ES2098948T3 - Procedimientos de ensayo de analogos de acido nucleico. - Google Patents
Procedimientos de ensayo de analogos de acido nucleico.Info
- Publication number
- ES2098948T3 ES2098948T3 ES94916331T ES94916331T ES2098948T3 ES 2098948 T3 ES2098948 T3 ES 2098948T3 ES 94916331 T ES94916331 T ES 94916331T ES 94916331 T ES94916331 T ES 94916331T ES 2098948 T3 ES2098948 T3 ES 2098948T3
- Authority
- ES
- Spain
- Prior art keywords
- nucleic acid
- acid analog
- amount
- test procedures
- analog test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 238000010998 test method Methods 0.000 title abstract 2
- 230000003321 amplification Effects 0.000 abstract 3
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000009834 selective interaction Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
UN PROCEDIMIENTO DE ENSAYO PARA CUANTIFICAR LA CANTIDAD DE UNA MUESTRA INICIADORA EN UN PROCEDIMIENTO DE AMPLIFICACION DE ACIDO NUCLEICO TAL COMO PCR QUE INVOLUCRA INTENTAR LA AMPLIFICACION EN LA PRESENCIA DE VARIAS CANTIDADES DE UN ANALOGO DE UN ACIDO NUCLEICO EN SUFICIENTE CANTIDAD PARA INHIBIR DICHO PROCEDIMIENTO DE AMPLIFICACION MEDIANTE LA INTERACCION SELECTIVA CON ESPECIES DE ACIDO NUCLEICO PRESENTES, POR EJEMPLO UN PNA COMO DESCRITO EN WO-02-20703. LA CANTIDAD DE LA MUESTRA ES DADA POR LA CANTIDAD DEL ANALOGO DE ACIDO NUCLEICO QUE ES CRITICO PARA CAUSAR EL FALLO DE DICHO PROCEDIMIENTO DE AMPLIFICACION.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939311386A GB9311386D0 (en) | 1993-06-02 | 1993-06-02 | Nucleic acid analogue assay procedures |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2098948T3 true ES2098948T3 (es) | 1997-05-01 |
Family
ID=10736511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94916331T Expired - Lifetime ES2098948T3 (es) | 1993-06-02 | 1994-05-31 | Procedimientos de ensayo de analogos de acido nucleico. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5912145A (es) |
| EP (1) | EP0701627B1 (es) |
| JP (1) | JP2842694B2 (es) |
| AU (1) | AU6802994A (es) |
| DE (1) | DE69401661T2 (es) |
| DK (1) | DK0701627T3 (es) |
| ES (1) | ES2098948T3 (es) |
| GB (1) | GB9311386D0 (es) |
| WO (1) | WO1994028171A1 (es) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5629178A (en) * | 1994-10-28 | 1997-05-13 | Genetics & Ivf Institute | Method for enhancing amplification in the polymerase chain reaction employing peptide nucleic acid (PNA) |
| EP0826066B1 (en) | 1995-05-05 | 2000-09-13 | The Perkin-Elmer Corporation | Methods and reagents for combined pcr amplification and hybridization probing assay |
| US5939262A (en) | 1996-07-03 | 1999-08-17 | Ambion, Inc. | Ribonuclease resistant RNA preparation and utilization |
| US5677124A (en) * | 1996-07-03 | 1997-10-14 | Ambion, Inc. | Ribonuclease resistant viral RNA standards |
| US6617422B1 (en) | 1997-05-23 | 2003-09-09 | Peter Nielsen | Peptide nucleic acid monomers and oligomers |
| US6485901B1 (en) | 1997-10-27 | 2002-11-26 | Boston Probes, Inc. | Methods, kits and compositions pertaining to linear beacons |
| DK1471926T3 (da) | 1999-06-01 | 2011-02-28 | Baylor College Medicine | Sammensætninger og fremgangsmåder til terapeutisk anvendelse af en atonal-associeret sekvens |
