HU195855B - Process for production of ll-e 33288-marked antibioticumkomplex and its components with antitumor effect and medical compositions containing them - Google Patents

Process for production of ll-e 33288-marked antibioticumkomplex and its components with antitumor effect and medical compositions containing them Download PDF

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Publication number
HU195855B
HU195855B HU854365A HU436585A HU195855B HU 195855 B HU195855 B HU 195855B HU 854365 A HU854365 A HU 854365A HU 436585 A HU436585 A HU 436585A HU 195855 B HU195855 B HU 195855B
Authority
HU
Hungary
Prior art keywords
ethyl acetate
following
saturated
aqueous potassium
potassium dihydrogen
Prior art date
Application number
HU854365A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT41839A (en
Inventor
May D Lee
Michael Greenstein
David P Labeda
Amedeo A Fantini
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of HUT41839A publication Critical patent/HUT41839A/hu
Publication of HU195855B publication Critical patent/HU195855B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Hydrogenated Pyridines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HU854365A 1984-11-16 1985-11-15 Process for production of ll-e 33288-marked antibioticumkomplex and its components with antitumor effect and medical compositions containing them HU195855B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67203184A 1984-11-16 1984-11-16
US78706685A 1985-10-17 1985-10-17

Publications (2)

Publication Number Publication Date
HUT41839A HUT41839A (en) 1987-05-28
HU195855B true HU195855B (en) 1988-07-28

Family

ID=27100668

Family Applications (1)

Application Number Title Priority Date Filing Date
HU854365A HU195855B (en) 1984-11-16 1985-11-15 Process for production of ll-e 33288-marked antibioticumkomplex and its components with antitumor effect and medical compositions containing them

Country Status (19)

Country Link
EP (1) EP0182152B1 (2)
JP (1) JPH0774228B2 (2)
KR (1) KR890001289B1 (2)
AT (1) ATE180513T1 (2)
AU (1) AU589918B2 (2)
CA (1) CA1291054C (2)
DE (1) DE3588213T2 (2)
DK (1) DK168388B1 (2)
EG (1) EG17709A (2)
ES (1) ES8703160A1 (2)
FI (1) FI86892C (2)
GR (1) GR852725B (2)
HU (1) HU195855B (2)
IL (7) IL76878A (2)
LV (1) LV12523B (2)
MX (1) MX9203146A (2)
NO (1) NO163574C (2)
NZ (1) NZ214114A (2)
PT (1) PT81493B (2)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3440423A1 (de) * 1984-11-06 1986-05-07 Dr. Karl Thomae Gmbh, 7950 Biberach Antibiotisches polypeptid, verfahren zu seiner herstellung, dieses polypeptid erzeugender stamm von staphylococcus epidermidis, dieses polypeptid enthaltende zubereitungsformen und seine verwendung zur bekaempfung infektioeser erkrankungen
US5024948A (en) * 1985-10-17 1991-06-18 American Cyanamid Company Genetic system for micromonospora
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4980297A (en) * 1987-02-27 1990-12-25 Becton, Dickinson And Company Device for the membrane separation of the components of a liquid sample
ES2061586T3 (es) * 1987-10-30 1994-12-16 American Cyanamid Co Analogos disulfuricos de agentes antitumorales ll-e33288.
EP0330874A3 (en) * 1988-02-29 1989-10-18 American Cyanamid Company Antibacterial and antitumor agents LL-E33288 epsilon-I and LL-E33288-epsilonBr, with processes and intermediates for producing said agents
US4978748A (en) * 1988-02-29 1990-12-18 American Cyanamid Company Intermediate and process for producing the antibacterial and antitumor agents LL-E33288ε-I and LL-E33288Epsilon-Br
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
US4977143A (en) * 1988-02-29 1990-12-11 American Cyanamid Company Antibacterial and antitumor agents LL-E33288EPSILON-I and LL-E33288EPSILON-BR
EP0342341A3 (en) * 1988-05-17 1991-07-24 American Cyanamid Company Process for producing antitumor antibiotic ll-e33288gamma2
EP0405151A1 (en) * 1989-06-29 1991-01-02 American Cyanamid Company Antibiotic LL-E19085
CN109553646A (zh) * 2019-01-21 2019-04-02 浙江海正药业股份有限公司 一种纯化卡里奇霉素的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU515150B2 (en) * 1975-02-18 1981-03-19 Sterling Drug Inc. Preparation of aminocyclitol antibiotics
GR77567B (2) * 1982-08-26 1984-09-24 Lepetit Spa
US4843008A (en) * 1984-12-24 1989-06-27 Yamanouchi Pharmaceutical Co., Ltd. Novel microorganisms and a novel process for producing antibiotics

Also Published As

Publication number Publication date
JPS61158928A (ja) 1986-07-18
KR890001289B1 (ko) 1989-04-28
EP0182152A3 (en) 1987-08-05
FI854510A0 (fi) 1985-11-15
ES8703160A1 (es) 1987-02-16
DE3588213D1 (de) 1999-07-01
NO854578L (no) 1986-05-20
DE3588213T2 (de) 1999-09-30
PT81493B (pt) 1987-11-11
AU589918B2 (en) 1989-10-26
IL93421A0 (en) 1990-11-29
AU4995785A (en) 1986-05-22
NZ214114A (en) 1989-04-26
DK168388B1 (da) 1994-03-21
LV12523B (en) 2000-11-20
CA1291054C (en) 1991-10-22
IL93420A0 (en) 1990-11-29
IL93418A0 (en) 1990-11-29
FI854510L (fi) 1986-05-17
EP0182152A2 (en) 1986-05-28
GR852725B (2) 1986-03-19
PT81493A (en) 1985-12-01
MX9203146A (es) 1992-07-01
ATE180513T1 (de) 1999-06-15
NO163574B (no) 1990-03-12
HUT41839A (en) 1987-05-28
HK1011385A1 (en) 1999-07-09
DK529685D0 (da) 1985-11-15
FI86892C (fi) 1992-10-26
JPH0774228B2 (ja) 1995-08-09
IL93419A0 (en) 1990-11-29
NO163574C (no) 1990-06-20
FI86892B (fi) 1992-07-15
EP0182152B1 (en) 1999-05-26
IL76878A0 (en) 1986-02-28
DK529685A (da) 1986-05-17
KR870004144A (ko) 1987-05-07
ES548953A0 (es) 1987-02-16
LV12523A (en) 2000-08-20
IL93416A0 (en) 1990-11-29
IL93417A0 (en) 1990-11-29
EG17709A (en) 1990-08-30
IL76878A (en) 1991-12-15

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628