FI952798L - Antibakteerisia troponisubstituoituja fenyylioksatsolidinoneja - Google Patents

Antibakteerisia troponisubstituoituja fenyylioksatsolidinoneja Download PDF

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Publication number
FI952798L
FI952798L FI952798A FI952798A FI952798L FI 952798 L FI952798 L FI 952798L FI 952798 A FI952798 A FI 952798A FI 952798 A FI952798 A FI 952798A FI 952798 L FI952798 L FI 952798L
Authority
FI
Finland
Prior art keywords
tropone
antibacterial
substituted phenyloxazolidinones
phenyloxazolidinones
substituted
Prior art date
Application number
FI952798A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI952798A0 (fi
FI952798A7 (fi
Inventor
Michael Robert Barbachyn
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FI952798A0 publication Critical patent/FI952798A0/fi
Publication of FI952798A7 publication Critical patent/FI952798A7/fi
Publication of FI952798L publication Critical patent/FI952798L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI952798A 1992-12-08 1993-10-14 Antibakteerisia troponisubstituoituja fenyylioksatsolidinoneja FI952798L (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US98858992A 1992-12-08 1992-12-08
US377893A 1993-01-13 1993-01-13
US6635693A 1993-05-21 1993-05-21
PCT/US1993/009589 WO1994013649A1 (en) 1992-12-08 1993-10-14 Tropone-substituted phenyloxazolidinone antibacterial agents

Publications (3)

Publication Number Publication Date
FI952798A0 FI952798A0 (fi) 1995-06-07
FI952798A7 FI952798A7 (fi) 1995-06-07
FI952798L true FI952798L (fi) 1995-06-07

Family

ID=27357482

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952798A FI952798L (fi) 1992-12-08 1993-10-14 Antibakteerisia troponisubstituoituja fenyylioksatsolidinoneja

Country Status (20)

Country Link
US (1) US5523403A (cs)
EP (1) EP0673370B1 (cs)
JP (1) JP3558088B2 (cs)
KR (1) KR100276382B1 (cs)
AT (1) ATE161833T1 (cs)
AU (1) AU670842B2 (cs)
CA (1) CA2147753C (cs)
CZ (1) CZ288788B6 (cs)
DE (1) DE69316240T2 (cs)
DK (1) DK0673370T3 (cs)
ES (1) ES2111188T3 (cs)
FI (1) FI952798L (cs)
GR (1) GR3026228T3 (cs)
HU (1) HUT74099A (cs)
NO (1) NO952253L (cs)
NZ (1) NZ257031A (cs)
PL (1) PL175782B1 (cs)
RU (1) RU2119484C1 (cs)
SK (1) SK282453B6 (cs)
WO (1) WO1994013649A1 (cs)