| WO2001051669A2 (en) * | 2000-01-15 | 2001-07-19 | Genelabs Technologies, Inc. | Nucleic acid binding assay and selection method |
| EP3415625A1 (en) | 2002-02-01 | 2018-12-19 | Life Technologies Corporation | Double-stranded oligonucleotides |
| WO2003064621A2 (en) | 2002-02-01 | 2003-08-07 | Ambion, Inc. | HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES |
| US20060009409A1 (en) | 2002-02-01 | 2006-01-12 | Woolf Tod M | Double-stranded oligonucleotides |
| US20030211483A1 (en) * | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
| EP2269619A1 (en) | 2002-08-12 | 2011-01-05 | Jennerex Biotherapeutics ULC | Methods and compositions concerning poxviruses and cancer |
| ES2345993T3 (es) | 2004-09-14 | 2010-10-07 | The Regents Of The University Of Colorado, A Body Corporate | Metodo para el tratamiento con bucindolol basado en direccionamiento genetico. |
| CA2842402C (en) | 2005-03-10 | 2016-02-23 | Gen-Probe Incorporated | Systems and methods to perform assays for detecting or quantifying analytes within samples |
| CN101351213B (zh) * | 2005-09-07 | 2013-10-02 | 詹纳里克斯公司 | 使用表达gm-csf的痘病毒系统性治疗转移性癌和/或全身散布性癌 |
| US8980246B2 (en) | 2005-09-07 | 2015-03-17 | Sillajen Biotherapeutics, Inc. | Oncolytic vaccinia virus cancer therapy |
| DE602007006478D1 (de) | 2006-05-12 | 2010-06-24 | Cepheid Sunnyvale | Erkennung der verbindung einer dna-rekombination |
| CN102026645B (zh) | 2006-09-15 | 2016-01-27 | 渥太华医院研究机构 | 溶瘤弹状病毒 |
| US20100129902A1 (en) * | 2008-11-24 | 2010-05-27 | Erhard Ralf Schoenbrunner | Replication Stable and RNase Resistant Chimeras of Pestivirus with Insertion in 3' Nontranslated Region (3'NTR) |
| JP5785942B2 (ja) | 2009-06-29 | 2015-09-30 | ルミネックス コーポレーション | ヘアピンコンフォメーションを有するキメラプライマーおよびその使用法 |
| US9409983B2 (en) | 2009-07-23 | 2016-08-09 | The Board Of Trustess Of The University Of Illinois | Methods and compositions involving PBEF inhibitors for lung inflammation conditions and diseases |
| WO2011032088A1 (en) | 2009-09-11 | 2011-03-17 | Arca Biopharma, Inc. | Polymorphisms in the pde3a gene |
| ES2671570T3 (es) | 2009-09-14 | 2018-06-07 | Sillajen Biotherapeutics, Inc. | Terapia combinada contra el cáncer con virus oncolítico de vaccinia |
| WO2011070440A2 (en) | 2009-12-10 | 2011-06-16 | Ottawa Hospital Research Institute | Oncolytic rhabdovirus |
| WO2011079273A2 (en) | 2009-12-23 | 2011-06-30 | Arca Biopharma, Inc. | Methods and compositions for cardiovascular diseases and conditions |
| CN103429258B (zh) | 2011-01-04 | 2016-03-09 | 新罗杰公司 | 通过施用溶瘤痘苗病毒生成针对肿瘤抗原的抗体和生成肿瘤特异性补体依赖性细胞毒性 |
| MX2013009863A (es) | 2011-02-28 | 2013-12-06 | Univ Iowa Res Found | Cambios de la hormona anti-mulleriana en el embarazo y prediccion de sexo y de resultados adversos en el embarazo. |
| AU2012226530B2 (en) | 2011-03-08 | 2016-12-01 | King Abdullah University Of Science And Technology | Molecular biomarker set for early detection of ovarian cancer |
| US9364532B2 (en) | 2011-06-08 | 2016-06-14 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Compositions and methods for glioblastoma treatment |
| US10040853B2 (en) | 2011-09-09 | 2018-08-07 | Fred Hutchinson Cancer Research Center | Methods and compositions involving NKG2D inhibitors and cancer |
| US10125373B2 (en) | 2013-01-22 | 2018-11-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
