HU184141B - Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof - Google Patents

Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof Download PDF

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Publication number
HU184141B
HU184141B HU79HU299A HUHU000299A HU184141B HU 184141 B HU184141 B HU 184141B HU 79HU299 A HU79HU299 A HU 79HU299A HU HU000299 A HUHU000299 A HU HU000299A HU 184141 B HU184141 B HU 184141B
Authority
HU
Hungary
Prior art keywords
particles
biologically active
aqueous electrolyte
electrolyte solution
water
Prior art date
Application number
HU79HU299A
Other languages
German (de)
English (en)
Hungarian (hu)
Inventor
Zoltan Riedl
Laszlo Sztankov
Istvan Horvath
Original Assignee
Human Oltoanyagtermelo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Oltoanyagtermelo filed Critical Human Oltoanyagtermelo
Priority to HU79HU299A priority Critical patent/HU184141B/hu
Priority to CH9166/80A priority patent/CH655246A5/de
Priority to US06/218,126 priority patent/US4396630A/en
Priority to ES80498048A priority patent/ES8201316A1/es
Priority to PT72261A priority patent/PT72261B/pt
Priority to SE8009068A priority patent/SE453537B/sv
Priority to PL22875580A priority patent/PL228755A1/xx
Priority to DE19803048815 priority patent/DE3048815A1/de
Priority to GB804281A priority patent/GB2066203B/en
Priority to CS809246A priority patent/CS241478B2/cs
Priority to DK552280A priority patent/DK160288C/da
Priority to NL8007041A priority patent/NL8007041A/nl
Priority to CA000367565A priority patent/CA1165237A/en
Priority to IT26950/80A priority patent/IT1150073B/it
Priority to FR8027496A priority patent/FR2472386B1/fr
Priority to RO80102952A priority patent/RO81371A/ro
Priority to JP55184157A priority patent/JPS57112334A/ja
Priority to YU3290/80A priority patent/YU44413B/xx
Priority to SU803220898A priority patent/SU1487802A3/ru
Priority to BE0/203337A priority patent/BE886884A/fr
Priority to DD81227326A priority patent/DD158738A5/de
Publication of HU184141B publication Critical patent/HU184141B/hu

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU79HU299A 1979-12-27 1979-12-27 Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof HU184141B (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
HU79HU299A HU184141B (en) 1979-12-27 1979-12-27 Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
CH9166/80A CH655246A5 (de) 1979-12-27 1980-12-12 Verfahren zur herstellung von partikeln aus lipoidloeslichen stoffen.
US06/218,126 US4396630A (en) 1979-12-27 1980-12-19 Process for preparing lipoid-biologically active particles
ES80498048A ES8201316A1 (es) 1979-12-27 1980-12-22 Procedimiento de preparar agentes de utilidad clinica a par-tir de substancias solubles en lipoides
PT72261A PT72261B (en) 1979-12-27 1980-12-22 Particles of lipoid-soluble substances compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
SE8009068A SE453537B (sv) 1979-12-27 1980-12-22 Sett att framstella blandningar innehallande partiklar av lipoidlosliga substanser och vid dessa bundna biologiskt aktiva substanser
PL22875580A PL228755A1 (2) 1979-12-27 1980-12-23
DE19803048815 DE3048815A1 (de) 1979-12-27 1980-12-23 Teilchen aus lipoidloeslichen stoffen, aus diesen teilchen und an diese gebundenen, biologisch aktiven stoffen bestehende gemische sowie verfahren zu deren herstellung
GB804281A GB2066203B (en) 1979-12-27 1980-12-23 Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
CS809246A CS241478B2 (en) 1979-12-27 1980-12-23 Carrier system's particles and method of their production
DK552280A DK160288C (da) 1979-12-27 1980-12-23 Fremgangsmaade til fremstilling af liposomer, til hvilke der er bundet biologisk aktive substanser
NL8007041A NL8007041A (nl) 1979-12-27 1980-12-24 Deeltjes van vet-oplosbare stoffen, preparaten die deze deeltjes en biologisch actieve stoffen daarop geadsorbeerd bevatten alsmede een werkwijze voor de bereiding daarvan.
CA000367565A CA1165237A (en) 1979-12-27 1980-12-24 Particles of lipoid-soluble substances, compositions containing said particles and biologically active substances adsorbed thereon, and a process for the preparation thereof
IT26950/80A IT1150073B (it) 1979-12-27 1980-12-24 Particelle di sostanze solubili in lipoidi e composizioni biologicamente attive che le contengono
FR8027496A FR2472386B1 (2) 1979-12-27 1980-12-24
RO80102952A RO81371A (ro) 1979-12-27 1980-12-25 Procedeu de preparare a unui suport lipoid solubil destinat legarii substantelor biologice active
JP55184157A JPS57112334A (en) 1979-12-27 1980-12-26 Particles of lipid soluble substance, composition consisting of particles and biologically active substance adsorbed with particles and their manufacture
YU3290/80A YU44413B (en) 1979-12-27 1980-12-26 Process for obtaining particles of matter soluble in lipoids and biologcally active substances adsorbed thereon
SU803220898A SU1487802A3 (ru) 1979-12-27 1980-12-26 Способ получения липосом
BE0/203337A BE886884A (fr) 1979-12-27 1980-12-29 Particules de substances liposolubles, compositions contenant ces particules et des substances biologiquement actives adsorbees sur celles-ci, et procede pour leur preparation
DD81227326A DD158738A5 (de) 1979-12-27 1981-01-30 Verfahren zur herstellung von partikeln aus lipoidloeslichen stoffen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79HU299A HU184141B (en) 1979-12-27 1979-12-27 Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof

Publications (1)

Publication Number Publication Date
HU184141B true HU184141B (en) 1984-07-30

Family

ID=10997378

Family Applications (1)

Application Number Title Priority Date Filing Date
HU79HU299A HU184141B (en) 1979-12-27 1979-12-27 Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof

Country Status (21)

Country Link
US (1) US4396630A (2)
JP (1) JPS57112334A (2)
BE (1) BE886884A (2)
CA (1) CA1165237A (2)
CH (1) CH655246A5 (2)
CS (1) CS241478B2 (2)
DD (1) DD158738A5 (2)
DE (1) DE3048815A1 (2)
DK (1) DK160288C (2)
ES (1) ES8201316A1 (2)
FR (1) FR2472386B1 (2)
GB (1) GB2066203B (2)
HU (1) HU184141B (2)
IT (1) IT1150073B (2)
NL (1) NL8007041A (2)
PL (1) PL228755A1 (2)
PT (1) PT72261B (2)
RO (1) RO81371A (2)
SE (1) SE453537B (2)
SU (1) SU1487802A3 (2)
YU (1) YU44413B (2)

Families Citing this family (52)

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US4598051A (en) * 1980-03-12 1986-07-01 The Regents Of The University Of California Liposome conjugates and diagnostic methods therewith
US4806466A (en) * 1981-10-29 1989-02-21 The Regents Of The University Of California Cell agglutination reagent comprising conjugates of antibody covalently bound to liposomes
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
DD247570A3 (de) * 1983-01-14 1987-07-15 Univ Berlin Humboldt Vesikulaeres trenn-, fuell- und traegermaterial
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US5059591B1 (en) * 1983-05-26 2000-04-25 Liposome Co Inc Drug preparations of reduced toxicity
US4708861A (en) * 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
US5916588A (en) * 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
US6090406A (en) * 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
GB2160312B (en) * 1984-04-13 1987-09-16 South African Inventions Adjuvant for immunisation
PT78628B (en) * 1984-05-02 1986-06-18 Liposome Co Inc Pharmaceutical composition with reduced toxicity
US4619904A (en) * 1984-10-29 1986-10-28 General Electric Company Agglutinating immunoassay using protein-coated liquid droplets
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US5266329A (en) * 1985-10-31 1993-11-30 Kv Pharmaceutical Company Vaginal delivery system
ATE68686T1 (de) * 1985-10-31 1991-11-15 Kv Pharm Co System zum freigeben von stoffen in der vagina.
US4790987A (en) * 1985-11-15 1988-12-13 Research Corporation Viral glycoprotein subunit vaccine
CA1338736C (fr) * 1986-12-05 1996-11-26 Roger Baurain Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation
US5688519A (en) * 1987-04-06 1997-11-18 Leonard; Robert J. Flash-flow fused medicinal implants
US4748024A (en) * 1987-04-06 1988-05-31 Endocon, Inc. Flash flow fused medicinal implants
WO1990001948A1 (en) * 1988-08-25 1990-03-08 The Liposome Company, Inc. Influenza vaccine and novel adjuvants
DE3852950T2 (de) * 1988-12-22 1995-06-14 Baxter Diagnostics Inc Lipohaptene und Verwendung trägergebundener Lipohaptene im Immuntest.
US5100662A (en) * 1989-08-23 1992-03-31 The Liposome Company, Inc. Steroidal liposomes exhibiting enhanced stability
JPH07113641B2 (ja) * 1989-11-17 1995-12-06 積水化学工業株式会社 梅毒診断試薬の製造方法
NL9000207A (2) * 1990-01-29 1991-08-16 Duphar Int Res
US5709879A (en) * 1990-06-29 1998-01-20 Chiron Corporation Vaccine compositions containing liposomes
FI925835A0 (fi) * 1990-06-29 1992-12-22 Chiron Corp Vacciner innehaollande liposomer
IE912535A1 (en) * 1990-07-27 1992-01-29 Res Dev Foundation Liposomes that Provide Thymic Dependent Help to Weak Vaccine¹Antigens
WO1992004887A1 (fr) * 1990-09-25 1992-04-02 Kyowa Hakko Kogyo Co., Ltd. Production de lymphocites t cytotoxiques
