ES8308571A1 - Procedimiento para preparar complejos de inclusion de esteroides pobremente solubles en agua con -ciclodextrina. - Google Patents

Procedimiento para preparar complejos de inclusion de esteroides pobremente solubles en agua con -ciclodextrina.

Info

Publication number
ES8308571A1
ES8308571A1 ES516840A ES516840A ES8308571A1 ES 8308571 A1 ES8308571 A1 ES 8308571A1 ES 516840 A ES516840 A ES 516840A ES 516840 A ES516840 A ES 516840A ES 8308571 A1 ES8308571 A1 ES 8308571A1
Authority
ES
Spain
Prior art keywords
cyclodextrin
water
procedure
reichstein
poorly soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516840A
Other languages
English (en)
Spanish (es)
Other versions
ES516840A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES516840A0 publication Critical patent/ES516840A0/es
Publication of ES8308571A1 publication Critical patent/ES8308571A1/es
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES516840A 1981-10-27 1982-10-26 Procedimiento para preparar complejos de inclusion de esteroides pobremente solubles en agua con -ciclodextrina. Expired ES8308571A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU813147A HU190356B (en) 1981-10-27 1981-10-27 Process for preparing steroid-gamma-cyclodextrin inclusion complexes with high water-solubility

Publications (2)

Publication Number Publication Date
ES516840A0 ES516840A0 (es) 1983-09-16
ES8308571A1 true ES8308571A1 (es) 1983-09-16

Family

ID=10962794

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516840A Expired ES8308571A1 (es) 1981-10-27 1982-10-26 Procedimiento para preparar complejos de inclusion de esteroides pobremente solubles en agua con -ciclodextrina.

Country Status (12)

Country Link
JP (1) JPS5883699A (fr)
BE (1) BE894825A (fr)
DD (1) DD208549A5 (fr)
DE (1) DE3238800A1 (fr)
DK (1) DK474782A (fr)
ES (1) ES8308571A1 (fr)
FR (1) FR2515187A1 (fr)
GB (1) GB2109381A (fr)
HU (1) HU190356B (fr)
IT (1) IT1191049B (fr)
NL (1) NL8204122A (fr)
SE (1) SE8206055L (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196230B (en) * 1983-12-29 1988-10-28 Chinoin Gyogyszer Es Vegyeszet Process for producing water-soluble forms of polyene antibiotics and pharmaceutics comprising such active ingredient and plant protective with antifungal effect
GB2162529B (en) * 1984-06-08 1988-03-02 Nitrokemia Ipartelepek B-cyclodextrin complex of benzene sulphonyl urea derivatives
US5223295A (en) * 1988-01-22 1993-06-29 Asterol International Process for the elimination of steroid compounds contained in substance of biological origin
EP0381747A4 (en) * 1988-08-15 1991-09-11 American Maize-Products Company Water soluble branched beta cyclodextrin steroid complex
US5229370A (en) * 1988-08-15 1993-07-20 Ammeraal Robert N Water soluble branched beta cyclodextrin steroid complex
EP0540751A4 (en) * 1991-05-20 1994-10-26 Eisai Co Ltd Steroid compound combined with polysaccharide
US20040152664A1 (en) * 1998-09-02 2004-08-05 Allergan, Inc. Prednisolone compositions
AU2002220654A1 (en) * 2000-11-02 2002-05-15 Akzo Nobel N.V. Use of cortisol-sequestering agents for the treatment of hypercortisolaemia related disorders
EP1216713A1 (fr) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Compositions de complexes de estrogen-cyclodextrine
JP5350572B2 (ja) * 2000-12-20 2013-11-27 バイエル ファーマ アクチエンゲゼルシャフト シクロデキストリン−ドロスピレノン封入複合体
EP1216712A1 (fr) 2000-12-20 2002-06-26 Schering Aktiengesellschaft Complexes d'inclusion de drospirenone et de cyclodextrines
US20070020298A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US12370352B2 (en) 2007-06-28 2025-07-29 Cydex Pharmaceuticals, Inc. Nasal and ophthalmic delivery of aqueous corticosteroid solutions
US20150031532A1 (en) * 2012-03-13 2015-01-29 Amphidex A/S Production Of Stabilized Channel Type Cyclodextrin Crystals
WO2025068481A1 (fr) * 2023-09-29 2025-04-03 Institut National de la Santé et de la Recherche Médicale Formulations de gouttes oculaires de spironolactone

Also Published As

Publication number Publication date
JPS5883699A (ja) 1983-05-19
NL8204122A (nl) 1983-05-16
BE894825A (fr) 1983-02-14
SE8206055L (sv) 1983-04-28
HU190356B (en) 1986-08-28
ES516840A0 (es) 1983-09-16
DK474782A (da) 1983-04-28
IT8223942A1 (it) 1984-04-26
IT8223942A0 (it) 1982-10-26
DD208549A5 (de) 1984-04-04
DE3238800A1 (de) 1983-05-05
FR2515187A1 (fr) 1983-04-29
IT1191049B (it) 1988-02-24
SE8206055D0 (sv) 1982-10-25
GB2109381A (en) 1983-06-02

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