ATE185605T1 - Nachweis von hepatits c mit verwendung rekombinanter antigene - Google Patents

Nachweis von hepatits c mit verwendung rekombinanter antigene

Info

Publication number
ATE185605T1
ATE185605T1 AT91114161T AT91114161T ATE185605T1 AT E185605 T1 ATE185605 T1 AT E185605T1 AT 91114161 T AT91114161 T AT 91114161T AT 91114161 T AT91114161 T AT 91114161T AT E185605 T1 ATE185605 T1 AT E185605T1
Authority
AT
Austria
Prior art keywords
assay
recombinant antigens
detection
hcv
hepatits
Prior art date
Application number
AT91114161T
Other languages
English (en)
Inventor
Sushil G Devare
Suresh M Desai
James M Casey
George J Dawson
Richard R Lesniewski
Stephen H Dailey
Robin A Gutierrez
James Lawrence Stewart
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27075963&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE185605(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE185605T1 publication Critical patent/ATE185605T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT91114161T 1990-08-24 1991-08-23 Nachweis von hepatits c mit verwendung rekombinanter antigene ATE185605T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57282290A 1990-08-24 1990-08-24
US61406990A 1990-11-07 1990-11-07

Publications (1)

Publication Number Publication Date
ATE185605T1 true ATE185605T1 (de) 1999-10-15

Family

ID=27075963

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91114161T ATE185605T1 (de) 1990-08-24 1991-08-23 Nachweis von hepatits c mit verwendung rekombinanter antigene

Country Status (7)

Country Link
EP (1) EP0472207B1 (de)
JP (1) JP3354579B2 (de)
AT (1) ATE185605T1 (de)
AU (1) AU655592B2 (de)
CA (1) CA2049679C (de)
DE (1) DE69131707T2 (de)
ES (1) ES2139571T3 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
AU650038B2 (en) * 1988-03-11 1994-06-09 Abbott Laboratories CKS method of protein synthesis
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
US5582968A (en) * 1990-02-16 1996-12-10 United Biomedical, Inc. Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis
US5712087A (en) * 1990-04-04 1998-01-27 Chiron Corporation Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens
ATE167522T1 (de) * 1991-01-31 1998-07-15 Abbott Lab Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen
ES2188583T3 (es) 1991-06-24 2003-07-01 Chiron Corp Polipeptidos para el virus de la hepatitis c (hcv).
DE69227776T2 (de) * 1991-08-21 1999-07-01 Abbott Laboratories, Abbott Park, Ill. Monoklonale antikörper gegen mutmassliche hepatitis c-virus ns5-proteine und ihre anwendungsmethoden
JP3158177B2 (ja) * 1991-10-08 2001-04-23 国立感染症研究所長 Ｃ型肝炎診断薬
DK0625204T3 (da) * 1992-02-04 2002-07-15 Chiron Corp Terapeutiske midler mod hepatitis
GB9203803D0 (en) * 1992-02-21 1992-04-08 Wellcome Found A recombinant polypeptide
JP2778886B2 (ja) * 1992-10-16 1998-07-23 エバーニュー バイオテック インコーポレイティド Ｃ型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット
JPH06153959A (ja) * 1992-10-16 1994-06-03 Evernew Biotec Inc Ｃ型肝炎ウィルスの非構造タンパク質及びそれを用いての診断方法及びキット
ATE236981T1 (de) * 1993-11-04 2003-04-15 Innogenetics Nv Von menschlichen t-zellen immunodominante epiropen des virus der c-hepatitis
GB9513261D0 (en) * 1995-06-29 1995-09-06 Smithkline Beecham Biolog Vaccines
US6329157B1 (en) 1998-05-28 2001-12-11 Abbott Laboratories Antigen cocktails and uses thereof
EP1082343A2 (de) * 1998-05-28 2001-03-14 Abbott Laboratories Antigene von toxoplasma gondii, p35, und ihre verwendungen
SI1354204T2 (sl) 2000-06-15 2010-09-30 Novartis Vaccines & Diagnostic Hcv antigen antitelo kombinacijska analiza
ES2312806T3 (es) 2002-09-09 2009-03-01 Novartis Vaccines And Diagnostics, Inc. Ensayo de vhc.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253193B1 (de) * 1986-07-08 1992-10-28 Abbott Laboratories Verfahren für die Mutagenese durch eine oligonukleotidgeleitete Reparatur eines Strangbruchs
JPH02500880A (ja) * 1987-11-18 1990-03-29 カイロン　コーポレイション Ｎａｎｂｖの診断用薬およびワクチン
US5124255A (en) * 1988-03-11 1992-06-23 Abbott Laboratories CKS method of protein synthesis
US5075077A (en) * 1988-08-02 1991-12-24 Abbott Laboratories Test card for performing assays
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
CA2032907C (en) * 1989-12-22 2002-05-14 Richard R. Lesniewski Hepatitis c assay
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
HU217025B (hu) * 1990-04-04 1999-11-29 Chiron Corp. Hepatitis C vírus-(HCV) antigénkészítmények az anti-HCV-antitestek kimutatására immunoassay-kben
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
DE4209215A1 (de) * 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
FI923448L (fi) * 1991-08-02 1993-02-03 Akzo Nv Non-a, non-b-peptid
ZA927837B (en) * 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus

Also Published As

Publication number Publication date
EP0472207B1 (de) 1999-10-13
AU8277491A (en) 1992-05-07
CA2049679C (en) 2005-06-21
DE69131707T2 (de) 2000-06-08
CA2049679A1 (en) 1992-02-25
EP0472207A3 (en) 1992-08-26
JP3354579B2 (ja) 2002-12-09
AU655592B2 (en) 1995-01-05
DE69131707D1 (de) 1999-11-18
ES2139571T3 (es) 2000-02-16
EP0472207A2 (de) 1992-02-26
JPH04281792A (ja) 1992-10-07

Similar Documents

Publication Publication Date Title
DE69131707D1 (de) Nachweis von Hepatits C mit Verwendung rekombinanter Antigene
EP0445423A3 (en) Hepatitis c assay
GR940300008T1 (de)
DK1354204T3 (da) HCV-antigen/antistof-kombinationssay
NO870412D0 (no) Peptider.
ATE191792T1 (de) Verfahren zur detektion von hepatitis c
DE69133599D1 (de) Enterisch übertragendes non-a/non-b-hepatitis-virus agens und charakteristische epitope von selbigem
DE69230812D1 (de) Verfahren zum Nachweis einer Rinderdiarrhoe- virusinfektion, für ein durch eine Infektion mit diesem Virus induziertes Eiweiss kodierende Nukleotidsequenz, sowie daraus abgeleitete rekombinante Eiweisse und Antigene
DE3579856D1 (de) Immunulogischer test zur bestimmung von gemeinsamen, bestimmenden hepatitis-b-antikoerpern.
KR880014376A (ko) Hiv 특이 항원 영역의 모노클로날 항체 및 그 용법
CA2116026A1 (en) Hepatitis c assay utilizing recombinant antigens to c-100 region
ES2156858T3 (es) Reactivo de diagnostico para hepatitis c.
ATE143142T1 (de) Immunoassay zum nachweis von antikörpern gegen hiv
AP9901515A0 (en) Reagent system and kit or detecting HIV infected cells.
KR930703613A (ko) 시료 희석물중 과산화물 디스뮤타제의 용도
RU2370776C2 (ru) Набор антигенов для раздельного выявления антител к структурным и неструктурным белкам вируса гепатита с
Ireland Development of enzyme-linked immunosorbent assays for antibodies to hepatitis B virus.
Werner et al. Prevalence of serological markers for viral hepatitis and AIDS in rural Punjab
KR950704353A (ko) 씨(c)형 간염 비루스(hcv) 비-구조-3 펩티드, 그에 대한 항체 및 에이취씨브이(hcv)의 검출 방법(hepatitis c virus(hcv) non-structurac-3 peptides, antibodies thereto and methods for the detection of hcv)
BR0206887A (pt) Reagentes para a detecção simult nea de antìgenos e anticorpos de núcleo de do vìrus da hepatite c (hcv)
Tang et al. Detection of measles virus specific IgM antibody with ELISA.
UA36086A (uk) Тест-система для підтвердження наявності антитіл проти вірусу гепатиту с (іфа-п-hcv)
EP0365172A3 (de) Nachweis von anti-pre-S-Antikörpern

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee