FI58067C - Kosmetiska preparat foer utvaertes bruk - Google Patents

Kosmetiska preparat foer utvaertes bruk Download PDF

Info

Publication number: FI58067C
Authority: FI; Finland
Prior art keywords: estradiol; weight; caffeine; ingredients; alcohol
Prior art date: 1973-10-06

Application number

FI2909/74A

Other languages

English (en)

Finnish (fi)

Other versions

FI58067B (fi

FI290974A7 (it

Inventor

Hans Schaefer

Guenter Stuettgen

Original Assignee

Hahn Carl Dr Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-06

Filing date

1974-10-04

Publication date

1980-12-10

1974-10-04 Application filed by Hahn Carl Dr Gmbh filed Critical Hahn Carl Dr Gmbh

1975-04-07 Publication of FI290974A7 publication Critical patent/FI290974A7/fi

1980-08-29 Application granted granted Critical

1980-08-29 Publication of FI58067B publication Critical patent/FI58067B/fi

1980-12-10 Publication of FI58067C publication Critical patent/FI58067C/fi

Links

239000002537 cosmetic Substances 0.000 title claims description 6
238000002360 preparation method Methods 0.000 title description 20
RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims description 45
229920000669 heparin Polymers 0.000 claims description 14
229960002897 heparin Drugs 0.000 claims description 14
-1 alkali metal cation Chemical class 0.000 claims description 11
150000001875 compounds Chemical class 0.000 claims description 11
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 7
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 7
239000004480 active ingredient Substances 0.000 claims description 5
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 5
229920001499 Heparinoid Polymers 0.000 claims description 3
239000002554 heparinoid Substances 0.000 claims description 3
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 2
229910052783 alkali metal Inorganic materials 0.000 claims description 2
125000004432 carbon atom Chemical group C* 0.000 claims description 2
125000005313 fatty acid group Chemical group 0.000 claims description 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
125000001424 substituent group Chemical group 0.000 claims description 2
239000000203 mixture Substances 0.000 description 23
LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 21
229960001948 caffeine Drugs 0.000 description 21
VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 21
239000004615 ingredient Substances 0.000 description 19
229960005309 estradiol Drugs 0.000 description 18
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 18
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 17
VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 15
239000003755 preservative agent Substances 0.000 description 15
230000002335 preservative effect Effects 0.000 description 14
235000019441 ethanol Nutrition 0.000 description 13
201000004384 Alopecia Diseases 0.000 description 9
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 9
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 8
239000012153 distilled water Substances 0.000 description 8
239000000499 gel Substances 0.000 description 8
230000003676 hair loss Effects 0.000 description 8
OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical class CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 8
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 7
235000014113 dietary fatty acids Nutrition 0.000 description 7
239000000839 emulsion Substances 0.000 description 7
238000002474 experimental method Methods 0.000 description 7
229930195729 fatty acid Natural products 0.000 description 7
239000000194 fatty acid Substances 0.000 description 7
239000000787 lecithin Substances 0.000 description 7
229940067606 lecithin Drugs 0.000 description 7
235000010445 lecithin Nutrition 0.000 description 7
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
230000000694 effects Effects 0.000 description 6
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 6
LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 description 5
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Natural products OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 5
229930182833 estradiol Natural products 0.000 description 5
229920005862 polyol Polymers 0.000 description 5
210000004761 scalp Anatomy 0.000 description 5
159000000000 sodium salts Chemical class 0.000 description 5
VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 4
LVDKZNITIUWNER-UHFFFAOYSA-N Bronopol Chemical compound OCC(Br)(CO)[N+]([O-])=O LVDKZNITIUWNER-UHFFFAOYSA-N 0.000 description 4
230000001548 androgenic effect Effects 0.000 description 4
239000003963 antioxidant agent Substances 0.000 description 4
230000003078 antioxidant effect Effects 0.000 description 4
239000006071 cream Substances 0.000 description 4
SASYSVUEVMOWPL-NXVVXOECSA-N decyl oleate Chemical compound CCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC SASYSVUEVMOWPL-NXVVXOECSA-N 0.000 description 4
208000024963 hair loss Diseases 0.000 description 4
GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 4
IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 4
239000012071 phase Substances 0.000 description 4
229960001295 tocopherol Drugs 0.000 description 4
239000011732 tocopherol Substances 0.000 description 4
LDSYPJSYQOUQMN-WAJSLEGFSA-N (8R,9S,13S,14S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol sulfuric acid Chemical compound OS(O)(=O)=O.OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)O)[C@@H]4[C@@H]3CCC2=C1 LDSYPJSYQOUQMN-WAJSLEGFSA-N 0.000 description 3
208000002874 Acne Vulgaris Diseases 0.000 description 3
206010000496 acne Diseases 0.000 description 3
235000012000 cholesterol Nutrition 0.000 description 3
150000002148 esters Chemical class 0.000 description 3
239000000262 estrogen Substances 0.000 description 3
229940011871 estrogen Drugs 0.000 description 3
210000004209 hair Anatomy 0.000 description 3
XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 3
239000002304 perfume Substances 0.000 description 3
230000009467 reduction Effects 0.000 description 3
238000003756 stirring Methods 0.000 description 3
LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 description 2
235000021314 Palmitic acid Nutrition 0.000 description 2
235000019483 Peanut oil Nutrition 0.000 description 2
235000021355 Stearic acid Nutrition 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
