HRP20040170A2 - Combination therapy for the treatment of cancer - Google Patents

Combination therapy for the treatment of cancer Download PDF

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Publication number
HRP20040170A2
HRP20040170A2 HR20040170A HRP20040170A HRP20040170A2 HR P20040170 A2 HRP20040170 A2 HR P20040170A2 HR 20040170 A HR20040170 A HR 20040170A HR P20040170 A HRP20040170 A HR P20040170A HR P20040170 A2 HRP20040170 A2 HR P20040170A2
Authority
HR
Croatia
Prior art keywords
group
hydrogen
carboxylic acid
alkyl
trifluoromethyl
Prior art date
Application number
HR20040170A
Other languages
English (en)
Croatian (hr)
Inventor
Jaime Masferrer
Parul Doshi
Julie Cherrington
Original Assignee
Sugen
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen, Pharmacia Corp filed Critical Sugen
Publication of HRP20040170A2 publication Critical patent/HRP20040170A2/hr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
HR20040170A 2001-08-15 2002-08-15 Combination therapy for the treatment of cancer HRP20040170A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31241301P 2001-08-15 2001-08-15
PCT/US2002/025797 WO2003015608A2 (en) 2001-08-15 2002-08-15 Combination therapy for the treatment of cancer

Publications (1)

Publication Number Publication Date
HRP20040170A2 true HRP20040170A2 (en) 2004-08-31

Family

ID=23211320

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040170A HRP20040170A2 (en) 2001-08-15 2002-08-15 Combination therapy for the treatment of cancer

Country Status (36)

Country Link
US (1) US7320996B2 (pl)
EP (1) EP1427326B1 (pl)
JP (1) JP2005501843A (pl)
KR (1) KR100656004B1 (pl)
CN (1) CN1541098A (pl)
AP (1) AP2004002995A0 (pl)
AR (1) AR038957A1 (pl)
AT (1) ATE414512T1 (pl)
AU (1) AU2002329744B2 (pl)
BG (1) BG108622A (pl)
BR (1) BR0211978A (pl)
CA (1) CA2457745A1 (pl)
CO (1) CO5560544A2 (pl)
CZ (1) CZ2004356A3 (pl)
DE (1) DE60229959D1 (pl)
EA (1) EA008137B1 (pl)
EC (1) ECSP045021A (pl)
GE (1) GEP20063868B (pl)
HR (1) HRP20040170A2 (pl)
HU (1) HUP0500424A3 (pl)
IL (1) IL159887A0 (pl)
IS (1) IS7137A (pl)
MA (1) MA27060A1 (pl)
MX (1) MXPA04001464A (pl)
NO (1) NO20040516L (pl)
NZ (1) NZ530792A (pl)
OA (1) OA12651A (pl)
PE (1) PE20030332A1 (pl)
PL (1) PL368921A1 (pl)
RS (1) RS13204A (pl)
SK (1) SK1412004A3 (pl)
TN (1) TNSN04015A1 (pl)
TW (1) TWI230609B (pl)
UA (1) UA77002C2 (pl)
WO (1) WO2003015608A2 (pl)
ZA (1) ZA200400849B (pl)

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WO2005118543A1 (ja) * 2004-06-03 2005-12-15 Ono Pharmaceutical Co., Ltd. キナーゼ阻害薬およびその用途
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KR20080045678A (ko) * 2005-07-08 2008-05-23 존 피. 포드 전신성 항암 치료용 계량-투여량 및 안전 및 순응 패키징
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WO2009030270A1 (en) * 2007-09-03 2009-03-12 Novartis Ag Dihydroindole derivatives useful in parkinson's disease
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RU2495628C1 (ru) * 2012-04-18 2013-10-20 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Способ выбора тактики лечения актинического кератоза
TWI646091B (zh) * 2012-12-28 2019-01-01 日商衛斯克慧特股份有限公司 鹽類及晶形
HK1220184A1 (zh) * 2013-03-13 2017-04-28 Boston Biomedical, Inc. 用於治疗癌症的作为癌症干细胞途径激酶抑制剂的3-(芳基或杂芳基)甲基吲哚-2-酮衍生物
CN103923014A (zh) * 2014-05-05 2014-07-16 宁夏宝马药业有限公司 环肌酸制备方法
JP6942726B2 (ja) 2016-01-08 2021-09-29 ユークリセス ファーマシューティカルズ，インコーポレイテッド クロメン化合物および第２活性薬剤の併用薬
CN111759883B (zh) * 2020-07-23 2021-09-17 浙江农林大学 山核桃内果皮提取物在制备抗卵巢癌产品中的应用
CN114853736B (zh) * 2022-07-06 2022-10-21 北京鑫开元医药科技有限公司 具有trk抑制活性的化合物、制备方法、组合物及其用途

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