ID16375A - Derivat-derivat imidazole yang dilebur sebagai modulator-modulator resistensi bermacam-macam obat - Google Patents

Derivat-derivat imidazole yang dilebur sebagai modulator-modulator resistensi bermacam-macam obat

Info

Publication number: ID16375A
Authority: ID; Indonesia
Prior art keywords: mixed; drug resistance; various drug; resistance modulators; imidazole derivates
Prior art date: 1996-03-19

Application number

IDP970888A

Other languages

English (en)

Indonesian (id)

Inventor

Frans Eduard Janssens

Joseph Elisabeth Leenaerts

Francois Maria Sommen

Dominique Louis Nest Surleraux

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-19

Filing date

1997-03-19

Publication date

1997-09-25

1997-03-19 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1997-09-25 Publication of ID16375A publication Critical patent/ID16375A/id

Links

RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 2
206010059866 Drug resistance Diseases 0.000 title 1
RAXXELZNTBOGNW-UHFFFAOYSA-O Imidazolium Chemical compound C1=C[NH+]=CN1 RAXXELZNTBOGNW-UHFFFAOYSA-O 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Tropical Medicine & Parasitology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

IDP970888A 1996-03-19 1997-03-19 Derivat-derivat imidazole yang dilebur sebagai modulator-modulator resistensi bermacam-macam obat ID16375A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP96200755		1996-03-19

Publications (1)

Publication Number	Publication Date
ID16375A true ID16375A (id)	1997-09-25

Family

ID=8223797

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDP970888A ID16375A (id)	1996-03-19	1997-03-19	Derivat-derivat imidazole yang dilebur sebagai modulator-modulator resistensi bermacam-macam obat

Country Status (29)

Country	Link
US (3)	US6218381B1 (de)
EP (1)	EP0888352B1 (de)
JP (3)	JP3630434B2 (de)
KR (2)	KR100330698B1 (de)
CN (1)	CN1083453C (de)
AR (1)	AR006271A1 (de)
AT (1)	ATE241626T1 (de)
BG (1)	BG62734B1 (de)
BR (1)	BR9708140A (de)
CA (1)	CA2237594C (de)
CZ (1)	CZ294060B6 (de)
DE (1)	DE69722389T2 (de)
EA (1)	EA001004B1 (de)
EE (1)	EE03773B1 (de)
ES (1)	ES2200159T3 (de)
HR (1)	HRP970161B1 (de)
HU (1)	HU224528B1 (de)
ID (1)	ID16375A (de)
IL (1)	IL124572A (de)
MX (1)	MX9804426A (de)
MY (1)	MY118282A (de)
NO (1)	NO310659B1 (de)
NZ (1)	NZ330466A (de)
PL (1)	PL193444B1 (de)
SK (1)	SK284434B6 (de)
TR (1)	TR199801191T2 (de)
TW (1)	TW527186B (de)
WO (1)	WO1997034897A1 (de)
ZA (1)	ZA972351B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1146099A (en) *	1997-09-18	1999-04-05	Janssen Pharmaceutica N.V.	Fused imidazole derivatives for improving oral bioavailability of pharmaceuticalagents
DE69931617T2 (de) *	1998-04-01	2007-05-24	Jagotec Ag	Taxan-mikroemulsionen
US6743794B2 (en)	1999-12-22	2004-06-01	Eli Lilly And Company	Methods and compounds for inhibiting MRP1
US6376514B1 (en)	2000-10-17	2002-04-23	The Procter & Gamble Co.	Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
US6693099B2 (en)	2000-10-17	2004-02-17	The Procter & Gamble Company	Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance
WO2002100862A2 (en)	2001-06-12	2002-12-19	Janssen Pharmaceutica N.V.	Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine
WO2003044023A1 (en) *	2001-11-23	2003-05-30	Janssen Pharmaceutica N.V.	The use of anti-histaminics for acute reduction of elevated intracranial pressure
GB0301736D0 (en) *	2003-01-24	2003-02-26	Xenova Ltd	Pharmaceutical compounds
EP2978765B1 (de) *	2013-03-25	2018-05-02	Crystal Pharma S.A.U	Verfahren zur herstellung von alcaftadin
CN103408549B (zh) *	2013-06-14	2016-01-20	苏州汇和药业有限公司	一种阿卡他定中间体的制备方法

