ES2104697T3 - Formulados farmaceuticos. - Google Patents
Formulados farmaceuticos.Info
- Publication number
- ES2104697T3 ES2104697T3 ES91907052T ES91907052T ES2104697T3 ES 2104697 T3 ES2104697 T3 ES 2104697T3 ES 91907052 T ES91907052 T ES 91907052T ES 91907052 T ES91907052 T ES 91907052T ES 2104697 T3 ES2104697 T3 ES 2104697T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical
- formulates
- alfaglycerol
- formulation
- biologically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- -1 ERYTHROPOIETINE Chemical compound 0.000 abstract 1
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- BBBFJLBPOGFECG-UHFFFAOYSA-N salmon calcitonin Chemical compound C=1N=CNC=1CC(C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CC=1C=CC(O)=CC=1)C(=O)N1C(CCC1)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N1C(CCC1)C(N)=O)NC(=O)C(CC(C)C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C1CSSCC(N)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N1 BBBFJLBPOGFECG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE PRESENTA UNA FORMULACION FARMACEUTICA QUE COMPRENDE UN MATERIAL BIOLOGICAMENTE ACTIVO TAL COMO INSULINA, ERITROPOIETINA, CALCITONINA Y HORMONA DE CRECIMIENTO, Y, ASOCIADO CON ELLOS, UN FOSFOLIPIDO PARA FORMAR UN MATERIAL QUE SE PRECIPITA EN ALFAGLICEROL PARA LA FORMACION DE LECITINAS QUE SE HAN ENCONTRADO EN LAS CELULAS HEPITELIALES INTESTINALES. LAS PROTEINAS BIOLOGICAMENTE ACTIVAS ADMINISTRADAS ORALMENTE DE ESTA FORMULACION SE ENCUENTRAN BIODISPONIBLES Y SON BIOACTIVAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909007052A GB9007052D0 (en) | 1990-03-29 | 1990-03-29 | Pharmaceutical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2104697T3 true ES2104697T3 (es) | 1997-10-16 |
Family
ID=10673486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91907052T Expired - Lifetime ES2104697T3 (es) | 1990-03-29 | 1991-04-02 | Formulados farmaceuticos. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5665700A (es) |
| EP (1) | EP0521994B1 (es) |
| JP (1) | JPH05505192A (es) |
| KR (1) | KR100197915B1 (es) |
| AT (1) | ATE154515T1 (es) |
| AU (1) | AU656134B2 (es) |
| CA (1) | CA2079233A1 (es) |
| CS (1) | CS88091A2 (es) |
| DE (1) | DE69126609T2 (es) |
| DK (1) | DK0521994T3 (es) |
| ES (1) | ES2104697T3 (es) |
| FI (1) | FI101043B (es) |
| GB (1) | GB9007052D0 (es) |
| GR (1) | GR3024745T3 (es) |
| HK (1) | HK1004531A1 (es) |
| HU (2) | HUT63341A (es) |
| IE (1) | IE911086A1 (es) |
| NO (1) | NO923768D0 (es) |
| NZ (1) | NZ237667A (es) |
| PT (1) | PT97199B (es) |
| RU (1) | RU2104715C1 (es) |
| SG (1) | SG54998A1 (es) |
| WO (1) | WO1991014454A1 (es) |
| ZA (1) | ZA912411B (es) |
Families Citing this family (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981485A (en) | 1997-07-14 | 1999-11-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
| US6099856A (en) | 1992-06-15 | 2000-08-08 | Emisphere Technologies, Inc. | Active agent transport systems |
| US5714167A (en) | 1992-06-15 | 1998-02-03 | Emisphere Technologies, Inc. | Active agent transport systems |
| US5693338A (en) | 1994-09-29 | 1997-12-02 | Emisphere Technologies, Inc. | Diketopiperazine-based delivery systems |
| US6221367B1 (en) | 1992-06-15 | 2001-04-24 | Emisphere Technologies, Inc. | Active agent transport systems |
| US5578323A (en) | 1992-06-15 | 1996-11-26 | Emisphere Technologies, Inc. | Proteinoid carriers and methods for preparation and use thereof |
