JPS5874671A - 2−アミノ−4−ヒドロキシ−5−ハロ置換ピリミジン誘導体の製造法 - Google Patents

2−アミノ−4−ヒドロキシ−5−ハロ置換ピリミジン誘導体の製造法

Info

Publication number
JPS5874671A
JPS5874671A JP57149042A JP14904282A JPS5874671A JP S5874671 A JPS5874671 A JP S5874671A JP 57149042 A JP57149042 A JP 57149042A JP 14904282 A JP14904282 A JP 14904282A JP S5874671 A JPS5874671 A JP S5874671A
Authority
JP
Japan
Prior art keywords
hydroxy
solution
amino
general formula
carried out
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57149042A
Other languages
English (en)
Japanese (ja)
Inventor
アンドラス・ベドレス
ユデイツト・ホルバス
ラスズロ・ラダンイ
タマス・メステル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of JPS5874671A publication Critical patent/JPS5874671A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57149042A 1981-08-28 1982-08-27 2−アミノ−4−ヒドロキシ−5−ハロ置換ピリミジン誘導体の製造法 Pending JPS5874671A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU812482A HU187355B (en) 1981-08-28 1981-08-28 Process for preparing 2-amino-4-hydroxy-5-halo-substituted pyrimidine derivatives
HU2251/2482/81 1982-10-01

Publications (1)

Publication Number Publication Date
JPS5874671A true JPS5874671A (ja) 1983-05-06

Family

ID=10959594

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57149042A Pending JPS5874671A (ja) 1981-08-28 1982-08-27 2−アミノ−4−ヒドロキシ−5−ハロ置換ピリミジン誘導体の製造法

Country Status (10)

Country Link
JP (1) JPS5874671A (fr)
BE (1) BE894193A (fr)
CH (1) CH648833A5 (fr)
ES (1) ES8306479A1 (fr)
FI (1) FI822818A7 (fr)
FR (1) FR2512021B1 (fr)
GB (1) GB2107309B (fr)
HU (1) HU187355B (fr)
IT (1) IT1190971B (fr)
SU (1) SU1132789A3 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495558B1 (en) 1999-01-22 2002-12-17 Amgen Inc. Kinase inhibitors
CA2359680A1 (fr) * 1999-01-22 2000-07-27 David M. Armistead Inhibiteurs de kinase

Also Published As

Publication number Publication date
ES515190A0 (es) 1983-06-01
IT8222986A0 (it) 1982-08-26
GB2107309B (en) 1985-05-30
SU1132789A3 (ru) 1984-12-30
FR2512021B1 (fr) 1985-08-09
FI822818L (fi) 1983-03-01
BE894193A (fr) 1983-02-25
FR2512021A1 (fr) 1983-03-04
CH648833A5 (de) 1985-04-15
HU187355B (en) 1985-12-28
FI822818A7 (fi) 1983-03-01
FI822818A0 (fi) 1982-08-12
ES8306479A1 (es) 1983-06-01
IT1190971B (it) 1988-02-24
IT8222986A1 (it) 1984-02-26
GB2107309A (en) 1983-04-27

Similar Documents

Publication Publication Date Title
JPH0329791B2 (fr)
JPH0579055B2 (fr)
JPS62238236A (ja) アルコキシサリチル酸誘導体の製造方法
JPS62169755A (ja) テトラクロロ−2−シアノ安息香酸アルキルエステルの製造方法
Lewis et al. The Oxidation of Tetramethyl-1, 3-bis-(p-tolyl)-disiloxane to 1, 3-Bis-(p-carboxyphenyl)-tetramethyldisiloxane
JPS6148403A (ja) ヨウ化アルカリの製法
GB2107309A (en) Preparation of 2-amino-4- hydroxy-5-halo-substituted pyrimidine derivatives
US4351776A (en) Preparation of iodophthalonitrile
JPS5828259B2 (ja) フロログルシン及びその誘導体の製法
JPS6236366A (ja) 2−シアノアミノ−ピリミジン誘導体の製造方法
JPS63170384A (ja) 7α置換セフアロスポリン化合物
JPS6339893A (ja) 5−フルオロウリジン類およびその製法
JPS62481A (ja) ニトロフタライド類の製法
JPH0832681B2 (ja) 2−ヨ−ドブチロフエノン誘導体およびその製造法
JP2004067543A (ja) N−アルコキシエチル脂環式アンモニウム塩及びその製造法
JP3443584B2 (ja) N−tert−ブチルピラジンカルボキサミド類の製造方法
JPH0776206B2 (ja) アゾ化合物複合体
JPH01258649A (ja) 2,4−ジクロロ−3−アルキル−6−ニトロフェノールの製造方法
CN115894348A (zh) 一种2,5-二溴吡啶的制备方法
JPS62145065A (ja) 5−クロロ及び5−ブロモ−2−ヒドロキシニコチン酸の製造方法
McMaster et al. A New Synthesis of 5-Benzyl-8-hydroxyquinoline and the Antiseptic Activity of its Sulfate
JPH0129789B2 (fr)
JPS63277678A (ja) 放射性2−ブロモブチロフェノン誘導体およびその製造法
JPH1095793A (ja) 抗腫瘍性白金錯体カルボプラチンの製造方法
JPH03157362A (ja) ベンジルハライド類