HU187355B - Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives - Google Patents

Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives Download PDF

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Publication number
HU187355B
HU187355B HU812482A HU248281A HU187355B HU 187355 B HU187355 B HU 187355B HU 812482 A HU812482 A HU 812482A HU 248281 A HU248281 A HU 248281A HU 187355 B HU187355 B HU 187355B
Authority
HU
Hungary
Prior art keywords
amino
hydroxy
halo
halogenation
substituted pyrimidine
Prior art date
Application number
HU812482A
Other languages
English (en)
Hungarian (hu)
Inventor
Andras Vedres
Judit Horvath
Laszlo Ladanyi
Tamas Mester
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU812482A priority Critical patent/HU187355B/hu
Priority to FI822818A priority patent/FI822818L/fi
Priority to GB08223902A priority patent/GB2107309B/en
Priority to ES82515190A priority patent/ES8306479A1/es
Priority to BE1/10578A priority patent/BE894193A/fr
Priority to IT22986/82A priority patent/IT1190971B/it
Priority to FR8214695A priority patent/FR2512021B1/fr
Priority to CH5100/82A priority patent/CH648833A5/de
Priority to JP57149042A priority patent/JPS5874671A/ja
Priority to SU823484882A priority patent/SU1132789A3/ru
Publication of HU187355B publication Critical patent/HU187355B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU812482A 1981-08-28 1981-08-28 Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives HU187355B (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
HU812482A HU187355B (en) 1981-08-28 1981-08-28 Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives
FI822818A FI822818L (fi) 1981-08-28 1982-08-12 Foerfarande att framstaella 2-amino-4-hydroxi-5-halogen-pyrimidin
GB08223902A GB2107309B (en) 1981-08-28 1982-08-19 Preparation of 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives
ES82515190A ES8306479A1 (es) 1981-08-28 1982-08-23 "procedimiento de obtencion de 2-amino-4-hidroxi-5-halogenopirimidinas".
BE1/10578A BE894193A (fr) 1981-08-28 1982-08-25 Procede de preparation de 2-amino-4-hydroxy-5-halogeno pyrimidines
IT22986/82A IT1190971B (it) 1981-08-28 1982-08-26 Procedimento per la produzione di 2-ammino-4-idrossi-5-alogeno-pirimidine
FR8214695A FR2512021B1 (fr) 1981-08-28 1982-08-27 Procede de preparation de 2-amino-4-hydroxy-5-halogeno-pyrimidines
CH5100/82A CH648833A5 (de) 1981-08-28 1982-08-27 Verfahren zur herstellung von 2-amino-4-hydroxy-5-halogen-pyrimidinen.
JP57149042A JPS5874671A (ja) 1981-08-28 1982-08-27 ２−アミノ−４−ヒドロキシ−５−ハロ置換ピリミジン誘導体の製造法
SU823484882A SU1132789A3 (ru) 1981-08-28 1982-08-28 Способ получени 2-амино-4-гидрокси-5-галогенпиримидинов

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU812482A HU187355B (en) 1981-08-28 1981-08-28 Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives

Publications (1)

Publication Number Publication Date
HU187355B true HU187355B (en) 1985-12-28

Family

ID=10959594

Family Applications (1)

Application Number Title Priority Date Filing Date
HU812482A HU187355B (en) 1981-08-28 1981-08-28 Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives

Country Status (10)

Country Link
JP (1) JPS5874671A (fr)
BE (1) BE894193A (fr)
CH (1) CH648833A5 (fr)
ES (1) ES8306479A1 (fr)
FI (1) FI822818L (fr)
FR (1) FR2512021B1 (fr)
GB (1) GB2107309B (fr)
HU (1) HU187355B (fr)
IT (1) IT1190971B (fr)
SU (1) SU1132789A3 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495558B1 (en) 1999-01-22 2002-12-17 Amgen Inc. Kinase inhibitors
CA2359680A1 (fr) * 1999-01-22 2000-07-27 David M. Armistead Inhibiteurs de kinase

Also Published As

Publication number Publication date
BE894193A (fr) 1983-02-25
CH648833A5 (de) 1985-04-15
FI822818A7 (fi) 1983-03-01
IT8222986A0 (it) 1982-08-26
SU1132789A3 (ru) 1984-12-30
IT8222986A1 (it) 1984-02-26
FR2512021B1 (fr) 1985-08-09
IT1190971B (it) 1988-02-24
FI822818A0 (fi) 1982-08-12
ES515190A0 (es) 1983-06-01
GB2107309B (en) 1985-05-30
ES8306479A1 (es) 1983-06-01
GB2107309A (en) 1983-04-27
FI822818L (fi) 1983-03-01
JPS5874671A (ja) 1983-05-06
FR2512021A1 (fr) 1983-03-04

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee