HRP20100521T1 - Monoklonska antitijela protiv čimbenika rasta hepatocita - Google Patents
Monoklonska antitijela protiv čimbenika rasta hepatocita Download PDFInfo
- Publication number
- HRP20100521T1 HRP20100521T1 HR20100521T HRP20100521T HRP20100521T1 HR P20100521 T1 HRP20100521 T1 HR P20100521T1 HR 20100521 T HR20100521 T HR 20100521T HR P20100521 T HRP20100521 T HR P20100521T HR P20100521 T1 HRP20100521 T1 HR P20100521T1
- Authority
- HR
- Croatia
- Prior art keywords
- hgf
- monoclonal antibody
- mab
- inhibits
- binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/825,060 US20040208876A1 (en) | 2003-04-18 | 2004-04-15 | Monoclonal antibodies to hepatocyte growth factor |
| PCT/US2004/026565 WO2005107800A1 (en) | 2004-04-15 | 2004-08-13 | Monoclonal antibodies to hepatocyte growth factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100521T1 true HRP20100521T1 (hr) | 2010-10-31 |
Family
ID=35320045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100521T HRP20100521T1 (hr) | 2004-04-15 | 2004-08-13 | Monoklonska antitijela protiv čimbenika rasta hepatocita |
Country Status (25)
| Country | Link |
|---|---|
| US (5) | US20040208876A1 (de) |
| EP (2) | EP1734995B1 (de) |
| JP (2) | JP4594381B2 (de) |
| KR (1) | KR101072736B1 (de) |
| CN (1) | CN1964738A (de) |
| AT (1) | ATE473760T1 (de) |
| AU (1) | AU2004319276C1 (de) |
| BR (1) | BRPI0418745A (de) |
| CA (1) | CA2563080C (de) |
| CR (1) | CR8698A (de) |
| CY (1) | CY1110783T1 (de) |
| DE (1) | DE602004028168D1 (de) |
| DK (1) | DK1734995T3 (de) |
| ES (1) | ES2346886T3 (de) |
| HR (1) | HRP20100521T1 (de) |
| IL (1) | IL178474A (de) |
| MX (1) | MXPA06011822A (de) |
| NO (1) | NO20065227L (de) |
| NZ (1) | NZ550324A (de) |
| PL (1) | PL1734995T3 (de) |
| PT (1) | PT1734995E (de) |
| RU (1) | RU2361879C2 (de) |
| SI (1) | SI1734995T1 (de) |
| WO (1) | WO2005107800A1 (de) |
| ZA (1) | ZA200609407B (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
| KR101254371B1 (ko) * | 2003-07-18 | 2013-05-02 | 암젠 프레몬트 인코포레이티드 | 간세포 성장인자에 결합하는 분리된 항체 |
| EP1773885B1 (de) * | 2004-08-05 | 2010-04-21 | Genentech, Inc. | Humanisierte anti-cmet-antagonisten |
| EP1885400A4 (de) * | 2005-06-02 | 2011-01-26 | Galaxy Biotech Llc | Verfahren zur behandlung von hirntumoren durch antikörper |
| RU2446826C2 (ru) | 2005-10-14 | 2012-04-10 | Фукуока Юниверсити | Агенты для подавления повреждения трансплантированных островков после трансплантации островков |
| AR058135A1 (es) | 2005-10-21 | 2008-01-23 | Chugai Pharmaceutical Co Ltd | Agentes para el tratamiento de cardiopatias |
| AR057582A1 (es) | 2005-11-15 | 2007-12-05 | Nat Hospital Organization | Agentes para suprimir la induccion de linfocitos t citotoxicos |
| TW200803894A (en) * | 2005-11-25 | 2008-01-16 | Univ Keio | Prostate cancer therapeutic agents |
| CA2637917C (en) | 2006-01-27 | 2015-11-24 | Keio University | Therapeutic agents for diseases involving choroidal neovascularization |
| AR059922A1 (es) * | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
| EP2025346B1 (de) | 2006-04-07 | 2016-08-10 | Osaka University | Mittel zur förderung der muskelregeneration |
| AR061171A1 (es) | 2006-06-02 | 2008-08-06 | Aveo Pharmaceuticals Inc | Proteinas de union al factor de crecimiento de hepatocitos (fch) |
| AR061170A1 (es) | 2006-06-02 | 2008-08-06 | Aveo Pharmaceuticals Inc | Proteinas que se unen con el factor de crecimiento de hepatocitos (hgf) |
| WO2008090901A1 (ja) | 2007-01-23 | 2008-07-31 | Shinshu University | 慢性拒絶反応抑制剤 |
| EP2170268A2 (de) * | 2007-06-25 | 2010-04-07 | Amgen, Inc. | Zusammensetzungen von spezifischen bindungsmitteln für den hepatozyten-wachstumsfaktor |
| CL2009000843A1 (es) * | 2008-04-11 | 2009-07-24 | Galaxy Biotech Llc | Metodo para tratar cancer en un paciente que comprende la administracion de un primer agente que es inhibidor de factor de crecimiento de hepatocito (hgf) en combinacion con un segundo agente que es inhibidor de una ruta de senalizacion celular diferente de la ruta hgf/cmet. |
| EP2288383A1 (de) * | 2008-05-14 | 2011-03-02 | Amgen, Inc | Kombinationen von vegf(r)-inhibitoren und hepatozyten-wachstumsfaktor (c-met)-inhibitoren zur behandlung von krebs |
| TWI528973B (zh) | 2008-06-05 | 2016-04-11 | Chugai Pharmaceutical Co Ltd | Nerve infiltration inhibitor |
| PA8849001A1 (es) | 2008-11-21 | 2010-06-28 | Lilly Co Eli | Anticuerpos de c-met |
| US8545839B2 (en) * | 2008-12-02 | 2013-10-01 | Pierre Fabre Medicament | Anti-c-Met antibody |
| US20120052064A1 (en) * | 2009-04-17 | 2012-03-01 | Yuuki Ito | Anti-hgf antibody combinational cancer therapies |
| CN101555912B (zh) * | 2009-04-29 | 2012-10-03 | 深圳市特辰科技股份有限公司 | 一种转轮式自锁安全制动装置及其工作方法 |
| EP2287197A1 (de) * | 2009-08-21 | 2011-02-23 | Pierre Fabre Medicament | Anti-cMET-Antikörper und seine Verwendung zur Erkennung und Diagnose von Krebs |
| JP6051049B2 (ja) | 2010-05-28 | 2016-12-21 | 中外製薬株式会社 | 抗腫瘍t細胞応答増強剤 |
| US20130315895A1 (en) | 2010-07-01 | 2013-11-28 | Takeda Pharmaceutical Company Limited | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET |
| EP2621483A1 (de) | 2010-09-27 | 2013-08-07 | Exelixis, Inc. | Met- und vegf-doppelinhibitoren zur behandlung von kastrationsresistentem prostatakrebs und osteoblastischen knochenmetastasen |
| RU2013155695A (ru) | 2011-06-30 | 2015-08-10 | Дженентек, Инк. | Препараты антител против с-мет |
| CZ2011514A3 (cs) * | 2011-08-19 | 2013-01-23 | Invos, Spol. S R. O. | Biokontejner pro sber bioodpadu a komunálního odpadu |
| CN103974720A (zh) | 2011-09-09 | 2014-08-06 | 安姆根有限公司 | C-met蛋白质用于预测抗肝细胞生长因子(“hgf”)抗体在食管癌和胃癌患者中的功效的用途 |
| CA2843771A1 (en) | 2011-09-20 | 2013-03-28 | Eli Lilly And Company | Anti-c-met antibodies |
| EP2873422A4 (de) | 2012-07-10 | 2015-12-30 | Takeda Pharmaceutical | Pharmazeutische zubereitung zur injektion |
| EP2708556B1 (de) | 2012-09-12 | 2018-11-07 | Samsung Electronics Co., Ltd | Pharmazeutische zusammensetzung zur verwendung in einer kombinationstherapie zur prävention oder behandlung von c-met- oder angiogenesefaktorinduzierten erkrankungen |
| KR20150140685A (ko) * | 2013-03-14 | 2015-12-16 | 앨더 바이오파마슈티컬즈, 인코포레이티드 | Hgf에 대한 항체 및 이를 포함하는 조성물 |
| US9481725B2 (en) | 2013-03-14 | 2016-11-01 | Alderbio Holdings, Llc | Antibodies to HGF and compositions containing |
| WO2015031578A1 (en) * | 2013-08-28 | 2015-03-05 | Abbvie Inc. | Hgf assay |
| EP3620531A4 (de) | 2017-05-02 | 2021-03-17 | National Center of Neurology and Psychiatry | Verfahren zur vorhersage und beurteilung der therapeutischen wirkung bei erkrankungen im zusammenhang mit il-6 und neutrophilen |
| EP3698808B1 (de) | 2017-10-20 | 2025-01-01 | Hyogo College Of Medicine | Anti-il-6 rezeptorantikörper enthaltende medizinische zusammensetzung zur verhinderung von postoperativer adhäsion |
| WO2019151418A1 (ja) | 2018-01-31 | 2019-08-08 | 元一 加藤 | Il-6阻害剤を含有する喘息の治療剤 |
| IL287220B2 (en) | 2019-04-17 | 2026-03-01 | Univ Hiroshima | A therapeutic agent for urological cancer characterized by administering an IL-6 inhibitor in combination with a CCR2 inhibitor |
| CN121358764A (zh) * | 2023-05-05 | 2026-01-16 | 布坦坦研究所 | 人抗FGF2单克隆抗体(mAb)、包含其的药物组合物、其用途和用于检测包含所述mAb的生物样品中的癌症的试剂盒 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US722041A (en) * | 1902-11-24 | 1903-03-03 | Mail Belting Company | Conveyer-belt. |
| JP2564486B2 (ja) | 1986-07-14 | 1996-12-18 | 修治 橋本 | 肝細胞増殖因子 |
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP1690934A3 (de) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Bildung von xenogenen Antikörpern |
| GB9003621D0 (en) | 1990-02-16 | 1990-04-11 | Imp Cancer Res Tech | Protein factor |
| GB9009548D0 (en) * | 1990-04-27 | 1990-06-20 | Celltech Ltd | Chimeric antibody and method |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| EP0585287B1 (de) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Verfahren zur herstellung von spezifischen bindungspaargliedern |
| GB9110202D0 (en) * | 1991-05-10 | 1991-07-03 | Erba Carlo Spa | Truncated forms of the hepatocyte growth factor(hgf)receptor |
| EP1400536A1 (de) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Verfahren zur Herstellung humanisierter Antikörper |
| CA2124967C (en) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| US6498144B1 (en) | 1993-10-18 | 2002-12-24 | North Shore - Long Island Jewish Research Institute | Use of scatter factor to enhance angiogenesis |
| US5837676A (en) | 1993-10-18 | 1998-11-17 | Long Island Jewish Medical Center | Use of scatter factor to enhance angiogenesis |
| US5707624A (en) | 1994-06-03 | 1998-01-13 | The Regents Of The University Of Michigan | Treatment of Kaposi's sarcoma by inhibition of scatter factor |
| US5646036A (en) | 1995-06-02 | 1997-07-08 | Genentech, Inc. | Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies |
| US6214344B1 (en) * | 1995-06-02 | 2001-04-10 | Genetech, Inc. | Hepatocyte growth factor receptor antagonists and uses thereof |
| US5686292A (en) * | 1995-06-02 | 1997-11-11 | Genentech, Inc. | Hepatocyte growth factor receptor antagonist antibodies and uses thereof |
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| IL127558A0 (en) * | 1996-07-03 | 1999-10-28 | Genentech Inc | Hepatocyte growth factor receptor agonists and uses thereof |
| AU5588099A (en) | 1998-08-28 | 2000-03-21 | Dendreon Corporation | Selective apoptosis of neoplastic cells by an hla-dr specific monoclonal antibody |
| US7459536B1 (en) | 1999-11-09 | 2008-12-02 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | HGF-SF monoclonal antibody combinations |
| EP1423432A4 (de) | 2001-07-26 | 2006-01-11 | Lilly Co Eli | Interleukin-1-beta-antikörper |
| AU2002357388A1 (en) | 2001-12-27 | 2003-07-24 | The United States Of America, As Represented By The Department Of Veterans Affairs | Monoclonal antibody imaging and therapy of tumors that express met and bind hepatocyte growth factor |
| AU2003270118A1 (en) * | 2002-08-30 | 2004-03-19 | F. Hoffmann-La Roche Ag | Scatter factor/hepatocyte growth factor antagonist nk4 for the treatment of glioma |
| US7220410B2 (en) | 2003-04-18 | 2007-05-22 | Galaxy Biotech, Llc | Monoclonal antibodies to hepatocyte growth factor |
| US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
| MXPA05013181A (es) | 2003-06-06 | 2006-06-23 | Genentech Inc | Metodos y composiciones para modular hgf/met. |
| DE602004024536D1 (de) | 2003-07-07 | 2010-01-21 | Van Andel Res Inst | Hemmung der tumor-angiogenese durch eine kombination von thrombospondin-1 und hemmern des vaskulären endothel-wachstumsfaktors |
| KR101254371B1 (ko) * | 2003-07-18 | 2013-05-02 | 암젠 프레몬트 인코포레이티드 | 간세포 성장인자에 결합하는 분리된 항체 |
| KR100556660B1 (ko) | 2003-11-11 | 2006-03-10 | 국립암센터 | Hgf의 중화가능 에피토프 및 이에 결합하는 중화 항체 |
| EP1885400A4 (de) | 2005-06-02 | 2011-01-26 | Galaxy Biotech Llc | Verfahren zur behandlung von hirntumoren durch antikörper |
| AR059922A1 (es) * | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
-
2004
- 2004-04-15 US US10/825,060 patent/US20040208876A1/en not_active Abandoned
- 2004-08-13 AU AU2004319276A patent/AU2004319276C1/en not_active Ceased
- 2004-08-13 DE DE602004028168T patent/DE602004028168D1/de not_active Expired - Lifetime
- 2004-08-13 NZ NZ550324A patent/NZ550324A/en not_active IP Right Cessation
- 2004-08-13 AT AT04781281T patent/ATE473760T1/de active
- 2004-08-13 MX MXPA06011822A patent/MXPA06011822A/es active IP Right Grant
- 2004-08-13 HR HR20100521T patent/HRP20100521T1/hr unknown
- 2004-08-13 ZA ZA200609407A patent/ZA200609407B/xx unknown
- 2004-08-13 JP JP2007508323A patent/JP4594381B2/ja not_active Expired - Fee Related
- 2004-08-13 KR KR1020067023964A patent/KR101072736B1/ko not_active Expired - Fee Related
- 2004-08-13 EP EP04781281A patent/EP1734995B1/de not_active Expired - Lifetime
- 2004-08-13 WO PCT/US2004/026565 patent/WO2005107800A1/en not_active Ceased
- 2004-08-13 EP EP10160203A patent/EP2204191A1/de not_active Withdrawn
- 2004-08-13 RU RU2006140257/13A patent/RU2361879C2/ru not_active IP Right Cessation
- 2004-08-13 SI SI200431468T patent/SI1734995T1/sl unknown
- 2004-08-13 CN CNA200480042750XA patent/CN1964738A/zh active Pending
- 2004-08-13 PL PL04781281T patent/PL1734995T3/pl unknown
- 2004-08-13 CA CA2563080A patent/CA2563080C/en not_active Expired - Fee Related
- 2004-08-13 PT PT04781281T patent/PT1734995E/pt unknown
- 2004-08-13 DK DK04781281.3T patent/DK1734995T3/da active
- 2004-08-13 ES ES04781281T patent/ES2346886T3/es not_active Expired - Lifetime
- 2004-08-13 BR BRPI0418745-8A patent/BRPI0418745A/pt not_active IP Right Cessation
-
2006
- 2006-10-05 IL IL178474A patent/IL178474A/en not_active IP Right Cessation
- 2006-10-19 CR CR8698A patent/CR8698A/es unknown
- 2006-11-14 NO NO20065227A patent/NO20065227L/no not_active Application Discontinuation
-
2007
- 2007-02-23 US US11/710,009 patent/US7494650B2/en not_active Expired - Fee Related
- 2007-06-13 US US11/818,305 patent/US7687063B2/en not_active Expired - Fee Related
-
2008
- 2008-12-22 US US12/342,059 patent/US20090104192A1/en not_active Abandoned
-
2010
- 2010-08-03 JP JP2010174810A patent/JP2011012067A/ja not_active Withdrawn
- 2010-08-30 CY CY20101100789T patent/CY1110783T1/el unknown
-
2011
- 2011-06-14 US US13/160,444 patent/US20120064066A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20100521T1 (hr) | Monoklonska antitijela protiv čimbenika rasta hepatocita | |
| RU2504551C2 (ru) | Белки, связывающие антиген фактор роста, подобный гепаринсвязывающему эпидермальному фактору роста | |
| HRP20151019T1 (hr) | PROTUTIJELA PROTIV c-MET | |
| HRP20191609T1 (hr) | Protein | |
| UA90457C2 (ru) | Человеческое моноклональное антитело, которое специфически связывается с м-csf человека и блокирует связывание м-csf с с-fms | |
| RU2007133108A (ru) | АНТИТЕЛА, СВЯЗЫВАЮЩИЕСЯ С EphA2, И МЕТОДЫ ИХ ИСПОЛЬЗОВАНИЯ | |
| MY145042A (en) | Humanized monoclonal antibodies to hepatocyte growth factor | |
| HK1221153A1 (zh) | 抗体-药物缀合物 | |
| NZ712762A (en) | Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r | |
| JP2017512765A5 (de) | ||
| UA89350C2 (uk) | Гуманізоване антитіло, що зв'язує людський cd20 | |
| JP2018534933A5 (de) | ||
| RU2013125306A (ru) | Связывающие протеины, специфичные по отношению к инсулин-подобным факторам роста, и их использование | |
| JP2020522280A5 (de) | ||
| EA200101064A1 (ru) | Лечение раковых заболеваний путем комбинированного введения доцетаксела с рекомбинантными гуманизированными моноклональными анти-her2 антителами | |
| JP2020522281A5 (de) | ||
| HRP20221471T1 (hr) | Protutijela anti-fgfr3 i postupci za njihovu uporabu | |
| MXPA06003788A (es) | Anticuerpos completamente humanos contra 4-1bb humano (cd137). | |
| CY1115456T1 (el) | Μεθοδος χορηγησης αντισωματων αντι-ιl-5 | |
| RU2006132466A (ru) | Высококонцентрированные жидкие композиции анти-egfr антител | |
| CA2952113A1 (en) | Anti-axl antibodies | |
| JP2018529635A5 (de) | ||
| JP2020533965A5 (de) | ||
| AR046094A1 (es) | Anticuerpos completamente humanos contra 4-1bb humano | |
| WO2008100563A3 (en) | Compositions and methods for diagnosing and treating cancer |