ES557776A0 - Un metodo para formar una tableta no comprimida que tiene una densidad menor que uno y capaz de flotar en el fluido gastrico "in vivo". - Google Patents
Un metodo para formar una tableta no comprimida que tiene una densidad menor que uno y capaz de flotar en el fluido gastrico "in vivo".Info
- Publication number
- ES557776A0 ES557776A0 ES557776A ES557776A ES557776A0 ES 557776 A0 ES557776 A0 ES 557776A0 ES 557776 A ES557776 A ES 557776A ES 557776 A ES557776 A ES 557776A ES 557776 A0 ES557776 A0 ES 557776A0
- Authority
- ES
- Spain
- Prior art keywords
- float
- vivo
- forming
- gastric fluid
- density less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 title 1
- 230000002496 gastric effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72283285A | 1985-04-12 | 1985-04-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES557776A0 true ES557776A0 (es) | 1988-07-16 |
| ES8802466A1 ES8802466A1 (es) | 1988-07-16 |
Family
ID=24903574
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES553900A Expired ES8800594A1 (es) | 1985-04-12 | 1986-04-11 | Un metodo para formar una tableta no comprimida que tiene una densidad menor que uno y capaz de flotar en jugo gastrico in vivo |
| ES557776A Expired ES8802466A1 (es) | 1985-04-12 | 1987-12-02 | Un metodo para formar una tableta no comprimida que tiene una densidad menor que uno y capaz de flotar en el fluido gastrico "in vivo". |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES553900A Expired ES8800594A1 (es) | 1985-04-12 | 1986-04-11 | Un metodo para formar una tableta no comprimida que tiene una densidad menor que uno y capaz de flotar en jugo gastrico in vivo |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4814179A (es) |
| JP (1) | JPS61246120A (es) |
| BE (1) | BE904899A (es) |
| DK (1) | DK162986A (es) |
| ES (2) | ES8800594A1 (es) |
| PL (1) | PL149493B1 (es) |
| SU (1) | SU1679965A3 (es) |
| YU (1) | YU58386A (es) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3803482A1 (de) * | 1988-02-05 | 1989-08-17 | Lohmann Therapie Syst Lts | Schwimmfaehiges orales therapeutisches system |
| US5158777A (en) * | 1990-02-16 | 1992-10-27 | E. R. Squibb & Sons, Inc. | Captopril formulation providing increased duration of activity |
| US5198229A (en) * | 1991-06-05 | 1993-03-30 | Alza Corporation | Self-retaining gastrointestinal delivery device |
| US5169638A (en) * | 1991-10-23 | 1992-12-08 | E. R. Squibb & Sons, Inc. | Buoyant controlled release powder formulation |
| IN186245B (es) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
| US6159491A (en) * | 1999-02-12 | 2000-12-12 | Biovector Technologies, Inc. | Prolonged release bioadhesive vaginal gel dosage form |
| DE10014588A1 (de) | 2000-03-27 | 2001-10-04 | Basf Ag | Wirkstoffhaltige Schwimmformen enthaltend Polyvinylacetat und Polyvinylpyrrolidon, deren Verwendung und Herstellung |
| US6955821B2 (en) * | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
| US7985420B2 (en) * | 2000-04-28 | 2011-07-26 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| US7838032B2 (en) * | 2000-04-28 | 2010-11-23 | Reckitt Benckiser Inc. | Sustained release of guaifenesin |
| US8012504B2 (en) * | 2000-04-28 | 2011-09-06 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| AU2008255254B2 (en) * | 2001-03-31 | 2010-12-09 | Jagotec Ag | A pharmaceutical tablet system that floats on gastric fluid for multipulse release of active substance and respective processes of producing same and a cup-shaped envelope of same |
