ES2155197T3 - Poblaciones de celulas quiescentes para transferencia nuclear. - Google Patents

Poblaciones de celulas quiescentes para transferencia nuclear.

Info

Publication number
ES2155197T3
ES2155197T3 ES96928587T ES96928587T ES2155197T3 ES 2155197 T3 ES2155197 T3 ES 2155197T3 ES 96928587 T ES96928587 T ES 96928587T ES 96928587 T ES96928587 T ES 96928587T ES 2155197 T3 ES2155197 T3 ES 2155197T3
Authority
ES
Spain
Prior art keywords
cell
nuclear transfer
quescent
cell populations
transgenic animals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96928587T
Other languages
English (en)
Inventor
Keith Henry Stockman Campbell
Ian Wilmut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Minister of Agriculture Fisheries and Food UK
Biotechnology and Biological Sciences Research Council
Roslin Institute
Original Assignee
Minister of Agriculture Fisheries and Food UK
Biotechnology and Biological Sciences Research Council
Roslin Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minister of Agriculture Fisheries and Food UK, Biotechnology and Biological Sciences Research Council, Roslin Institute filed Critical Minister of Agriculture Fisheries and Food UK
Application granted granted Critical
Publication of ES2155197T3 publication Critical patent/ES2155197T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8771—Bovine embryos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C12N15/8773—Ovine embryos

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Reproductive Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA RECONSTITUIR UN EMBRION DE ANIMAL QUE IMPLICA TRANSFERIR EL NUCLEO DESDE UNA CELULA DONANTE QUIESCENTE HACIA EL INTERIOR DE UNA CELULA RECEPTORA ADECUADA. LA CELULA DONANTE ES QUIESCENTE, ES DECIR, SE PROVOCA QUE SALGA DEL CICLO DE CRECIMIENTO Y DIVISION EN G1, Y QUE SE DETENGA EN EL ESTADO G0. LA TRANSFERENCIA NUCLEAR PUEDE TENER LUGAR MEDIANTE FUSION CELULAR. EL EMBRION RECONSTITUIDO PUEDE ENTONCES PRODUCIR UNO O MAS ANIMALES. LA INVENCION RESULTA UTIL EN LA PRODUCCION DE ANIMALES TRANSGENICOS, ASI COMO DE ANIMALES NO TRANSGENICOS CON ELEVADAS VENTAJAS GENETICAS.
ES96928587T 1995-08-31 1996-08-30 Poblaciones de celulas quiescentes para transferencia nuclear. Expired - Lifetime ES2155197T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9517780.4A GB9517780D0 (en) 1995-08-31 1995-08-31 Biological manipulation

Publications (1)

Publication Number Publication Date
ES2155197T3 true ES2155197T3 (es) 2001-05-01

Family

ID=10779998

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96928587T Expired - Lifetime ES2155197T3 (es) 1995-08-31 1996-08-30 Poblaciones de celulas quiescentes para transferencia nuclear.

Country Status (23)

Country Link
US (5) US6147276A (es)
EP (3) EP0849990B1 (es)
JP (2) JP4081613B2 (es)
KR (4) KR100533476B1 (es)
CN (3) CN1769431A (es)
AT (1) ATE199115T1 (es)
AU (1) AU716956C (es)
BR (1) BR9610034B1 (es)
CA (1) CA2229568C (es)
CZ (1) CZ60898A3 (es)
DE (1) DE69611793T2 (es)
DK (1) DK0849990T3 (es)
ES (1) ES2155197T3 (es)
GB (2) GB9517780D0 (es)
HU (1) HUP9900234A3 (es)
IL (1) IL123298A0 (es)
NO (1) NO980845L (es)
NZ (3) NZ316149A (es)
PL (1) PL325331A1 (es)
SG (1) SG75155A1 (es)
SI (1) SI0849990T1 (es)
WO (1) WO1997007669A1 (es)
ZA (1) ZA967390B (es)

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* Cited by examiner, † Cited by third party
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