ES2104441T3 - Procedimiento para la preparacion de diclorhidrato de azitromicina. - Google Patents

Procedimiento para la preparacion de diclorhidrato de azitromicina.

Info

Publication number
ES2104441T3
ES2104441T3 ES95105285T ES95105285T ES2104441T3 ES 2104441 T3 ES2104441 T3 ES 2104441T3 ES 95105285 T ES95105285 T ES 95105285T ES 95105285 T ES95105285 T ES 95105285T ES 2104441 T3 ES2104441 T3 ES 2104441T3
Authority
ES
Spain
Prior art keywords
preparation
dichlorhydrate
azythromycin
procedure
azithromycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95105285T
Other languages
English (en)
Inventor
Nevenka Lopotar
Stjepen Mutak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pliva Farmaceutika dd
Original Assignee
Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd filed Critical Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd
Application granted granted Critical
Publication of ES2104441T3 publication Critical patent/ES2104441T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

EL PRESENTE INVENTO DESCRIBE UN NUEVO PROCESO PARA LA PREPARACION DE DIHIDROCLORURO DE ACITROMICINA, QUE ES UNA SAL FARMACEUTICAMENTE ACEPTABLE DE EL ANTIBIOTICO ACITROMICINA UTIL COMO AGENTE ANTIBACTERIANO CON AMPLIO CAMPO DE ACCION.
ES95105285T 1994-04-15 1995-04-07 Procedimiento para la preparacion de diclorhidrato de azitromicina. Expired - Lifetime ES2104441T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR940251A HRP940251B1 (en) 1994-04-15 1994-04-15 Process for the preparation of azithromycin dihydrochloride

Publications (1)

Publication Number Publication Date
ES2104441T3 true ES2104441T3 (es) 1997-10-01

Family

ID=10946105

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95105285T Expired - Lifetime ES2104441T3 (es) 1994-04-15 1995-04-07 Procedimiento para la preparacion de diclorhidrato de azitromicina.

Country Status (16)

Country Link
EP (1) EP0677530B1 (es)
JP (1) JP3075681B2 (es)
CN (1) CN1042033C (es)
AT (1) ATE154028T1 (es)
BG (1) BG61769B1 (es)
CA (1) CA2146475C (es)
DE (1) DE69500327T2 (es)
ES (1) ES2104441T3 (es)
HR (1) HRP940251B1 (es)
HU (1) HU217553B (es)
PL (1) PL177292B1 (es)
RO (1) RO113737B1 (es)
RU (1) RU2134271C1 (es)
SI (1) SI9500124A (es)
SK (1) SK281178B6 (es)
UA (1) UA41902C2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
KR100431431B1 (ko) * 2001-04-25 2004-05-14 한미약품 주식회사 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
ATE421882T1 (de) 2003-07-24 2009-02-15 Pliva Hrvatska D O O Schnellösliches azithromycin in einzeldosisform
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
CN100343267C (zh) * 2005-08-05 2007-10-17 新昌国邦化学工业有限公司 阿奇霉素酒石酸盐的制备方法
CN100427499C (zh) * 2005-12-20 2008-10-22 山东诚创医药技术开发有限公司 一种阿奇霉素的可溶性盐及其制备方法
CN101092440B (zh) * 2007-07-19 2010-05-26 浙江尖峰药业有限公司 硫酸阿奇霉素的制备方法
CN102746350A (zh) * 2011-04-21 2012-10-24 常州泰康制药有限公司 盐酸阿奇霉素的制备方法
CN104045674B (zh) * 2014-05-21 2017-01-04 丽珠医药集团股份有限公司 一种阿奇霉素的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1100504A (en) 1967-08-16 1968-01-24 Pliva Pharm & Chem Works Erythromycin oxime and 9-amino-3-o-cladinosyl-5-o-desosaminyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
YU43658B (en) * 1983-07-18 1989-10-31 Pliva Pharm & Chem Works Process for preparing 7,16-dioxa-2-aza-10-0-cladinosyl-12,0-desosaminyl-4,5-dihydroxy-6-ethyl-3,5,9,11,13,15-hexamethyl-bicyclo(11.2.1)hexadeca-1(2)-ene-8
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions

Also Published As

Publication number Publication date
DE69500327D1 (de) 1997-07-10
DE69500327T2 (de) 1998-01-08
JP3075681B2 (ja) 2000-08-14
ATE154028T1 (de) 1997-06-15
HRP940251B1 (en) 1998-12-31
PL308095A1 (en) 1995-10-16
BG99580A (bg) 1995-12-29
RU2134271C1 (ru) 1999-08-10
BG61769B1 (bg) 1998-05-29
HRP940251A2 (en) 1997-06-30
CA2146475C (en) 1999-06-29
HU9501084D0 (en) 1995-06-28
PL177292B1 (pl) 1999-10-29
CA2146475A1 (en) 1995-10-16
HU217553B (hu) 2000-02-28
EP0677530A1 (en) 1995-10-18
CN1112566A (zh) 1995-11-29
HUT71840A (en) 1996-02-28
EP0677530B1 (en) 1997-06-04
SK281178B6 (sk) 2000-12-11
CN1042033C (zh) 1999-02-10
JPH0841058A (ja) 1996-02-13
SK49195A3 (en) 1995-11-08
RO113737B1 (ro) 1998-10-30
RU95105596A (ru) 1997-01-10
SI9500124A (en) 1995-10-31
UA41902C2 (uk) 2001-10-15

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