HRP20110430T1 - Fsh glikozilacijski mutant - Google Patents

Fsh glikozilacijski mutant Download PDF

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Publication number
HRP20110430T1
HRP20110430T1 HR20110430T HRP20110430T HRP20110430T1 HR P20110430 T1 HRP20110430 T1 HR P20110430T1 HR 20110430 T HR20110430 T HR 20110430T HR P20110430 T HRP20110430 T HR P20110430T HR P20110430 T1 HRP20110430 T1 HR P20110430T1
Authority
HR
Croatia
Prior art keywords
fsh
seq
sequence
vector
cell
Prior art date
Application number
HR20110430T
Other languages
English (en)
Croatian (hr)
Inventor
M. Garone Louise
J. Arkinstall Stephen
H. Brondyk William
K. Campbell Robert
Jiang Xuliang
D. Mckenna Sean
Tepper Mark
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of HRP20110430T1 publication Critical patent/HRP20110430T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HR20110430T 2003-09-02 2004-09-02 Fsh glikozilacijski mutant HRP20110430T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49980203P 2003-09-02 2003-09-02
PCT/US2004/029042 WO2005020934A2 (en) 2003-09-02 2004-09-02 Fsh glycosylation mutant

Publications (1)

Publication Number Publication Date
HRP20110430T1 true HRP20110430T1 (hr) 2011-07-31

Family

ID=34272871

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20110430T HRP20110430T1 (hr) 2003-09-02 2004-09-02 Fsh glikozilacijski mutant

Country Status (23)

Country Link
US (1) US7700112B2 (de)
EP (1) EP1694271B1 (de)
JP (1) JP4653090B2 (de)
KR (1) KR101099809B1 (de)
CN (1) CN1984926B (de)
AT (1) ATE511829T1 (de)
AU (1) AU2004268683B2 (de)
BR (1) BRPI0413206A (de)
CA (1) CA2535522A1 (de)
CY (1) CY1112439T1 (de)
DK (1) DK1694271T3 (de)
EA (1) EA012175B1 (de)
ES (1) ES2367784T3 (de)
HR (1) HRP20110430T1 (de)
IL (1) IL174037A0 (de)
MX (1) MXPA06002119A (de)
NO (1) NO20061446L (de)
PL (1) PL1694271T3 (de)
PT (1) PT1694271E (de)
SI (1) SI1694271T1 (de)
UA (1) UA88879C2 (de)
WO (1) WO2005020934A2 (de)
ZA (1) ZA200601803B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1917276T3 (en) 2005-08-26 2018-05-07 Ares Trading Sa Process for Preparation of Glycosylated Interferon Beta
AU2006323925B2 (en) * 2005-12-09 2012-08-02 Ares Trading S.A. Method for purifying FSH or a FSH mutant
EP1976872B1 (de) 2005-12-22 2015-06-17 Merck Serono SA Fsh-mutanten
RS51792B (sr) * 2006-01-17 2011-12-31 Merck Serono Sa. Novi fsh sa glikozilacijom varijante d3n
EP2479570A3 (de) * 2007-03-26 2012-09-26 Novartis AG Prognostische Biomarker der renalen Sicherheit und Biomarker-Signatur zur Überwachung der Nierenfunktion
AR081755A1 (es) 2010-04-02 2012-10-17 Hanmi Holdings Co Ltd Formulacion de accion prolongada de la hormona estimuladora de los foliculos donde se usa un fragmento de inmunoglobulina, metodo de preparacion y metodo para tratar a un sujeto que sufre un trastorno reproductivo
CN108676096B (zh) * 2018-05-22 2022-03-29 北京伟杰信生物科技有限公司 重组猪fsh-ctp融合蛋白及其制备方法与应用
CA3160345A1 (en) * 2019-11-06 2021-05-14 The Regents Of The University Of Colorado, A Body Corporate Modified follicle-stimulating hormone and methods of using the same
CN114213523B (zh) * 2021-11-15 2024-07-09 广州源博医药科技有限公司 一种用于重组蛋白的高糖基化修饰序列及其重组猪促卵泡激素和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5156957A (en) 1983-11-02 1992-10-20 Genzyme Corporation Follicle stimulating hormone
US4923805A (en) 1983-11-02 1990-05-08 Integrated Genetics, Inc. Fsh
US4840896A (en) 1983-11-02 1989-06-20 Integrated Genetics, Inc. Heteropolymeric protein
US5639639A (en) 1983-11-02 1997-06-17 Genzyme Corporation Recombinant heterodimeric human fertility hormones, and methods, cells, vectors and DNA for the production thereof
US4845077A (en) 1984-04-03 1989-07-04 Serono Laboratories, Inc. Method of inducing ovulation
US4589402A (en) 1984-07-26 1986-05-20 Serono Laboratories, Inc. Method of in vitro fertilization
ATE148171T1 (de) 1989-02-21 1997-02-15 Univ Washington Modifizierte formen von fortpflanzungshormonen
US5338835A (en) 1989-02-21 1994-08-16 Washington University CTP-extended form of FSH
US5508261A (en) 1991-06-18 1996-04-16 University Of Medicine & Dentistry Of New Jersey Analogs of glycoprotein hormones having altered receptor binding specificity and activity and methods for preparing and using same
US6407205B1 (en) * 1997-06-04 2002-06-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College FSH-releasing peptides
ES2247710T3 (es) * 1997-06-20 2006-03-01 Akzo Nobel N.V. Antagonista de gonadotropina.
ATE279407T1 (de) * 1998-08-07 2004-10-15 Applied Research Systems Fsh mimetika zur behandlung von infertilität
TR200401810T4 (tr) * 2000-01-27 2004-09-21 Applied Research Systems Ars Holding N. V. Kısırlık tedavisinde fsh'ın kullanılması
AU2001231531A1 (en) * 2000-02-11 2001-08-20 Maxygen Aps Follicle stimulating hormones
US20020127652A1 (en) * 2000-02-11 2002-09-12 Schambye Hans Thalsgard Follicle stimulating hormones
AU2002368265B2 (en) 2001-10-22 2007-06-07 Merck Serono Sa Mutant glycoproteins

Also Published As

Publication number Publication date
KR101099809B1 (ko) 2011-12-27
EA200600526A1 (ru) 2007-04-27
CY1112439T1 (el) 2015-12-09
KR20070029620A (ko) 2007-03-14
IL174037A0 (en) 2006-08-01
MXPA06002119A (es) 2006-05-31
EP1694271B1 (de) 2011-06-08
SI1694271T1 (sl) 2011-08-31
CA2535522A1 (en) 2005-03-10
ATE511829T1 (de) 2011-06-15
JP2007508245A (ja) 2007-04-05
PT1694271E (pt) 2011-07-07
US20050100989A1 (en) 2005-05-12
DK1694271T3 (da) 2011-09-12
CN1984926A (zh) 2007-06-20
EP1694271A2 (de) 2006-08-30
US7700112B2 (en) 2010-04-20
ZA200601803B (en) 2007-05-30
BRPI0413206A (pt) 2006-10-03
WO2005020934A3 (en) 2007-02-15
AU2004268683A2 (en) 2005-03-10
ES2367784T3 (es) 2011-11-08
EA012175B1 (ru) 2009-08-28
JP4653090B2 (ja) 2011-03-16
PL1694271T3 (pl) 2011-11-30
CN1984926B (zh) 2012-04-11
WO2005020934A2 (en) 2005-03-10
NO20061446L (no) 2006-03-30
UA88879C2 (en) 2009-12-10
AU2004268683A1 (en) 2005-03-10
AU2004268683B2 (en) 2010-06-24
HK1101315A1 (en) 2007-10-12

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