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DE2418502C3 (de) *	1974-04-11	1980-04-24	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Dichlorbenzyl- [2-( a -imidazolylbutyl)-phenyl] -äther und -thioäther, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4153719A (en) *	1977-09-06	1979-05-08	Sterling Drug Inc.	Aromatic diketones
JPS56125326A (en) *	1980-03-07	1981-10-01	Asahi Kagaku Kogyo Kk	Preparation of chlorinated phenoxytoluenes in high selectivity
US4567184A (en)	1982-12-01	1986-01-28	Usv Pharmaceutical Corporation	Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies
US4794188A (en)	1982-12-01	1988-12-27	Usv Pharmaceutical Corporation	Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity
US4778931A (en)	1982-12-01	1988-10-18	Usv Pharmaceutical Corporation	Certain [3-(1-hydroxy hexyl-tetrahydro)naphthalenes], the corresponding naphthalenes having anti-inflammatory and anti-allergic activity
US4588722A (en)	1984-01-09	1986-05-13	Janssen Pharmaceutica N.V.	N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
JPS61151176A (ja) *	1984-12-24	1986-07-09	Sumitomo Chem Co Ltd	ベンズイミダゾール誘導体およびそれを有効成分とする殺虫、殺ダニ剤
US4631287A (en) *	1985-04-16	1986-12-23	Usv Pharmaceutical Corp.	Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments
US4840971A (en) *	1986-04-07	1989-06-20	Sumitomo Chemical Company, Limited	Novel ether compound, a process for manufacturing the same, a composition containing the same and a use thereof
JPS6475441A (en) *	1987-09-16	1989-03-22	Sumitomo Chemical Co	Production of optically active ether compound
JPH01254680A (ja) *	1988-04-01	1989-10-11	Sumitomo Chem Co Ltd	複素環化合物、その製造法およびそれを有効成分とする殺菌剤
EP0552292B1 (de) *	1990-10-10	1995-06-21	Schering Corporation	Substituierte imidazobenzazepine und imidazopyridoazepine
IL101851A (en)	1991-06-13	1996-05-14	Janssen Pharmaceutica Nv	10-(4-piperidinyl- and piperidinylidene)-imidazo [1,2-a] (pyrrolo thieno or furano) [2,3] azepine derivatives their preparation and pharmaceutical compositions containing them and certain novel intermediates therefor
IL101850A (en)	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
GB9122590D0 (en) *	1991-10-24	1991-12-04	Lilly Industries Ltd	Pharmaceutical compounds
DK0643693T3 (da) *	1992-02-06	1999-11-29	Merrell Pharma Inc	Reversering af multi-lægemiddelresistens med triphenyl-piperidin-derivater
CA2150805C (en)	1992-12-04	2006-08-15	Frans Eduard Janssens	Antiallergic imidazo[1,2-a](pyrrolo, thieno or furano)[2,3-d]azepine derivatives
JPH08508270A (ja) *	1993-03-29	1996-09-03	ビーエーエスエフアクチエンゲゼルシャフト	マルチ・ドラッグ耐性のモジュレーターとしての１−アミノ−３−フェノキシ−プロパン誘導体
EP0708776B1 (de)	1993-07-13	2001-01-03	Janssen Pharmaceutica N.V.	Antiallergische imidazoazepine
US5486612A (en) *	1993-12-14	1996-01-23	Eli Lilly And Company	N-benzyl dihydroindole LTD4 antagonists
US5596008A (en) *	1995-02-10	1997-01-21	G. D. Searle & Co.	3,4-Diaryl substituted pyridines for the treatment of inflammation
FR2731708B1 (fr)	1995-03-13	1997-04-30	Synthelabo	Derives de piperidine, leur procede de preparation et leur application en therapeutique
TW382017B (en)	1995-12-27	2000-02-11	Janssen Pharmaceutica Nv	1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives

1997
- 1997-03-05 TW TW086102623A patent/TW527186B/zh not_active IP Right Cessation
- 1997-03-11 DE DE69722389T patent/DE69722389T2/de not_active Expired - Fee Related
- 1997-03-11 EP EP97908226A patent/EP0888352B1/de not_active Expired - Lifetime
- 1997-03-11 ES ES97908226T patent/ES2200159T3/es not_active Expired - Lifetime
- 1997-03-11 BR BR9708140A patent/BR9708140A/pt not_active IP Right Cessation
- 1997-03-11 HU HU9900415A patent/HU224528B1/hu not_active IP Right Cessation
- 1997-03-11 IL IL12457297A patent/IL124572A/en not_active IP Right Cessation
- 1997-03-11 NZ NZ330466A patent/NZ330466A/xx unknown
- 1997-03-11 PL PL97327985A patent/PL193444B1/pl not_active IP Right Cessation
- 1997-03-11 CN CN97192399A patent/CN1083453C/zh not_active Expired - Fee Related
- 1997-03-11 KR KR1019980703754A patent/KR100330698B1/ko not_active Expired - Fee Related
- 1997-03-11 US US09/142,932 patent/US6218381B1/en not_active Expired - Fee Related
- 1997-03-11 AT AT97908226T patent/ATE241626T1/de not_active IP Right Cessation
- 1997-03-11 JP JP53312197A patent/JP3630434B2/ja not_active Expired - Fee Related
- 1997-03-11 CZ CZ19981529A patent/CZ294060B6/cs not_active IP Right Cessation
- 1997-03-11 TR TR1998/01191T patent/TR199801191T2/xx unknown
- 1997-03-11 SK SK662-98A patent/SK284434B6/sk not_active IP Right Cessation
- 1997-03-11 KR KR1020017008287A patent/KR100349500B1/ko not_active Expired - Fee Related
- 1997-03-11 WO PCT/EP1997/001264 patent/WO1997034897A1/en not_active Ceased
- 1997-03-11 EA EA199800586A patent/EA001004B1/ru unknown
- 1997-03-11 CA CA002237594A patent/CA2237594C/en not_active Expired - Fee Related
- 1997-03-11 EE EE9800281A patent/EE03773B1/xx not_active IP Right Cessation
- 1997-03-17 MY MYPI97001123A patent/MY118282A/en unknown
- 1997-03-18 ZA ZA972351A patent/ZA972351B/xx unknown
- 1997-03-18 AR ARP970101072A patent/AR006271A1/es unknown
- 1997-03-19 HR HR970161A patent/HRP970161B1/xx not_active IP Right Cessation
- 1997-03-19 ID IDP970888A patent/ID16375A/id unknown
1998
- 1998-05-11 NO NO19982124A patent/NO310659B1/no not_active IP Right Cessation
- 1998-05-18 BG BG102459A patent/BG62734B1/bg unknown
- 1998-06-03 MX MX9804426A patent/MX9804426A/es not_active IP Right Cessation
2001
- 2001-02-02 US US09/775,524 patent/US6476018B1/en not_active Expired - Fee Related
- 2001-06-01 JP JP2001167003A patent/JP4205319B2/ja not_active Expired - Fee Related
2002
- 2002-07-02 US US10/187,665 patent/US20030087895A1/en not_active Abandoned
2003
- 2003-10-08 JP JP2003349802A patent/JP4251447B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN1083453C (zh)	2002-04-24
EE9800281A (et)	1999-02-15
MX9804426A (es)	1998-09-30
JP2002012594A (ja)	2002-01-15
HRP970161B1 (en)	2002-06-30
ZA972351B (en)	1998-09-18
CA2237594C (en)	2006-05-30
PL193444B1 (pl)	2007-02-28
SK66298A3 (en)	1999-06-11
EA199800586A1 (ru)	1998-12-24
JP3630434B2 (ja)	2005-03-16
NZ330466A (en)	1999-03-29
PL327985A1 (en)	1999-01-04
US6476018B1 (en)	2002-11-05
NO982124D0 (no)	1998-05-11
KR20000064358A (ko)	2000-11-06
TW527186B (en)	2003-04-11
JP2004067701A (ja)	2004-03-04
HRP970161A2 (en)	1998-04-30
SK284434B6 (sk)	2005-04-01
NO982124L (no)	1998-09-18
HK1015769A1 (en)	1999-10-22
IL124572A (en)	2002-03-10
AU709683B2 (en)	1999-09-02
EE03773B1 (et)	2002-06-17
BG62734B1 (bg)	2000-06-30
EP0888352A1 (de)	1999-01-07
HUP9900415A3 (en)	2001-11-28
DE69722389D1 (de)	2003-07-03
DE69722389T2 (de)	2009-09-24
HU224528B1 (hu)	2005-10-28
CA2237594A1 (en)	1997-09-25
BR9708140A (pt)	1999-07-27
TR199801191T2 (xx)	1998-10-21
JP4251447B2 (ja)	2009-04-08
CZ152998A3 (cs)	1999-02-17
KR100349500B1 (ko)	2002-08-21
EP0888352B1 (de)	2003-05-28
US20030087895A1 (en)	2003-05-08
IL124572A0 (en)	1998-12-06
US6218381B1 (en)	2001-04-17
CN1211985A (zh)	1999-03-24
NO310659B1 (no)	2001-08-06
HUP9900415A2 (hu)	1999-05-28
ATE241626T1 (de)	2003-06-15
AU2026997A (en)	1997-10-10
EA001004B1 (ru)	2000-08-28
AR006271A1 (es)	1999-08-11
CZ294060B6 (cs)	2004-09-15
ES2200159T3 (es)	2004-03-01
BG102459A (en)	1999-06-30
MY118282A (en)	2004-09-30
JP2000505477A (ja)	2000-05-09
JP4205319B2 (ja)	2009-01-07
KR100330698B1 (ko)	2002-10-31
WO1997034897A1 (en)	1997-09-25