| EP1245227A1 (en) * | 2001-03-31 | 2002-10-02 | Jagotec Ag | A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same |
| US20030138486A1 (en) * | 2001-10-29 | 2003-07-24 | King Pharmaceuticals Research | Methods and dosage forms for improving the bioavailability of therapeutic agents |
| CN1630513A (zh) * | 2002-02-04 | 2005-06-22 | 兰贝克赛实验室有限公司 | 流体动力平衡的以两相释放的口服药物输递系统 |
| BE1015608A6 (fr) * | 2003-07-15 | 2005-06-07 | Messadek Jallal | Traitement des arterites. |
| RU2216320C1 (ru) * | 2002-02-22 | 2003-11-20 | Мануйлов Борис Михайлович | Средство фарингал для профилактики и лечения инфекционно-воспалительных заболеваний ротоглотки |
| WO2003089506A1 (en) * | 2002-04-22 | 2003-10-30 | Purdue Research Foundation | Hydrogels having enhanced elasticity and mechanical strength properties |
| US20040109889A1 (en) * | 2002-12-04 | 2004-06-10 | Bunick Frank J. | Surface treatment composition for soft substrates |
| NZ523946A (en) * | 2003-01-31 | 2004-06-25 | Carl Ernest Alexander | Portable hygiene compositions comprising a semi-solid gel and active ingredients in bead form for use in personal oral, dental or skin care |
| ES2278314T3 (es) * | 2003-04-17 | 2007-08-01 | Jallal Messadek | Formulaciones orales para la liberacion controlada de la betaina. |
| US20060128657A1 (en) * | 2003-08-04 | 2006-06-15 | Jallal Messadek | Selected betaines and their uses |
| BE1016128A6 (fr) * | 2004-07-22 | 2006-03-07 | Messadek Jallal | Combinaisons therapeutiques |
| WO2006050581A2 (en) * | 2004-11-10 | 2006-05-18 | Jallal Messadek | Betaine as agent against arthropod - or mosquito -borne diseases |
| WO2006086856A1 (en) | 2005-02-15 | 2006-08-24 | Messadek, Jallal | Combination therapeutic compositions and method of use |
| ATE540690T1 (de) * | 2005-04-27 | 2012-01-15 | Jallal Messadek | Insulinkombinationen |
| US20070178155A1 (en) * | 2006-01-31 | 2007-08-02 | Jiang David Yihai | Preparation for gastric buoyant sustained drug release dosage form |
| AT505225A1 (de) | 2007-04-26 | 2008-11-15 | Sanochemia Pharmazeutika Ag | 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen |
| WO2009065193A1 (en) * | 2007-11-21 | 2009-05-28 | Jallal Messadek | Treatment of aspirin resistance with betaine and/or betaine enriched molasses |
| EP2133071A1 (en) | 2008-06-09 | 2009-12-16 | Université de la Méditerranée | Process for making gastroretentive dosage forms |
| US20100249423A1 (en) * | 2009-03-09 | 2010-09-30 | Sanochemia Pharmazeutika Ag | Tolperisone controlled release tablet |
| EP2444064A1 (en) | 2010-10-22 | 2012-04-25 | Meliatys | Process for making multiparticulate gastroretentive dosage forms |
| EP2827839B1 (en) | 2012-03-20 | 2019-02-27 | Particle Dynamics International, LLC | Gelling agent-based dosage form |
| ES2536836T3 (es) | 2012-10-12 | 2015-05-29 | Omya International Ag | Formulación de medicamento gastrorretentivo y sistemas de liberación y su método de preparación usando carbonato de calcio transformado en funcional |
| PL235144B1 (pl) | 2014-06-03 | 2020-06-01 | Univ Medyczny Im Piastow Slaskich We Wroclawiu | Sposób wytwarzania tabletki flotacyjnej o przedłużonym oddziaływaniu substancji leczniczych z błoną śluzową żołądka oraz kompozycja farmaceutyczna |