239000002253 acid Substances 0.000 description 2
230000003698 anagen phase Effects 0.000 description 2
229960003168 bronopol Drugs 0.000 description 2
239000007765 cera alba Substances 0.000 description 2
238000009472 formulation Methods 0.000 description 2
YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 2
SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 2
210000003128 head Anatomy 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
239000000312 peanut oil Substances 0.000 description 2
239000003531 protein hydrolysate Substances 0.000 description 2
229920006395 saturated elastomer Polymers 0.000 description 2
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 2
YAPQBXQYLJRXSA-UHFFFAOYSA-N theobromine Chemical compound CN1C(=O)NC(=O)C2=C1N=CN2C YAPQBXQYLJRXSA-UHFFFAOYSA-N 0.000 description 2
ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 description 2
229940075420 xanthine Drugs 0.000 description 2
CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
240000009226 Corylus americana Species 0.000 description 1
235000001543 Corylus americana Nutrition 0.000 description 1
235000007466 Corylus avellana Nutrition 0.000 description 1
LVGKNOAMLMIIKO-UHFFFAOYSA-N Elaidinsaeure-aethylester Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC LVGKNOAMLMIIKO-UHFFFAOYSA-N 0.000 description 1
JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
208000019255 Menstrual disease Diseases 0.000 description 1
208000019695 Migraine disease Diseases 0.000 description 1
206010067572 Oestrogenic effect Diseases 0.000 description 1
239000004264 Petrolatum Substances 0.000 description 1
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
229920002125 Sokalan® Polymers 0.000 description 1
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
VQHQLBARMFAKSV-AANPDWTMSA-N [(8r,9s,13s,14s,17s)-3-acetyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] acetate Chemical compound C1CC2=CC(OC(C)=O)=CC=C2[C@@H]2[C@@H]1[C@@H]1CC[C@H](OC(=O)C)[C@@]1(C)CC2 VQHQLBARMFAKSV-AANPDWTMSA-N 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
239000013543 active substance Substances 0.000 description 1
230000002730 additional effect Effects 0.000 description 1
230000001476 alcoholic effect Effects 0.000 description 1
125000005907 alkyl ester group Chemical group 0.000 description 1
231100000360 alopecia Toxicity 0.000 description 1
239000008346 aqueous phase Substances 0.000 description 1
235000013871 bee wax Nutrition 0.000 description 1
239000012166 beeswax Substances 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
210000000481 breast Anatomy 0.000 description 1
239000000872 buffer Substances 0.000 description 1
230000003139 buffering effect Effects 0.000 description 1
239000003086 colorant Substances 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
239000003246 corticosteroid Substances 0.000 description 1
GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
239000002274 desiccant Substances 0.000 description 1
150000001993 dienes Chemical class 0.000 description 1
239000003085 diluting agent Substances 0.000 description 1
BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
229910000397 disodium phosphate Inorganic materials 0.000 description 1
235000019800 disodium phosphate Nutrition 0.000 description 1
230000001076 estrogenic effect Effects 0.000 description 1
238000007046 ethoxylation reaction Methods 0.000 description 1
LVGKNOAMLMIIKO-QXMHVHEDSA-N ethyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC LVGKNOAMLMIIKO-QXMHVHEDSA-N 0.000 description 1
150000004665 fatty acids Chemical class 0.000 description 1
210000001061 forehead Anatomy 0.000 description 1
201000000079 gynecomastia Diseases 0.000 description 1
230000003779 hair growth Effects 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
229940001447 lactate Drugs 0.000 description 1
239000004310 lactic acid Substances 0.000 description 1
235000014655 lactic acid Nutrition 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
206010027599 migraine Diseases 0.000 description 1
229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
235000019796 monopotassium phosphate Nutrition 0.000 description 1
WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 description 1
150000007523 nucleic acids Chemical class 0.000 description 1
102000039446 nucleic acids Human genes 0.000 description 1
108020004707 nucleic acids Proteins 0.000 description 1
OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
239000003921 oil Substances 0.000 description 1
230000035515 penetration Effects 0.000 description 1
WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
229940066842 petrolatum Drugs 0.000 description 1
235000019271 petrolatum Nutrition 0.000 description 1
239000008363 phosphate buffer Substances 0.000 description 1
239000004584 polyacrylic acid Substances 0.000 description 1
150000003077 polyols Chemical class 0.000 description 1
229910052573 porcelain Inorganic materials 0.000 description 1
GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
LWIHDJKSTIGBAC-UHFFFAOYSA-K potassium phosphate Substances [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 1
230000002265 prevention Effects 0.000 description 1
150000003212 purines Chemical class 0.000 description 1
150000003230 pyrimidines Chemical class 0.000 description 1
239000011734 sodium Substances 0.000 description 1
239000001540 sodium lactate Substances 0.000 description 1
229940005581 sodium lactate Drugs 0.000 description 1
235000011088 sodium lactate Nutrition 0.000 description 1
239000001488 sodium phosphate Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
239000008117 stearic acid Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
229910021653 sulphate ion Inorganic materials 0.000 description 1
230000002195 synergetic effect Effects 0.000 description 1
229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 description 1
230000003797 telogen phase Effects 0.000 description 1
229960004559 theobromine Drugs 0.000 description 1
229960000278 theophylline Drugs 0.000 description 1
235000010384 tocopherol Nutrition 0.000 description 1
229930003799 tocopherol Natural products 0.000 description 1
210000000689 upper leg Anatomy 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
239000007762 w/o emulsion Substances 0.000 description 1
GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Birds (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)

