ES2317116T3 - Derivados de carbonilos sustituidos heterociclicos y su uso como ligandos del receptor de dopamina d3. - Google Patents

Derivados de carbonilos sustituidos heterociclicos y su uso como ligandos del receptor de dopamina d3. Download PDF

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Publication number
ES2317116T3
ES2317116T3 ES05018120T ES05018120T ES2317116T3 ES 2317116 T3 ES2317116 T3 ES 2317116T3 ES 05018120 T ES05018120 T ES 05018120T ES 05018120 T ES05018120 T ES 05018120T ES 2317116 T3 ES2317116 T3 ES 2317116T3
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Prior art keywords
disorders
dopamine
compounds
receptors
disease
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ES05018120T
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Inventor
James A. Hendrix
Horst Hemmerle
Matthias Urmann
Gregory M. Shutske
Joseph T. Strupczewski
Kenneth J. Bordeau
John G. Jurcak
Thaddeus Nieduzak
Sharon Anne Jackson
Paul Angell
James P. Carey
George E. Lee
David M. Fink
Jean-Francois Sabuco
Yulin Chiang
Nicola Collar
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Aventis Pharmaceuticals Inc
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Aventis Pharmaceuticals Inc
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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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Abstract

Un compuesto de fórmula (I): ** ver fórmula** dibde A es CH O N; n es 1 y es 0; g es 1 ó 2 cada R 3 es independientemente hidrógeno, alquilo C 1-C 6,
ES05018120T 2001-02-16 2002-02-15 Derivados de carbonilos sustituidos heterociclicos y su uso como ligandos del receptor de dopamina d3. Expired - Lifetime ES2317116T3 (es)

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US26967201P 2001-02-16 2001-02-16
US269672P 2001-02-16
GBGB0117577.7A GB0117577D0 (en) 2001-02-16 2001-07-19 Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D receptor ligands
GB0117577 2001-07-19

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AU2002250107B2 (en) 2008-05-29
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WO2002066446A1 (en) 2002-08-29
ATE313534T1 (de) 2006-01-15
EP1632483A1 (en) 2006-03-08
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EP1362039B1 (en) 2005-12-21
EP1632483B1 (en) 2008-10-29
EP1935887A1 (en) 2008-06-25
DE60208157T2 (de) 2006-08-10
PT1632483E (pt) 2009-01-12
DE60208157D1 (de) 2006-01-26
JP2009185055A (ja) 2009-08-20
ES2253526T3 (es) 2006-06-01

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