MD940199A - Agenţi contrastanţi şi aplicarea acestora - Google Patents

Agenţi contrastanţi şi aplicarea acestora

Info

Publication number
MD940199A
MD940199A MD94-0199A MD940199A MD940199A MD 940199 A MD940199 A MD 940199A MD 940199 A MD940199 A MD 940199A MD 940199 A MD940199 A MD 940199A
Authority
MD
Moldova
Prior art keywords
contrast agents
carbon
application
polymer
gas
Prior art date
Application number
MD94-0199A
Other languages
English (en)
Russian (ru)
Inventor
Jo Klaveness
Keith Redford
Pal Rongved
Jan Solberg
Per Strande
Unni Nordby Wiggen
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of MD940199A publication Critical patent/MD940199A/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
    • A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
    • A61K49/1857—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. PLGA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyamides (AREA)

Abstract

În domeniile de diagnostică ale tehnicii, în special la obţinerea imaginii ultrasonore şi de rezonanţă magnetică, pot fi folosiţi agenţi contrastanţi, care reprezintă microparticule şi/sau microbăşicuţe polimerice, ce conţin sau formează gaze, şi în care polimerul reprezintă un polimer biodescompunător, moleculele căruia conţin verigi cu formula:(O)m-CO-O-C(R1R2)-O-CO-(O)n, (II)în care fiecare din R1 şi R2 reprezintă un atom de hidrogen sau grupe organice monovalente legate cu carbonul sau chiar ele împreună formează o grupă organică bivalentă cu carbonul, iar fiecare din m şi n, independent de altul, reprezintă O sau 1.
MD94-0199A 1992-03-06 1994-07-11 Agenţi contrastanţi şi aplicarea acestora MD940199A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929204918A GB9204918D0 (en) 1992-03-06 1992-03-06 Chemical compounds

Publications (1)

Publication Number Publication Date
MD940199A true MD940199A (ro) 1996-01-31

Family

ID=10711636

Family Applications (2)

Application Number Title Priority Date Filing Date
MD94-0199A MD940199A (ro) 1992-03-06 1994-07-11 Agenţi contrastanţi şi aplicarea acestora
MD94-0206A MD940206A (ro) 1992-03-06 1994-07-14 Polimeri ce se descompun biologic şi procedeu de obţinere a lor

Family Applications After (1)

Application Number Title Priority Date Filing Date
MD94-0206A MD940206A (ro) 1992-03-06 1994-07-14 Polimeri ce se descompun biologic şi procedeu de obţinere a lor

Country Status (30)

Country Link
US (1) US5574097A (ro)
EP (1) EP0629214B1 (ro)
JP (1) JP3281381B2 (ro)
CN (1) CN1038940C (ro)
AT (1) ATE144540T1 (ro)
AU (1) AU670069B2 (ro)
BG (1) BG99070A (ro)
BR (1) BR9306043A (ro)
CA (1) CA2130671A1 (ro)
CZ (1) CZ281738B6 (ro)
DE (1) DE69305628T2 (ro)
DK (1) DK0629214T3 (ro)
ES (1) ES2093413T3 (ro)
FI (1) FI944078A7 (ro)
GB (1) GB9204918D0 (ro)
GR (1) GR3022075T3 (ro)
HU (1) HUT69070A (ro)
IL (1) IL104962A (ro)
LT (2) LT3216B (ro)
LV (1) LV10294B (ro)
MD (2) MD940199A (ro)
NO (1) NO303123B1 (ro)
NZ (1) NZ249547A (ro)
OA (1) OA10097A (ro)
PH (1) PH30746A (ro)
PL (1) PL174125B1 (ro)
RU (1) RU2114865C1 (ro)
SK (1) SK105694A3 (ro)
WO (1) WO1993018070A1 (ro)
ZA (2) ZA931599B (ro)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
GB9318288D0 (en) * 1993-09-03 1993-10-20 Nycomed Imaging As Improvements in or relating to contrast agents
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
GB9417941D0 (en) * 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents
CA2164237A1 (en) * 1994-12-08 1996-06-09 Takeharu Tabuchi Acrylic monomer
TW503116B (en) * 1997-12-12 2002-09-21 Kimberly Clark Co Structure having balanced pH profile
US6309999B1 (en) * 1999-03-19 2001-10-30 Chandra P. Sharma Process for the preparation of an immunoadsorbent matrix
RU2175338C2 (ru) * 1999-05-05 2001-10-27 Дугуев Сергей Владимирович Способ получения органоминеральных пигментов
US6720445B2 (en) 2000-12-21 2004-04-13 Beacon Laboratories, Inc. Acetyloxymethyl esters and methods for using the same
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
ATE540678T1 (de) 2001-06-11 2012-01-15 Xenoport Inc Prodrugs aus gaba-analoga, zusammensetzungen und ihre verwendungen
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
AUPR951501A0 (en) * 2001-12-14 2002-01-24 Smart Drug Systems Inc Modified sustained release pharmaceutical system
EP2075014B9 (en) 2002-05-24 2012-02-01 Angiotech International Ag Compositions and methods for coating medical implants
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
US20030235610A1 (en) * 2002-06-21 2003-12-25 Piedmont Pharmaceuticals, Llc Liposomes containing biologically active compounds
CA2536192A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Soft tissue implants and anti-scarring agents
CA2584338C (en) 2004-11-04 2013-08-06 Xenoport, Inc. Gabapentin prodrug sustained release oral dosage forms
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
JP2011505179A (ja) 2007-11-23 2011-02-24 テヒニーシェ ウニヴェルジテート ウィーン ポリビニルアルコールベースの生分解性、生体適合性、架橋ポリマーの調製用重合硬化性組成物
ES2485899T3 (es) * 2010-06-17 2014-08-14 Basf Se Polímeros con grupos laterales sacárido y su uso
RU2543895C2 (ru) * 2013-05-17 2015-03-10 Общество С Ограниченной Ответственностью "Научно-Производственный Центр "Амфион" Гидрогелевый материал на основе сшиваемого поливинилового спирта
JP7115914B2 (ja) 2017-06-23 2022-08-09 住友化学株式会社 レジスト組成物及びレジストパターンの製造方法
GB201810788D0 (en) * 2018-06-29 2018-08-15 Biocompatibles Uk Ltd Biodegradable polymer
RU2687231C1 (ru) * 2018-08-03 2019-05-08 Сергей Борисович Врублевский Способ получения пигментов
CN109928879A (zh) * 2019-03-05 2019-06-25 贵州大学 一种丙烯酸酯碳酸酯及其均聚物和共聚物材料
CN111892707B (zh) * 2020-06-18 2021-08-13 中山大学 一种阳离子聚酰胺材料及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180646A (en) 1975-01-28 1979-12-25 Alza Corporation Novel orthoester polymers and orthocarbonate polymers
US4356166A (en) * 1978-12-08 1982-10-26 University Of Utah Time-release chemical delivery system
US4276885A (en) 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US4718433A (en) 1983-01-27 1988-01-12 Feinstein Steven B Contrast agents for ultrasonic imaging
DE3463211D1 (en) 1983-07-01 1987-05-21 Battelle Memorial Institute Biodegradable polypeptide and its use in the sustained release of medicaments
US4741956A (en) * 1986-07-09 1988-05-03 Exxon Research And Engineering Company Biodegradable coatings of ionomer polymer
DE58908194D1 (de) 1988-02-05 1994-09-22 Schering Ag Ultraschallkontrastmittel, verfahren zu deren herstellung und deren verwendung als diagnostika und therapeutika.
GB9003821D0 (en) 1990-02-20 1990-04-18 Danbiosyst Uk Diagnostic aid
US5137928A (en) 1990-04-26 1992-08-11 Hoechst Aktiengesellschaft Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
PH31064A (en) 1990-09-07 1998-02-05 Nycomed As Of Nycoveten Polymers containing diester units.

Also Published As

Publication number Publication date
AU670069B2 (en) 1996-07-04
GB9204918D0 (en) 1992-04-22
BG99070A (bg) 1995-08-28
LTIP391A (en) 1994-09-25
CZ281738B6 (cs) 1997-01-15
DK0629214T3 (da) 1996-11-18
OA10097A (en) 1996-12-18
CN1038940C (zh) 1998-07-01
GR3022075T3 (en) 1997-03-31
NO943273L (no) 1994-09-05
AU3642393A (en) 1993-10-05
ZA931594B (en) 1993-09-27
JPH07505177A (ja) 1995-06-08
JP3281381B2 (ja) 2002-05-13
RU94045151A (ru) 1996-09-27
EP0629214B1 (en) 1996-10-23
HU9402563D0 (en) 1994-11-28
BR9306043A (pt) 1997-11-18
RU2114865C1 (ru) 1998-07-10
PL174125B1 (pl) 1998-06-30
WO1993018070A1 (en) 1993-09-16
IL104962A (en) 1996-01-31
SK105694A3 (en) 1995-04-12
LT3216B (en) 1995-04-25
PH30746A (en) 1997-10-17
DE69305628D1 (de) 1996-11-28
ES2093413T3 (es) 1996-12-16
EP0629214A1 (en) 1994-12-21
ZA931599B (en) 1993-12-28
FI944078A0 (fi) 1994-09-05
US5574097A (en) 1996-11-12
LT3199B (en) 1995-03-27
NO303123B1 (no) 1998-06-02
LTIP388A (en) 1994-09-25
DE69305628T2 (de) 1997-03-06
MD940206A (ro) 1996-01-31
FI944078L (fi) 1994-09-05
NO943273D0 (no) 1994-09-05
LV10294B (en) 1995-12-20
FI944078A7 (fi) 1994-09-05
CA2130671A1 (en) 1993-09-07
HUT69070A (en) 1995-08-28
CN1084524A (zh) 1994-03-30
ATE144540T1 (de) 1996-11-15
CZ215294A3 (en) 1995-08-16
IL104962A0 (en) 1993-07-08
NZ249547A (en) 1996-08-27
LV10294A (lv) 1994-10-20

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