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AU6902096A (en) * 1995-09-15 1997-04-01 Pharmacia & Upjohn Company 5-amidomethyl alpha, beta-saturated and -unsaturated 3-aryl butyrolactone antibacterial agents
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
DE69716925T2 (de) * 1996-08-21 2003-09-11 Pharmacia & Upjohn Co., Kalamazoo Isoxazoline derivate und ihre verwendung als antimikroben
US5998414A (en) * 1996-08-22 1999-12-07 Hoechst Marion Roussel, Inc. Troponyl piperazines as dopamine D4 receptor ligands
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
EP1772453A1 (en) * 1997-11-07 2007-04-11 Pharmacia & Upjohn Company LLC Process to produce Oxazolidinones
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US6083967A (en) * 1997-12-05 2000-07-04 Pharmacia & Upjohn Company S-oxide and S,S-dioxide tetrahydrothiopyran phenyloxazolidinones
BR9907183A (pt) * 1998-01-23 2003-06-10 Versicor Inc Colet neas combinatórias de oxazolidinona, composições e processos de preparação
WO1999064417A2 (en) 1998-06-05 1999-12-16 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
EP1147422A1 (en) 1999-01-27 2001-10-24 Pharmacia & Upjohn Company Assays for modulators of "elongation factor p" activity
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
US6689769B2 (en) 2000-12-21 2004-02-10 Pharmacia & Upjohn Company Antimicrobial quinolone derivatives and use of the same to treat bacterial infections
ATE304536T1 (de) * 2001-04-17 2005-09-15 Merck & Co Inc Bicyclo(3,1,0)hexan als strukturelement enthaltende oxazolidinon-antibiotika und deren derivate
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
JP2005519931A (ja) 2002-02-05 2005-07-07 ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー 細菌感染症治療に有用な抗微生物性チアジアジノン誘導体
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
EP1490059A1 (en) * 2002-03-29 2004-12-29 Pharmacia & Upjohn Company LLC Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
ATE344036T1 (de) * 2002-11-21 2006-11-15 Pharmacia & Upjohn Co Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5- carbonsäureamid-derivate und verwandte verbindungen als antibakterielle mittel
US8050281B2 (en) * 2003-01-31 2011-11-01 Qwest Communications International Inc. Alert gateway, systems and methods
US7474742B2 (en) * 2003-01-31 2009-01-06 Qwest Communications International Inc. Environmentally-controlled network interface device and methods
US8813142B2 (en) * 2003-01-31 2014-08-19 Qwest Communications International Inc. Methods, systems and apparatus for providing video transmissions over multiple media
BRPI0407252A (pt) * 2003-02-07 2006-01-31 Warner Lambert Co Agentes antibacterianos.
US20040204463A1 (en) * 2003-04-01 2004-10-14 Harris Christina Renee N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
EP1656370B1 (en) * 2003-06-03 2012-08-15 Rib-X Pharmaceuticals, Inc. Biaryl heterocyclic compounds and methods of making and using the same
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
AU2004256086B2 (en) * 2003-07-02 2007-12-06 Kyorin Pharmaceutical Co., Ltd. Oxazolidinone antibiotics and derivatives thereof
ATE471937T1 (de) 2003-07-02 2010-07-15 Merck Sharp & Dohme Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon
US20070185132A1 (en) * 2003-07-02 2007-08-09 Yasumichi Fukuda Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereo
CA2529292A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
MXPA06002188A (es) * 2003-08-25 2006-04-27 Warner Lambert Co Nuevos compuestos antimicrobianos de ariloxazolidinona.
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
AR046782A1 (es) * 2003-12-17 2005-12-21 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo halogenados, composiciones farmaceuticas que los contienen, metodos para su elaboracion y su uso como medicamentos.
KR100854211B1 (ko) * 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
JP5534497B2 (ja) 2005-06-08 2014-07-02 メリンタ セラピューティクス，インコーポレイテッド トリアゾール類の合成方法
KR20080110877A (ko) 2006-03-31 2008-12-19 재단법인 이쯔우 연구소 헤테로환을 갖는 신규 화합물
JPWO2007116960A1 (ja) * 2006-04-06 2009-08-20 財団法人乙卯研究所 炭素環を有するオキサゾリジノン誘導体
CN101883768A (zh) * 2007-10-02 2010-11-10 财团法人乙卯研究所 具有7元杂环的噁唑烷酮衍生物
RU2659792C1 (ru) 2008-10-10 2018-07-04 Мерк Шарп Энд Домэ Корп. Оксазолидиноны и способ их очистки
MY156354A (en) 2009-02-03 2016-02-15 Merck Sharp & Dohme Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) * 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use
WO2025134688A1 (ja) * 2023-12-22 2025-06-26 東亞合成株式会社 トロポロン誘導体

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LU80081A1 (fr) * 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
US4128654A (en) * 1978-02-10 1978-12-05 E. I. Du Pont De Nemours And Company 5-Halomethyl-3-phenyl-2-oxazolidinones
US4340606A (en) * 1980-10-23 1982-07-20 E. I. Du Pont De Nemours And Company 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
DE3149608A1 (de) * 1981-12-15 1983-08-04 Dr. Madaus & Co, 5000 Köln Substituierte tropolone, verfahren zur herstellung derselben und diese enthaltende pharmazeutische zubereitungen
US4461773A (en) * 1982-09-15 1984-07-24 E. I. Dupont De Nemours And Company P-Oxooxazolidinylbenzene compounds as antibacterial agents
ES533097A0 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
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Also Published As

Publication number Publication date
CA2147753C (en) 2004-08-03
RU2119484C1 (ru) 1998-09-27
DK0673370T3 (da) 1998-09-07
CZ288788B6 (cs) 2001-09-12
ATE161833T1 (de) 1998-01-15
EP0673370B1 (en) 1998-01-07
ES2111188T3 (es) 1998-03-01
RU95114378A (ru) 1997-06-10
CZ136695A3 (en) 1995-10-18
FI952798A0 (fi) 1995-06-07
PL309283A1 (en) 1995-10-02
AU670842B2 (en) 1996-08-01
NZ257031A (en) 1996-07-26
FI952798A7 (fi) 1995-06-07
HUT74099A (en) 1996-11-28
WO1994013649A1 (en) 1994-06-23
KR100276382B1 (ko) 2000-12-15
DE69316240T2 (de) 1998-05-20
EP0673370A1 (en) 1995-09-27
GR3026228T3 (en) 1998-05-29
HU9501670D0 (en) 1995-08-28
AU5323994A (en) 1994-07-04
CA2147753A1 (en) 1994-06-23
JP3558088B2 (ja) 2004-08-25
NO952253L (no) 1995-08-08
US5523403A (en) 1996-06-04
DE69316240D1 (de) 1998-02-12
NO952253D0 (no) 1995-06-07
SK282453B6 (sk) 2002-02-05
PL175782B1 (pl) 1999-02-26
SK74695A3 (en) 1995-10-11
JPH08504205A (ja) 1996-05-07

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Legal Events

Date Code Title Description
HC Name/ company changed in application

Owner name: PHARMACIA & UPJOHN COMPANY

MA Patent expired