| US5206219A (en) * | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
| EP0566135A1 (en) * | 1992-04-17 | 1993-10-20 | Takeda Chemical Industries, Ltd. | Transmucosal composition comprising a peptide and a cytidine derivative |
| US6916489B2 (en) * | 1992-06-15 | 2005-07-12 | Emisphere Technologies, Inc. | Active agent transport systems |
| DK0955062T3 (da) * | 1992-07-31 | 2007-09-17 | Genentech Inc | Vandig formulering indeholdende humant væksthormon |
| US5464696A (en) * | 1992-08-13 | 1995-11-07 | Bracco International B.V. | Particles for NMR imaging |
| US6461643B2 (en) | 1993-04-22 | 2002-10-08 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
| US20010003001A1 (en) * | 1993-04-22 | 2001-06-07 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5514670A (en) * | 1993-08-13 | 1996-05-07 | Pharmos Corporation | Submicron emulsions for delivery of peptides |
| US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
| ATE180423T1 (de) * | 1993-09-29 | 1999-06-15 | Technobiochip | Duenne proteinschichten und zusammensetzungen zu ihrer herstellung |
| CA2175494C (en) * | 1993-11-03 | 2000-09-19 | Young W. Cho | Microparticular pharmaceutical compositions |
| EP0788346B9 (en) * | 1994-03-18 | 2007-02-14 | Supernus Pharmaceuticals, Inc. | Emulsified drug delivery systems |
| US5851510A (en) * | 1994-05-16 | 1998-12-22 | The Board Of Regents Of The University Of Michigan | Hepatocyte-selective oil-in-water emulsion |
| US5858398A (en) * | 1994-11-03 | 1999-01-12 | Isomed Inc. | Microparticular pharmaceutical compositions |
| GB9424902D0 (en) * | 1994-12-09 | 1995-02-08 | Cortecs Ltd | Solubilisation Aids |
| CN1151836C (zh) | 1995-03-31 | 2004-06-02 | 艾米斯菲尔技术有限公司 | 用作传送活性剂的化合物和组合物 |
| US5866536A (en) | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6090958A (en) | 1995-03-31 | 2000-07-18 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5989539A (en) | 1995-03-31 | 1999-11-23 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6001347A (en) | 1995-03-31 | 1999-12-14 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5750147A (en) | 1995-06-07 | 1998-05-12 | Emisphere Technologies, Inc. | Method of solubilizing and encapsulating itraconazole |
| GB2320248B (en) | 1995-09-11 | 1999-04-14 | Emisphere Tech Inc | Method for preparing omega-aminoalkanoic acid derivatives from cycloalkanones |
| US5912014A (en) * | 1996-03-15 | 1999-06-15 | Unigene Laboratories, Inc. | Oral salmon calcitonin pharmaceutical products |
| IL126318A (en) | 1996-03-29 | 2004-09-27 | Emisphere Tech Inc | Compounds and compositions for delivering active agents and some novel carrier compounds |
| US6063370A (en) * | 1996-04-05 | 2000-05-16 | The Board Of Trustees Of The University Of Illinois | Macromolecular complexes for drug delivery |
| CA2258264A1 (en) | 1996-06-14 | 1997-12-18 | Emisphere Technologies, Inc. | Microencapsulated fragrances and method for preparation |
| DE19724845A1 (de) * | 1996-08-28 | 1998-03-05 | Solvay Pharm Gmbh | Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen |
| GB9625589D0 (en) | 1996-12-10 | 1997-01-29 | Boots Co Plc | Therapeutic agents |
