ID25776A - Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin - Google Patents

Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin

Info

Publication number: ID25776A
Authority: ID; Indonesia
Prior art keywords: hydrohalogenides; flourofenil; indola; butil; isobenzofuran
Prior art date: 1997-11-07

Application number

IDW20000997D

Other languages

English (en)

Indonesian (id)

Inventor

Niels Mork

Heidi Lopez De Diego

Ole Nielsen

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-07

Filing date

1998-11-06

Publication date

2000-11-02

1998-11-06 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2000-11-02 Publication of ID25776A publication Critical patent/ID25776A/id

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IDW20000997D 1997-11-07 1998-11-06 Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin ID25776A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK126797		1997-11-07

Publications (1)

Publication Number	Publication Date
ID25776A true ID25776A (id)	2000-11-02

Family

ID=8102935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20000997D ID25776A (id)	1997-11-07	1998-11-06	Hidrohalogenida-hidrohalogenida 1'-(-4-(1-(4-flourofenil)-1-h-indola-3-il)-1-butil)-spiro (isobenzofuran-1(3h),4-piperidin

Country Status (38)

Country	Link
US (2)	US6844352B2 (is)
EP (1)	EP1044202B1 (is)
JP (1)	JP3605358B2 (is)
KR (1)	KR100399274B1 (is)
CN (1)	CN1105115C (is)
AR (1)	AR023010A1 (is)
AT (1)	ATE288918T1 (is)
AU (1)	AU749094B2 (is)
BG (1)	BG64906B1 (is)
BR (1)	BR9813949A (is)
CA (1)	CA2308745C (is)
CZ (1)	CZ288666B6 (is)
DE (1)	DE69828999T2 (is)
DZ (1)	DZ2642A1 (is)
EA (1)	EA002092B1 (is)
EG (1)	EG23791A (is)
ES (1)	ES2234162T3 (is)
HR (1)	HRP20000261B1 (is)
HU (1)	HUP0100991A3 (is)
ID (1)	ID25776A (is)
IL (1)	IL135723A (is)
IS (1)	IS2342B (is)
JO (1)	JO2052B1 (is)
MA (1)	MA25585A1 (is)
NO (1)	NO325920B1 (is)
NZ (1)	NZ504065A (is)
PE (1)	PE130299A1 (is)
PL (1)	PL190538B1 (is)
PT (1)	PT1044202E (is)
RS (1)	RS49777B (is)
SK (1)	SK285245B6 (is)
TN (1)	TNSN98201A1 (is)
TR (1)	TR200001267T2 (is)
TW (1)	TW483894B (is)
UA (1)	UA64769C2 (is)
UY (1)	UY25236A1 (is)
WO (1)	WO1999024436A1 (is)
ZA (1)	ZA9810116B (is)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002013789A1 (en) *	2000-08-15	2002-02-21	H. Lundbeck A/S	Pharmaceutical composition containing 1'-[4-[1-(4-fluorophenyl)-1h-indole-3-yl] -1-butyl]-spiro[isobenzofuran-1(3h),4'-piperidine]
WO2004026855A1 (en) *	2002-09-20	2004-04-01	H. Lundbeck A/S	Method for manufacture of dihydroisobenzofuran derivatives
US20050032827A1 (en) *	2003-06-12	2005-02-10	Donna Oksenberg	Sigma ligands for neuronal regeneration and functional recovery
US20090306341A1 (en) *	2005-07-29	2009-12-10	Joachim Emmert	LC/MS Blends Containing Ionizing Additives
US7985756B2 (en)	2005-10-21	2011-07-26	Braincells Inc.	Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) *	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
CA2643199A1 (en) *	2006-03-08	2007-09-13	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
WO2007134077A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
WO2007134136A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
EP2068872A1 (en) *	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
EP2066355A2 (en) *	2006-09-19	2009-06-10	Braincells, Inc.	Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5109002A (en) *	1989-09-08	1992-04-28	Du Pont Merck Pharmaceutical Company	Antipsychotic 1-cycloalkylpiperidines
NZ243065A (en) *	1991-06-13	1995-07-26	Lundbeck & Co As H	Piperidine derivatives and pharmaceutical compositions

1998
- 1998-06-11 UA UA2000052828A patent/UA64769C2/uk unknown
- 1998-10-20 TW TW087117299A patent/TW483894B/zh not_active IP Right Cessation
- 1998-10-27 MA MA25316A patent/MA25585A1/fr unknown
- 1998-11-03 EG EG136298A patent/EG23791A/xx active
- 1998-11-04 DZ DZ980252A patent/DZ2642A1/xx active
- 1998-11-04 TN TNTNSN98201A patent/TNSN98201A1/fr unknown
- 1998-11-05 AR ARP980105596A patent/AR023010A1/es active IP Right Grant
- 1998-11-05 JO JO19982052A patent/JO2052B1/en active
- 1998-11-05 ZA ZA9810116A patent/ZA9810116B/xx unknown
- 1998-11-05 PE PE1998001067A patent/PE130299A1/es not_active Application Discontinuation
- 1998-11-06 CZ CZ20001663A patent/CZ288666B6/cs not_active IP Right Cessation
- 1998-11-06 EA EA200000502A patent/EA002092B1/ru not_active IP Right Cessation
- 1998-11-06 RS YUP-235/00A patent/RS49777B/sr unknown
- 1998-11-06 UY UY25236A patent/UY25236A1/es not_active IP Right Cessation
- 1998-11-06 ES ES98952580T patent/ES2234162T3/es not_active Expired - Lifetime
- 1998-11-06 HR HR20000261A patent/HRP20000261B1/xx not_active IP Right Cessation
- 1998-11-06 SK SK646-2000A patent/SK285245B6/sk not_active IP Right Cessation
- 1998-11-06 KR KR10-2000-7004858A patent/KR100399274B1/ko not_active Expired - Fee Related
- 1998-11-06 JP JP2000520446A patent/JP3605358B2/ja not_active Expired - Fee Related
- 1998-11-06 CA CA002308745A patent/CA2308745C/en not_active Expired - Fee Related
- 1998-11-06 HU HU0100991A patent/HUP0100991A3/hu unknown
- 1998-11-06 WO PCT/DK1998/000480 patent/WO1999024436A1/en not_active Ceased
- 1998-11-06 PT PT98952580T patent/PT1044202E/pt unknown
- 1998-11-06 AT AT98952580T patent/ATE288918T1/de not_active IP Right Cessation
- 1998-11-06 CN CN98810910A patent/CN1105115C/zh not_active Expired - Fee Related
- 1998-11-06 NZ NZ504065A patent/NZ504065A/en unknown
- 1998-11-06 DE DE69828999T patent/DE69828999T2/de not_active Expired - Fee Related
- 1998-11-06 EP EP98952580A patent/EP1044202B1/en not_active Expired - Lifetime
- 1998-11-06 PL PL98340220A patent/PL190538B1/pl not_active IP Right Cessation
- 1998-11-06 ID IDW20000997D patent/ID25776A/id unknown
- 1998-11-06 BR BR9813949-5A patent/BR9813949A/pt not_active Application Discontinuation
- 1998-11-06 TR TR2000/01267T patent/TR200001267T2/xx unknown
- 1998-11-06 IL IL13572398A patent/IL135723A/xx not_active IP Right Cessation
- 1998-11-06 AU AU10226/99A patent/AU749094B2/en not_active Ceased
2000
- 2000-04-18 IS IS5460A patent/IS2342B/is unknown
- 2000-04-27 NO NO20002188A patent/NO325920B1/no not_active IP Right Cessation
- 2000-05-29 BG BG104485A patent/BG64906B1/bg unknown
2002
- 2002-10-15 US US10/272,403 patent/US6844352B2/en not_active Expired - Fee Related
2004
- 2004-12-13 US US11/012,084 patent/US20050171135A1/en not_active Abandoned

Also Published As

Publication number	Publication date
TNSN98201A1 (fr)	2005-03-15
EP1044202A1 (en)	2000-10-18
IL135723A0 (en)	2001-05-20
JP3605358B2 (ja)	2004-12-22
AU749094B2 (en)	2002-06-20
IS2342B (is)	2008-02-15
CA2308745A1 (en)	1999-05-20
NZ504065A (en)	2002-05-31
HRP20000261A2 (en)	2001-04-30
WO1999024436A1 (en)	1999-05-20
NO325920B1 (no)	2008-08-18
US20030055074A1 (en)	2003-03-20
HRP20000261B1 (en)	2009-04-30
PT1044202E (pt)	2005-04-29
EP1044202B1 (en)	2005-02-09
PL340220A1 (en)	2001-01-15
TR200001267T2 (tr)	2000-09-21
DE69828999D1 (de)	2005-03-17
RS49777B (sr)	2008-06-05
NO20002188L (no)	2000-06-14
BG104485A (en)	2001-01-31
CN1105115C (zh)	2003-04-09
US6844352B2 (en)	2005-01-18
YU23500A (sh)	2003-12-31
KR20010031791A (ko)	2001-04-16
US20050171135A1 (en)	2005-08-04
CZ288666B6 (cs)	2001-08-15
SK285245B6 (sk)	2006-09-07
SK6462000A3 (en)	2000-10-09
EA002092B1 (ru)	2001-12-24
IL135723A (en)	2005-11-20
MA25585A1 (fr)	2002-12-31
AU1022699A (en)	1999-05-31
DE69828999T2 (de)	2005-07-21
JP2001522852A (ja)	2001-11-20
TW483894B (en)	2002-04-21
BR9813949A (pt)	2000-09-26
CA2308745C (en)	2004-01-20
UA64769C2 (uk)	2004-03-15
PL190538B1 (pl)	2005-12-30
IS5460A (is)	2000-04-18
NO20002188D0 (no)	2000-04-27
PE130299A1 (es)	1999-12-16
EA200000502A1 (ru)	2000-10-30
DZ2642A1 (fr)	2004-12-28
HUP0100991A3 (en)	2003-03-28
CZ20001663A3 (cs)	2000-10-11
CN1278823A (zh)	2001-01-03
HUP0100991A2 (hu)	2001-09-28
HK1034075A1 (en)	2001-10-12
ES2234162T3 (es)	2005-06-16
BG64906B1 (bg)	2006-08-31
ZA9810116B (en)	1999-05-07
KR100399274B1 (ko)	2003-09-26
AR023010A1 (es)	2002-09-04
ATE288918T1 (de)	2005-02-15
JO2052B1 (en)	1999-05-15
UY25236A1 (es)	2000-12-29
EG23791A (en)	2007-08-13

Publication	Publication Date	Title
GB9808800D0 (en)	1998-06-24	Well logging instruments
DE69609006D1 (de)	2000-08-03	Tintenstrahldrucktinten
FI955200A7 (fi)	1997-05-01	Yhteiskäytäntö half-duplex -liikennöintiä varten
DE69619943D1 (de)	2002-04-25	Tintenstrahldrucker
EP0843984A4 (en)	1999-10-13	BIDET
DE59606460D1 (de)	2001-03-29	Bohrstange
ATE202105T1 (de)	2001-06-15	8-substituierte-1,3,8-triazaspiro(4,5)decan-4- onderivate
ATE212635T1 (de)	2002-02-15	1,3,8-triazaspiro(4,5)decan-4-on-derivate
MA25585A1 (fr)	2002-12-31	1-[-[1-(4-fluorophenyl)-1h-indole-3-yl]-1- butyl]-spiro[ isobenzofuran- 1(3h),4 -piperidine] hydrohalogenides.
DE69622234D1 (de)	2002-08-14	Tintenstrahldrucker
ATE204279T1 (de)	2001-09-15	Diaza-spiro(3,5)nonan-derivate
DE69617465D1 (de)	2002-01-10	Printer
GB9606582D0 (en)	1996-06-05	Compass saw
SG70655A1 (en)	2000-02-22	New spirocyclic compounds
GB2302295B (en)	1999-03-10	Reamer
GB9606983D0 (en)	1996-06-05	Ultra-violet (u.v) bubble mix
GB9501694D0 (en)	1995-03-15	Stepped tapered leader
AU5300398A (en)	1998-08-13	Guide post driver
SI1044202T1 (en)	2005-04-30	1'- 4- 1- (4-fluorophenyl)- 1h-indole-3-yl) -1-butyl)-spiro isobenzofuran- 1(3h),4'- piperidine) hydrohalogenides
AU6870896A (en)	1997-03-12	Substituted quinazolin(thi)ones
AU717385C (en)	2002-09-19	Guide post
GB2304768B (en)	1999-02-10	Ballasting member
AUPO499397A0 (en)	1997-02-27	Guide post
GB9517373D0 (en)	1995-10-25	Reamer
TW302604U (en)	1997-04-11	Combination type potting set