ATE185605T1 - Nachweis von hepatits c mit verwendung rekombinanter antigene - Google Patents
Nachweis von hepatits c mit verwendung rekombinanter antigeneInfo
- Publication number
- ATE185605T1 ATE185605T1 AT91114161T AT91114161T ATE185605T1 AT E185605 T1 ATE185605 T1 AT E185605T1 AT 91114161 T AT91114161 T AT 91114161T AT 91114161 T AT91114161 T AT 91114161T AT E185605 T1 ATE185605 T1 AT E185605T1
- Authority
- AT
- Austria
- Prior art keywords
- assay
- recombinant antigens
- detection
- hcv
- hepatits
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 5
- 102000036639 antigens Human genes 0.000 title abstract 5
- 108091007433 antigens Proteins 0.000 title abstract 5
- 238000001514 detection method Methods 0.000 title abstract 2
- 241000711549 Hepacivirus C Species 0.000 abstract 4
- 238000003556 assay Methods 0.000 abstract 3
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 238000002820 assay format Methods 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000002809 confirmatory assay Methods 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 238000007423 screening assay Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57282290A | 1990-08-24 | 1990-08-24 | |
| US61406990A | 1990-11-07 | 1990-11-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE185605T1 true ATE185605T1 (de) | 1999-10-15 |
Family
ID=27075963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91114161T ATE185605T1 (de) | 1990-08-24 | 1991-08-23 | Nachweis von hepatits c mit verwendung rekombinanter antigene |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0472207B1 (de) |
| JP (1) | JP3354579B2 (de) |
| AT (1) | ATE185605T1 (de) |
| AU (1) | AU655592B2 (de) |
| CA (1) | CA2049679C (de) |
| DE (1) | DE69131707T2 (de) |
| ES (1) | ES2139571T3 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
| US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| AU650038B2 (en) * | 1988-03-11 | 1994-06-09 | Abbott Laboratories | CKS method of protein synthesis |
| US5308750A (en) * | 1989-12-22 | 1994-05-03 | Abbott Laboratories | Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same |
| US5582968A (en) * | 1990-02-16 | 1996-12-10 | United Biomedical, Inc. | Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis |
| US5712087A (en) * | 1990-04-04 | 1998-01-27 | Chiron Corporation | Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens |
| DE69225960T2 (de) * | 1991-01-31 | 1999-01-21 | Abbott Laboratories, Abbott Park, Ill. | Monoklonale antikörper gegen mögliche hcv-hüllregionen und methoden diese zu benutzen |
| KR0185426B1 (ko) * | 1991-06-24 | 1999-04-01 | 로버트 피. 블랙버언 | 씨형 간염 바이러스 폴리펩티드 |
| AU2501392A (en) * | 1991-08-21 | 1993-03-16 | Abbott Laboratories | Monoclonal antibodies to putative hcv ns5 proteins and methos for using same |
| JP3158177B2 (ja) * | 1991-10-08 | 2001-04-23 | 国立感染症研究所長 | C型肝炎診断薬 |
| JPH07503615A (ja) * | 1992-02-04 | 1995-04-20 | カイロン コーポレイション | 肝炎療剤 |
| GB9203803D0 (en) * | 1992-02-21 | 1992-04-08 | Wellcome Found | A recombinant polypeptide |
| JP2778886B2 (ja) * | 1992-10-16 | 1998-07-23 | エバーニュー バイオテック インコーポレイティド | C型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット |
| JPH06153959A (ja) * | 1992-10-16 | 1994-06-03 | Evernew Biotec Inc | C型肝炎ウィルスの非構造タンパク質及びそれを用いての診断方法及びキット |
| PT992580E (pt) * | 1993-11-04 | 2005-07-29 | Innogenetics Nv | Epitopos para celulas t humanas imunodominantes do virus da hepatite c |
| GB9513261D0 (en) * | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| US6329157B1 (en) | 1998-05-28 | 2001-12-11 | Abbott Laboratories | Antigen cocktails and uses thereof |
