GR3025857T3 - Molecular cloning and expression of human IL-3 - Google Patents

Molecular cloning and expression of human IL-3

Info

Publication number
GR3025857T3
GR3025857T3 GR980400027T GR980400027T GR3025857T3 GR 3025857 T3 GR3025857 T3 GR 3025857T3 GR 980400027 T GR980400027 T GR 980400027T GR 980400027 T GR980400027 T GR 980400027T GR 3025857 T3 GR3025857 T3 GR 3025857T3
Authority
GR
Greece
Prior art keywords
hil
expression
human
molecular cloning
produced
Prior art date
Application number
GR980400027T
Other languages
Greek (el)
English (en)
Inventor
Lambertus Christiaan Dorssers
Gerard Dr Wagemaker
Yvonne Johanna Vos
Leen Robert Willem Van
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of GR3025857T3 publication Critical patent/GR3025857T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR980400027T 1986-12-16 1998-01-08 Molecular cloning and expression of human IL-3 GR3025857T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP86202285 1986-12-16
EP87201322 1987-07-13

Publications (1)

Publication Number Publication Date
GR3025857T3 true GR3025857T3 (en) 1998-04-30

Family

ID=26103432

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400027T GR3025857T3 (en) 1986-12-16 1998-01-08 Molecular cloning and expression of human IL-3

Country Status (14)

Country Link
JP (2) JPH01502157A (de)
AT (1) ATE161882T1 (de)
AU (1) AU617095B2 (de)
CA (1) CA1341503C (de)
DE (1) DE3752158T2 (de)
ES (1) ES2113338T3 (de)
FI (1) FI102293B1 (de)
GR (1) GR3025857T3 (de)
IE (1) IE81129B1 (de)
IL (1) IL84852A (de)
NO (1) NO180544C (de)
NZ (1) NZ222939A (de)
PT (1) PT86381B (de)
WO (1) WO1988004691A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors
US6238889B1 (en) 1986-12-16 2001-05-29 Dsm N.V. Molecular cloning and expression of the Pro8 isoform of human IL-3
OA09736A (en) * 1987-02-18 1993-11-30 Schering Biotech Corp "Human interleukin-3 and muteins thereof".
US5304637A (en) * 1987-07-13 1994-04-19 Gist-Brocades N.V. Expression and purification of human interleukin-3 and muteins thereof
GB2210883B (en) * 1987-10-08 1992-01-02 British Bio Technology Synthetic interleukin-3 gene
US6384194B1 (en) 1987-12-16 2002-05-07 Dsm N.V. Expression and purification of human interleukin-3 and muteins thereof
JPH04500508A (ja) * 1988-07-20 1992-01-30 イミュネックス・コーポレーション 非グリコシル化　ヒト　インターロイキン―３　組成物
NZ232913A (en) * 1989-03-15 1992-08-26 Gist Brocades Nv Il-3 produced recombinantly and purified to homogeneity; vectors and pharmaceutical preparations
US5128450A (en) * 1989-06-30 1992-07-07 Urdal David L Nonglycosylated human interleukin-3 analog proteins
EP0413383B1 (de) 1989-08-14 1997-06-18 Gist-Brocades N.V. Mutanten von Interleukin-3
US5516512A (en) 1989-08-14 1996-05-14 Gist-Brocades, N.V. N- and C-terminal truncation and deletion mutants of human interleukin-3
DK0596881T3 (da) * 1991-08-01 1997-10-13 Fond Nat Transfusion Sanguine Ekspression i ikke-tumurale humane lymofoblastoider med en integrativ vektor
ATE238421T1 (de) * 1992-11-24 2003-05-15 Searle & Co Interleukin-3 (il-3)-polypeptide mith mehreren mutationen
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US5501962A (en) * 1993-06-21 1996-03-26 G. D. Searle & Co. Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US6017523A (en) * 1995-06-06 2000-01-25 G.D. Searle & Co. Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
WO1999041382A2 (en) * 1998-02-17 1999-08-19 Hyseq, Inc. A novel interleukin-3 and uses thereof
JP2008527981A (ja) * 2005-01-25 2008-07-31 アポロ ライフ サイエンシズ リミテッド 治療目的および診断目的のためにパラメーターにより選択されたｇｍ−ｃｓｆ、ｉｌ−３、ｉｌ−４、ｉｌ−５、ならびにそのキメラ
EP2001905A1 (de) * 2006-04-03 2008-12-17 New England Biolabs, Inc. Expression, sekretion und reinigung von rekombinantem rinderserumalbumin (rbsa) und dessen verwendung
WO2024033522A1 (en) 2022-08-11 2024-02-15 Universitätsklinikum Regensburg Antibodies targeting il3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695542A (en) * 1983-10-04 1987-09-22 Dnax Research Institute Of Molecular And Cellular Biology, Inc. cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
AU570762B2 (en) * 1983-12-23 1988-03-24 Australian National University, The Cloning of cdna for il-3
GR871029B (en) * 1986-07-14 1987-11-02 Genetics Inst Novel osteoinductive factors

Also Published As

Publication number Publication date
JPH01502157A (ja) 1989-08-03
NO883614L (no) 1988-08-12
NO883614D0 (no) 1988-08-12
WO1988004691A1 (en) 1988-06-30
DE3752158D1 (de) 1998-02-12
FI102293B (fi) 1998-11-13
NZ222939A (en) 1991-03-26
PT86381B (pt) 1990-11-20
IL84852A (en) 1994-06-24
FI102293B1 (fi) 1998-11-13
JPH1080286A (ja) 1998-03-31
ES2113338T3 (es) 1998-05-01
AU617095B2 (en) 1991-11-21
FI883688L (fi) 1988-08-08
IL84852A0 (en) 1988-06-30
AU1057788A (en) 1988-07-15
IE81129B1 (en) 2000-03-22
ATE161882T1 (de) 1998-01-15
IE873409L (en) 1988-06-12
CA1341503C (en) 2006-04-04
NO180544C (no) 1997-05-07
DE3752158T2 (de) 1998-05-20
PT86381A (en) 1988-01-01
FI883688A0 (fi) 1988-08-08
NO180544B (no) 1997-01-27

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