ES2182351T3 - Composicion farmaceutica en aerosol. - Google Patents

Composicion farmaceutica en aerosol.

Info

Publication number
ES2182351T3
ES2182351T3 ES98937474T ES98937474T ES2182351T3 ES 2182351 T3 ES2182351 T3 ES 2182351T3 ES 98937474 T ES98937474 T ES 98937474T ES 98937474 T ES98937474 T ES 98937474T ES 2182351 T3 ES2182351 T3 ES 2182351T3
Authority
ES
Spain
Prior art keywords
aerosol
damm
inhaler
pharmaceutical composition
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98937474T
Other languages
English (en)
Other versions
ES2182351T5 (es
Inventor
David Lewis
Davis Ganderton
Brian Meakin
Paolo Ventura
Gaetano Brambilla
Raffaella Garzia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10814179&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2182351(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Application granted granted Critical
Publication of ES2182351T3 publication Critical patent/ES2182351T3/es
Publication of ES2182351T5 publication Critical patent/ES2182351T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE EXPONE UNA COMPOSICION PARA USO EN UN INHALADOR DE AEROSOL, QUE COMPRENDE UN MATERIAL ACTIVO, UN PROPULSANTE QUE CONTIENE UN HIDROFLUORALCANO Y UN CO-DISOLVENTE. LA COMPOSICION INCLUYE ADEMAS UN COMPONENTE DE ESCASA VOLATILIDAD, QUE SE AÑADE A FIN DE AUMENTAR EL DIAMETRO AERODINAMICO MEDIANO DE LA MASA (DAMM) DE LAS PARTICULAS DE AEROSOL, CUANDO SE ACCIONA EL INHALADOR. GRACIAS A LA ADICCION DEL COMPONENTE DE BAJA VOLATILIDAD, EL DAMM DE LAS PARTICULAS DE AEROSOL PUEDE SER COMPARABLE CON EL DAMM DE PARTICULAS DE AEROSOL DE UN INHALADOR DE ESTE TIPO QUE INCLUYE CFC COMO PROPULSOR.
ES98937474T 1997-06-13 1998-06-10 Composicion farmaceutica en aerosol. Expired - Lifetime ES2182351T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9712434A GB2326334A (en) 1997-06-13 1997-06-13 Pharmaceutical aerosol compositions
GB9712434 1997-06-13

Publications (2)

Publication Number Publication Date
ES2182351T3 true ES2182351T3 (es) 2003-03-01
ES2182351T5 ES2182351T5 (es) 2007-03-16

Family

ID=10814179

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98937474T Expired - Lifetime ES2182351T5 (es) 1997-06-13 1998-06-10 Composicion farmaceutica en aerosol.

Country Status (44)

