de) 1997-03-06
LT3199B (en) 1995-03-27
MD940206A (ro) 1996-01-31
CN1038940C (zh) 1998-07-01
NO943273D0 (no) 1994-09-05
LV10294B (en) 1995-12-20
CZ215294A3 (en) 1995-08-16
PH30746A (en) 1997-10-17
IL104962A (en) 1996-01-31
JP3281381B2 (ja) 2002-05-13
DK0629214T3 (da) 1996-11-18
FI944078A7 (fi) 1994-09-05
GR3022075T3 (en) 1997-03-31
FI944078L (fi) 1994-09-05
WO1993018070A1 (en) 1993-09-16
LTIP388A (en) 1994-09-25
AU670069B2 (en) 1996-07-04
RU94045151A (ru) 1996-09-27
BG99070A (bg) 1995-08-28
AU3642393A (en) 1993-10-05
LV10294A (lv) 1994-10-20
IL104962A0 (en) 1993-07-08
MD940199A (ro) 1996-01-31
GB9204918D0 (en) 1992-04-22
BR9306043A (pt) 1997-11-18
SK105694A3 (en) 1995-04-12
HUT69070A (en) 1995-08-28
EP0629214B1 (en) 1996-10-23
CN1084524A (zh) 1994-03-30
NO303123B1 (no) 1998-06-02
FI944078A0 (fi) 1994-09-05

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