US6048531A (en) * 1991-04-15 2000-04-11 Albany Medical College Immunogenic composites capable of stimulating production of anti-peptide antibodies, pharmaceutical compositions employing these composites and methods of selectively inducing production of anti-peptide antibodies
US5336507A (en) * 1992-12-11 1994-08-09 Sterling Winthrop Inc. Use of charged phospholipids to reduce nanoparticle aggregation
GB9320668D0 (en) * 1993-10-07 1993-11-24 Secr Defence Liposomes containing particulare materials
AUPM500494A0 (en) * 1994-04-12 1994-05-05 Minister For Agriculture & Rural Affairs For The State Of New South Wales, The Composition for use in increasing mucosal immunity
SK7092003A3 (en) * 2000-11-09 2004-06-08 Neopharm Inc SN-38 lipid complexes and methods of use
WO2003030864A1 (en) * 2001-05-29 2003-04-17 Neopharm, Inc. Liposomal formulation of irinotecan
WO2003075889A1 (en) * 2002-03-05 2003-09-18 Transave, Inc. An inhalation system for prevention and treatment of intracellular infections
AU2003296897A1 (en) * 2002-08-20 2004-05-04 Neopharm, Inc. Pharmaceutical formulations of camptothecine derivatives
US20060030578A1 (en) * 2002-08-20 2006-02-09 Neopharm, Inc. Pharmaceutically active lipid based formulation of irinotecan
EP1581236B1 (en) * 2002-10-29 2013-10-16 Insmed Incorporated Sustained release of antiinfectives
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
KR100651728B1 (ko) * 2004-11-10 2006-12-06 한국전자통신연구원 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법
WO2006090816A1 (ja) * 2005-02-25 2006-08-31 Mie University リポソームワクチンの作製法
HUE029994T2 (en) 2005-12-08 2017-04-28 Insmed Inc Lipid-based compositions of antiinfectives for treating pulmonary infections
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
MX369828B (es) 2012-05-21 2019-11-22 Insmed Inc Sistemas para tratar infecciones pulmonares.
RU2018135921A (ru) 2012-11-29 2019-02-05 Инсмед Инкорпорейтед Стабилизированные составы ванкомицина
SMT202000516T1 (it) 2014-05-15 2020-11-10 Insmed Inc Metodi per trattamento di infezioni micobatteriche polmonati non tubercolari
EP3773505B1 (en) 2018-03-30 2026-04-29 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
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GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
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FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
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JPS55118415A (en) * 1979-02-28 1980-09-11 Pii Papahadojiyopo Dometoriosu Method of encapsulating biologically active substance in lipoid cell

Also Published As

Publication number Publication date
JPH0314814B2 (2) 1991-02-27
SU1487802A3 (ru) 1989-06-15
IT1150073B (it) 1986-12-10
DD158738A5 (de) 1983-02-02
PT72261A (en) 1981-01-01
RO81371A (ro) 1984-04-02
YU329080A (en) 1984-04-30
DK160288C (da) 1991-08-05
CA1165237A (en) 1984-04-10
BE886884A (fr) 1981-06-29
PT72261B (en) 1981-11-05
DK160288B (da) 1991-02-25
SE8009068L (sv) 1981-06-28
ES498048A0 (es) 1981-12-16
CH655246A5 (de) 1986-04-15
DK552280A (da) 1981-06-28
YU44413B (en) 1990-08-31
GB2066203A (en) 1981-07-08
GB2066203B (en) 1984-01-11
CS924680A2 (en) 1985-07-16
SE453537B (sv) 1988-02-08
JPS57112334A (en) 1982-07-13
PL228755A1 (2) 1982-02-15
DE3048815A1 (de) 1981-09-10
IT8026950A0 (it) 1980-12-24
US4396630A (en) 1983-08-02
RO81371B (ro) 1983-11-02
ES8201316A1 (es) 1981-12-16
NL8007041A (nl) 1981-07-16
FR2472386B1 (2) 1985-08-23
FR2472386A1 (2) 1981-07-03
CS241478B2 (en) 1986-03-13

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HU90 Patent valid on 900628