ATE455108T1 - Heterocyclische substituierte carbonyl derivate und ihre verwendung als dopamin d3 rezeptor liganden - Google Patents

Heterocyclische substituierte carbonyl derivate und ihre verwendung als dopamin d3 rezeptor liganden

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Publication number
ATE455108T1
ATE455108T1 AT08004461T AT08004461T ATE455108T1 AT E455108 T1 ATE455108 T1 AT E455108T1 AT 08004461 T AT08004461 T AT 08004461T AT 08004461 T AT08004461 T AT 08004461T AT E455108 T1 ATE455108 T1 AT E455108T1
Authority
AT
Austria
Prior art keywords
disorders
dopamine
compounds
substituted carbonyl
heterocyclic substituted
Prior art date
Application number
AT08004461T
Other languages
English (en)
Inventor
James A Hendrix
Horst Hemmerle
Matthias Urmann
Gregory M Shutske
Joseph T Strupczewski
Kenneth K Bordeau
John G Jurcak
Thaddeus Nieduzak
Sharon Anne Jackson
Paul Angell
James P Carey
George E Lee
David M Fink
Jean-Francois Sabuco
Yulin Chiang
Nicola Collar
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0117577.7A external-priority patent/GB0117577D0/en
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of ATE455108T1 publication Critical patent/ATE455108T1/de

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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

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AT08004461T 2001-02-16 2002-02-15 Heterocyclische substituierte carbonyl derivate und ihre verwendung als dopamin d3 rezeptor liganden ATE455108T1 (de)

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ES2317116T3 (es) 2009-04-16
WO2002066446A1 (en) 2002-08-29
ATE313534T1 (de) 2006-01-15
EP1632483A1 (de) 2006-03-08
EP1362039A1 (de) 2003-11-19
EP1362039B1 (de) 2005-12-21
EP1632483B1 (de) 2008-10-29
EP1935887A1 (de) 2008-06-25
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