FI2909/74A 1973-10-06 1974-10-04 Kosmetiska preparat foer utvaertes bruk FI58067C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2350315		1973-10-06
DE2350315A DE2350315C2 (de)	1973-10-06	1973-10-06	Pharmazeutische und kosmetische Präparate zur äußerlichen Anwendung

Publications (3)

Publication Number	Publication Date
FI290974A7 FI290974A7 (it)	1975-04-07
FI58067B FI58067B (fi)	1980-08-29
FI58067C true FI58067C (fi)	1980-12-10

Family

ID=5894742

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI2909/74A FI58067C (fi)	1973-10-06	1974-10-04	Kosmetiska preparat foer utvaertes bruk

Country Status (18)

Country	Link
US (1)	US4390532A (it)
JP (1)	JPS5064442A (it)
AR (2)	AR216737A1 (it)
AT (1)	AT350730B (it)
BE (1)	BE820347A (it)
CA (1)	CA1032080A (it)
CH (1)	CH614119A5 (it)
DE (1)	DE2350315C2 (it)
DK (1)	DK138725C (it)
FI (1)	FI58067C (it)
FR (1)	FR2246272B1 (it)
GB (1)	GB1456590A (it)
IE (1)	IE39936B1 (it)
IT (1)	IT1045535B (it)
LU (1)	LU70997A1 (it)
NL (1)	NL7413085A (it)
NO (1)	NO141144C (it)
SE (1)	SE405937B (it)