| US5990166A (en) | 1997-02-07 | 1999-11-23 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6060513A (en) | 1997-02-07 | 2000-05-09 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6358504B1 (en) | 1997-02-07 | 2002-03-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5804688A (en) | 1997-02-07 | 1998-09-08 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US6313088B1 (en) | 1997-02-07 | 2001-11-06 | Emisphere Technologies, Inc. | 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents |
| US5773647A (en) * | 1997-02-07 | 1998-06-30 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5830432A (en) * | 1997-03-31 | 1998-11-03 | Amur Pharmacuticals, Inc. | Phospholipid drug derivatives |
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| US5962710A (en) | 1997-05-09 | 1999-10-05 | Emisphere Technologies, Inc. | Method of preparing salicyloylamino acids |
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| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
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| US6956048B2 (en) | 1999-03-31 | 2005-10-18 | Pharmacia & Upjohn Company | Pharmaceutical emulsions for retroviral protease inhibitors |
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| US7556827B1 (en) * | 1999-08-06 | 2009-07-07 | Max-Delbrück-Centrum-für Molekulare Medizin | Implantable active ingredient depot |
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| US6417237B1 (en) | 2000-06-08 | 2002-07-09 | The Board Of Trustees Of The University Of Illinois | Macromolecular drug complexes and compositions containing the same |
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| CA2560613C (en) | 2004-03-22 | 2015-11-24 | Solvay Pharmaceuticals Gmbh | Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants |
| US8449867B2 (en) | 2004-08-31 | 2013-05-28 | Stiefel Research Australia Pty Ltd | Microemulsion and sub-micron emulsion process and compositions |
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| RU2411039C2 (ru) * | 2007-12-26 | 2011-02-10 | Валентина Васильевна Малиновская | Иммунокорригирующее средство для лечения заболеваний вирусной этиологии |
| RU2367472C1 (ru) * | 2008-03-17 | 2009-09-20 | Общество С Ограниченной Ответственностью "Технология Лекарств" | Парентеральное лекарственное средство и способ его получения |
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| CN113769074A (zh) | 2012-02-01 | 2021-12-10 | 奥拉姆德有限公司 | 含有蛋白酶抑制物的组合物、包含前者的组合物和用于产生和使用前者的方法 |
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| EP3820455B1 (en) * | 2018-07-10 | 2024-06-19 | Universidade de Santiago de Compostela | Nanostructure lipid system |
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| GB1180996A (en) * | 1967-08-30 | 1970-02-11 | Inst Rech S Chimiques Et Biolo | Solubilised Cytochrome C-phospholipid Complexes |
| US4164573A (en) * | 1975-06-13 | 1979-08-14 | Galinsky Alvin M | Composition and method for making a suppository for introducing a hypoglycemic agent into a mammal |
| JPS5517328A (en) * | 1978-07-21 | 1980-02-06 | Tanabe Seiyaku Co Ltd | Insulin-containing emulsion and its preparation |
| JPS5770814A (en) * | 1980-10-17 | 1982-05-01 | Isamu Horikoshi | Oral preparation of blood clotting eighth factor |
| NL193099C (nl) * | 1981-10-30 | 1998-11-03 | Novo Industri As | Gestabiliseerde insuline-oplossing. |
| JPS6058915A (ja) * | 1983-09-12 | 1985-04-05 | Fujisawa Pharmaceut Co Ltd | 薬物含有脂質小胞体製剤 |
| FR2581543B1 (fr) * | 1985-05-09 | 1989-07-07 | Tressens Dominique | Pharmacotechnie permettant la realisation d'une preparation insulinique active par voie orale |
| US4849227A (en) * | 1986-03-21 | 1989-07-18 | Eurasiam Laboratories, Inc. | Pharmaceutical compositions |
| DE3750369T2 (de) * | 1986-03-21 | 1995-05-24 | Eurasiam Lab | Arzneimittelzusammensetzungen. |
| NZ222907A (en) * | 1986-12-16 | 1990-08-28 | Novo Industri As | Preparation for intranasal administration containing a phospholipid absorption enhancing system |
| AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
-
1990
- 1990-03-29 GB GB909007052A patent/GB9007052D0/en active Pending
-
1991
- 1991-03-28 IE IE108691A patent/IE911086A1/en unknown
- 1991-03-28 PT PT97199A patent/PT97199B/pt not_active IP Right Cessation
- 1991-03-28 ZA ZA912411A patent/ZA912411B/xx unknown
- 1991-03-29 CS CS91880A patent/CS88091A2/cs unknown
- 1991-04-02 DK DK91907052.4T patent/DK0521994T3/da active
- 1991-04-02 SG SG1996000854A patent/SG54998A1/en unknown
- 1991-04-02 ES ES91907052T patent/ES2104697T3/es not_active Expired - Lifetime
- 1991-04-02 AU AU75842/91A patent/AU656134B2/en not_active Ceased
- 1991-04-02 DE DE69126609T patent/DE69126609T2/de not_active Revoked
- 1991-04-02 JP JP3506507A patent/JPH05505192A/ja active Pending
- 1991-04-02 AT AT91907052T patent/ATE154515T1/de not_active IP Right Cessation
- 1991-04-02 CA CA002079233A patent/CA2079233A1/en not_active Abandoned
- 1991-04-02 HU HU9330A patent/HUT63341A/hu unknown
- 1991-04-02 WO PCT/GB1991/000510 patent/WO1991014454A1/en not_active Ceased
- 1991-04-02 KR KR1019920070234A patent/KR100197915B1/ko not_active Expired - Lifetime
- 1991-04-02 EP EP91907052A patent/EP0521994B1/en not_active Revoked
- 1991-04-02 HK HK98103678A patent/HK1004531A1/en not_active IP Right Cessation
- 1991-04-02 RU SU5053188A patent/RU2104715C1/ru active
- 1991-04-03 NZ NZ237667A patent/NZ237667A/en unknown
-
1992
- 1992-09-28 NO NO923768A patent/NO923768D0/no unknown
- 1992-09-28 FI FI924340A patent/FI101043B/fi active
-
1994
- 1994-08-15 US US08/290,293 patent/US5665700A/en not_active Expired - Fee Related
-
1995
- 1995-06-30 HU HU95P/P00724P patent/HU211962A9/hu unknown
-
1997
- 1997-09-17 GR GR970402390T patent/GR3024745T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU7584291A (en) | 1991-10-21 |
| FI924340A0 (fi) | 1992-09-28 |
| NO923768L (no) | 1992-09-28 |
| CS88091A2 (en) | 1991-11-12 |
| FI924340L (fi) | 1992-09-28 |
| US5665700A (en) | 1997-09-09 |
| RU2104715C1 (ru) | 1998-02-20 |
| SG54998A1 (en) | 1998-12-21 |
| EP0521994A1 (en) | 1993-01-13 |
| PT97199B (pt) | 1998-07-31 |
| IE911086A1 (en) | 1991-10-09 |
| NZ237667A (en) | 1994-01-26 |
| ZA912411B (en) | 1992-11-25 |
| AU656134B2 (en) | 1995-01-27 |
| GB9007052D0 (en) | 1990-05-30 |
| NO923768D0 (no) | 1992-09-28 |
| JPH05505192A (ja) | 1993-08-05 |
| PT97199A (pt) | 1991-11-29 |
| HK1004531A1 (en) | 1998-11-27 |
| HUT63341A (en) | 1993-08-30 |
| HU9203093D0 (en) | 1992-12-28 |
| DE69126609D1 (de) | 1997-07-24 |
| KR100197915B1 (ko) | 1999-06-15 |
| FI101043B (fi) | 1998-04-15 |
| HU211962A9 (en) | 1996-01-29 |
| DK0521994T3 (da) | 1997-07-07 |
| WO1991014454A1 (en) | 1991-10-03 |
| CA2079233A1 (en) | 1991-09-30 |
| GR3024745T3 (en) | 1997-12-31 |
| DE69126609T2 (de) | 1998-01-02 |
| ATE154515T1 (de) | 1997-07-15 |
| EP0521994B1 (en) | 1997-06-18 |
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