JPS5883699A - γ−サイクロデキストリンとステロイドとの包摂複合体、及びその製造方法、並びに該包摂複合体を含有する医薬 - Google Patents
γ−サイクロデキストリンとステロイドとの包摂複合体、及びその製造方法、並びに該包摂複合体を含有する医薬Info
- Publication number
- JPS5883699A JPS5883699A JP57187658A JP18765882A JPS5883699A JP S5883699 A JPS5883699 A JP S5883699A JP 57187658 A JP57187658 A JP 57187658A JP 18765882 A JP18765882 A JP 18765882A JP S5883699 A JPS5883699 A JP S5883699A
- Authority
- JP
- Japan
- Prior art keywords
- cyclodextrin
- steroid
- complex
- water
- spironolactone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nanotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU813147A HU190356B (en) | 1981-10-27 | 1981-10-27 | Process for preparing steroid-gamma-cyclodextrin inclusion complexes with high water-solubility |
| HU3147/81 | 1981-10-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5883699A true JPS5883699A (ja) | 1983-05-19 |
Family
ID=10962794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57187658A Pending JPS5883699A (ja) | 1981-10-27 | 1982-10-27 | γ−サイクロデキストリンとステロイドとの包摂複合体、及びその製造方法、並びに該包摂複合体を含有する医薬 |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS5883699A (fr) |
| BE (1) | BE894825A (fr) |
| DD (1) | DD208549A5 (fr) |
| DE (1) | DE3238800A1 (fr) |
| DK (1) | DK474782A (fr) |
| ES (1) | ES516840A0 (fr) |
| FR (1) | FR2515187A1 (fr) |
| GB (1) | GB2109381A (fr) |
| HU (1) | HU190356B (fr) |
| IT (1) | IT1191049B (fr) |
| NL (1) | NL8204122A (fr) |
| SE (1) | SE8206055L (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992020699A1 (fr) * | 1991-05-20 | 1992-11-26 | Eisai Co., Ltd. | Compose steroide combine avec du polysaccharide |
| JP2004520306A (ja) * | 2000-12-20 | 2004-07-08 | シエーリング アクチエンゲゼルシャフト | シクロデキストリン−ドロスピレノン封入複合体 |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU196230B (en) * | 1983-12-29 | 1988-10-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing water-soluble forms of polyene antibiotics and pharmaceutics comprising such active ingredient and plant protective with antifungal effect |
| GB2162529B (en) * | 1984-06-08 | 1988-03-02 | Nitrokemia Ipartelepek | B-cyclodextrin complex of benzene sulphonyl urea derivatives |
| US5223295A (en) * | 1988-01-22 | 1993-06-29 | Asterol International | Process for the elimination of steroid compounds contained in substance of biological origin |
| EP0381747A4 (en) * | 1988-08-15 | 1991-09-11 | American Maize-Products Company | Water soluble branched beta cyclodextrin steroid complex |
| US5229370A (en) * | 1988-08-15 | 1993-07-20 | Ammeraal Robert N | Water soluble branched beta cyclodextrin steroid complex |
| US20040152664A1 (en) * | 1998-09-02 | 2004-08-05 | Allergan, Inc. | Prednisolone compositions |
| US20040048830A1 (en) * | 2000-11-02 | 2004-03-11 | Mingqiang Zhang | Use of cortisol-sequestering agents for the treatment of hypercortisolaemia related disorders |
| EP1216712A1 (fr) * | 2000-12-20 | 2002-06-26 | Schering Aktiengesellschaft | Complexes d'inclusion de drospirenone et de cyclodextrines |
| EP1216713A1 (fr) | 2000-12-20 | 2002-06-26 | Schering Aktiengesellschaft | Compositions de complexes de estrogen-cyclodextrine |
| US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
| US20070020298A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid |
| US12370352B2 (en) | 2007-06-28 | 2025-07-29 | Cydex Pharmaceuticals, Inc. | Nasal and ophthalmic delivery of aqueous corticosteroid solutions |
| WO2013135248A2 (fr) * | 2012-03-13 | 2013-09-19 | Amphidex A/S | Production de cristaux de cyclodextrine de type canal |
| WO2025068481A1 (fr) * | 2023-09-29 | 2025-04-03 | Institut National de la Santé et de la Recherche Médicale | Formulations de gouttes oculaires de spironolactone |
-
1981
- 1981-10-27 HU HU813147A patent/HU190356B/hu not_active IP Right Cessation
-
1982
- 1982-10-20 DE DE19823238800 patent/DE3238800A1/de not_active Withdrawn
- 1982-10-25 SE SE8206055A patent/SE8206055L/xx not_active Application Discontinuation
- 1982-10-26 DD DD82244272A patent/DD208549A5/de unknown
- 1982-10-26 GB GB08230513A patent/GB2109381A/en not_active Withdrawn
- 1982-10-26 DK DK474782A patent/DK474782A/da not_active Application Discontinuation
- 1982-10-26 ES ES516840A patent/ES516840A0/es active Granted
- 1982-10-26 FR FR8217943A patent/FR2515187A1/fr not_active Withdrawn
- 1982-10-26 NL NL8204122A patent/NL8204122A/nl not_active Application Discontinuation
- 1982-10-26 IT IT23942/82A patent/IT1191049B/it active
- 1982-10-27 BE BE0/209341A patent/BE894825A/fr not_active IP Right Cessation
- 1982-10-27 JP JP57187658A patent/JPS5883699A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992020699A1 (fr) * | 1991-05-20 | 1992-11-26 | Eisai Co., Ltd. | Compose steroide combine avec du polysaccharide |
| JP2004520306A (ja) * | 2000-12-20 | 2004-07-08 | シエーリング アクチエンゲゼルシャフト | シクロデキストリン−ドロスピレノン封入複合体 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES8308571A1 (es) | 1983-09-16 |
| SE8206055L (sv) | 1983-04-28 |
| HU190356B (en) | 1986-08-28 |
| IT8223942A1 (it) | 1984-04-26 |
| FR2515187A1 (fr) | 1983-04-29 |
| IT1191049B (it) | 1988-02-24 |
| SE8206055D0 (sv) | 1982-10-25 |
| ES516840A0 (es) | 1983-09-16 |
| BE894825A (fr) | 1983-02-14 |
| NL8204122A (nl) | 1983-05-16 |
| DK474782A (da) | 1983-04-28 |
| DD208549A5 (de) | 1984-04-04 |
| GB2109381A (en) | 1983-06-02 |
| IT8223942A0 (it) | 1982-10-26 |
| DE3238800A1 (de) | 1983-05-05 |
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