ES338710A2 - A procedure for preparing tetracycline derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for preparing tetracycline derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES338710A2 ES338710A2 ES338710A ES338710A ES338710A2 ES 338710 A2 ES338710 A2 ES 338710A2 ES 338710 A ES338710 A ES 338710A ES 338710 A ES338710 A ES 338710A ES 338710 A2 ES338710 A2 ES 338710A2
- Authority
- ES
- Spain
- Prior art keywords
- translation
- formula
- machine
- legally binding
- google translate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000004098 Tetracycline Substances 0.000 title abstract 3
- 229960002180 tetracycline Drugs 0.000 title abstract 3
- 229930101283 tetracycline Natural products 0.000 title abstract 2
- 235000019364 tetracycline Nutrition 0.000 title abstract 2
- 150000003522 tetracyclines Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Improvements made to the object of main patent no. 277,406, issued September 20, 1962, for "A process for preparing tetracycline derivatives" for a process for preparing 7-amino substituted-tetracycline compounds of formula: **(See formula)** where R6 is hydrogen or methyl, and R7 is mono- (lower alcohol) -amino or di (lower alcohol) -amino; characterized by contacting a compound of the formula: **(See formula)** where X is bromine, chlorine or fluorine, R6 is hydrogen or methyl, and R is aryl, with a carbonyl compound of the formula: **(See formula)** where R1 and R2 are the same or different, and are hydrogen or lower alcohol, in the presence of a reducing agent. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14713761A | 1961-10-24 | 1961-10-24 | |
| US161412A US3148212A (en) | 1961-12-22 | 1961-12-22 | Reductive alkylation process |
| US17159962A | 1962-02-07 | 1962-02-07 | |
| ES277406A ES277406A1 (en) | 1961-10-24 | 1962-05-17 | A procedure for preparing tetracycline derivatives (Machine-translation by Google Translate, not legally binding) |
| US53928266A | 1966-04-01 | 1966-04-01 | |
| US54436866A | 1966-04-22 | 1966-04-22 | |
| US58920666A | 1966-10-25 | 1966-10-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES338710A2 true ES338710A2 (en) | 1968-04-01 |
Family
ID=56089740
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES277406A Expired ES277406A1 (en) | 1961-10-24 | 1962-05-17 | A procedure for preparing tetracycline derivatives (Machine-translation by Google Translate, not legally binding) |
| ES338710A Expired ES338710A2 (en) | 1961-10-24 | 1967-03-31 | A procedure for preparing tetracycline derivatives. (Machine-translation by Google Translate, not legally binding) |
| ES379444A Expired ES379444A2 (en) | 1961-10-24 | 1970-05-08 | A procedure for preparing tetracycline derivatives (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES277406A Expired ES277406A1 (en) | 1961-10-24 | 1962-05-17 | A procedure for preparing tetracycline derivatives (Machine-translation by Google Translate, not legally binding) |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES379444A Expired ES379444A2 (en) | 1961-10-24 | 1970-05-08 | A procedure for preparing tetracycline derivatives (Machine-translation by Google Translate, not legally binding) |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE618065A (en) |
| CH (2) | CH448070A (en) |
| DK (1) | DK126586B (en) |
| ES (3) | ES277406A1 (en) |
| GB (1) | GB1003474A (en) |
| LU (1) | LU41768A1 (en) |
| MC (1) | MC370A1 (en) |
| SE (1) | SE309416B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
-
1962
- 1962-05-16 MC MC389A patent/MC370A1/en unknown
- 1962-05-17 ES ES277406A patent/ES277406A1/en not_active Expired
- 1962-05-17 GB GB19034/62A patent/GB1003474A/en not_active Expired
- 1962-05-22 CH CH1577466A patent/CH448070A/en unknown
- 1962-05-22 CH CH618162A patent/CH444848A/en unknown
- 1962-05-24 BE BE618065A patent/BE618065A/en unknown
- 1962-05-24 LU LU41768D patent/LU41768A1/xx unknown
- 1962-05-24 DK DK235062AA patent/DK126586B/en unknown
-
1963
- 1963-11-22 SE SE12945/63A patent/SE309416B/xx unknown
-
1967
- 1967-03-31 ES ES338710A patent/ES338710A2/en not_active Expired
-
1970
- 1970-05-08 ES ES379444A patent/ES379444A2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1003474A (en) | 1965-09-02 |
| CH444848A (en) | 1967-10-15 |
| BE618065A (en) | 1962-11-26 |
| CH448070A (en) | 1967-12-15 |
| LU41768A1 (en) | 1962-07-24 |
| ES379444A2 (en) | 1972-11-01 |
| SE309416B (en) | 1969-03-24 |
| DK126586B (en) | 1973-07-30 |
| ES277406A1 (en) | 1962-12-01 |
| MC370A1 (en) | 1963-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170629 |