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DE69818053D1 (de)	2003-10-16	Gefüllte polymerzusammensetzungen
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NO20000857D0 (no)	2000-02-21	Mikseapparat
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ATE226599T1 (de)	2002-11-15	Homogener gefüllter polymerverbundwerkstoff
FI973529L (fi)	1997-11-25	Askomysiinejä
ID29268A (id)	2001-08-16	Senyawa spiro yang bersifat antihistamin
ID16154A (id)	1997-09-04	Komposisi monomer yang distabilisasi
DE59814478D1 (de)	2011-02-03	Kehlmaschine
DE69625733D1 (de)	2003-02-20	Verbesserte Polymerpulverstabilität
ATE241626T1 (de)	2003-06-15	Kondensierte imidazolderivate als modulatoren vielfacher medikamentenresistenz
ID16910A (id)	1997-11-20	Asetilena biaril-asetilena biaril sebagai penghambat-penghambat matriks metaloproteasa-matriks metaloproteasa
ID17442A (id)	1997-12-24	Campuran-campuran pewarna
NO995492D0 (no)	1999-11-10	Algicider
FR2750243B1 (fr)	2002-10-25	Cable mixte
FR2745486B1 (fr)	1999-08-06	Pied de mixage
FR2743905B1 (fr)	1999-03-05	Composition de revelateur organique-inorganique
FR2748382B3 (fr)	1998-09-25	Pied de mixage
AU5688999A (en)	2000-03-21	Formamide compounds as therapeutic agents
DE69621795D1 (de)	2002-07-18	Mischen