ID25776A - Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin - Google Patents

Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin

Info

Publication number
ID25776A
ID25776A IDW20000997D ID20000997D ID25776A ID 25776 A ID25776 A ID 25776A ID W20000997 D IDW20000997 D ID W20000997D ID 20000997 D ID20000997 D ID 20000997D ID 25776 A ID25776 A ID 25776A
Authority
ID
Indonesia
Prior art keywords
hydrohalogenides
flourofenil
indola
butil
isobenzofuran
Prior art date
Application number
IDW20000997D
Other languages
English (en)
Indonesian (id)
Inventor
Niels Mork
Heidi Lopez De Diego
Ole Nielsen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of ID25776A publication Critical patent/ID25776A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IDW20000997D 1997-11-07 1998-11-06 Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin ID25776A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK126797 1997-11-07

Publications (1)

Publication Number Publication Date
ID25776A true ID25776A (id) 2000-11-02

Family

ID=8102935

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000997D ID25776A (id) 1997-11-07 1998-11-06 Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin

Country Status (38)

Country Link
US (2) US6844352B2 (de)
EP (1) EP1044202B1 (de)
JP (1) JP3605358B2 (de)
KR (1) KR100399274B1 (de)
CN (1) CN1105115C (de)
AR (1) AR023010A1 (de)
AT (1) ATE288918T1 (de)
AU (1) AU749094B2 (de)
BG (1) BG64906B1 (de)
BR (1) BR9813949A (de)
CA (1) CA2308745C (de)
CZ (1) CZ288666B6 (de)
DE (1) DE69828999T2 (de)
DZ (1) DZ2642A1 (de)
EA (1) EA002092B1 (de)
EG (1) EG23791A (de)
ES (1) ES2234162T3 (de)
HR (1) HRP20000261B1 (de)
HU (1) HUP0100991A3 (de)
ID (1) ID25776A (de)
IL (1) IL135723A (de)
IS (1) IS2342B (de)
JO (1) JO2052B1 (de)
MA (1) MA25585A1 (de)
NO (1) NO325920B1 (de)
NZ (1) NZ504065A (de)
PE (1) PE130299A1 (de)
PL (1) PL190538B1 (de)
PT (1) PT1044202E (de)
RS (1) RS49777B (de)
SK (1) SK285245B6 (de)
TN (1) TNSN98201A1 (de)
TR (1) TR200001267T2 (de)
TW (1) TW483894B (de)
UA (1) UA64769C2 (de)
UY (1) UY25236A1 (de)
WO (1) WO1999024436A1 (de)
ZA (1) ZA9810116B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002013789A1 (en) * 2000-08-15 2002-02-21 H. Lundbeck A/S Pharmaceutical composition containing 1'-[4-[1-(4-fluorophenyl)-1h-indole-3-yl] -1-butyl]-spiro[isobenzofuran-1(3h),4'-piperidine]
WO2004026855A1 (en) * 2002-09-20 2004-04-01 H. Lundbeck A/S Method for manufacture of dihydroisobenzofuran derivatives
EP1644026A4 (de) 2003-06-12 2007-10-24 Ms Science Corp Sigma-liganden für die neuronale regeneration und funktionale erholung
EP1913378A1 (de) * 2005-07-29 2008-04-23 Sigma-Aldrich Production GmbH Ionisierungsadditive enthaltende lc/ms-blends
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
US20070244143A1 (en) * 2006-03-08 2007-10-18 Braincells, Inc Modulation of neurogenesis by nootropic agents
US20100216734A1 (en) * 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US20100009983A1 (en) * 2006-05-09 2010-01-14 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2382975A3 (de) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenese mittels Angiotensin-Modulation
JP2009536667A (ja) * 2006-05-09 2009-10-15 ブレインセルス,インコーポレイティド 5ht受容体介在性の神経新生
AU2007292848A1 (en) * 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
AU2007299920A1 (en) * 2006-09-19 2008-03-27 Braincells, Inc. PPAR Mediated Modulation of Neurogenesis
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109002A (en) * 1989-09-08 1992-04-28 Du Pont Merck Pharmaceutical Company Antipsychotic 1-cycloalkylpiperidines
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
BG104485A (en) 2001-01-31
TNSN98201A1 (fr) 2005-03-15
US20030055074A1 (en) 2003-03-20
DE69828999D1 (de) 2005-03-17
CN1278823A (zh) 2001-01-03
CN1105115C (zh) 2003-04-09
DE69828999T2 (de) 2005-07-21
TR200001267T2 (tr) 2000-09-21
US6844352B2 (en) 2005-01-18
YU23500A (sh) 2003-12-31
NO20002188L (no) 2000-06-14
CA2308745C (en) 2004-01-20
NO20002188D0 (no) 2000-04-27
AU1022699A (en) 1999-05-31
PT1044202E (pt) 2005-04-29
EP1044202A1 (de) 2000-10-18
UA64769C2 (uk) 2004-03-15
BG64906B1 (bg) 2006-08-31
HRP20000261A2 (en) 2001-04-30
JO2052B1 (en) 1999-05-15
EP1044202B1 (de) 2005-02-09
HUP0100991A3 (en) 2003-03-28
JP2001522852A (ja) 2001-11-20
UY25236A1 (es) 2000-12-29
AR023010A1 (es) 2002-09-04
DZ2642A1 (fr) 2004-12-28
SK285245B6 (sk) 2006-09-07
CZ20001663A3 (cs) 2000-10-11
ZA9810116B (en) 1999-05-07
IL135723A (en) 2005-11-20
HUP0100991A2 (hu) 2001-09-28
EG23791A (en) 2007-08-13
MA25585A1 (fr) 2002-12-31
RS49777B (sr) 2008-06-05
ES2234162T3 (es) 2005-06-16
PL190538B1 (pl) 2005-12-30
IS5460A (is) 2000-04-18
KR100399274B1 (ko) 2003-09-26
HRP20000261B1 (en) 2009-04-30
JP3605358B2 (ja) 2004-12-22
PE130299A1 (es) 1999-12-16
IS2342B (is) 2008-02-15
TW483894B (en) 2002-04-21
NZ504065A (en) 2002-05-31
HK1034075A1 (en) 2001-10-12
IL135723A0 (en) 2001-05-20
CA2308745A1 (en) 1999-05-20
KR20010031791A (ko) 2001-04-16
WO1999024436A1 (en) 1999-05-20
PL340220A1 (en) 2001-01-15
BR9813949A (pt) 2000-09-26
CZ288666B6 (cs) 2001-08-15
SK6462000A3 (en) 2000-10-09
ATE288918T1 (de) 2005-02-15
NO325920B1 (no) 2008-08-18
EA200000502A1 (ru) 2000-10-30
US20050171135A1 (en) 2005-08-04
EA002092B1 (ru) 2001-12-24
AU749094B2 (en) 2002-06-20

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