Country Link
EP (2) EP0920302B2 (es)
JP (1) JP4380802B2 (es)
KR (1) KR100546239B1 (es)
CN (1) CN1138532C (es)
AR (1) AR012977A1 (es)
AT (1) ATE222751T1 (es)
AU (1) AU729966B2 (es)
BG (1) BG63906B1 (es)
BR (1) BR9805993B1 (es)
CA (1) CA2263445C (es)
CO (1) CO4940408A1 (es)
CZ (1) CZ295521B6 (es)
DE (1) DE69807420T3 (es)
DK (1) DK0920302T4 (es)
DZ (1) DZ2516A1 (es)
EA (1) EA001259B1 (es)
EE (1) EE03664B1 (es)
ES (1) ES2182351T5 (es)
GB (1) GB2326334A (es)
GE (1) GEP20012462B (es)
HR (1) HRP980317B1 (es)
HU (1) HU228487B1 (es)
ID (1) ID21491A (es)
IL (1) IL128484A (es)
IN (1) IN189317B (es)
IS (1) IS2435B (es)
IT (1) IT1293803B1 (es)
MA (1) MA26507A1 (es)
ME (2) MEP44008A (es)
MY (1) MY119074A (es)
NO (1) NO327775B1 (es)
NZ (1) NZ334149A (es)
PL (1) PL193721B1 (es)
PT (1) PT920302E (es)
RS (1) RS51274B (es)
SA (1) SA98190821B1 (es)
SI (1) SI0920302T2 (es)
SK (1) SK284430B8 (es)
TN (1) TNSN98087A1 (es)
TR (1) TR199900288T1 (es)
TW (1) TW555570B (es)
UA (1) UA70289C2 (es)
WO (1) WO1998056349A1 (es)
ZA (1) ZA985136B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
CA2317999C (en) 1999-09-11 2004-11-09 Glaxo Group Limited Pharmaceutical formulation of fluticasone propionate
EP1523976A3 (en) * 1999-11-23 2005-06-22 Glaxo Group Limited Pharmaceutical formulations of salmeterol
EP1248597B1 (en) * 1999-12-24 2005-03-30 Glaxo Group Limited Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
JP5392880B2 (ja) 2000-05-22 2014-01-22 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 加圧式定量吸入器のための安定な製薬学的溶液製剤
AU2002238748A1 (en) * 2001-03-12 2002-09-24 Glaxo Group Limited Pharmaceutical aerosol formulation
DE60103527T2 (de) 2001-07-02 2005-06-16 Chiesi Farmaceutici S.P.A. Optimierte Tobramycin-Formulierung zur Aerosolbildung
EP1340492A1 (en) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Aerosol formulations for pulmonary administration of medicaments having systemic effects
IL163843A0 (en) 2002-03-01 2005-12-18 Chiesi Farma Spa Formoterol superfine formulation
EP1340503A1 (en) * 2002-03-01 2003-09-03 CHIESI FARMACEUTICI S.p.A. Solution aerosol formulation containing esters of 3, 17-dihydroxy oestratriene derivates for pulmonary delivery
DE10214263A1 (de) * 2002-03-28 2003-10-16 Boehringer Ingelheim Pharma HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum
EP1369113B1 (en) * 2002-06-06 2006-11-22 CHIESI FARMACEUTICI S.p.A. Solubilisation of drugs in HFA propellant by means of emulsions
WO2004071488A1 (en) * 2003-02-04 2004-08-26 Chrysalis Technologies Incorporated Perfluorocarbon and hydrofluorocarbon formulations and methods of making and using same
EP1915985A1 (en) * 2003-03-20 2008-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Formulation for a Metered Dose Inhaler Using Hydro-Fluoro-Alkanes as Propellants
ME00420B (me) * 2003-03-20 2011-12-20 Boehringer Ingelheim Pharmaceuticals Inc Formulacija, za inhalator u kojem se odmjerava doza, u kojoj se kao propelenti koriste hidro-fluoro-alkani
SE0303179D0 (sv) * 2003-11-26 2003-11-26 Astrazeneca Ab Novel compounds
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
BRPI0512878A (pt) 2004-07-02 2008-04-15 Boehringer Ingelheim Int formulações de suspensão de aerossol, com tg 227 ea ou tg 134 a como agente propulsor
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
GB0621707D0 (en) * 2006-10-31 2006-12-13 Univ London Pharmacy Formulations for delivery via pressurised metered dose inhalers
GB0712454D0 (en) 2007-06-27 2007-08-08 Generics Uk Ltd Pharmaceutical compositions
US20110105449A1 (en) * 2007-11-07 2011-05-05 Astrazeneca R&D Dry powder formulations comprising ascorbic acid derivates
CN105854136A (zh) * 2010-09-06 2016-08-17 奇斯药制品公司 计量剂量吸入器和使用该计量剂量吸入器的方法
JP5409594B2 (ja) * 2010-12-22 2014-02-05 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 加圧式定量吸入器のための安定な製薬学的溶液製剤
EP2819669B1 (de) 2012-02-28 2021-04-21 Boehringer Ingelheim International GmbH Neue treibgashaltige tiotropium-formulierung
RU2504402C1 (ru) * 2012-11-20 2014-01-20 Шолекс Девелопмент Гмбх Ингаляционный состав в форме аэрозоля для лечения бронхиальной астмы и хронической обструктивной болезни легких
GB201402513D0 (en) 2014-02-13 2014-04-02 Cardiff Scintigraphics Ltd Pressurised metered dose inhalers and method of manufacture
EP3174522A1 (en) 2014-07-29 2017-06-07 3M Innovative Properties Company Method of preparing a pharmaceutical composition
WO2017167737A1 (en) 2016-03-31 2017-10-05 Chiesi Farmaceutici S.P.A. Aerosol inhalation device
AU2017328908B2 (en) * 2016-09-19 2020-04-02 Mexichem Fluor S.A. De C.V. Pharmaceutical composition
WO2025039045A1 (en) * 2023-08-23 2025-02-27 Inhaler Supplies Pty Ltd Inhalable formulation for volatile actives

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU597049B2 (en) † 1986-03-10 1990-05-24 Kurt Burghart Pharmaceutical preparation containing nifedipine
WO1987005210A1 (fr) † 1986-03-10 1987-09-11 Kurt Burghart Produit pharmaceutique et son procede de preparation
US4899874A (en) † 1988-04-26 1990-02-13 Rehrig-Pacific Company, Inc. Stackable low depth bottle case
US5225183A (en) † 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
DE3905726A1 (de) * 1989-02-24 1990-08-30 Hoechst Ag Druckgaspackung und treibmittel fuer aerosole
AU658854B2 (en) † 1990-10-18 1995-05-04 Minnesota Mining And Manufacturing Company Aerosol formulation comprising beclomethasone 17,21 dipropionate
GB9024365D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
DK1277467T3 (da) † 1991-06-10 2007-01-15 Schering Corp Formuleringer af ikke-chlorfluorcarbonaerosoler
ES2200771T3 (es) † 1991-06-10 2004-03-16 Schering Corporation Formulaciones en aerosol no clorofluorocarbonadas.
DE4123663A1 (de) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Aerosol-zubereitung und verwendung eines treibmittels dafuer
DE4123668A1 (de) * 1991-07-17 1993-01-21 Rovema Gmbh Verfahren und vorrichtung zur zufuehrung von folienmaterial zu einer intermittierend arbeitenden schlauchbeutelmaschine
ATE128350T1 (de) * 1991-12-12 1995-10-15 Glaxo Group Ltd Pharmazeutische aerosolformulierung.
DK0617610T3 (da) * 1991-12-18 1997-10-06 Minnesota Mining & Mfg Suspensionsaerosolformuleringer.
EP0673240B1 (en) * 1992-12-09 1999-03-24 Boehringer Ingelheim Pharmaceuticals Inc. Stabilized medicinal aerosol solution formulations
US5502076A (en) * 1994-03-08 1996-03-26 Hoffmann-La Roche Inc. Dispersing agents for use with hydrofluoroalkane propellants
US5508023A (en) * 1994-04-11 1996-04-16 The Center For Innovative Technology Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
US5534242A (en) † 1994-05-02 1996-07-09 Henry; Richard A. Lidocaine-vasoconstrictor aerosol preparation
JP3911290B2 (ja) † 1994-05-13 2007-05-09 アラダイム コーポレーション エアゾールを含む麻酔用処方
US5653961A (en) † 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
US5635161A (en) † 1995-06-07 1997-06-03 Abbott Laboratories Aerosol drug formulations containing vegetable oils
GB9517998D0 (en) † 1995-09-04 1995-11-08 Bioglan Lab Ltd Compositions and device for their administration
EP0914143A1 (en) * 1996-07-08 1999-05-12 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation
JP2001505171A (ja) † 1996-12-04 2001-04-17 バイオグラン アイルランド（アール アンド ディ）リミテッド 製薬組成物及びその投与のための装置
DK1014943T3 (da) † 1997-02-05 2002-10-14 Jago Res Ag Medicinske aerosolformuleringer

Also Published As

Publication number Publication date
TW555570B (en) 2003-10-01
EP1219293A3 (en) 2003-05-28
EA199900201A1 (ru) 1999-06-24
BR9805993B1 (pt) 2009-05-05
EP0920302B2 (en) 2006-06-21
YU6999A (sh) 2000-03-21
SI0920302T2 (sl) 2006-10-31
ES2182351T5 (es) 2007-03-16
ZA985136B (en) 1999-01-07
IL128484A (en) 2004-09-27
SK284430B8 (sk) 2005-05-05
CN1138532C (zh) 2004-02-18
HRP980317A2 (en) 1999-04-30
DE69807420T3 (de) 2006-11-16
EP0920302B1 (en) 2002-08-28
DE69807420T2 (de) 2003-05-08
HRP980317B1 (en) 2002-06-30
ID21491A (id) 1999-06-17
CZ46299A3 (cs) 1999-07-14
CN1229355A (zh) 1999-09-22
PT920302E (pt) 2002-11-29
AU729966B2 (en) 2001-02-15
MEP44008A (hr) 2011-02-10
CZ295521B6 (cs) 2005-08-17
IS4974A (is) 1999-02-11
DE69807420D1 (de) 2002-10-02
CA2263445A1 (en) 1998-12-17
JP2000516965A (ja) 2000-12-19
DZ2516A1 (fr) 2004-11-08
AR012977A1 (es) 2000-11-22
GB2326334A (en) 1998-12-23
TR199900288T1 (xx) 1999-09-21
KR100546239B1 (ko) 2006-01-26
NO990594D0 (no) 1999-02-09
NZ334149A (en) 2000-07-28
BG103221A (bg) 1999-09-30
PL193721B1 (pl) 2007-03-30
MA26507A1 (fr) 2004-12-20
SK17699A3 (en) 1999-07-12
SI0920302T1 (sl) 2002-12-31
AU8626298A (en) 1998-12-30
ME00333B (me) 2011-02-10
DK0920302T4 (da) 2006-10-09
NO990594L (no) 1999-04-13
SK284430B6 (sk) 2005-04-01
HK1022271A1 (en) 2000-08-04
EP1219293A2 (en) 2002-07-03
CA2263445C (en) 2008-09-09
TNSN98087A1 (fr) 2005-03-15
GEP20012462B (en) 2001-06-25
IS2435B (is) 2008-10-15
GB9712434D0 (en) 1997-08-13
JP4380802B2 (ja) 2009-12-09
DK0920302T3 (da) 2002-12-23
IL128484A0 (en) 2000-01-31
SA98190821B1 (ar) 2006-11-19
HUP0001339A2 (hu) 2000-09-28
EA001259B1 (ru) 2000-12-25
BR9805993A (pt) 1999-08-31
MY119074A (en) 2005-03-31
ATE222751T1 (de) 2002-09-15
IN189317B (es) 2003-02-08
PL331531A1 (en) 1999-07-19
HUP0001339A3 (en) 2000-10-30
RS51274B (sr) 2010-12-31
EE9900055A (et) 1999-08-16
EE03664B1 (et) 2002-04-15
UA70289C2 (uk) 2004-10-15
HU228487B1 (en) 2013-03-28
EP0920302A1 (en) 1999-06-09
IT1293803B1 (it) 1999-03-10
CO4940408A1 (es) 2000-07-24
WO1998056349A1 (en) 1998-12-17
ITMI971798A1 (it) 1999-01-28
NO327775B1 (no) 2009-09-21
KR20000068171A (ko) 2000-11-25
BG63906B1 (bg) 2003-06-30

Similar Documents

Publication Publication Date Title
BR9805993A (pt) Composição farmacêutica de aerosol.
AR029523A1 (es) Formulaciones farmaceuticas en solucion estable para inhaladores presurizados con medicion de dosis
FI964285A0 (fi) Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet
TR200101442T2 (tr) HFA 227 ve HFA 137 ihtiva eden farmasötik aeorosol bileşimi
AR072123A1 (es) Composiciones que contienen un agente activo solvatado adecuadas para ser dispensadas como un aerosol de gas comprimido
ECSP056029A (es) Formulación para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores
PA8575701A1 (es) Preparaciones acidas de insulina con estabilidad mejorada
ES2052029T3 (es) Composiciones pulverizables para el cabello que contienen silicona.
BR0316310A (pt) Composições farmacêuticas tendo um veìculo modificado
AR057697A1 (es) Composiciones de pulverizacion
AR022483A1 (es) Composicion detergente
AR012621A1 (es) Composiciones organicas
AR033325A1 (es) Composicion que comprende una carnitina y glutationa , util para incrementar la absorcion de la glutationa y sinergizar sus efectos, un complemento dietario, medicamento, la utilizacion de una composicion de combinacion para preparar un complemento dietario o un medicamento
BRPI0413957A (pt) processo para preparar diterpenos solúveis em água, solução aquosa e suas aplicações
GT200600307A (es) Formas de dosificacion de liberacion retardada oral altamente biodisponibles de succinato de o-desmetilvenlafaxina
JPS5325284A (en) Aerosol composition
RU2008117429A (ru) Композиция для обработки волос
TR199900379T2 (xx) Klorofluorokarbon i�ermeyen mometazon furoat aerosol form�lasyonlar�.
ES2159563T3 (es) Composicion de limpieza de hornos no caustica a baja temperatura.
AR023582A1 (es) Polinucleotidos de npr1 de maiz y metodos de uso de los mismos
BR112023015690A2 (pt) Material gerador de aerossol, grânulo de tabaco, consumível, sistema de fornecimento de aerossol não combustível e uso de um agente de expansão
BRPI0406666A (pt) Aglutinante de eletrodo aquoso e eletrodos e células de combustìvel incluindo o mesmo
JPS5545626A (en) Poultice
GR1002731B (el) Φαρμακευτικα ενεσιμα διαλυματα περιεχοντα συνδυασμους παρακεταμολης με αλλες δραστικες ουσιες.
AR018360A1 (es) Una composicion para el tratamiento del cabello y su uso