ES2174296T3 - Preparacion oral, que contiene en una matriz capaz de hincharse en medio acuoso, al menos un principio activo farmaceutico. - Google Patents

Preparacion oral, que contiene en una matriz capaz de hincharse en medio acuoso, al menos un principio activo farmaceutico.

Info

Publication number
ES2174296T3
ES2174296T3 ES97944810T ES97944810T ES2174296T3 ES 2174296 T3 ES2174296 T3 ES 2174296T3 ES 97944810 T ES97944810 T ES 97944810T ES 97944810 T ES97944810 T ES 97944810T ES 2174296 T3 ES2174296 T3 ES 2174296T3
Authority
ES
Spain
Prior art keywords
matrix
layer
active principle
pharmaceutical active
oral preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97944810T
Other languages
English (en)
Inventor
Karsten Cremer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Application granted granted Critical
Publication of ES2174296T3 publication Critical patent/ES2174296T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

UNA PREPARACION ORAL, QUE CONTIENE EN UNA MATRIZ QUE SE PUEDE HINCHAR EN MEDIO ACUOSO AL MENOS UN PRINCIPIO ACTIVO FARMACEUTICO, QUE SE LIBERA DE MANERA RETARDADA EN EL MEDIO ACUOSO CUANDO LA MATRIZ SE HINCHA, SIENDO LA MATRIZ MUY RESISTENTE A LA DESCOMPOSICION DURANTE EL PROCESO DE LIBERACION, SE CARACTERIZA PORQUE CONTIENE UNA TABLETA ESTRATIFICADA CON CAPAS PEGADAS UNAS A LAS OTRAS, DE LAS CUALES AL MENOS UNA CAPA ES LA CAPA DE LA MATRIZ HINCHABLE, Y AL MENOS OTRA CAPA ES UNA CAPA DE ADITIVO Y/O SOPORTE, Y QUE LA CAPA DE MATRIZ HINCHABLE TIENE UNA PARTE DE AMILOSA RETICULADA DE MANERA TRANSVERSAL.
ES97944810T 1996-09-28 1997-08-29 Preparacion oral, que contiene en una matriz capaz de hincharse en medio acuoso, al menos un principio activo farmaceutico. Expired - Lifetime ES2174296T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19640062A DE19640062B4 (de) 1996-09-28 1996-09-28 Orale Zubereitung, enthaltend in einer in wässrigem Medium quellbaren Matrix wenigstens einen pharmazeutischen Wirkstoff

Publications (1)

Publication Number Publication Date
ES2174296T3 true ES2174296T3 (es) 2002-11-01

Family

ID=7807265

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97944810T Expired - Lifetime ES2174296T3 (es) 1996-09-28 1997-08-29 Preparacion oral, que contiene en una matriz capaz de hincharse en medio acuoso, al menos un principio activo farmaceutico.

Country Status (23)

Country Link
US (1) US6238698B1 (es)
EP (1) EP0946150B1 (es)
JP (1) JP2001504807A (es)
KR (1) KR100493139B1 (es)
CN (1) CN1139378C (es)
AT (1) ATE213933T1 (es)
AU (1) AU724802B2 (es)
CA (1) CA2260845C (es)
CZ (1) CZ291258B6 (es)
DE (2) DE19640062B4 (es)
DK (1) DK0946150T3 (es)
ES (1) ES2174296T3 (es)
HU (1) HU227865B1 (es)
IL (1) IL129171A (es)
MY (1) MY130959A (es)
NO (1) NO991477L (es)
NZ (1) NZ333401A (es)
PL (1) PL188392B1 (es)
PT (1) PT946150E (es)
SI (1) SI0946150T1 (es)
SK (1) SK282709B6 (es)
WO (1) WO1998013028A1 (es)
ZA (1) ZA978625B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US8487002B2 (en) 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
CA2491665A1 (fr) * 2004-12-24 2006-06-24 Louis Cartilier Formulation de comprime pour liberation soutenue de principe actif
RU2008113439A (ru) 2005-09-09 2009-10-20 Лабофарм Инк. (CA) Композиции с замедленным высвобождением лекарственного средства
EA014739B1 (ru) 2005-09-09 2011-02-28 Лабофарм Инк. Композиция тразодона для введения один раз в день
US20080286343A1 (en) * 2007-05-16 2008-11-20 Dzenana Cengic Solid form
US8226967B2 (en) 2008-11-27 2012-07-24 Basf Se Surface active proteins as excipients in solid pharmaceutical formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1237904B (it) 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
US5603956A (en) * 1990-11-27 1997-02-18 Labopharm Inc. Cross-linked enzymatically controlled drug release
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
HU221591B (hu) 1992-07-24 2002-11-28 Labopharm Inc. Keresztkötéses polihidroxil-származék enzimatikusan szabályozott hatóanyag-kibocsátáshoz
US5616343A (en) * 1993-03-25 1997-04-01 Labopharm, Inc. Cross-linked amylose as a binder/disintegrant in tablets
DE4341442C2 (de) 1993-12-04 1998-11-05 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung
DE4416926C2 (de) 1994-05-13 2000-01-13 Lohmann Therapie Syst Lts Verfahren zur Herstellung von Vorrichtungen zur kontrollierten Freisetzung von Wirkstoffen
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
EP1984443B1 (en) 2006-02-14 2014-04-02 The Procter and Gamble Company Personal care compositions comprising responsive particles

Also Published As

Publication number Publication date
SI0946150T1 (en) 2002-08-31
CA2260845C (en) 2005-11-22
HUP9903115A2 (hu) 2000-02-28
CN1139378C (zh) 2004-02-25
ZA978625B (en) 1998-03-26
HU227865B1 (en) 2012-05-29
WO1998013028A1 (de) 1998-04-02
IL129171A (en) 2001-11-25
CZ291258B6 (cs) 2003-01-15
PL188392B1 (pl) 2005-01-31
CZ101399A3 (cs) 1999-07-14
US6238698B1 (en) 2001-05-29
DE19640062B4 (de) 2006-04-27
NZ333401A (en) 1999-10-28
PL332577A1 (en) 1999-09-27
KR100493139B1 (ko) 2005-06-02
EP0946150A1 (de) 1999-10-06
MY130959A (en) 2007-07-31
ATE213933T1 (de) 2002-03-15
NO991477D0 (no) 1999-03-26
EP0946150B1 (de) 2002-03-06
HUP9903115A3 (en) 2000-03-28
PT946150E (pt) 2002-08-30
NO991477L (no) 1999-03-26
SK282709B6 (sk) 2002-11-06
DE19640062A1 (de) 1998-04-09
JP2001504807A (ja) 2001-04-10
IL129171A0 (en) 2000-02-17
SK38799A3 (en) 2000-03-13
DE59706576D1 (de) 2002-04-11
CN1231600A (zh) 1999-10-13
CA2260845A1 (en) 1998-04-02
DK0946150T3 (da) 2002-06-24
AU724802B2 (en) 2000-09-28
AU4619397A (en) 1998-04-17
KR20010029533A (ko) 2001-04-06

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