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JPS5925311A (ja) *	1982-07-29	1984-02-09	Shiseido Co Ltd	化粧料
CH655656B (it) *	1982-10-07	1986-05-15
US4720489A (en) *	1984-10-15	1988-01-19	Douglas Shander	Hair growth modification with ornithine decarboxylase inhibitors
DE3608852A1 (de) *	1986-03-17	1987-09-24	Henkel Kgaa	Sebosuppressive zubereitungen
IT1203331B (it) *	1987-02-06	1989-02-15	Tonfer Inc	Composizione per il trattamento e la stimolazione della crescita dei capelli
FR2643909B1 (fr) *	1989-03-03	1993-01-22	Bioetica Sa	Composition de base pour la preparation d'une composition cosmetique formant composition capillaire et composition cosmetique formant composition capillaire ainsi preparee, contenant de l'heparine ou de l'heparane sulfate
DK191889D0 (da) *	1989-04-20	1989-04-20	Bukh Meditec	Kosmetisk middel
FR2676649B1 (fr) *	1991-05-22	1994-02-25	Lvmh Recherche	Composition cosmetique ou pharmaceutique, notamment dermatologique, destinee a favoriser la pigmentation de la peau ou des cheveux, contenant un extrait de cyperus et son procede de fabrication.
US5407944A (en) *	1993-02-19	1995-04-18	Goldman; Boris E.	Compositions and methods for promoting hair growth
JPH0826961A (ja) *	1994-07-12	1996-01-30	Kao Corp	皮膚外用剤組成物
AU740783B2 (en) *	1996-09-18	2001-11-15	Applied Genetics Incorporated Dermatics	Pharmaceutical compositions and methods
US6623724B2 (en)	1996-09-18	2003-09-23	Applied Genetics Incorporated Dermatics	Dermatological compositions and methods
US6436946B1 (en) *	1997-05-02	2002-08-20	Morris A. Mann	Xanthine-containing compositions for oral administration and uses related thereto
AU754680B2 (en) *	1997-08-21	2002-11-21	Johnson & Johnson Consumer Companies, Inc.	Use of 17-alpha-estradiol for the treatment of aged or sundamaged skin and/or skin atrophy
US6488940B2 (en) *	1997-08-21	2002-12-03	Johnson & Johnson Consumer Companies, Inc.	Use of 17-α-estradiol for the treatment of aged or sundamaged skin and/or skin atrophy
US20020052390A1 (en) *	1997-10-22	2002-05-02	Jens Ponikau	Methods and materials for treating and preventing inflammation of mucosal tissue
JP2003527310A (ja) *	1999-04-16	2003-09-16	イエナフアルムゲーエムベーハーウントツェーオー．カーゲー	エストロゲンを局部的に皮内投与するための医薬品組成物または化粧品組成物
US20070225379A1 (en) *	2001-08-03	2007-09-27	Carrara Dario Norberto R	Transdermal delivery of systemically active central nervous system drugs
WO2005039531A1 (en) *	2003-10-10	2005-05-06	Antares Pharma Ipl Ag	Transdermal pharmaceutical formulation for minimizing skin residues
US7198801B2 (en) *	2000-08-03	2007-04-03	Antares Pharma Ipl Ag	Formulations for transdermal or transmucosal application
WO2002011768A1 (en)	2000-08-03	2002-02-14	Antares Pharma Ipl Ag	Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels
US8980290B2 (en)	2000-08-03	2015-03-17	Antares Pharma Ipl Ag	Transdermal compositions for anticholinergic agents
US20040198706A1 (en) *	2003-03-11	2004-10-07	Carrara Dario Norberto R.	Methods and formulations for transdermal or transmucosal application of active agents
US20040175347A1 (en) *	2003-03-04	2004-09-09	The Procter & Gamble Company	Regulation of mammalian keratinous tissue using hexamidine compositions
US7407623B2 (en) *	2003-12-09	2008-08-05	Ge Betz, Inc.	Steam condensate corrosion inhibitor compositions and methods
US7425340B2 (en) *	2004-05-07	2008-09-16	Antares Pharma Ipl Ag	Permeation enhancing compositions for anticholinergic agents
US20050276765A1 (en) *	2004-06-10	2005-12-15	Paul Nghiem	Preventing skin damage
WO2006125642A1 (en)	2005-05-27	2006-11-30	Antares Pharma Ipl Ag	Methods and apparatus for transdermal or transmucosal application of testosterone
NZ571460A (en)	2006-04-21	2010-10-29	Antares Pharma Ipl Ag	Methods of treating hot flashes with formulations for transdermal or transmucosal application
WO2008067991A2 (en) *	2006-12-08	2008-06-12	Antares Pharma Ipl Ag	Skin-friendly drug complexes for transdermal administration

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DE1765165B2 (de) *	1968-04-11	1976-08-05	Langen & Co, 4000 Düsseldorf	Druckschalter fuer hydraulische speicherkreislaeufe
GB1337198A (en) *	1971-04-21	1973-11-14	Rech Et Dapplications Scient S	Oestratriene diethers
US3826834A (en) *	1971-05-19	1974-07-30	A Reiches	Use of vitamin b6 for enlarging subnormal hair bulbs and enhancing hair growth therefrom

