ES2381025T3 - Inmunocitocinas con selectividad modulada - Google Patents

Inmunocitocinas con selectividad modulada Download PDF

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Publication number
ES2381025T3
ES2381025T3 ES02792325T ES02792325T ES2381025T3 ES 2381025 T3 ES2381025 T3 ES 2381025T3 ES 02792325 T ES02792325 T ES 02792325T ES 02792325 T ES02792325 T ES 02792325T ES 2381025 T3 ES2381025 T3 ES 2381025T3
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ES
Spain
Prior art keywords
fusion protein
ala
huks
fraction
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02792325T
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English (en)
Spanish (es)
Inventor
Stephen D. Gillies
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Merck Patent GmbH
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Merck Patent GmbH
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Publication date
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Publication of ES2381025T3 publication Critical patent/ES2381025T3/es
Anticipated expiration legal-status Critical
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES02792325T 2001-12-04 2002-12-04 Inmunocitocinas con selectividad modulada Expired - Lifetime ES2381025T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33711301P 2001-12-04 2001-12-04
US337113P 2001-12-04
US37196602P 2002-04-12 2002-04-12
US371966P 2002-04-12
PCT/US2002/038780 WO2003048334A2 (fr) 2001-12-04 2002-12-04 Immunocytokines a selectivite modulee

Publications (1)

Publication Number Publication Date
ES2381025T3 true ES2381025T3 (es) 2012-05-22

Family

ID=26990541

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02792325T Expired - Lifetime ES2381025T3 (es) 2001-12-04 2002-12-04 Inmunocitocinas con selectividad modulada

Country Status (18)

Country Link
US (3) US7186804B2 (fr)
EP (2) EP1454138B1 (fr)
JP (1) JP4795640B2 (fr)
KR (1) KR100988180B1 (fr)
CN (1) CN100390282C (fr)
AT (1) ATE542137T1 (fr)
AU (1) AU2002357784B2 (fr)
BR (1) BR0214650A (fr)
CA (1) CA2469151C (fr)
DK (1) DK1454138T3 (fr)
ES (1) ES2381025T3 (fr)
HU (1) HU229098B1 (fr)
MX (1) MXPA04005266A (fr)
PL (1) PL206975B1 (fr)
PT (1) PT1454138E (fr)
RU (1) RU2312677C9 (fr)
WO (1) WO2003048334A2 (fr)
ZA (1) ZA200405247B (fr)

Families Citing this family (184)

* Cited by examiner, † Cited by third party
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PT1454138E (pt) 2012-03-28
RU2312677C9 (ru) 2008-03-27
US20070036752A1 (en) 2007-02-15
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WO2003048334A2 (fr) 2003-06-12
HU229098B1 (hu) 2013-07-29
AU2002357784A1 (en) 2003-06-17
RU2312677C2 (ru) 2007-12-20
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KR20050044862A (ko) 2005-05-13
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CN100390282C (zh) 2008-05-28
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ATE542137T1 (de) 2012-02-15
US7888071B2 (en) 2011-02-15
US20090098609A1 (en) 2009-04-16
EP2354791A1 (fr) 2011-08-10
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