| CA2333598C (en) * | 1998-05-28 | 2009-10-13 | Abbott Laboratories | Toxoplasma gondii antigens, p35, and uses thereof |
| SK287694B6 (sk) | 2000-06-15 | 2011-06-06 | Novartis Vaccines & Diagnostics, Inc. | Pevný nosič imunoeseje a spôsob jeho prípravy, spôsob detekcie infekcie HIV a súprava na imunodiagnostickú skúšku |
| US7166426B2 (en) | 2002-09-09 | 2007-01-23 | Novartis Vaccines And Diagnostics, Inc. | HCV assay |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0253193B1 (de) * | 1986-07-08 | 1992-10-28 | Abbott Laboratories | Verfahren für die Mutagenese durch eine oligonukleotidgeleitete Reparatur eines Strangbruchs |
| BR8807310A (pt) * | 1987-11-18 | 1990-03-13 | Chiron Corp | Polinucleotidio,polinucleotidio recombinante,vetor recombinante,celula hospedeira,sistema de expressao recombinante,celula transformada,polipeptidio,hcv,preparacao de polipeptidio,polipeptidio de hcv,polipeptidio purificado,polipeptidio recombinante,polipeptidio de fusao,anticorpo monoclonal,preparacao purificada de anticorpos policlonais,particula,sonda de polinucleotidio,kit anticorpo para epetopo de hcv,metodo para producao de polipeptidio,metodo para deteccao de acidos nucleicos de hcv,imunoensaio para detectar antigeno de hcv,imunoensaio para detectar anticorpos dirigidos contra antigeno de hcv,vacina para tratamento de infeccao de hcv,celula,celula infectada com hcv,metodo para producao de anticorpos para hcv e metodo para isolar cdna derivado do genoma de um agente infeccioso nao identificado |
| US5124255A (en) * | 1988-03-11 | 1992-06-23 | Abbott Laboratories | CKS method of protein synthesis |
| US5075077A (en) * | 1988-08-02 | 1991-12-24 | Abbott Laboratories | Test card for performing assays |
| HU225068B1 (en) * | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
| AU638304B2 (en) * | 1989-12-22 | 1993-06-24 | Abbott Laboratories | Hepatitis c assay |
| KR940000755B1 (ko) * | 1990-02-16 | 1994-01-29 | 유나이티드 바이오메디칼 인코오포레이티드 | Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드 |
| WO1991015771A1 (en) * | 1990-04-04 | 1991-10-17 | Chiron Corporation | Combinations of hepatitis c virus (hcv) antigens for use in immunoassays for anti-hcv antibodies |
| CA2047792C (en) * | 1990-07-26 | 2002-07-02 | Chang Y. Wang | Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines |
| DE4209215A1 (de) * | 1991-07-04 | 1993-01-07 | Boehringer Mannheim Gmbh | Hcv peptidantigene und verfahren zur bestimmung von hcv |
| EP0525910A1 (de) * | 1991-08-02 | 1993-02-03 | Akzo Nobel N.V. | Non-A, non-B Peptid |
| ZA927837B (en) * | 1991-10-15 | 1994-03-11 | Akzo Nv | Monoclonal antibodiesto hepatitis C virus |
-
1991
- 1991-08-22 CA CA002049679A patent/CA2049679C/en not_active Expired - Lifetime
- 1991-08-23 AT AT91114161T patent/ATE185605T1/de not_active IP Right Cessation
- 1991-08-23 EP EP91114161A patent/EP0472207B1/de not_active Expired - Lifetime
- 1991-08-23 DE DE69131707T patent/DE69131707T2/de not_active Expired - Lifetime
- 1991-08-23 AU AU82774/91A patent/AU655592B2/en not_active Ceased
- 1991-08-23 ES ES91114161T patent/ES2139571T3/es not_active Expired - Lifetime
- 1991-08-26 JP JP24058791A patent/JP3354579B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU8277491A (en) | 1992-05-07 |
| EP0472207A2 (de) | 1992-02-26 |
| DE69131707T2 (de) | 2000-06-08 |
| EP0472207B1 (de) | 1999-10-13 |
| ES2139571T3 (es) | 2000-02-16 |
| JPH04281792A (ja) | 1992-10-07 |
| CA2049679A1 (en) | 1992-02-25 |
| JP3354579B2 (ja) | 2002-12-09 |
| DE69131707D1 (de) | 1999-11-18 |
| EP0472207A3 (en) | 1992-08-26 |
| AU655592B2 (en) | 1995-01-05 |
| CA2049679C (en) | 2005-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |