ID26876A - Derivat-derivat benzotiepin 1,1-dioksida, proses pembuatannya, bahan-bahan farmasi yang terdiri dari senyawa-senyawa ini dan penggunaannya - Google Patents

Derivat-derivat benzotiepin 1,1-dioksida, proses pembuatannya, bahan-bahan farmasi yang terdiri dari senyawa-senyawa ini dan penggunaannya

Info

Publication number
ID26876A
ID26876A IDW20002564A ID20002564A ID26876A ID 26876 A ID26876 A ID 26876A ID W20002564 A IDW20002564 A ID W20002564A ID 20002564 A ID20002564 A ID 20002564A ID 26876 A ID26876 A ID 26876A
Authority
ID
Indonesia
Prior art keywords
benzotiepin
derivates
dioxide
compounds
making
Prior art date
Application number
IDW20002564A
Other languages
English (en)
Inventor
Wendelin Dr Frick
Alfons Dr Enhsen
Heiner Dr Glombik
Hubert Dr Heuer
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of ID26876A publication Critical patent/ID26876A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IDW20002564A 1998-06-10 1999-05-29 Derivat-derivat benzotiepin 1,1-dioksida, proses pembuatannya, bahan-bahan farmasi yang terdiri dari senyawa-senyawa ini dan penggunaannya ID26876A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19825804A DE19825804C2 (de) 1998-06-10 1998-06-10 1,4-Benzothiepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ID26876A true ID26876A (id) 2001-02-15

Family

ID=7870440

Family Applications (2)

Application Number Title Priority Date Filing Date
IDW20002562A ID28695A (id) 1998-06-10 1999-05-28 TURUNAN-TURUNAN BENZO (b) TIEPIN 1,1-DIOKSIDA, PROSES PENYIAPAN, SEDIAAN FARMASI YANG MENGANDUNG SENYAWA-SENYAWA INI, DAN PENGGUNAANNYA
IDW20002564A ID26876A (id) 1998-06-10 1999-05-29 Derivat-derivat benzotiepin 1,1-dioksida, proses pembuatannya, bahan-bahan farmasi yang terdiri dari senyawa-senyawa ini dan penggunaannya

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IDW20002562A ID28695A (id) 1998-06-10 1999-05-28 TURUNAN-TURUNAN BENZO (b) TIEPIN 1,1-DIOKSIDA, PROSES PENYIAPAN, SEDIAAN FARMASI YANG MENGANDUNG SENYAWA-SENYAWA INI, DAN PENGGUNAANNYA

Country Status (25)

Country Link
US (1) US6387944B1 (id)
EP (2) EP1086092B1 (id)
JP (2) JP4374426B2 (id)
KR (2) KR100681721B1 (id)
CN (2) CN1127497C (id)
AR (2) AR018633A1 (id)
AT (2) ATE227715T1 (id)
AU (2) AU753275B2 (id)
BR (2) BR9912188B1 (id)
CA (2) CA2334775C (id)
CZ (2) CZ297989B6 (id)
DE (3) DE19825804C2 (id)
DK (2) DK1086092T3 (id)
ES (2) ES2182535T3 (id)
HU (2) HU229761B1 (id)
ID (2) ID28695A (id)
IL (1) IL140078A (id)
NO (1) NO327075B1 (id)
NZ (1) NZ508681A (id)
PL (2) PL196074B1 (id)
PT (2) PT1086092E (id)
RU (2) RU2215001C2 (id)
TR (2) TR200003634T2 (id)
WO (2) WO1999064410A1 (id)
ZA (2) ZA200007061B (id)

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US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
AU3103800A (en) 1998-12-23 2000-07-31 G.D. Searle Llc Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acidderivatives for cardiovascular indications
SE0000772D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab Chemical compounds
IL156550A0 (en) * 2000-12-21 2004-01-04 Aventis Pharma Gmbh Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism
DE10064402A1 (de) * 2000-12-21 2002-06-27 Aventis Pharma Gmbh Diphenylazetidinonderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EG26979A (en) 2000-12-21 2015-03-01 Astrazeneca Ab Chemical compounds
WO2003018024A1 (de) * 2001-08-22 2003-03-06 Aventis Pharma Deutschland Gmbh Kombinationspräparate von 1,4- benzothiepin-1,1-dioxidderivaten mit weiteren wirkstoffen und deren verwendung
GB0121337D0 (en) 2001-09-04 2001-10-24 Astrazeneca Ab Chemical compounds
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GB0209467D0 (en) 2002-04-25 2002-06-05 Astrazeneca Ab Chemical compounds
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SE0201937D0 (sv) 2002-06-20 2002-06-20 Astrazeneca Ab Therapeutic agents
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DE102006053635B4 (de) * 2006-11-14 2011-06-30 Sanofi-Aventis Deutschland GmbH, 65929 Neue mit Benzylresten substituierte 1,4-Benzothiepin-1,1-Dioxidderivate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
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Family Cites Families (5)

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ES2155136T3 (es) * 1994-09-13 2001-05-01 Monsanto Co Nuevas benzotiepinas que tienen actividad como inhibidores del transporte de acido biliar iliaco y la captacion de taurocolato.
US5994391A (en) * 1994-09-13 1999-11-30 G.D. Searle And Company Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
DE04010088T1 (de) * 1996-03-11 2005-07-14 G.D. Searle Llc Neue Benzothiepine mit pharmazeutischer Wirkung.
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
EP1104416A2 (en) * 1998-08-20 2001-06-06 Takeda Chemical Industries, Ltd. Quaternary ammonium salts and their use as anti-hiv agents

Also Published As

Publication number Publication date
ATE227715T1 (de) 2002-11-15
BR9912188B1 (pt) 2010-12-14
EP1086092A1 (de) 2001-03-28
HU228570B1 (en) 2013-04-29
KR100681721B1 (ko) 2007-02-15
CN1127497C (zh) 2003-11-12
NO327075B1 (no) 2009-04-20
ATE259372T1 (de) 2004-02-15
AU753275B2 (en) 2002-10-10
JP2002517490A (ja) 2002-06-18
DK1086113T3 (da) 2004-05-24
TR200003634T2 (tr) 2001-06-21
BR9911123A (pt) 2006-01-03
AR018634A1 (es) 2001-11-28
DK1086092T3 (da) 2003-03-10
RU2215001C2 (ru) 2003-10-27
CZ297989B6 (cs) 2007-05-16
EP1086092B1 (de) 2002-11-13
NO20006251L (no) 2001-02-07
PL344827A1 (en) 2001-11-19
JP2002517491A (ja) 2002-06-18
PL196074B1 (pl) 2007-12-31
KR100562184B1 (ko) 2006-03-20
PL345901A1 (en) 2002-01-14
AU4503199A (en) 1999-12-30
DE59908522D1 (de) 2004-03-18
CZ20004592A3 (cs) 2001-04-11
HUP0102554A1 (hu) 2001-10-28
CN1152039C (zh) 2004-06-02
WO1999064409A2 (de) 1999-12-16
WO1999064410A1 (de) 1999-12-16
HK1039490A1 (en) 2002-04-26
ZA200007060B (en) 2001-07-18
DE19825804C2 (de) 2000-08-24
HUP0102256A1 (hu) 2001-12-28
AU4501999A (en) 1999-12-30
KR20010052682A (ko) 2001-06-25
IL140078A (en) 2004-08-31
HK1036799A1 (en) 2002-01-18
BR9912188A (pt) 2001-04-10
AR018633A1 (es) 2001-11-28
NO20006251D0 (no) 2000-12-08
DE59903411D1 (de) 2002-12-19
JP3374129B2 (ja) 2003-02-04
ES2215387T3 (es) 2004-10-01
HUP0102256A3 (en) 2002-04-29
AU752633B2 (en) 2002-09-26
CA2334775A1 (en) 1999-12-16
ES2182535T3 (es) 2003-03-01
RU2220141C2 (ru) 2003-12-27
DE19825804A1 (de) 1999-12-16
ID28695A (id) 2001-06-28
HUP0102554A3 (en) 2002-12-28
EP1086113A2 (de) 2001-03-28
PT1086113E (pt) 2004-06-30
IL140078A0 (en) 2002-02-10
CA2334773C (en) 2009-05-26
NZ508681A (en) 2002-06-28
CN1305469A (zh) 2001-07-25
EP1086113B1 (de) 2004-02-11
ZA200007061B (en) 2001-07-18
HU229761B1 (hu) 2014-06-30
CA2334775C (en) 2009-10-13
CZ297925B6 (cs) 2007-05-02
JP4374426B2 (ja) 2009-12-02
US6387944B1 (en) 2002-05-14
TR200003632T2 (tr) 2001-04-20
KR20010052701A (ko) 2001-06-25
CA2334773A1 (en) 1999-12-16
WO1999064409A3 (de) 2000-03-02
CZ20004591A3 (cs) 2001-04-11
PT1086092E (pt) 2003-03-31
BR9911123B1 (pt) 2010-12-14
PL196057B1 (pl) 2007-11-30
CN1305487A (zh) 2001-07-25

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