ES542902A0 - Procedimiento para la obtencion de derivados de benzotiace- pina - Google Patents
Procedimiento para la obtencion de derivados de benzotiace- pinaInfo
- Publication number
- ES542902A0 ES542902A0 ES542902A ES542902A ES542902A0 ES 542902 A0 ES542902 A0 ES 542902A0 ES 542902 A ES542902 A ES 542902A ES 542902 A ES542902 A ES 542902A ES 542902 A0 ES542902 A0 ES 542902A0
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- advantageously
- hydrocarbon solvent
- aliphatic
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 5
- 235000007119 Ananas comosus Nutrition 0.000 title 1
- 244000099147 Ananas comosus Species 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 4
- 239000004215 Carbon black (E152) Substances 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229930195733 hydrocarbon Natural products 0.000 abstract 3
- 150000002430 hydrocarbons Chemical class 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 abstract 2
- 229910001863 barium hydroxide Inorganic materials 0.000 abstract 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 abstract 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 abstract 2
- 239000000920 calcium hydroxide Substances 0.000 abstract 2
- -1 quaternary ammonium halide Chemical class 0.000 abstract 2
- FHGWEHGZBUBQKL-UHFFFAOYSA-N 1,2-benzothiazepine Chemical class S1N=CC=CC2=CC=CC=C12 FHGWEHGZBUBQKL-UHFFFAOYSA-N 0.000 abstract 1
- WQMAANNAZKNUDL-UHFFFAOYSA-N 2-dimethylaminoethyl chloride Chemical compound CN(C)CCCl WQMAANNAZKNUDL-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002051 biphasic effect Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL71538A IL71538A (en) | 1984-04-13 | 1984-04-13 | Process for the preparation of benzothiazepine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8603704A1 ES8603704A1 (es) | 1986-01-01 |
| ES542902A0 true ES542902A0 (es) | 1986-01-01 |
Family
ID=11054990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES542902A Granted ES542902A0 (es) | 1984-04-13 | 1985-04-12 | Procedimiento para la obtencion de derivados de benzotiace- pina |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4566995A (es) |
| EP (1) | EP0158303B1 (es) |
| JP (1) | JPH06768B2 (es) |
| AT (1) | ATE65083T1 (es) |
| CA (1) | CA1223585A (es) |
| DE (1) | DE3583407D1 (es) |
| ES (1) | ES542902A0 (es) |
| IL (1) | IL71538A (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4652561A (en) * | 1986-02-26 | 1987-03-24 | Hoffmann-La Roche Inc. | Naphtho[1,2-b]-1,4-thiazepinones |
| IL81954A0 (en) * | 1986-03-24 | 1987-10-20 | Hoffmann La Roche | Naphthothiazocinones,their manufacture and pharmaceutical compositions containing them |
| US4808580A (en) * | 1987-12-17 | 1989-02-28 | Hoffmann-La Roche Inc. | Naphtho[1,2-b][1,4]thiazepin-4(5H)-ones and use thereof in treatment of ischemia and blood pressure lowering |
| IT1244878B (it) * | 1990-12-11 | 1994-09-12 | Lusochimica Spa | Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato |
| TW438787B (en) | 1997-02-27 | 2001-06-07 | Tanabe Seiyaku Co | Process for preparing optically active trans-3-substituted glycidic acid ester |
| US8025563B2 (en) | 2001-10-02 | 2011-09-27 | Universal Entertainment Corporation | Gaming machine |
| US7887410B2 (en) | 2001-10-02 | 2011-02-15 | Universal Entertainment Corporation | Gaming machine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1236467A (en) * | 1967-10-28 | 1971-06-23 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
| US3562257A (en) * | 1967-10-28 | 1971-02-09 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
| JPS5829779A (ja) * | 1981-08-17 | 1983-02-22 | Nippon Iyakuhin Kogyo Kk | Ｎ−アミノアルキル−１，５−ベンゾチアゼピン誘導体の製造法 |
| JPS5899471A (ja) * | 1981-12-07 | 1983-06-13 | Tanabe Seiyaku Co Ltd | ベンゾチアゼピン誘導体の新規製造法 |
| SE449611B (sv) * | 1982-07-09 | 1987-05-11 | Tanabe Seiyaku Co | Sett att framstella 1,5-bensotiazepinderivat |
| US4552695A (en) * | 1983-04-21 | 1985-11-12 | Shionogi & Co., Ltd. | Process for production of diltiazem hydrochloride |
| GB8316032D0 (en) * | 1983-06-11 | 1983-07-13 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
-
1984
- 1984-04-13 IL IL71538A patent/IL71538A/xx not_active IP Right Cessation
-
1985
- 1985-04-01 US US06/718,100 patent/US4566995A/en not_active Expired - Lifetime
- 1985-04-03 CA CA000478259A patent/CA1223585A/en not_active Expired
- 1985-04-05 AT AT85104182T patent/ATE65083T1/de not_active IP Right Cessation
- 1985-04-05 DE DE8585104182T patent/DE3583407D1/de not_active Expired - Fee Related
- 1985-04-05 EP EP85104182A patent/EP0158303B1/en not_active Expired - Lifetime
- 1985-04-12 ES ES542902A patent/ES542902A0/es active Granted
- 1985-04-12 JP JP60079156A patent/JPH06768B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3583407D1 (de) | 1991-08-14 |
| ATE65083T1 (de) | 1991-07-15 |
| ES8603704A1 (es) | 1986-01-01 |
| IL71538A (en) | 1987-07-31 |
| EP0158303B1 (en) | 1991-07-10 |
| CA1223585A (en) | 1987-06-30 |
| EP0158303A3 (en) | 1986-05-21 |
| IL71538A0 (en) | 1984-07-31 |
| JPS61118377A (ja) | 1986-06-05 |
| EP0158303A2 (en) | 1985-10-16 |
| JPH06768B2 (ja) | 1994-01-05 |
| US4566995A (en) | 1986-01-28 |
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