ES2159683T3 - Formulacion transdermica de un compuesto con actividad muscarinica. - Google Patents

Formulacion transdermica de un compuesto con actividad muscarinica.

Info

Publication number
ES2159683T3
ES2159683T3 ES96300710T ES96300710T ES2159683T3 ES 2159683 T3 ES2159683 T3 ES 2159683T3 ES 96300710 T ES96300710 T ES 96300710T ES 96300710 T ES96300710 T ES 96300710T ES 2159683 T3 ES2159683 T3 ES 2159683T3
Authority
ES
Spain
Prior art keywords
transdermic
formulation
compound
muscarinic activity
muscarinic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96300710T
Other languages
English (en)
Inventor
Franklin P Bymaster
Harlan E Shannon
Lisa A Shipley
Kirti H Valia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2159683T3 publication Critical patent/ES2159683T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA INVENCION SUMINISTRA UN METODO PARA TRATAR UNA CONDICION ASOCIADA CON LA MODULACION DEL RECEPTOR MUSCARINICO QUE UTILIZA UNA FORMACION TRANSDERMICA DE 3-[4-(BUTILTIO)-1,2,5-TIADIAZOL-3IL]-1-AZABICICLO-[2.2.2]OCTANO. LA INVENCION SUMINISTRA FORMULACIONES DE PARCHES TRANSDERMICOS DE 3-[4-(BUTILTIO)-1,2,5TIADIAZOL-3-IL]-1-AZABICICLO[2.2.2]OCTANO.
ES96300710T 1995-02-17 1996-02-01 Formulacion transdermica de un compuesto con actividad muscarinica. Expired - Lifetime ES2159683T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39044595A 1995-02-17 1995-02-17
US48101695A 1995-06-07 1995-06-07

Publications (1)

Publication Number Publication Date
ES2159683T3 true ES2159683T3 (es) 2001-10-16

Family

ID=27013141

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96300710T Expired - Lifetime ES2159683T3 (es) 1995-02-17 1996-02-01 Formulacion transdermica de un compuesto con actividad muscarinica.

Country Status (22)

Country Link
US (1) US5858393A (es)
EP (1) EP0727208B1 (es)
JP (1) JPH11505513A (es)
KR (1) KR19980702239A (es)
CN (1) CN1181007A (es)
AR (1) AR002027A1 (es)
AU (1) AU700023B2 (es)
BR (1) BR9607722A (es)
CA (1) CA2212874A1 (es)
CO (1) CO4700408A1 (es)
CZ (1) CZ255097A3 (es)
DE (1) DE69614419T2 (es)
ES (1) ES2159683T3 (es)
FI (1) FI973362A7 (es)
HU (1) HUP9802070A3 (es)
IL (1) IL116997A0 (es)
NO (1) NO973715L (es)
NZ (1) NZ302147A (es)
PE (1) PE17897A1 (es)
TR (1) TR199700799T1 (es)
WO (1) WO1996025154A1 (es)
YU (1) YU6196A (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528529B1 (en) 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
US6417227B1 (en) 1999-04-28 2002-07-09 Cg And Associates Methods of delivery of cetyl myristoleate
WO2001030316A2 (en) * 1999-10-28 2001-05-03 3M Innovative Properties Company Transdermal drug delivery devices comprising (r)-(z)-1-azabicyclo(2.2.1)heptan-3-one, 0-(3(3-methoxyphenyl)-2-propynyl)oxime
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
US20070264130A1 (en) * 2006-01-27 2007-11-15 Phluid, Inc. Infusion Pumps and Methods for Use
US8986253B2 (en) * 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
WO2009143188A2 (en) * 2008-05-19 2009-11-26 Diperna Paul M Disposable pump reservoir and related methods
US7943187B2 (en) * 2008-05-23 2011-05-17 Bakr Rabie Paeoniflorin preparations and uses thereof for fat reduction
EP2363116A1 (en) 2008-06-25 2011-09-07 US Worldmeds LLC Sustained-release formulations comprising lofexidine for oral delivery
US8408421B2 (en) * 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
CA2737461A1 (en) * 2008-09-19 2010-03-25 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
EP2724739B1 (en) * 2009-07-30 2015-07-01 Tandem Diabetes Care, Inc. Portable infusion pump system
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US12567493B2 (en) 2021-10-12 2026-03-03 Tandem Diabetes Care, Inc. Systems and methods for delayed meal boluses in automated insulin delivery

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
IT1233860B (it) * 1988-02-08 1992-04-21 Isf Spa Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5238933A (en) * 1991-10-28 1993-08-24 Sri International Skin permeation enhancer compositions
KR960703908A (ko) * 1993-08-19 1996-08-31 안네 세커 정신병 치료방법(Antipsychotic method)

Also Published As

Publication number Publication date
CA2212874A1 (en) 1996-08-22
DE69614419D1 (de) 2001-09-20
CO4700408A1 (es) 1998-12-29
CN1181007A (zh) 1998-05-06
DE69614419T2 (de) 2002-05-23
HUP9802070A3 (en) 2000-09-28
TR199700799T1 (xx) 1998-02-21
FI973362A0 (fi) 1997-08-15
AR002027A1 (es) 1998-01-07
IL116997A0 (en) 1996-06-18
BR9607722A (pt) 1998-07-14
MX9706143A (es) 1997-11-29
CZ255097A3 (en) 1997-12-17
JPH11505513A (ja) 1999-05-21
US5858393A (en) 1999-01-12
NO973715D0 (no) 1997-08-12
EP0727208B1 (en) 2001-08-16
NZ302147A (en) 1998-10-28
EP0727208A1 (en) 1996-08-21
PE17897A1 (es) 1997-06-12
AU4774296A (en) 1996-09-04
WO1996025154A1 (en) 1996-08-22
KR19980702239A (ko) 1998-07-15
HUP9802070A2 (hu) 1999-02-01
NO973715L (no) 1997-08-12
YU6196A (sh) 1998-09-18
FI973362L (fi) 1997-08-15
AU700023B2 (en) 1998-12-17
FI973362A7 (fi) 1997-08-15

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