1973
- 1973-10-06 DE DE2350315A patent/DE2350315C2/de not_active Expired
1974
- 1974-09-17 NO NO743342A patent/NO141144C/no unknown
- 1974-09-24 FR FR7432153A patent/FR2246272B1/fr not_active Expired
- 1974-09-25 LU LU70997A patent/LU70997A1/xx unknown
- 1974-09-25 BE BE148901A patent/BE820347A/xx not_active IP Right Cessation
- 1974-09-27 CA CA210,272A patent/CA1032080A/en not_active Expired
- 1974-10-01 AT AT788374A patent/AT350730B/de not_active IP Right Cessation
- 1974-10-03 DK DK521574A patent/DK138725C/da not_active IP Right Cessation
- 1974-10-03 NL NL7413085A patent/NL7413085A/xx not_active Application Discontinuation
- 1974-10-04 SE SE7412528A patent/SE405937B/xx unknown
- 1974-10-04 IE IE2062/74A patent/IE39936B1/xx unknown
- 1974-10-04 AR AR255929A patent/AR216737A1/es active
- 1974-10-04 CH CH1338574A patent/CH614119A5/xx not_active IP Right Cessation
- 1974-10-04 GB GB4322074A patent/GB1456590A/en not_active Expired
- 1974-10-04 FI FI2909/74A patent/FI58067C/fi active
- 1974-10-04 IT IT53370/74A patent/IT1045535B/it active
- 1974-10-07 JP JP49114809A patent/JPS5064442A/ja active Pending
1975
- 1975-04-12 AR AR262849A patent/AR220095A1/es active
1978
- 1978-03-08 US US05/884,452 patent/US4390532A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NL7413085A (nl)	1975-04-08
ATA788374A (de)	1978-11-15
SE405937B (sv)	1979-01-15
CH614119A5 (it)	1979-11-15
DK138725C (da)	1979-04-02
NO141144B (no)	1979-10-15
CA1032080A (en)	1978-05-30
NO141144C (no)	1980-01-23
DE2350315C2 (de)	1984-01-12
AT350730B (de)	1979-06-11
DK138725B (da)	1978-10-23
IE39936B1 (en)	1979-01-31
LU70997A1 (it)	1975-03-06
AR220095A1 (es)	1980-10-15
FR2246272B1 (it)	1977-07-01
DE2350315A1 (de)	1975-04-17
BE820347A (fr)	1975-03-25
AU7353674A (en)	1976-03-25
US4390532A (en)	1983-06-28
FR2246272A1 (it)	1975-05-02
FI58067B (fi)	1980-08-29
IE39936L (en)	1975-04-06
SE7412528L (it)	1975-04-07
DK521574A (it)	1975-06-09
NO743342L (it)	1975-05-05
AR216737A1 (es)	1980-01-31
IT1045535B (it)	1980-05-10
FI290974A7 (it)	1975-04-07
JPS5064442A (it)	1975-05-31
GB1456590A (en)	1976-11-24

Publication	Publication Date	Title
FI58067B (fi)	1980-08-29	Kosmetiska preparat foer utvaertes bruk
EP0129778B1 (en)	1991-09-04	Cell-stimulating composition
US4874791A (en)	1989-10-17	Stimulation of hair growth with aliphatic carboxylic acids
DE69526882T2 (de)	2003-01-02	Esculosid enthaltende Zubereitungen und ihre Verwendung in der Kosmetik und Pharmazie
US6203782B1 (en)	2001-03-20	Method and product for promoting hair growth and treating skin conditions
EP0084341B2 (en)	1997-05-14	Emulsion-type composition for external use
JPH07277939A (ja)	1995-10-24	皮膚外用剤
JP3597210B2 (ja)	2004-12-02	養毛料
US5849309A (en)	1998-12-15	Skin activator with glycosaminoglycan production-accelerating effect
JP2003155218A (ja)	2003-05-27	養育毛組成物
JP2844103B2 (ja)	1999-01-06	皮膚外用剤
JPH09241146A (ja)	1997-09-16	皮膚外用剤
HUP0001137A2 (hu)	2000-09-28	Bőrápoló szer
JPH05186326A (ja)	1993-07-27	皮膚化粧料
KR100348155B1 (ko)	2002-08-09	자연산 상황버섯 추출물을 함유하는 발모제 조성물 및이의 제조방법
JPS63115807A (ja)	1988-05-20	化粧料
US5190758A (en)	1993-03-02	Sebaceous excitosecretory agent
JPH11302131A (ja)	1999-11-02	頭皮頭髪用化粧料
KR102386651B1 (ko)	2022-04-14	티플락스티닌을 유효성분으로 함유하는 탈모 예방 또는 치료용 조성물
JPH10279437A (ja)	1998-10-20	頭髪用化粧料
GB1439403A (en)	1976-06-16	Antiseptic composition
JPH11302133A (ja)	1999-11-02	頭皮頭髪用化粧料
RU2069557C1 (ru)	1996-11-27	Крем для кожи
JP2002179549A (ja)	2002-06-26	皮膚外用剤
JPH0812532A (ja)	1996-01-16	養育毛剤