| JP2016513115A (ja) | 2013-02-21 | 2016-05-12 | チルドレンズ ホスピタル オブ イースタン オンタリオ リサーチ インスティチュート インコーポレイテッド | ワクチン組成物 |
| AU2014329535B2 (en) | 2013-10-03 | 2017-09-07 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
| CN106103431B (zh) | 2014-01-10 | 2019-03-15 | 葛兰素史密斯克莱知识产权(第2 号)有限公司 | 羟基甲酰胺衍生物及其用途 |
| GB201411567D0 (en) * | 2014-06-30 | 2014-08-13 | Epistem Ltd | Quantification methods |
| EP3224362B1 (en) | 2014-11-26 | 2024-09-25 | The Regents of The University of California | Therapeutic compositions comprising transcription factors and methods of making and using the same |
| WO2018140606A1 (en) | 2017-01-26 | 2018-08-02 | Oklahoma Medical Research Foundation | Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare |
| US12140592B2 (en) | 2017-06-16 | 2024-11-12 | Oklahoma Medical Research Foundation | Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis |
| US20210349088A1 (en) | 2018-10-18 | 2021-11-11 | Oklahoma Medical Research Foundation | Biomarkers For A Systemic Lupus Erythematosus (SLE) Disease Activity Immune Index That Characterizes Disease Activity |
| US12510539B2 (en) | 2018-10-18 | 2025-12-30 | Progentec Diagnostics, Inc. | Biomarkers for a systemic lupus erythematosus (SLE) disease activity immune index that characterizes disease activity |
| ES2975662T3 (es) | 2018-10-31 | 2024-07-11 | Univ Arizona | Biomarcadores y métodos de uso para la lesión pulmonar inducida por radiación |
| WO2021055489A1 (en) | 2019-09-16 | 2021-03-25 | Grohar Patrick J | Compositions and methods for the treatment of swi-snf mutant tumors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5219727A (en) * | 1989-08-21 | 1993-06-15 | Hoffmann-Laroche Inc. | Quantitation of nucleic acids using the polymerase chain reaction |
| GB9016163D0 (en) * | 1990-07-24 | 1990-09-05 | Cemu Bioteknik | Chemical method |
| DK51092D0 (da) * | 1991-05-24 | 1992-04-15 | Ole Buchardt | Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf |
| GB9211979D0 (en) * | 1992-06-05 | 1992-07-15 | Buchard Ole | Uses of nucleic acid analogues |
-
1993
- 1993-06-02 GB GB939311386A patent/GB9311386D0/en active Pending
-
1994
- 1994-05-31 US US08/549,786 patent/US5912145A/en not_active Expired - Lifetime
- 1994-05-31 DK DK94916331.5T patent/DK0701627T3/da active
- 1994-05-31 EP EP94916331A patent/EP0701627B1/en not_active Expired - Lifetime
- 1994-05-31 AU AU68029/94A patent/AU6802994A/en not_active Abandoned
- 1994-05-31 ES ES94916331T patent/ES2098948T3/es not_active Expired - Lifetime
- 1994-05-31 DE DE69401661T patent/DE69401661T2/de not_active Expired - Lifetime
- 1994-05-31 WO PCT/GB1994/001174 patent/WO1994028171A1/en not_active Ceased
- 1994-05-31 JP JP7500415A patent/JP2842694B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69401661D1 (de) | 1997-03-13 |
| EP0701627B1 (en) | 1997-01-29 |
| US5912145A (en) | 1999-06-15 |
| DE69401661T2 (de) | 1997-06-12 |
| EP0701627A1 (en) | 1996-03-20 |
| DK0701627T3 (da) | 1997-07-21 |
| AU6802994A (en) | 1994-12-20 |
| JPH08510384A (ja) | 1996-11-05 |
| GB9311386D0 (en) | 1993-07-21 |
| WO1994028171A1 (en) | 1994-12-08 |
| JP2842694B2 (ja) | 1999-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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