ES2132190T3 - Complejo de ciclodextrina. - Google Patents

Complejo de ciclodextrina.

Info

Publication number
ES2132190T3
ES2132190T3 ES93305280T ES93305280T ES2132190T3 ES 2132190 T3 ES2132190 T3 ES 2132190T3 ES 93305280 T ES93305280 T ES 93305280T ES 93305280 T ES93305280 T ES 93305280T ES 2132190 T3 ES2132190 T3 ES 2132190T3
Authority
ES
Spain
Prior art keywords
cyclodextrin
pharmacy
water
polymer
elmar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93305280T
Other languages
English (en)
Inventor
Thorsteinn Loftsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cyclops hf
Original Assignee
Cyclops hf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyclops hf filed Critical Cyclops hf
Application granted granted Critical
Publication of ES2132190T3 publication Critical patent/ES2132190T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/559—Redox delivery systems, e.g. dihydropyridine pyridinium salt redox systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Dermatology (AREA)
  • Plant Pathology (AREA)
  • Birds (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medical Informatics (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Toxicology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION PROPORCIONA UN METODO PARA MEJORAR LOS DERIVADOS DE UNA CICLODEXTRINA CON UN FARMACO LIPOFILICO Y/O INESTABLE EN AGUA, COMPRENDIENDO LA COMBINACION DE 0''1 A 70% APROXIMADAMENTE (PESO/VOLUMEN) DE UNA CICLODEXTRINA Y DE 0''001 A 5% APROXIMADAMENTE (PESO/VOLUMEN) DE UN POLIMERO SOLUBLE EN AGUA, FARMACOLOGICAMENTE INACTIVO FARMACOLOGICAMENTE TOLERABLE, EN UN MEDIO ACUOSO DISOLVIENDOSE EN EL MEDIO ACUOSO EL POLIMERO Y LA CICLODEXTRINA, ANTES DE AÑADIR EL FARMACO, MANTENIENDOSE EL MEDIO ACUOSO QUE COMPRENDE AL POLIMERO Y A LA CICLODEXTRINA A UNA TEMPERATURA ENTRE 30 Y 150 C DURANTE UN PERIODO QUE OSCILA ENTRE 0''1 Y 100 HORAS ANTES, DURANTE Y/O DESPUES DE AÑADIR EL FARMACO, SEGUIDO OPCIONALMENTE POR LA EXTRACCION DEL AGUA. TAMBIEN SE FACILITAN METODOS AFINES, CO-COMPLEJOS DE FARMACO/CICLODEXTRINA/POLIMERO, COMPOSICIONES FARMACEUTICAS Y AGENTES Y SUSTANCIAS CAPACES DE FORMAR IONES COMPLEJOS, DE CICLODEXTRINA/POLIMERO. TAMBIEN SE DESCRIBEN METODOS ANALOGOS, COMPLEJOS Y COMPOSICIONES, ENLOS QUE EL FARMACO SE SUSTITUYE POR UN ADITIVO ALIMENTARIO, ADITIVO COSMETICO O AGROQUIMICO.
ES93305280T 1992-07-14 1993-07-06 Complejo de ciclodextrina. Expired - Lifetime ES2132190T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/912,853 US5324718A (en) 1992-07-14 1992-07-14 Cyclodextrin/drug complexation

Publications (1)

Publication Number Publication Date
ES2132190T3 true ES2132190T3 (es) 1999-08-16

Family

ID=25432562

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93305280T Expired - Lifetime ES2132190T3 (es) 1992-07-14 1993-07-06 Complejo de ciclodextrina.

Country Status (9)

Country Link
US (1) US5324718A (es)
EP (1) EP0579435B1 (es)
AT (1) ATE177647T1 (es)
DE (1) DE69323937T2 (es)
DK (1) DK0579435T3 (es)
ES (1) ES2132190T3 (es)
GR (1) GR3030345T3 (es)
IS (1) IS4049A (es)
SG (1) SG49182A1 (es)

Families Citing this family (151)

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DE69323937D1 (de) 1999-04-22
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US5324718A (en) 1994-06-28
ATE177647T1 (de) 1999-04-15
IS4049A (is) 1994-01-15
GR3030345T3 (en) 1999-09-30
EP0579435A1 (en) 1994-01-19
SG49182A1 (en) 1998-05-18
DE69323937T2 (de) 1999-09-23

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