| GB201506755D0 (en) | 2015-04-21 | 2015-06-03 | Reckitt Benckiser Llc | Novel pharmaceutical formulation |
| EP3034070A1 (en) | 2014-12-18 | 2016-06-22 | Omya International AG | Method for the production of a pharmaceutical delivery system |
| EP3069713A1 (en) | 2015-03-20 | 2016-09-21 | Omya International AG | Dispersible dosage form |
| US11278506B2 (en) | 2015-10-09 | 2022-03-22 | Rb Health (Us) Llc | Pharmaceutical formulation |
| EP3269361A1 (en) | 2016-07-14 | 2018-01-17 | Omya International AG | Dosage form |
| US11389398B2 (en) | 2019-05-14 | 2022-07-19 | Clexio Biosciences Ltd. | Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease |
| WO2022195476A1 (en) | 2021-03-15 | 2022-09-22 | Clexio Biosciences Ltd. | Gastroretentive devices for assessment of intragastric conditions |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3323922A (en) * | 1965-08-09 | 1967-06-06 | Pillsbury Co | Protective coatings |
| US3483002A (en) * | 1966-11-15 | 1969-12-09 | Kohnstamm & Co Inc H | Gelatinous coloring composition and process |
| US4126672A (en) * | 1976-02-04 | 1978-11-21 | Hoffmann-La Roche Inc. | Sustained release pharmaceutical capsules |
| US4140755A (en) * | 1976-02-13 | 1979-02-20 | Hoffmann-La Roche Inc. | Sustained release tablet formulations |
| US4167558A (en) * | 1976-02-13 | 1979-09-11 | Hoffmann-La Roche Inc. | Novel sustained release tablet formulations |
| US4089981A (en) * | 1976-06-04 | 1978-05-16 | Maxfibe Foods, Inc. | Fibrous simulated food product with gel structure |
| US4434153A (en) * | 1982-03-22 | 1984-02-28 | Alza Corporation | Drug delivery system comprising a reservoir containing a plurality of tiny pills |
| US4451260A (en) * | 1982-03-26 | 1984-05-29 | Minnesota Mining And Manufacturing Company | Sustained release oral medicinal delivery device |
| FR2537844B1 (fr) * | 1982-12-17 | 1985-08-23 | Roquette Freres | Pastilles du type lozenge a base de sorbitol ou de fructose cristallise et leur procede de fabrication |
| JPS6124516A (ja) * | 1984-07-12 | 1986-02-03 | Fujisawa Pharmaceut Co Ltd | 持続性錠剤 |
| JPS6143108A (ja) * | 1984-08-03 | 1986-03-01 | Nippon Shinyaku Co Ltd | 医薬品製剤及びその製造法 |
| GB8507779D0 (en) * | 1985-03-26 | 1985-05-01 | Fujisawa Pharmaceutical Co | Drug carrier |
-
1986
- 1986-04-10 DK DK162986A patent/DK162986A/da not_active IP Right Cessation
- 1986-04-10 PL PL1986258891A patent/PL149493B1/pl unknown
- 1986-04-11 JP JP61084015A patent/JPS61246120A/ja active Pending
- 1986-04-11 SU SU864027295A patent/SU1679965A3/ru active
- 1986-04-11 ES ES553900A patent/ES8800594A1/es not_active Expired
- 1986-04-11 YU YU00583/86A patent/YU58386A/xx unknown
- 1986-06-10 BE BE0/216765A patent/BE904899A/fr not_active IP Right Cessation
-
1987
- 1987-03-17 US US07/026,640 patent/US4814179A/en not_active Expired - Fee Related
- 1987-12-02 ES ES557776A patent/ES8802466A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK162986D0 (da) | 1986-04-10 |
| SU1679965A3 (ru) | 1991-09-23 |
| ES553900A0 (es) | 1987-11-01 |
| BE904899A (fr) | 1986-10-01 |
| DK162986A (da) | 1986-10-13 |
| ES8802466A1 (es) | 1988-07-16 |
| YU58386A (en) | 1987-10-31 |
| ES8800594A1 (es) | 1987-11-01 |
| JPS61246120A (ja) | 1986-11-01 |
| PL149493B1 (en) | 1990-02-28 |
| US4814179A (en) | 1989-03-21 |
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