ES2156851T3 - Amplificacion de adn de genomas multiples para detectar deleciones. - Google Patents

Amplificacion de adn de genomas multiples para detectar deleciones.

Info

Publication number
ES2156851T3
ES2156851T3 ES89310424T ES89310424T ES2156851T3 ES 2156851 T3 ES2156851 T3 ES 2156851T3 ES 89310424 T ES89310424 T ES 89310424T ES 89310424 T ES89310424 T ES 89310424T ES 2156851 T3 ES2156851 T3 ES 2156851T3
Authority
ES
Spain
Prior art keywords
amplification
sequences
genome dna
complimentary
annealing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89310424T
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English (en)
Other versions
ES2156851T5 (es
Inventor
Charles T Caskey
Jeffrey S Chamberlain
Richard A L Gibbs
Joel E Rainer
Phi Nga Nguyen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baylor College of Medicine
Original Assignee
Baylor College of Medicine
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Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22973199&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2156851(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baylor College of Medicine filed Critical Baylor College of Medicine
Publication of ES2156851T3 publication Critical patent/ES2156851T3/es
Application granted granted Critical
Publication of ES2156851T5 publication Critical patent/ES2156851T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4707—Muscular dystrophy
    • C07K14/4708—Duchenne dystrophy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

EL INVENTO SE REFIERE A UN METODO PARA DETECTAR SIMULTANEAMENTE MULTIPLES SECUENCIAS DE DNA. EL METODO COMPRENDE LA AMPLIFICACION DE FRECUENCIAS MULTIPLES SIMULTANEAMENTE DESCOMPONIENDO UNA PLURALIDAD DE OLEGONUCLEOITIDOS PRIMARIOS PAREADOS EN DNA DE RAMAL SIMPLE. UN MIEMBRO DE CADA PAR ES COMPLEMENTARIO EN EL SENTIDO DEL RAMAL DE UNA SECUENCIAS Y EL OTRO MIEMBRO ES COMPLEMENTARIO A UN SEGMENTO DIFERENTE DEL RAMAL CONTRARIO DE LA MISMA SECUENCIA. LA AMPLIFICACION SE PRODUCE ALTERNATIVAMENTE DESCOMPONIENDO Y EXTENDIENDO LOS PRIMARIOS. EL INVENTO TAMBIEN INCLUYE SECUENCIAS PRIMARIAS DE OLIGONUCLEOTIDOS UTILES EN LA DETECCION DE ENFERMEDADES GENETICAS Y / O SECUENCIAS DE DNA EXOGENAS.
ES89310424T 1988-10-12 1989-10-11 Amplificacion del adn de genomas multiples para la deteccion de supresiones. Expired - Lifetime ES2156851T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25668988A 1988-10-12 1988-10-12
US256689 1988-10-12

Publications (2)

Publication Number Publication Date
ES2156851T3 true ES2156851T3 (es) 2001-08-01
ES2156851T5 ES2156851T5 (es) 2009-06-23

Family

ID=22973199

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89310424T Expired - Lifetime ES2156851T5 (es) 1988-10-12 1989-10-11 Amplificacion del adn de genomas multiples para la deteccion de supresiones.

Country Status (9)

Country Link
US (1) US5582989A (es)
EP (1) EP0364255B2 (es)
JP (1) JPH07136000A (es)
KR (1) KR900006520A (es)
AT (1) ATE201451T1 (es)
AU (2) AU634175B2 (es)
CA (1) CA1339731C (es)
DE (1) DE68929299T3 (es)
ES (1) ES2156851T5 (es)

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CA1339731C (en) 1998-03-17
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DE68929299D1 (de) 2001-06-28
EP0364255B2 (en) 2008-12-31
AU4260589A (en) 1990-04-26
ATE201451T1 (de) 2001-06-15
ES2156851T5 (es) 2009-06-23
DE68929299T3 (de) 2009-07-09
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DE68929299T2 (de) 2001-12-06
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