ID22984A - Proses epoksidasi selektif untuk pembuatan senyawa farmasi - Google Patents

Proses epoksidasi selektif untuk pembuatan senyawa farmasi

Info

Publication number
ID22984A
ID22984A IDW990901A ID990901A ID22984A ID 22984 A ID22984 A ID 22984A ID W990901 A IDW990901 A ID W990901A ID 990901 A ID990901 A ID 990901A ID 22984 A ID22984 A ID 22984A
Authority
ID
Indonesia
Prior art keywords
pharmaceutical compounds
epoxidation process
making pharmaceutical
selective epoxidation
selective
Prior art date
Application number
IDW990901A
Other languages
English (en)
Indonesian (id)
Inventor
Vinod Francis Patel
David Warren Hoard
Eric David Moher
Bryan Hurst Norman
Original Assignee
Eli Lilly And Company Cs
Univ Hawaii
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company Cs, Univ Hawaii, Univ Wayne State filed Critical Eli Lilly And Company Cs
Publication of ID22984A publication Critical patent/ID22984A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/46Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IDW990901A 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi ID22984A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3911497P 1997-02-26 1997-02-26
US3911697P 1997-02-26 1997-02-26

Publications (1)

Publication Number Publication Date
ID22984A true ID22984A (id) 1999-12-23

Family

ID=26715826

Family Applications (2)

Application Number Title Priority Date Filing Date
IDW990901A ID22984A (id) 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi
IDW990900D ID24527A (id) 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi

Family Applications After (1)

Application Number Title Priority Date Filing Date
IDW990900D ID24527A (id) 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi

Country Status (17)

Country Link
US (1) US6143909A (fr)
EP (2) EP0861838A3 (fr)
JP (2) JP2002513403A (fr)
KR (2) KR20000075623A (fr)
CN (2) CN1252788A (fr)
AU (2) AU6667198A (fr)
BR (2) BR9807265A (fr)
CA (2) CA2281104A1 (fr)
CZ (1) CZ9902998A3 (fr)
EA (2) EA002547B1 (fr)
ID (2) ID22984A (fr)
IL (2) IL131162A0 (fr)
NO (2) NO994049D0 (fr)
NZ (1) NZ336918A (fr)
PL (2) PL335347A1 (fr)
TR (2) TR199902064T2 (fr)
WO (2) WO1998038158A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4233997A (en) * 1996-08-30 1998-03-19 Eli Lilly And Company Process for preparing pharmaceutical compounds
JP2001506970A (ja) * 1996-09-06 2001-05-29 イーライ・リリー・アンド・カンパニー 方法及び新規な中間体
AU1123200A (en) * 1998-10-16 2000-05-08 Eli Lilly And Company Stereoselective process for producing antineoplastic agents
WO2000034252A2 (fr) * 1998-12-07 2000-06-15 Eli Lilly And Company Procede de crotylboration permettant de produire des composes de cryptophycine
WO2000034253A2 (fr) * 1998-12-07 2000-06-15 Eli Lilly And Company Procede de crotylboration permettant de produire des antineoplasiques et des antifongiques
CA2385528C (fr) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions et methodes de traitement du cancer utilisant des immunoconjugues et des agents chimiotherapeutiques
US7229814B2 (en) * 2004-05-05 2007-06-12 Regents Of The University Of Minnesota Nucleic acids and polypeptides involved in the production of cryptophycin
CN101962323B (zh) * 2010-07-16 2013-06-05 中国人民解放军第二军医大学 2-丙烯酰x基-3-取代苯基丙酸类化合物及其用途
CN111333560B (zh) * 2020-04-13 2024-01-23 合肥工业大学 一种制备螺环β-内酰胺的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946835A (en) * 1988-07-15 1990-08-07 Merck & Co., Inc. Antifungal fermentation product and method
US4868208A (en) * 1988-07-15 1989-09-19 Merck & Co., Inc. Antifungal agent and method
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
DE69020143T2 (de) * 1989-02-17 1996-01-25 Chiron Mimotopes Pty Ltd Verfahren zur verwendung und herstellung von peptiden.
US5256802A (en) * 1990-04-03 1993-10-26 Miles Inc. Process for the production of oxiranes
NZ257077A (en) * 1992-11-06 1997-05-26 Chiron Mimotopes Pty Ltd Support for synthesis of modular polymers
GB2282384B8 (en) * 1993-08-18 1997-09-04 Europ Economic Community Drug delivery agents incorporating mitomycin
CA2179490A1 (fr) * 1993-12-21 1995-06-29 Trimurtulu Golakoti Nouvelles cryptophycines
US5952298A (en) * 1993-12-21 1999-09-14 The University Of Hawaii Cryptophycins
AU723652B2 (en) * 1993-12-21 2000-08-31 University Of Hawaii New cryptophycins from synthesis
JPH10509429A (ja) * 1994-10-14 1998-09-14 ストラティジーン ポリヌクレオチドのポルフィリン標識
DE69624235T2 (de) * 1995-03-31 2003-06-26 Nippon Chemiphar Co. Ltd., Tokio/Tokyo Derivate der epoxybernsteinsäure
US5700826A (en) * 1995-06-07 1997-12-23 Ontogen Corporation 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
EP0850057A4 (fr) * 1995-08-30 2001-04-11 Lilly Co Eli Composes pharmaceutiques
ES2194129T3 (es) * 1995-12-22 2003-11-16 Univ Hawaii Compuestos farmaceuticos.
AU724312B2 (en) * 1996-02-07 2000-09-14 Buckman Laboratories International, Inc. Synergistic antimicrobial compositions containing an ionene polymer and a salt of dodecylamine and methods of using the same
ES2156338T3 (es) * 1996-02-27 2001-06-16 Lilly Co Eli Derivados de criptoficina y su uso como agentes antimicrotubulos.
CA2264297A1 (fr) * 1996-08-30 1998-03-05 Chuan Shih Composes pharmaceutiques
CA2264063C (fr) * 1996-08-30 2007-03-13 Eli Lilly And Company Composes de cryptophycine
JP2001502297A (ja) * 1996-08-30 2001-02-20 イーライ・リリー・アンド・カンパニー 医薬用化合物
US6025506A (en) * 1997-02-21 2000-02-15 Dsm N.V. Process for preparing an optically active phenylglycidyl acid derivative
TW438787B (en) * 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester

Also Published As

Publication number Publication date
CA2281108A1 (fr) 1998-09-03
ID24527A (id) 2000-07-20
JP2002512603A (ja) 2002-04-23
BR9807265A (pt) 2000-05-23
EP0861839A1 (fr) 1998-09-02
PL335478A1 (en) 2000-04-25
BR9811252A (pt) 2000-09-26
CN1252788A (zh) 2000-05-10
TR199902065T2 (xx) 2000-02-21
US6143909A (en) 2000-11-07
EP0861838A3 (fr) 1998-12-09
TR199902064T2 (xx) 2001-10-22
AU6667298A (en) 1998-09-18
EP0861838A2 (fr) 1998-09-02
WO1998038158A1 (fr) 1998-09-03
WO1998038164A1 (fr) 1998-09-03
CN1255121A (zh) 2000-05-31
CZ9902998A3 (cs) 2002-10-16
AU738999B2 (en) 2001-10-04
NZ336918A (en) 2001-11-30
AU6667198A (en) 1998-09-18
NO994049L (no) 1999-08-23
NO994083D0 (no) 1999-08-24
EA199900770A1 (ru) 2000-04-24
KR20000075671A (ko) 2000-12-26
EA002547B1 (ru) 2002-06-27
IL131162A0 (en) 2001-01-28
JP2002513403A (ja) 2002-05-08
EA199900772A1 (ru) 2000-04-24
KR20000075623A (ko) 2000-12-26
CA2281104A1 (fr) 1998-09-03
IL131205A0 (en) 2001-01-28
NO994083L (no) 1999-10-25
PL335347A1 (en) 2000-04-25
NO994049D0 (no) 1999-08-23

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