NO20055695L - Tiadiazinforbindelser og anvendelse derav som positive AMPA-reseptormodulatorer - Google Patents
Tiadiazinforbindelser og anvendelse derav som positive AMPA-reseptormodulatorerInfo
- Publication number
- NO20055695L NO20055695L NO20055695A NO20055695A NO20055695L NO 20055695 L NO20055695 L NO 20055695L NO 20055695 A NO20055695 A NO 20055695A NO 20055695 A NO20055695 A NO 20055695A NO 20055695 L NO20055695 L NO 20055695L
- Authority
- NO
- Norway
- Prior art keywords
- branched
- linear
- compounds
- alkyl group
- hydrogen atom
- Prior art date
Links
- 102000003678 AMPA Receptors Human genes 0.000 title abstract 2
- 108090000078 AMPA Receptors Proteins 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 abstract 1
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical compound C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- ZLTPDFXIESTBQG-UHFFFAOYSA-N isothiazole Chemical compound C=1C=NSC=1 ZLTPDFXIESTBQG-UHFFFAOYSA-N 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- YYMWVZQRBNARFZ-UHFFFAOYSA-M sodium;2-[2,3-bis(sulfanyl)propoxy]ethanesulfonate Chemical compound [Na+].[O-]S(=O)(=O)CCOCC(S)CS YYMWVZQRBNARFZ-UHFFFAOYSA-M 0.000 abstract 1
- 150000008334 thiadiazines Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0305448A FR2854634B1 (fr) | 2003-05-05 | 2003-05-05 | Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR2004/001070 WO2004099217A1 (fr) | 2003-05-05 | 2004-05-04 | Derives de thiadiazine et leur utilisation comme modulateurs positifs des recepteurs ampa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20055695L true NO20055695L (no) | 2005-12-01 |
Family
ID=33306157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20055695A NO20055695L (no) | 2003-05-05 | 2005-12-01 | Tiadiazinforbindelser og anvendelse derav som positive AMPA-reseptormodulatorer |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7476668B2 (fr) |
| EP (1) | EP1620441A1 (fr) |
| JP (1) | JP4461139B2 (fr) |
| KR (1) | KR100741235B1 (fr) |
| CN (1) | CN100363368C (fr) |
| AR (1) | AR044245A1 (fr) |
| AU (1) | AU2004236005B2 (fr) |
| BR (1) | BRPI0410002A (fr) |
| CA (1) | CA2524377C (fr) |
| EA (1) | EA009240B1 (fr) |
| FR (1) | FR2854634B1 (fr) |
| GE (1) | GEP20084318B (fr) |
| MA (1) | MA27732A1 (fr) |
| MX (1) | MXPA05011823A (fr) |
| MY (1) | MY136694A (fr) |
| NO (1) | NO20055695L (fr) |
| NZ (1) | NZ543214A (fr) |
| UA (1) | UA80046C2 (fr) |
| WO (1) | WO2004099217A1 (fr) |
| ZA (1) | ZA200508660B (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008510835A (ja) | 2004-08-25 | 2008-04-10 | エッセンシャリス，インク． | カリウムａｔｐチャンネル開放因子の製剤処方、及びその使用 |
| WO2007081521A2 (fr) | 2006-01-05 | 2007-07-19 | Essentialis, Inc. | Sels d'ouvreurs des canaux potassiques atp-dépendants et leurs utilisations |
| US20110218190A1 (en) * | 2008-11-10 | 2011-09-08 | The Regents Of The University Of California | Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction |
| WO2012020848A1 (fr) * | 2010-08-10 | 2012-02-16 | Takeda Pharmaceutical Company Limited | Composé hétérocyclique et son utilisation |
| JP5901365B2 (ja) * | 2012-03-12 | 2016-04-06 | 株式会社トクヤマ | イミダート化合物の製造方法 |
| EP3311842A1 (fr) | 2013-06-13 | 2018-04-25 | VeroScience LLC | Compositions et procédés de traitement des troubles métaboliques |
| PL3321252T3 (pl) | 2015-07-06 | 2021-04-06 | Public University Corporation Yokohama City University | Nowy związek, który specyficznie wiąże się z receptorem AMPA |
| EP3436021B1 (fr) | 2016-03-29 | 2026-07-29 | RespireRx Pharmaceuticals, Inc. | Compositions comprenant des ampakines a faible impact pour traiter des troubles de déficit de l'attention |
| JP6241974B1 (ja) | 2017-01-11 | 2017-12-06 | 公立大学法人横浜市立大学 | 霊長類生体の脳内ａｍｐａ受容体のイメージング方法、プログラム、及びスクリーニング方法 |
| US10680583B1 (en) * | 2019-02-26 | 2020-06-09 | Xilinx, Inc. | Control circuit for and method of controlling an operation of an integrated circuit device |
| TWI873185B (zh) | 2019-09-16 | 2025-02-21 | 日商武田藥品工業股份有限公司 | 唑稠合之嗒-3(2h)-酮衍生物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3733409A (en) * | 1969-05-20 | 1973-05-15 | Schering Corp | Method of treating hypertension using thieno (1,2,4) thiadiazines |
| AU4345297A (en) * | 1996-09-17 | 1998-04-14 | Regents Of The University Of California, The | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
| AU757693B2 (en) * | 1997-07-16 | 2003-03-06 | Novo Nordisk A/S | Fused 1,2,4-thiadiazine derivatives, their preparation and use |
| RU2214405C2 (ru) * | 1998-02-18 | 2003-10-20 | НьюроСёрч А/С | Новые соединения и их применение в качестве положительных модуляторов амра-рецепторов |
| FR2801587B1 (fr) * | 1999-11-30 | 2002-01-11 | Adir | Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2003
- 2003-05-05 FR FR0305448A patent/FR2854634B1/fr not_active Expired - Fee Related
-
2004
- 2004-04-05 UA UAA200511454A patent/UA80046C2/uk unknown
- 2004-04-30 MY MYPI20041647A patent/MY136694A/en unknown
- 2004-05-04 KR KR1020057020817A patent/KR100741235B1/ko not_active Expired - Fee Related
- 2004-05-04 BR BRPI0410002-6A patent/BRPI0410002A/pt not_active IP Right Cessation
- 2004-05-04 EA EA200501696A patent/EA009240B1/ru not_active IP Right Cessation
- 2004-05-04 AR ARP040101515A patent/AR044245A1/es unknown
- 2004-05-04 US US10/555,743 patent/US7476668B2/en not_active Expired - Fee Related
- 2004-05-04 WO PCT/FR2004/001070 patent/WO2004099217A1/fr not_active Ceased
- 2004-05-04 CN CNB200480014886XA patent/CN100363368C/zh not_active Expired - Fee Related
- 2004-05-04 GE GEAP20049092A patent/GEP20084318B/en unknown
- 2004-05-04 CA CA2524377A patent/CA2524377C/fr not_active Expired - Fee Related
- 2004-05-04 AU AU2004236005A patent/AU2004236005B2/en not_active Ceased
- 2004-05-04 JP JP2006505830A patent/JP4461139B2/ja not_active Expired - Fee Related
- 2004-05-04 EP EP04742632A patent/EP1620441A1/fr not_active Withdrawn
- 2004-05-04 NZ NZ543214A patent/NZ543214A/en not_active IP Right Cessation
- 2004-05-04 MX MXPA05011823A patent/MXPA05011823A/es active IP Right Grant
- 2004-05-04 ZA ZA200508660A patent/ZA200508660B/en unknown
-
2005
- 2005-10-21 MA MA28567A patent/MA27732A1/fr unknown
- 2005-12-01 NO NO20055695A patent/NO20055695L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MY136694A (en) | 2008-11-28 |
| FR2854634A1 (fr) | 2004-11-12 |
| BRPI0410002A (pt) | 2006-04-25 |
| CA2524377C (fr) | 2010-08-24 |
| JP4461139B2 (ja) | 2010-05-12 |
| US7476668B2 (en) | 2009-01-13 |
| AU2004236005A1 (en) | 2004-11-18 |
| AR044245A1 (es) | 2005-09-07 |
| EP1620441A1 (fr) | 2006-02-01 |
| UA80046C2 (en) | 2007-08-10 |
| GEP20084318B (en) | 2008-03-10 |
| MA27732A1 (fr) | 2006-01-02 |
| KR100741235B1 (ko) | 2007-07-19 |
| EA009240B1 (ru) | 2007-12-28 |
| JP2006525292A (ja) | 2006-11-09 |
| US20070004709A1 (en) | 2007-01-04 |
| ZA200508660B (en) | 2007-01-31 |
| CN100363368C (zh) | 2008-01-23 |
| AU2004236005B2 (en) | 2010-01-21 |
| NZ543214A (en) | 2009-02-28 |
| HK1088327A1 (en) | 2006-11-03 |
| MXPA05011823A (es) | 2006-05-25 |
| EA200501696A1 (ru) | 2006-06-30 |
| FR2854634B1 (fr) | 2005-07-08 |
| KR20060006830A (ko) | 2006-01-19 |
| CA2524377A1 (fr) | 2004-11-18 |
| WO2004099217A1 (fr) | 2004-11-18 |
| CN1798750A (zh) | 2006-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |