HRP20200399T1 - Postupak i stroj za proizvodnju vrećica za sterilne otopine - Google Patents

Postupak i stroj za proizvodnju vrećica za sterilne otopine Download PDF

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HRP20200399T1
HRP20200399T1 HRP20200399TT HRP20200399T HRP20200399T1 HR P20200399 T1 HRP20200399 T1 HR P20200399T1 HR P20200399T T HRP20200399T T HR P20200399TT HR P20200399 T HRP20200399 T HR P20200399T HR P20200399 T1 HRP20200399 T1 HR P20200399T1
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filter
handle
bag
product bag
liquid
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Grant Anthony BOMGAARS
Joseph Vincent Ranalletta
Yuanpang Samuel Ding
Ying-Cheng Lo
Mark Edward Pasmore
Michael Joseph Sadowski
Anastasios HRISTAKOS
Thomas Edward DUDAR
Bernd Krause
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Baxter International Inc.
Baxter Healthcare Sa
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Publication of HRP20200399T1 publication Critical patent/HRP20200399T1/hr

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B65B3/006—Related operations, e.g. scoring ampoules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/10—Testing of membranes or membrane apparatus; Detecting or repairing leaks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/26—Methods or devices for controlling the quantity of the material fed or filled
    • B65B3/28—Methods or devices for controlling the quantity of the material fed or filled by weighing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/02—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/02—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
    • B65B31/021—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas the containers or wrappers being interconnected
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/02—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
    • B65B31/024—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas specially adapted for wrappers or bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B43/00—Forming, feeding, opening or setting-up containers or receptacles in association with packaging
    • B65B43/42—Feeding or positioning bags, boxes, or cartons in the distended, opened, or set-up state; Feeding preformed rigid containers, e.g. tins, capsules, glass tubes, glasses, to the packaging position; Locating containers or receptacles at the filling position; Supporting containers or receptacles during the filling operation
    • B65B43/54—Means for supporting containers or receptacles during the filling operation
    • B65B43/60—Means for supporting containers or receptacles during the filling operation rotatable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B51/00—Devices for, or methods of, sealing or securing package folds or closures; Devices for gathering or twisting wrappers, or necks of bags
    • B65B51/10—Applying or generating heat or pressure or combinations thereof
    • B65B51/26—Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
    • B65B51/30—Devices, e.g. jaws, for applying pressure and heat, e.g. for subdividing filled tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B57/00—Automatic control, checking, warning, or safety devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B39/00—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers
    • B65B2039/008—Strainer means

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Package Closures (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Packages (AREA)

Claims (22)

1. Postupak dobivanja većeg broja napunjenih vrećica proizvoda (28, 100) sterilne tekućine, naznačen time, da taj postupak uključuje: upotrebu većeg broja vrećica proizvoda, pri čemu svaka vrećica proizvoda (100) ima mjehur (102), držak (104, 155) fluidno spojen na otvor (114) mjehura (102) i filtar (106, 156 ) postavljen u liniji s drškom (104, 156); i izrada većeg broja napunjenih vrećica proizvoda (28, 100) izvođenjem sljedećeg postupka na svakoj vrećici proizvoda (100): barem djelomično napuniti vrećicu proizvoda (100) tekućinom za dobivanje napunjene vrećice proizvoda (28, 100), pri čemu punjenje vrećice proizvoda (100) uključuje prolazak tekućine kroz filtar (106, 156) i u mjehur (102); nakon punjenja, zabrtviti napunjenu vrećicu proizvoda (28, 100); obavljanje ispitivanja integriteta na filtru (106, 156) radi utvrđivanja prisutnosti bilo kakvih strukturalnih nedostataka u filtru (106, 156) koji mogu spriječiti filtar (106, 156) da adekvatno sterilizira tekućinu dok ona prolazi kroz držak (104, 156) i u mjehur (102); i povezivanje integriteta sadržaja napunjene vrećice proizvoda (28, 100) s integritetom filtra (106, 156) na temelju rezultata ispitivanja integriteta.
2. Postupak u skladu s patentnim zahtjevom 1, naznačen time, da nadalje uključuje povezivanje ulaznog otvora (124) drška (104, 156) i izlaza (532) mlaznice (508).
3. Postupak u skladu s patentnim zahtjevom 1 ili 2, naznačen time, da nadalje uključuje pričvršćivanje vrećice proizvoda (100) na jedno od većeg broja pomičnih postolja (200, 310) i rotiranje karusela (72, 300) oko središnje osi (X), karusel (72, 300) nosi veći broj pomičnih postolja (200, 310), ravnomjerno raspoređenih po obodu karusela (72, 300), pri čemu se rotiranjem karusela (72, 300) pomiče svaki od većeg broja postolja (200, 310) između dva od većeg broja položaja, pri čemu povezivanje ulaznog otvora (124) drška (104, 156) s mlaznicom (508) po izboru uključuje pomicanje ležišta (200, 310).
4. Postupak u skladu s bilo kojim patentnim zahtjevom od 2 do 3, naznačen time, da barem djelomično punjenje vrećice proizvoda (100) uključuje izvlačenje tekućine iz vreće za miješanje kroz cijev za punjenje (60) i doziranje tekućine iz cijevi za punjenje (60 ) kroz izlaz (532) mlaznice (508), pri čemu povezivanje ulaznog otvora (124) drške (104, 156) i mlaznice (508) po izboru uključujući primjenu Luerovog spoja mlaznice (508) na ulazni otvor (124) drška (104, 156).
5. Postupak u skladu s bilo kojim od patentnih zahtjeva od 2 do 4, naznačen time, da nadalje uključuje uklanjanje sterilnog poklopca (108, 108b, 108c, 154, 180, 180a) koji prekriva ulazni otvor (124) drške (104, 156) prije povezivanja ulaznog otvora u mlaznicu (508).
6. Postupak u skladu s bilo kojim od patentnih zahtjeva od 1 do 5, naznačen time, da uključuje mjerenje količine tekućine u mjehuru (102) napunjene vrećice proizvoda (28, 100) s pomoću tlačne ćelije (528) i prekid punjenja vrećice proizvoda (100) kada vrećica proizvoda (100) sadržava unaprijed određenu količinu tekućine, pri čemu obustava punjenja po izboru uključuje uklanjanje ulaznog otvora (124) drška (104, 156) iz mlaznice (508).
7. Postupak u skladu s patentnim zahtjevom 6, naznačen time, da uključuje odvajanje ulaznog otvora (124) drška (104, 156) iz mlaznice (508) kada se vrećica s proizvodom (100) napuni na unaprijed određenu količinu.
8. Postupak u skladu s bilo kojim od patentnih zahtjeva od 1 do 7, naznačen time, da provođenje testa integriteta uključuje provođenje barem jednog ispitivanja mjehurića i testa smanjenja tlaka.
9. Postupak u skladu s bilo kojim od patentnih zahtjeva 1 do 8, naznačen time, da provođenje ispitivanja integriteta uključuje detekciju pritiska na filtar (106, 156) s pomoću tlačnog senzora.
10. Postupak u skladu s bilo kojim od zahtjeva od 1 do 9, naznačen time, da uključuje odlaganje napunjene vrećice proizvoda (28, 100) u prvu posudu za odbačene vrećice ako filtar (106, 156) ne prođe ispitivanje integriteta i drugi spremnik za prihvaćene vrećice ako filtar (106, 156) prođe ispitivanje integriteta, a po želji nadalje uključuje pomicanje skretnice (708) usmjerene prema jednoj od prve posude ili druge posude na temelju rezultata ispitivanja integriteta filtra (106, 156).
11. Postupak u skladu s bilo kojim od patentnih zahtjeva 1 do 10, naznačen time, da prolazak tekućine kroz filtar (106, 156) uključuje prolazak tekućine kroz filtar za sterilizaciju.
12. Postupak u skladu s bilo kojim od patentnih zahtjeva od 1 do 11, naznačen time, da propuštanje tekućine kroz filtar (106, 156) uključuje prolazak tekućine kroz filtar od 0,2 mikrona i po želji nadalje uključuje uklanjanje napunjene vrećice proizvoda (28, 100) s postolja (200, 310).
13. Automatizirani stroj za izradu sterilnih vrećica proizvoda napunjenih tekućinom (28, 100), naznačen time, da sadržava: sklop mlaznica (506); nosač s pomičnom postoljem (200, 310) za prihvat barem jedne vrećice proizvoda (100), vrećica proizvoda (100) uključuje mjehur (102), držak (104, 156), fluidno spojen na otvor (114) mjehura (102) i filtar (106, 156) koji smješten u liniji s drškom (104, 156); stanicu za punjenje (36, 360), koja uključuje sklop mlaznica (506), sklop mlaznica (506) s mlaznicom (508) izrađen da zahvaća ulazni otvor (124) drška (104, 156) i fluidno se poveže s mjehurom (102); stanicu za brtvljenje i rezanje (38), koja uključuje uređaj za brtvljenje (602) konfiguriran za brtvljenje drška (104, 156) vrećice proizvoda (100) na mjestu iznad ulaznog otvora (114) mjehura (102) i ispod filtara (106, 156) te uređaj za rezanje (602, 604) s oštricom (624) za rezanje drška (104, 156) na mjestu iznad brtve i ispod filtra (106, 156); te ispitnu stanicu (36, 40) koja uključuje uređaj za ispitivanje integriteta filtra, a uređaj za ispitivanje integriteta filtra uključuje uređaj za ispitivanje filtra (704) i tlačni senzor; pri čemu je uređaj za ispitivanje filtra (704) konfiguriran tako da se priključi na ulazni otvor (124) drška (104, 156) svake sterilne vrećice proizvoda (28, 100) napunjene tekućinom kako bi se izvršio test integriteta filtra i utvrdila prisutnost bilo kakvog strukturnog nedostatka u filtru (106, 156) koje mogu spriječiti da filtar (106, 156) adekvatno sterilizira neku tekućinu dok tekućina prolazi kroz držak (104, 156) i u mjehur (102), i pri čemu se uspješno ispitivanje integriteta filtara (106, 156) korelira s prihvaćanjem vrećice, a neuspješno ispitivanje integriteta filtara (106, 156) korelira s odbačenom vrećicom.
14. Stroj u skladu s patentnim zahtjevom 13, naznačen time, da ispitna stanica (36, 40) nadalje uključuje skretnicu (708) konfiguriranu za pomicanje između prvog i drugog položaja i pri čemu skretnica (708) zauzima prvi položaj kao odgovor na rezultat prolaska ispitivanja integriteta filtra i skretnica (708) zauzima drugi položaj kao odgovor na neuspješan rezultat ispitivanja integriteta filtara, pri čemu je po izboru skretnica (708) smještena ispod napunjene vrećice proizvoda (28, 100) i konfigurirana za usmjeravanje napunjene vrećice proizvoda (28, 100) u prvu ili drugu posudu, pri čemu, po izboru, prva posuda prima odbačenu napunjenu vrećicu proizvoda (28, 100) iz skretnice (708) u prvom položaju, a drugi spremnik prima prihvaćenu napunjenu vrećicu proizvoda (28, 100) iz skretnice (708) u drugom položaju, a nadalje po želji uključuje stanicu s rampom (425) koja se nalazi između ispitne stanice (36, 40) i stanice za punjenje, pri čemu je rampa (425) konfigurirana za zahvaćanje sterilnog zatvarača (108, 108b, 108c, 154, 180, 180a) vrećice s proizvodom (100) i uklanjanja sterilnog zatvarača (108, 108b, 108c, 154, 180, 180a), dok se vrećica proizvoda (100) i rampa (425) kreću jedna u odnosu na drugu, pri čemu rampa (425) po izboru ima oblik vilice i uključuje utor (416) za uklanjanje sterilnog zatvarača (108, 108b, 108c, 154, 180, 180a ).
15. Stroj u skladu s bilo kojim patentnim zahtjevom od 13 do 14, naznačen time, da nosač sadržava karusel (72, 300) koji se može okretati oko središnje osi (X), pri čemu karusel (72, 300) nosi veći broj pomičnih ležišta (200, 310) ) i pri čemu je više postaja po izboru raspoređeno oko oboda karusela (72, 300).
16. Stroj u skladu s bilo kojim patentnim zahtjevom od 13 do 15, naznačen time, da nosač nosi tlačnu ćeliju (528) za praćenje vrećice proizvoda (100).
17. Stroj u skladu s bilo kojim patentnim zahtjevom od 13 do 16, naznačen time, da se postolje (200, 310) može pomicati u odnosu na svaku od više postaja.
18. Stroj u skladu s bilo kojim patentnim zahtjevom od 13 do 17, naznačen time, da uređaj za brtvljenje (602) uključuje pokretač (614, 616) za pomicanje brtvila prema i od drška (104, 156), pri čemu uređaj za rezanje (602 604) po želji uključuje pokretač (622) za pomicanje noža (624) uređaja za rezanje (602, 604) prema i od drška (104, 156).
19. Stroj u skladu s bilo kojim patentnim zahtjevom od 13 do 18, naznačen time, da nadalje uključuje vrećicu za miješanje koja sadržava tekućinu, a vrećica za miješanje je fluidno spojena na sklop mlaznica (506).
20. Stroj u skladu s patentnim zahtjevom 19, naznačen time, da nadalje uključuje barem jedan sterilizacijski filtar smješten u cijevi za punjenje (60), pri čemu cijev za punjenje (60) fluidno povezuje vrećicu za miješanje sa sklopom mlaznica (506).
21. Postupak u skladu s bilo kojim od patentnih zahtjeva od 1 do 12, naznačen time, da izrada većeg broja vrećica proizvoda (100) uključuje izradu barem jedne od većeg broja vrećica proizvoda (100) koja uključuje više mjehura (102) spojenih na držak (104, 156).
22. Stroj u skladu s bilo kojim patentnim zahtjevom od 13 do 20, naznačen time, da vrećica proizvoda (100) uključuje više mjehura (102) spojenih na držak (104, 156).
HRP20200399TT 2016-01-22 2017-01-20 Postupak i stroj za proizvodnju vrećica za sterilne otopine HRP20200399T1 (hr)

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US201662281825P 2016-01-22 2016-01-22
PCT/US2017/014264 WO2017127632A1 (en) 2016-01-22 2017-01-20 Method and machine for producing sterile solution product bags
EP17705206.5A EP3405400B1 (en) 2016-01-22 2017-01-20 Method and machine for producing sterile solution product bags

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US (2) US11021275B2 (hr)
EP (2) EP3636555B1 (hr)
JP (2) JP6526917B2 (hr)
KR (2) KR101981022B1 (hr)
CN (2) CN108473218B (hr)
AU (2) AU2017209214B2 (hr)
BR (1) BR112018013913B1 (hr)
CA (2) CA3097210C (hr)
CO (1) CO2018006820A2 (hr)
DE (1) DE112017000474T5 (hr)
DK (1) DK3405400T3 (hr)
ES (2) ES2953037T3 (hr)
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HR (1) HRP20200399T1 (hr)
HU (1) HUE049878T2 (hr)
IL (1) IL260108B (hr)
MX (1) MX385034B (hr)
MY (1) MY193040A (hr)
NZ (1) NZ743477A (hr)
PH (2) PH12022551159A1 (hr)
PL (1) PL3405400T3 (hr)
PT (1) PT3405400T (hr)
RU (2) RU2019108810A (hr)
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Publication number Priority date Publication date Assignee Title
DE102018103889A1 (de) 2018-02-21 2019-08-22 Fresenius Medical Care Deutschland Gmbh Zusammenschluss von Lösungsbeuteln für die Dialyse und Verfahren zu deren Befüllung
DE102018103863A1 (de) 2018-02-21 2019-08-22 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zum Befüllen von Lösungsbeuteln für die Dialyse
DE102018103950A1 (de) 2018-02-21 2019-08-22 Fresenius Medical Care Deutschland Gmbh Magazin mit Lösungsbeuteln für die Dialyse und Verfahren zu deren Befüllung
CN109335386B (zh) * 2018-09-07 2021-03-12 湖南金牛环保设备有限公司 一种环保型垃圾桶
US11565844B2 (en) 2018-12-21 2023-01-31 S.C. Johnson & Son, Inc. Methods and apparatus to facilitate plastic film processing
CN120207654A (zh) 2019-11-25 2025-06-27 德卡产品有限公司 生产和封装流体的系统、密封构件分配器、贮存器进给设备、袋密封设备、贮存器填充套件、填充贮存器或袋的方法、填充和采样喷嘴
EP4126512A2 (en) 2020-04-03 2023-02-08 Baxter International Inc. Method and system for producing sterile solution product bags
IT202000025108A1 (it) * 2020-10-22 2022-04-22 Baxter Int Sistema di generazione di fluidi medicali
CA3198797A1 (en) * 2020-11-25 2022-06-02 Deka Products Limited Partnership Systems, methods, and apparatuses for producing and packaging fluids
CA3201044A1 (en) 2020-12-28 2022-07-07 Gianni Di Stefani Method and system for producing sterile solution filled containers
JP7300116B2 (ja) 2021-10-14 2023-06-29 大日本印刷株式会社 内容物充填システム及び殺菌方法
JP7245453B1 (ja) 2021-10-14 2023-03-24 大日本印刷株式会社 内容物充填システム及び殺菌方法
CN119173446A (zh) 2022-03-08 2024-12-20 赤盾医疗有限公司 机器人药物制备系统中的流体转移站
DE102023124844A1 (de) * 2023-09-14 2025-03-20 Groninger & Co. Gmbh Verfahren zur Vorbereitung eines Abfüllvorgangs
CN117382990A (zh) * 2023-10-20 2024-01-12 郑州启明轩智能装备有限公司 一种刀削面包装机
KR102660396B1 (ko) * 2024-01-03 2024-04-24 에이피이(주) 이동형 무균 필터 테스트 시스템
US20250327011A1 (en) * 2024-04-22 2025-10-23 Hyperius Biotech Inc. Handling kit for a flexible bag and related systems and methods
KR102783874B1 (ko) * 2024-07-17 2025-03-21 에이피이(주) 무균 필터 테스트 시스템
ES3058775A1 (es) * 2024-09-11 2026-03-12 Servicios Gestion & Automatizacion Del Levante Srl Plataforma giratoria y método de control de calidad de bolsas de alimentos mediante presión

Family Cites Families (248)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1714253A (en) 1922-11-16 1929-05-21 Aluminum Co Of America Joint for wires or cables
US3161310A (en) 1960-10-14 1964-12-15 Baxter Don Inc Parenteral solution container
US3938519A (en) 1974-02-26 1976-02-17 American Hospital Supply Corporation Medical liquid container with a toggle film leak tester and method of leak testing with same
US3902068A (en) 1974-04-10 1975-08-26 Modern Controls Inc Method and apparatus for measuring the gas transmission through packaging materials
US4036698A (en) 1974-11-06 1977-07-19 Millipore Corporation Method and apparatus for membrane filter sterility testing
SE414385B (sv) 1977-03-09 1980-07-28 Ake Andersson Fyllningsmaskin for flytande produkter
US4116646A (en) 1977-05-20 1978-09-26 Millipore Corporation Filter unit
US4265760A (en) 1979-02-26 1981-05-05 Becton Dickinson & Company Device for dilution and delivery of in vivo chemicals
US4360435A (en) * 1979-11-01 1982-11-23 Baxter Travenol Laboratories, Inc. Process for sterilizing and transferring a solution
US4353398A (en) 1981-01-05 1982-10-12 Automatic Liquid Packaging, Inc. Sterilizing apparatus for an encapsulating machine
US4502614A (en) 1981-01-05 1985-03-05 Automatic Liquid Packaging, Inc. Sterilizing apparatus for an encapsulating machine
US4623516A (en) 1981-01-05 1986-11-18 Automatic Liquid Packaging, Inc. Sterilizing method for an encapsulating machine
JPS5840202U (ja) 1981-09-07 1983-03-16 三菱レイヨン株式会社 精密「ろ」
US4671762A (en) 1982-04-01 1987-06-09 Automatic Liquid Packaging, Inc. Apparatus for filling a molded container with liquid contents
US4521366A (en) 1982-06-24 1985-06-04 Baxter Travenol Laboratories, Inc. Method for closing and sealing plastic tubing using a hot die and a rotating cold die
DE3238649C2 (de) * 1982-10-19 1987-03-19 Hagen Dr. 8500 Nürnberg Theuer Mehrkompartimentbeutel
US4515007A (en) 1983-01-04 1985-05-07 The United States Of America As Represented By The United States Department Of Energy Method of and apparatus for testing the integrity of filters
EP0116362A3 (en) 1983-02-11 1985-05-15 Millipore Corporation Sterile package for therapeutic composition
CA1221645A (en) 1983-02-28 1987-05-12 Yoshihiro Okano Filtration apparatus using hollow fiber-membrane
JPS6058530A (ja) 1983-09-09 1985-04-04 Fujisawa Pharmaceut Co Ltd メンブランフイルタの試験方法および装置
DE3477691D1 (en) 1983-09-09 1989-05-18 Fujisawa Pharmaceutical Co Apparatus for testing membrane filters, and apparatus for sterilizing liquids with use of membrane filter
JPS60197287A (ja) 1984-03-19 1985-10-05 Fujisawa Pharmaceut Co Ltd 液体の無菌濾過装置
DE3333283A1 (de) 1983-09-15 1985-04-18 Gerhard 3429 Krebeck Lorenz Aufbereitungssystem fuer infusionsloesungen
EP0138060B1 (en) 1983-09-16 1990-03-07 Mitsubishi Rayon Co., Ltd. Hollow-fiber filtering module and water purification device utilizing it
US4507114A (en) 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
JPS6091203U (ja) 1983-11-28 1985-06-22 旭化成株式会社 注射器型ミニ分離器
GB2153247A (en) 1984-01-31 1985-08-21 Baxter Travenol Lab Filter
US4636313A (en) 1984-02-03 1987-01-13 Vaillancourt Vincent L Flexible filter disposed within flexible conductor
US4610790A (en) * 1984-02-10 1986-09-09 Sterimatics Company Limited Partnership Process and system for producing sterile water and sterile aqueous solutions
JPS60232085A (ja) 1984-04-28 1985-11-18 Kanegafuchi Chem Ind Co Ltd 無菌的濾過方法
US4807676A (en) 1985-02-26 1989-02-28 Baxter International Inc. Fluid transfer workstation
US4668401A (en) 1985-06-19 1987-05-26 Mitsubishi Rayon Co., Ltd. Hollow-fiber filter module and filtration method using the same
JPS621410A (ja) 1985-06-26 1987-01-07 Kitazawa Valve:Kk 精密濾過装置
US4695382A (en) 1985-11-18 1987-09-22 Microgon, Inc. Combined fluid filter and delivery tubing
US4779448A (en) 1986-01-28 1988-10-25 Donaldson Company, Inc. Photoelectric bubble detector apparatus and method
US4730435A (en) 1986-04-07 1988-03-15 Aqua-Chem, Inc. Sterile docking system for filling IV bags
US4937194A (en) * 1986-05-12 1990-06-26 Baxter International Inc. Method for metering nutrient media to cell culture containers
US4712590A (en) 1986-05-30 1987-12-15 Baxter Travenol Laboratories, Inc. Electrical connection means for multiple bulk compounding systems
USRE33924E (en) 1986-07-16 1992-05-12 Autologous Blood Corp. Apparatus and method for storing and processing blood
US4915847A (en) * 1987-08-04 1990-04-10 Baxter International Inc. Cryoglobulin separation
SE8605004D0 (sv) 1986-11-24 1986-11-24 Alfa Laval Food Eng Ab Arrangemang vid membranfilter
US4820297A (en) * 1986-12-12 1989-04-11 Baxter International Inc. Fluid delivery system with integrally formed sample cell
US4842028A (en) 1987-05-13 1989-06-27 Baxter International Inc. Fluid transfer apparatus
ES2032420T3 (es) 1987-11-02 1993-02-16 Pall Corporation Aparato y procedimiento para el control del flujo de fluidos.
JPH01139108A (ja) 1987-11-25 1989-05-31 Fuji Photo Film Co Ltd 濾過システム
US4881176B1 (en) 1988-01-22 1997-06-17 Thokon Corp Filter analyzing system
JPH02290228A (ja) 1988-12-22 1990-11-30 Asahi Chem Ind Co Ltd 再生セルロース中空糸膜微量濾過用モジュール
US4964261A (en) 1989-01-24 1990-10-23 Benn James A Bag filling method and apparatus for preparing pharmaceutical sterile solutions
JPH038420A (ja) 1989-06-05 1991-01-16 Fuji Photo Film Co Ltd 完全性試験方法
US4943287A (en) 1989-07-17 1990-07-24 Miles Inc. Red blood cell storage system
JPH03110445A (ja) 1989-09-25 1991-05-10 Fuji Photo Film Co Ltd 完全性試験方法
JPH04142445A (ja) 1990-10-02 1992-05-15 Fuji Photo Film Co Ltd 完全性試験方法
US5221474A (en) 1990-12-28 1993-06-22 Terumo Kabushiki Kaisha Transfusion filtering device
JP2706853B2 (ja) 1991-01-16 1998-01-28 ハウス食品株式会社 メンブランフィルタの完全性検査方法及び検査装置
US5490848A (en) 1991-01-29 1996-02-13 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration System for creating on site, remote from a sterile environment, parenteral solutions
US5180504A (en) 1991-05-22 1993-01-19 Baxter International Inc. Systems and methods for removing undesired matter from blood cells
DE4119040C2 (de) 1991-06-10 1997-01-02 Pall Corp Verfahren und Gerät zum Testen des Betriebszustands von Filterelementen
US5368586A (en) 1991-06-21 1994-11-29 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Closure for a drug-vial
US5209044A (en) * 1991-07-11 1993-05-11 Innovative Automation Inc. Automatic tube filling device and process
JPH0523551A (ja) 1991-07-18 1993-02-02 Fuji Photo Film Co Ltd 完全性試験装置
US5310094A (en) 1991-11-15 1994-05-10 Jsp Partners, L.P. Preservative free sterile fluid dispensing system
ES1019546Y (es) 1991-12-05 1992-11-01 Grifols Lucas Victor Bolsa para liquidos de perfusion, perfeccionada.
US5275724A (en) 1991-12-10 1994-01-04 Millipore Corporation Connector apparatus and system
US6149997A (en) 1992-01-30 2000-11-21 Baxter International Inc. Multilayer coextruded material for medical grade products and products made therefrom
DE4209519C3 (de) 1992-03-24 2000-06-15 Pall Corp Verfahren und Gerät zum schnellen Testen der Unversehrtheit von Filterelementen
EP0592066B1 (en) 1992-05-01 1997-09-03 Memtec Japan Limited Apparatus for testing membrane filter integrity
JP2945988B2 (ja) 1992-05-01 1999-09-06 ユー・エス・フィルター・ジャパン株式会社 メンブレンフィルタ完全性試験装置
US5788862A (en) 1992-05-13 1998-08-04 Pall Corporation Filtration medium
US5480554A (en) 1992-05-13 1996-01-02 Pall Corporation Integrity-testable wet-dry-reversible ultrafiltration membranes and method for testing same
US5249409A (en) * 1992-06-02 1993-10-05 Mhb Industries Corp. Method and apparatus for manufacture of wicketed bags with an encapsulated article and the bags formed thereby
US5282380A (en) 1992-06-30 1994-02-01 Millipore Corporation Integrity test for membranes
JPH0634636A (ja) 1992-07-17 1994-02-10 Tosoh Corp ステロイドホルモンの測定法
EP0667954A4 (en) 1992-11-06 1995-12-27 Pall Corp DEVICE AND METHOD FOR TESTING THE INTEGRITY OF POROUS ELEMENTS.
ES1024044Y (es) 1993-03-16 1994-04-01 Grifols Lucas Maquina para el llenado esteril y su comprobacion, de bolsas esteriles para liquidos de perfusion.
US5334180A (en) 1993-04-01 1994-08-02 Abbott Laboratories Sterile formed, filled and sealed flexible container
FR2704432B1 (fr) 1993-04-27 1995-06-23 Hospal Ind Dispositif d'injection de liquide dans un circuit extracorporel de sang.
WO1995006515A1 (en) 1993-08-30 1995-03-09 Pfizer Inc. Apparatus and method for testing hydrophobic filters
JPH0768136A (ja) 1993-09-02 1995-03-14 Tsuchiya Mfg Co Ltd 中空糸膜型分離モジュ−ル及びその製造方法
DE4339589C1 (de) 1993-11-20 1994-12-08 Sartorius Gmbh Verfahren und Einrichtung zum Prüfen von Filterelementen durch einen Wasserintrusionstest
FR2718033B1 (fr) * 1994-03-31 1998-02-13 Inoteb Dispositif de filtration de fluides biologiques et son application.
DE4413081C1 (de) 1994-04-15 1995-03-09 Sartorius Gmbh Verfahren und Vorrichtung zur Integritätsprüfung von Filterelementen in Räumen mit besonderen Sicherheitsanforderungen
US5538638A (en) 1994-06-27 1996-07-23 Hedman; Hilary R. Method of testing IV admixtures for contaminants
US7332125B2 (en) 1994-10-13 2008-02-19 Haemonetics Corporation System and method for processing blood
US5507959A (en) 1994-11-04 1996-04-16 Advanced Micro Devices, Inc. Apparatus for wetting, flushing and performing integrity checks on encapsulated PTFE filters
AU1735895A (en) 1994-11-14 1996-06-06 W.L. Gore & Associates, Inc. Hydrophilized filter cartridge and process for making same
US5591344A (en) 1995-02-13 1997-01-07 Aksys, Ltd. Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof
US5488811A (en) 1995-02-21 1996-02-06 Abbott Laboratories On-line air filter integrity testing apparatus
DE19534417A1 (de) 1995-09-16 1997-03-20 Fresenius Ag Verfahren zum Überprüfen von mindestens einem im Dialysierflüssigkeitssystem einer Vorrichtung zur extrakorporalen Blutbehandlung angeordneten Filter
US5904846A (en) 1996-01-16 1999-05-18 Corning Costar Corporation Filter cartridge having track etched membranes and methods of making same
DE19605357A1 (de) 1996-02-14 1997-08-21 Braun Melsungen Ag Flexibler Kunststoffbehälter
US5881535A (en) 1996-04-09 1999-03-16 Baxter International, Inc. Apparatus and method for filling and sealing intravenous solution bags
FR2749190B1 (fr) 1996-05-28 1998-09-18 Omnium Traitement Valorisa Procede et installation pour tester in situ l'integrite des membranes de filtration
DE29618092U1 (de) 1996-10-18 1996-12-12 Sartorius AG, 37075 Göttingen Auf Integrität testbare Filterkassette aus hydrophilen, porösen Polymembranen mit verbesserter Filtrationssicherheit und Filtrationsleistung
JPH10225628A (ja) 1997-02-14 1998-08-25 Nippon Millipore Kk 交差濾過装置
GB2365511B (en) 1997-07-16 2002-03-27 Pall Corp Valves for filters
US6059968A (en) * 1998-01-20 2000-05-09 Baxter International Inc. Systems for processing and storing placenta/umbilical cord blood
US6123859A (en) 1998-04-22 2000-09-26 Hemasure Inc. Method for in-line filtering biological liquid
IT1299672B1 (it) 1998-05-20 2000-03-24 Enologica Vason Srl Apparecchiatura per eseguire test di filtrabilita' di liquidi e di integrita' di mezzi filtranti, in particolare nel settore enologico
US6358420B2 (en) 1998-06-01 2002-03-19 Baxter International Inc. Blood collection method employing an air venting blood sample tube
US20040031744A1 (en) 1998-12-09 2004-02-19 Jms Co., Ltd. Infusion filter
DE19926002A1 (de) 1999-06-08 2000-12-14 Sartorius Gmbh Verfahren zur Integritätsprüfung von Filtereinheiten und Prüfeinrichtung zur Durchführung des Verfahrens
US6324898B1 (en) 1999-12-21 2001-12-04 Zenon Environmental Inc. Method and apparatus for testing the integrity of filtering membranes
US6245228B1 (en) 2000-02-28 2001-06-12 Maher I. Kelada Emergency water treatment device
US6660171B2 (en) 2000-03-27 2003-12-09 Peter Zuk, Jr. High capacity gravity feed filter for filtering blood and blood products
US6599484B1 (en) 2000-05-12 2003-07-29 Cti, Inc. Apparatus for processing radionuclides
GB2362841A (en) 2000-06-03 2001-12-05 Secr Defence Method and apparatus for testing filters
JP3518596B2 (ja) 2000-10-02 2004-04-12 株式会社スキャンテクノロジー ソフトバッグ総合検査システム
CN2449714Y (zh) * 2000-11-09 2001-09-26 黄斌 一次性使用去白细胞输血器
EP1399193B1 (en) * 2001-02-16 2014-01-08 Piedmont Renal Clinics, P.A. Automated peritoneal dialysis system and process with in-line sterilization of dialysate
DE60217201T2 (de) 2001-02-28 2007-11-08 Grifols, S.A. Vorrichtung zum Füllen von Behältern für pharmazeutische Zwecke und dergleichen
DE10116335C1 (de) 2001-04-02 2002-10-17 Sartorius Gmbh Verfahren zur Durchführung eines Integritätstest von Filterelementen
US6451201B1 (en) 2001-04-25 2002-09-17 Zenon Environmental Inc. Distributed on-line integrity testing for immersed membranes
FR2828116B1 (fr) 2001-08-06 2003-11-14 Ondeo Degremont Procede et dispositif de controle de l'integrite des modules de filtration membranaire
CN2498602Y (zh) 2001-09-07 2002-07-03 国家海洋局杭州水处理技术研究开发中心 一种膜滤芯完整性测试仪
DE10165044B4 (de) 2001-10-17 2013-01-24 Sartorius Stedim Biotech Gmbh Vorrichtung zur Durchführung von Integritätstests von Filterelementen
DE10151269B4 (de) 2001-10-17 2005-08-25 Sartorius Ag Verfahren zum Überwachen der Integrität von Filtrationsanlagen
DE10151270B4 (de) 2001-10-17 2006-10-26 Sartorius Ag System und Verfahren zur Überwachung der Integrität eines Filterelementes
DE10151271B4 (de) 2001-10-17 2010-01-07 Sartorius Stedim Biotech Gmbh Verfahren zur Durchführung von Integritätstests von Filterlementen
US7727219B2 (en) * 2001-10-22 2010-06-01 Vita 34 Ag Sterile system and methods for collecting, transporting, storing and cyropreserving body fluids
US7011758B2 (en) 2002-02-11 2006-03-14 The Board Of Trustees Of The University Of Illinois Methods and systems for membrane testing
FR2835752B1 (fr) 2002-02-13 2004-11-26 Maco Pharma Sa Unite de filtration comprenant des couches deleucocytantes calandrees
US6947126B2 (en) * 2002-03-13 2005-09-20 The Boc Group, Inc. Dilution apparatus and method of diluting a liquid sample
US7279107B2 (en) 2002-04-16 2007-10-09 Gambro, Inc. Blood component processing system, apparatus, and method
US20050209547A1 (en) 2002-06-06 2005-09-22 Burbank Jeffrey H Last-chance quality check and/or air/pathogen filter for infusion systems
AUPS282902A0 (en) 2002-06-07 2002-06-27 Pak Technologies Group Pty Ltd Flexible pouch, filling and heat sealing line for flexible pouches, and containers for supporting and moving the flexible pouches
US9283521B2 (en) 2002-06-14 2016-03-15 Parker-Hannifin Corporation Single-use manifold and sensors for automated, aseptic transfer of solutions in bioprocessing applications
US6712963B2 (en) * 2002-06-14 2004-03-30 Scilog, Llc Single-use manifold for automated, aseptic transfer of solutions in bioprocessing applications
DE10227160B4 (de) 2002-06-18 2007-09-27 Sartorius Biotech Gmbh Verfahren zur Durchführung eines Integritätstests von Filterelementen
FR2842122B1 (fr) 2002-07-10 2004-08-13 Maco Pharma Sa Unite de deleucocytation selective d'un produit plaquettaire
US20040134851A1 (en) 2002-07-24 2004-07-15 Lucas Jeffrey A. Polymeric surface treatment of filter media
EP1491623A4 (en) * 2002-08-19 2006-02-01 Olympus Corp INCUBATOR AND DEVICE FOR CULTURE
DE20212749U1 (de) * 2002-08-20 2002-10-10 Wang, Chih-Hung, Taipeh/T'ai-pei Abfüllanlage zum Abfüllen von Infusionsbeuteln
WO2004052270A1 (ja) 2002-12-12 2004-06-24 Asahi Kasei Kabushiki Kaisha ウイルス除去バッグ及びそれを用いたウイルス除去方法
ATE434454T1 (de) * 2003-01-07 2009-07-15 Nxstage Medical Inc Chargenfiltriersystem zur herstellung einer sterilen ersatzflüssigkeit für nierenbehandlungen
ITMI20030897A1 (it) 2003-04-30 2004-11-01 Crb Nederland B V Procedimento e apparecchiatura per frazionare sangue.
US6984331B2 (en) 2003-05-14 2006-01-10 Steris Inc. Filter cleaning and decontaminating system
DE10340522B4 (de) 2003-09-03 2015-04-09 Sartorius Stedim Biotech Gmbh Vorrichtung zur Sterilitätsprüfung
US7854845B2 (en) 2003-09-05 2010-12-21 Hemerus Medical Llc Biological fluid filtration apparatus
US8271139B2 (en) * 2003-10-17 2012-09-18 Asahi Kasei Bioprocess, Inc. Multi-stage accurate blending system and method
US6904370B1 (en) 2003-12-30 2005-06-07 Compliance Software Solutions Corp. System, method, and computer-readable medium for collection of environmental data and generation of user report for compliance with FDA requirements
JP2007522926A (ja) 2004-02-18 2007-08-16 ユー・エス・フィルター・ウェイストウォーター・グループ・インコーポレイテッド 連続的な圧力減衰試験
US7017623B2 (en) * 2004-06-21 2006-03-28 Forhealth Technologies, Inc. Automated use of a vision system to unroll a label to capture and process drug identifying indicia present on the label
US20080000830A1 (en) 2004-08-10 2008-01-03 Kimihiro Mabuchi Highly Water Permeable Hollow Fiber Membrane Type Blood Purifier and Process for Manufacturing the Same
KR101301457B1 (ko) 2004-08-31 2013-08-29 필름텍 코포레이션 분리 모듈의 시험 방법
US7592178B2 (en) 2005-02-23 2009-09-22 Hunter Menufacturing Co. Filter integrity tester
US8337700B1 (en) 2005-02-24 2012-12-25 Hemerus Medical, Llc High capacity biological fluid filtration apparatus
CA2612891A1 (en) 2005-06-22 2007-01-04 Gambro Bct, Inc. Apparatus and method for separating discrete volumes of a composite liquid
EP1898973B2 (en) 2005-07-01 2019-08-21 Gambro Lundia AB Apparatus for testing a filter
CN100491205C (zh) * 2005-08-25 2009-05-27 湖南千山制药机械股份有限公司 间歇旋转式非pvc大输液软袋的固体药灌封机
US7650805B2 (en) 2005-10-11 2010-01-26 Millipore Corporation Integrity testable multilayered filter device
SG131861A1 (en) 2005-10-11 2007-05-28 Millipore Corp Methods and systems for integrity testing of porous materials
US7998349B2 (en) 2005-10-11 2011-08-16 Millipore Corporation Integrity testable multilayered filter device
JP4771785B2 (ja) * 2005-10-25 2011-09-14 東洋自動機株式会社 エアバッグ付き袋への気体封入方法及びエアバッグ付き袋の包装方法
EP1954565B1 (en) * 2005-11-28 2012-10-24 PDC Facilities, Inc. Filling machine
ATE477438T1 (de) 2006-04-07 2010-08-15 Nxstage Medical Inc Schlauchklemme für medizinische anwendungen
US20070243113A1 (en) 2006-04-12 2007-10-18 Dileo Anthony Filter with memory, communication and concentration sensor
US8007568B2 (en) 2006-04-12 2011-08-30 Millipore Corporation Filter with memory, communication and pressure sensor
US20110094310A1 (en) 2006-04-12 2011-04-28 Millipore Corporation Filter with memory, communication and pressure sensor
US7770434B2 (en) * 2006-04-27 2010-08-10 General Electric Company System and method for in-process integrity test of a filter
US20080093277A1 (en) 2006-06-13 2008-04-24 John Armour Cadence detection in a sequence of video fields
US20090173685A1 (en) 2006-06-16 2009-07-09 Terumo Kabushiki Kaisha Blood treatment filter and blood treatment circuit
US8003768B1 (en) 2006-07-05 2011-08-23 Decon Labs, Inc. System for providing 20% ethanol solutions that meet bioburden and endotoxin requirements
ES2263402B1 (es) 2006-07-28 2007-09-16 Grifols, S.A. Dispositivo para la manipulacion de liquidos de perfusion.
US8151835B2 (en) 2006-08-23 2012-04-10 Fht, Inc. Automated drug delivery bag filling system
ITBO20060619A1 (it) 2006-08-30 2008-02-29 Tema Sinergie S R L Macchina automatica per frazionare un liquido radioattivo.
US8366855B2 (en) * 2006-09-12 2013-02-05 Ppi Technologies Global, Llc Automated machine and method for mounting a fitment to a flexible pouch
US20080105618A1 (en) 2006-10-27 2008-05-08 Mesosystems Technology, Inc. Method and apparatus for the removal of harmful contaminants from portable drinking water devices
FR2909904B1 (fr) 2006-12-19 2009-12-11 Degremont Procede de controle de l'integrite de membranes de filtration et dispositif pour la mise en oeuvre de ce procede.
WO2009006850A1 (en) 2007-07-11 2009-01-15 Guangzhen Meng Hollow fiber membrane or capillary membrane filter and water filtration method using such a filter
US8225824B2 (en) * 2007-11-16 2012-07-24 Intelligent Hospital Systems, Ltd. Method and apparatus for automated fluid transfer operations
GB0802216D0 (en) 2008-02-07 2008-03-12 Hammersmith Imanet Ltd GMP dispenser for non-controlled environments
US20090299651A1 (en) 2008-05-29 2009-12-03 Hach Company Filtration testing system
US9821105B2 (en) 2008-07-01 2017-11-21 Baxter International Inc. Nanoclay sorbents for dialysis
US8075550B2 (en) * 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US8172823B2 (en) * 2008-07-03 2012-05-08 Baxter International Inc. Port assembly for use with needleless connector
CA2734919C (en) 2008-08-27 2016-08-16 Schering Corporation Lyophilized formulations of engineered anti-il-23p19 antibodies
US7972515B1 (en) 2008-10-10 2011-07-05 The United States Of America As Represented By The Secretary Of The Navy In situ membrane integrity test
DE102008057458B4 (de) 2008-11-14 2012-04-26 Sartorius Stedim Biotech Gmbh Verfahren und Vorrichtung zur Durchführung von Integritätstests
US8214159B2 (en) 2008-12-04 2012-07-03 Siemens Medical Solutions Usa, Inc. Apparatus and method for automated quality control
EP2253367B1 (en) 2009-05-20 2014-11-19 Gambro Lundia AB Membranes having improved performance
KR20110021286A (ko) 2009-08-26 2011-03-04 코오롱인더스트리 주식회사 정수기용 중공사막 모듈
US8689610B2 (en) 2009-09-24 2014-04-08 W. L. Gore & Associates, Inc. Integrity test method for porous filters
JP6199557B2 (ja) 2009-10-12 2017-09-20 ニュー ヘルス サイエンシーズ、インク．Ｎｅｗ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 酸素及び二酸化炭素の減損能力をもつ血液保存袋システム及び減損装置
FR2956092B1 (fr) 2010-02-10 2012-02-24 Sartorius Stedim Biotech Sa Procede et unite d'emplissage sterile d'un conteneur elementaire final avec un contenu destine au domaine biopharmaceutique.
CN201643862U (zh) 2010-04-20 2010-11-24 新乡平原航空技术工程有限公司 滤芯结构完整性检测装置
CN101816846A (zh) 2010-04-30 2010-09-01 贵州科伦药业有限公司 无菌过滤装置
EP2537141B1 (en) 2010-06-10 2016-03-30 Sartorius Stedim Biotech GmbH Assembling method, operating method, augmented reality system and computer program product
CN102313691A (zh) 2010-07-08 2012-01-11 广州珠江啤酒股份有限公司 单支滤芯反向泡点测试仪及其测试方法
CN201732014U (zh) 2010-08-20 2011-02-02 伊马莱富（北京）制药系统有限公司 无菌过滤器在线完整性测试系统
US8499919B2 (en) * 2010-08-30 2013-08-06 Health Robotics, S.r.l. Machine for the production of pharmaceutical products
EP2425886B1 (en) 2010-09-06 2016-06-29 Sartorius Stedim Biotech GmbH Filter device test apparatus, filter integrity testing method and computer program product
DE102010041826A1 (de) 2010-09-30 2012-04-05 Krones Aktiengesellschaft Verfahren und Vorrichtung zum Herstellen von gefilterten Flüssigkeiten
CN102109364B (zh) 2010-12-01 2012-05-23 上海共和真空技术有限公司 一种用于冻干机的过滤器完整性检测系统及其检测方法
FR2968197B1 (fr) 2010-12-01 2013-12-20 Sartorius Stedim Biotech Sa Poche flexible a usage biopharmaceutique ayant une pluralite de ports de sortie.
DE202010017082U1 (de) 2010-12-08 2011-05-12 ITM Isotopen Technologien München AG Vorrichtung zur Markierung von Molekülen mit Radionukliden und Verwendung derselben zur Herstellung einer radiopharmazeutischen Verbindung
CN201939752U (zh) 2010-12-21 2011-08-24 天津市塑料研究所 脑室外引流瓶
WO2012092394A1 (en) 2010-12-29 2012-07-05 Cardinal Health 414, Llc Closed vial fill system for aseptic dispensing
ES2545998T3 (es) 2010-12-30 2015-09-17 Ge Healthcare Limited Dispensación multivial
CN103384819B (zh) 2011-01-24 2016-04-27 Emd密理博公司 多孔材料的加速混合气体完整性测试
EP2684551B1 (en) * 2011-03-09 2021-10-06 Terumo Kabushiki Kaisha System for delivering oxygen carrier, oxygenation device for oxygen carrier, and housing for oxygen carrier
ITBO20110149A1 (it) 2011-03-23 2012-09-24 Health Robotics Srl Metodo per la preparazione di prodotti farmaceutici
DE102011006545A1 (de) 2011-03-31 2012-10-04 Krones Ag Verfahren zum Überprüfen eines Membranfiltrationsmoduls einer Filtrationsanlage
DE202011102490U1 (de) 2011-04-07 2012-06-28 Klosterfrau Berlin Gmbh Sterilisation von medizinischen Instrumenten für die Injektion und/oder Instillation
US8851127B2 (en) 2011-05-02 2014-10-07 Express Scripts, Inc. Methods and systems for pharmaceutical compounding
US9073650B2 (en) 2011-07-11 2015-07-07 Life Technologies Corporation Fluid manifold systems
DE102011111050B4 (de) 2011-08-24 2013-10-17 Sartorius Stedim Biotech Gmbh Verfahren zum Testen der Integrität eines hydrophoben, porösen Membranfilters
JP5389885B2 (ja) 2011-10-05 2014-01-15 株式会社タカギ 浄水装置
CN102435224B (zh) 2011-11-08 2013-08-07 上海东富龙科技股份有限公司 一种过滤器在线完整性测试方法
CN102430340B (zh) 2011-11-15 2013-09-18 天津瑞普生物技术股份有限公司 一种超滤膜膜包的完整性检测方法
US8962553B2 (en) 2011-11-17 2015-02-24 Cebix Ab Method of treating a diabetic subject having a microvascular impairment disorder by a pegylated C-peptide
ES2504117T3 (es) 2011-12-23 2014-10-08 Barokes Pty Ltd. Vino envasado en recipientes de aluminio
KR102027519B1 (ko) 2011-12-23 2019-10-08 인텔리전트 패키징 피티와이 엘티디 와인이 채워진 알루미늄 컨테이너
US9498753B2 (en) 2012-03-15 2016-11-22 Koch Membrane Systems, Inc. Method for sealing hollow fiber membranes
KR102080539B1 (ko) 2012-06-11 2020-02-24 브라이언 이. 부터스 유체 여과용 장치, 시스템 및 방법
US20150298995A1 (en) 2012-06-28 2015-10-22 Bwt Ag Filter and method of ultrafiltration
EP2869903B1 (en) 2012-07-06 2018-11-28 3-D Matrix Ltd. Fill-finish process for peptide solutions
WO2014018880A1 (en) 2012-07-26 2014-01-30 Zaxis, Inc. Integrated safety and motion control testing device
FR2994162B1 (fr) 2012-08-06 2014-09-05 Thea Lab Tete de distribution de liquide, notamment pour flacon de conditionnement d'un liquide a distribuer goutte a goutte
US8534120B1 (en) 2012-09-14 2013-09-17 Advanced Scientifics, Inc. Test system and method for flexible containers
DE102012216772A1 (de) 2012-09-19 2014-03-20 Krones Aktiengesellschaft Überprüfung eines Membranmoduls einer Filtrationsanlage
SG11201503712TA (en) 2012-12-03 2015-06-29 Emd Millipore Corp Methods and devices used for redundant sterile filtration
EP2931311A4 (en) 2012-12-13 2016-08-17 Merck Sharp & Dohme LYOPHILIZED BALLULAR PELLETS OF ANTI-IL-23 ANTIBODIES
JP2014128780A (ja) 2012-12-27 2014-07-10 Nihon Medi Physics Co Ltd フィルター完全性試験機構を備えた薬液分注機
BR112015015236A2 (pt) * 2012-12-27 2017-07-11 Medi Physics Inc conjunto de conduto de teste de integridade dupla de filtro duplo, e, método para dispensar um líquido de produto
US9772252B2 (en) 2013-02-27 2017-09-26 Ethicon, Inc. Leakage detection in a medical device
FR3003550B1 (fr) * 2013-03-22 2016-05-06 Sartorius Stedim North America Inc Installation et procede pour la preparation d'un conteneur charge avec un fluide biopharmaceutique.
CN203337507U (zh) 2013-06-08 2013-12-11 南京拓鉒医药科技有限公司 一种滤膜完整性的检测装置
US9707521B2 (en) 2013-08-01 2017-07-18 Institute Of Nuclear Energy Research Automated test apparatus for testing risk and integrity of pharmaceutical filtration membranes and method thereof
CN103393542B (zh) 2013-08-12 2016-06-15 浙江信纳医疗器械科技有限公司 一种过滤式输液袋
EP2840379B1 (en) 2013-08-13 2019-05-08 Institute of Nuclear Energy Research, Atomic An automated test method for testing risk and integrity of pharmaceutical filtration membranes
CN105451848B (zh) 2013-08-15 2018-01-26 3M创新有限公司 用于生物医药应用的过滤元件和过滤组件
JP6228802B2 (ja) 2013-10-07 2017-11-08 花王株式会社 袋状容器の充填装置、袋状容器の充填方法および袋状包装体の製造方法
CN203493987U (zh) 2013-10-08 2014-03-26 成都市新津事丰医疗器械有限公司 精密过滤袋式输液器
FR3014330B1 (fr) 2013-12-05 2017-03-24 Abc Membranes Procede de controle de l'integrite de membranes de filtration durant leur fonctionnement
JP6585615B2 (ja) * 2014-03-21 2019-10-02 ライフ テクノロジーズ コーポレイション 流体処理システムのための凝縮器システム
BR122022000294B1 (pt) * 2014-03-21 2022-08-16 Life Technologies Corporation Montagem de filtragem e método para filtrar um gás
CN203740155U (zh) * 2014-03-25 2014-07-30 高瑞灏 中药灌装装置
CN104048839B (zh) 2014-05-26 2016-08-24 上海东富龙拓溥科技有限公司 一种全自动灭菌后在线完整性检测装置及方法
DE102014012784A1 (de) 2014-08-29 2016-03-03 Sartorius Stedim Biotech Gmbh Verfahren und Vorrichtung zur Durchführung einer Integritätsprüfung eines Filterelements
DE102014113638B4 (de) 2014-09-22 2017-11-16 Sartorius Stedim Biotech Gmbh Vorrichtung zur Entlüftung und Integritätstestung
SG11201703291XA (en) 2014-12-30 2017-05-30 Emd Millipore Corp Aseptic filter vent valve and port for integrity testing
US9636648B2 (en) 2015-02-19 2017-05-02 Asahi Kasei Bioprocess, Inc. System and method for compensating binary inlet buffers during inline buffer diluation
DE202015101765U1 (de) 2015-04-10 2015-04-23 Sartorius Stedim Biotech Gmbh Integritätstestvorrichtung für Filtermodule
CN204797991U (zh) 2015-07-01 2015-11-25 宋静 一次性使用内镜或腔镜下烟雾过滤导管
CN204988705U (zh) 2015-09-11 2016-01-20 上海东富龙拓溥科技有限公司 一种应用隔离罐的配液系统滤芯在线完整性测试系统
CN204910247U (zh) 2015-09-11 2015-12-30 中日友好医院 一种急救胸腔闭式引流装置
CN205262990U (zh) 2015-12-25 2016-05-25 曼胡默尔滤清器（上海）有限公司 一种检验圆筒形空滤滤芯完整性的装置
EP3195921A1 (en) 2016-01-22 2017-07-26 Gambro Lundia AB Filter membrane and device

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