ES2172827T3 - Nuevos derivados de la eritromicina, su procedimiento de preparacion y su empleo como medicamento. - Google Patents
Nuevos derivados de la eritromicina, su procedimiento de preparacion y su empleo como medicamento.Info
- Publication number
- ES2172827T3 ES2172827T3 ES97952973T ES97952973T ES2172827T3 ES 2172827 T3 ES2172827 T3 ES 2172827T3 ES 97952973 T ES97952973 T ES 97952973T ES 97952973 T ES97952973 T ES 97952973T ES 2172827 T3 ES2172827 T3 ES 2172827T3
- Authority
- ES
- Spain
- Prior art keywords
- erythromycin
- employment
- preparation procedure
- medicinal product
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA (I) EN LOS CUALES X RESPRESENTA UN GRUPO CH 2 O NH, R REPRESENTA UN RADICAL (CH 2 ) N AR, N=CH(CH 2 ) N AR, EN EL QUE N REPRESENTA UN NUMERO ENTERO COMPRENDIDO ENTRE 1 A 6 Y AR REPRESENTA UN RADICAL ARILO O HETEROARILO OPCIONALMENTE SUSTITUIDO, LAS LINEAS DISCONITUNUAS REPRESENTAN UN ENLACE DOBLE OPCIONAL EN 2(3), E Y REPRESENTA UN ATOMO DE HIDROGENO O EL RESTO DE UN ACIDO ORGANICO CARBOXILICO QUE CONTIENE HASTA 18 ATOMOS DE CARBONO ASI COMO SUS SALES DE ADICION CON LOS ACIDOS. LOS COMPUESTOS DE FORMULA (I) PRESENTAN INTERESANTES PROPIEDADES ANTIBIOTICAS QUE PERMITEN SU UTILIZACION COMO MEDICAMENTOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9615830A FR2757518B1 (fr) | 1996-12-23 | 1996-12-23 | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2172827T3 true ES2172827T3 (es) | 2002-10-01 |
Family
ID=9498984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97952973T Expired - Lifetime ES2172827T3 (es) | 1996-12-23 | 1997-12-22 | Nuevos derivados de la eritromicina, su procedimiento de preparacion y su empleo como medicamento. |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0946580B1 (es) |
| JP (2) | JP4522496B2 (es) |
| KR (1) | KR20000062286A (es) |
| CN (1) | CN1246123A (es) |
| AP (1) | AP9901566A0 (es) |
| AT (1) | ATE215553T1 (es) |
| AU (1) | AU726147B2 (es) |
| BR (1) | BR9713618A (es) |
| CA (1) | CA2275359A1 (es) |
| CZ (1) | CZ293732B6 (es) |
| DE (1) | DE69711689T2 (es) |
| DK (1) | DK0946580T3 (es) |
| EA (1) | EA199900589A1 (es) |
| ES (1) | ES2172827T3 (es) |
| FR (1) | FR2757518B1 (es) |
| HU (1) | HUP0001452A3 (es) |
| ID (1) | ID21883A (es) |
| IL (1) | IL130510A0 (es) |
| NO (1) | NO993124L (es) |
| PL (1) | PL334134A1 (es) |
| PT (1) | PT946580E (es) |
| SK (1) | SK83199A3 (es) |
| TR (1) | TR199901452T2 (es) |
| WO (1) | WO1998028316A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2757518B1 (fr) * | 1996-12-23 | 1999-06-11 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| YU44900A (sh) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola |
| US6720308B1 (en) * | 2002-11-07 | 2004-04-13 | Enanta Pharmaceuticals, Inc. | Anhydrolide derivatives having antibacterial activity |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99995A (en) * | 1990-11-21 | 1997-11-20 | Roussel Uclaf | Erythromycin derivatives, their preparation and pharmaceutical compositions containing them |
| JPH0853355A (ja) * | 1994-08-12 | 1996-02-27 | Taisho Pharmaceut Co Ltd | Ｉｌ−５産生抑制剤 |
| JP2000501077A (ja) * | 1995-11-08 | 2000-02-02 | アボツト・ラボラトリーズ | エリスロマイシンａおよびｂの３−デオキシ−３−デスクラジノース誘導体 |
| DE69723848T2 (de) * | 1996-05-07 | 2004-07-01 | Abbott Laboratories, Abbott Park | 3-descladinose-2,3-anhydroerythromycin-derivate |
| FR2757518B1 (fr) * | 1996-12-23 | 1999-06-11 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
-
1996
- 1996-12-23 FR FR9615830A patent/FR2757518B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-22 AT AT97952973T patent/ATE215553T1/de not_active IP Right Cessation
- 1997-12-22 KR KR1019997005682A patent/KR20000062286A/ko not_active Withdrawn
- 1997-12-22 DE DE69711689T patent/DE69711689T2/de not_active Expired - Lifetime
- 1997-12-22 ES ES97952973T patent/ES2172827T3/es not_active Expired - Lifetime
- 1997-12-22 PL PL97334134A patent/PL334134A1/xx unknown
- 1997-12-22 CA CA002275359A patent/CA2275359A1/fr not_active Abandoned
- 1997-12-22 TR TR1999/01452T patent/TR199901452T2/xx unknown
- 1997-12-22 AU AU56679/98A patent/AU726147B2/en not_active Ceased
- 1997-12-22 PT PT97952973T patent/PT946580E/pt unknown
- 1997-12-22 DK DK97952973T patent/DK0946580T3/da active
- 1997-12-22 ID IDW990572A patent/ID21883A/id unknown
- 1997-12-22 CN CN97181784A patent/CN1246123A/zh active Pending
- 1997-12-22 AP APAP/P/1999/001566A patent/AP9901566A0/en unknown
- 1997-12-22 HU HU0001452A patent/HUP0001452A3/hu unknown
- 1997-12-22 IL IL13051097A patent/IL130510A0/xx unknown
- 1997-12-22 SK SK831-99A patent/SK83199A3/sk unknown
- 1997-12-22 EA EA199900589A patent/EA199900589A1/ru unknown
- 1997-12-22 EP EP97952973A patent/EP0946580B1/fr not_active Expired - Lifetime
- 1997-12-22 JP JP52847498A patent/JP4522496B2/ja not_active Expired - Lifetime
- 1997-12-22 WO PCT/FR1997/002380 patent/WO1998028316A1/fr not_active Ceased
- 1997-12-22 CZ CZ19992279A patent/CZ293732B6/cs not_active IP Right Cessation
- 1997-12-22 BR BR9713618-2A patent/BR9713618A/pt not_active Application Discontinuation
-
1999
- 1999-06-23 NO NO993124A patent/NO993124L/no not_active Application Discontinuation
-
2010
- 2010-02-01 JP JP2010020522A patent/JP5188520B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PL334134A1 (en) | 2000-02-14 |
| PT946580E (pt) | 2002-09-30 |
| JP5188520B2 (ja) | 2013-04-24 |
| JP4522496B2 (ja) | 2010-08-11 |
| ATE215553T1 (de) | 2002-04-15 |
| KR20000062286A (ko) | 2000-10-25 |
| BR9713618A (pt) | 2000-04-11 |
| DK0946580T3 (da) | 2002-07-22 |
| FR2757518A1 (fr) | 1998-06-26 |
| AU5667998A (en) | 1998-07-17 |
| CZ293732B6 (cs) | 2004-07-14 |
| EP0946580B1 (fr) | 2002-04-03 |
| DE69711689D1 (de) | 2002-05-08 |
| JP2001507011A (ja) | 2001-05-29 |
| CA2275359A1 (fr) | 1998-07-02 |
| NO993124D0 (no) | 1999-06-23 |
| NO993124L (no) | 1999-08-20 |
| JP2010132683A (ja) | 2010-06-17 |
| ID21883A (id) | 1999-08-05 |
| FR2757518B1 (fr) | 1999-06-11 |
| HU0001452B (hu) | 2000-09-28 |
| SK83199A3 (en) | 2000-05-16 |
| DE69711689T2 (de) | 2002-10-17 |
| HUP0001452A3 (en) | 2000-10-30 |
| AP9901566A0 (en) | 1999-06-30 |
| CZ227999A3 (cs) | 1999-10-13 |
| TR199901452T2 (xx) | 1999-10-21 |
| EP0946580A1 (fr) | 1999-10-06 |
| IL130510A0 (en) | 2000-06-01 |
| CN1246123A (zh) | 2000-03-01 |
| AU726147B2 (en) | 2000-11-02 |
| WO1998028316A1 (fr) | 1998-07-02 |
| EA199900589A1 (ru) | 2000-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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