ID27253A - Penggunaan turunan-turunan kampotesin dengan toksisitas gastrointestinal yang tereduksi - Google Patents

Penggunaan turunan-turunan kampotesin dengan toksisitas gastrointestinal yang tereduksi

Info

Publication number: ID27253A
Authority: ID; Indonesia
Prior art keywords: campotesin; decreases; gastrointestinal toxicity; reduced gastrointestinal; sodium chloride
Prior art date: 1998-08-05

Application number

IDW20010273A

Other languages

English (en)

Indonesian (id)

Inventor

Toutain Herve

Guffroy Magali

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-05

Filing date

1999-08-03

Publication date

2001-03-22

1998-08-05 Priority claimed from FR9810043A external-priority patent/FR2782009B1/fr

1999-08-03 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2001-03-22 Publication of ID27253A publication Critical patent/ID27253A/id

Links

206010059024 Gastrointestinal toxicity Diseases 0.000 title 1
231100000414 gastrointestinal toxicity Toxicity 0.000 title 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
239000011780 sodium chloride Substances 0.000 abstract 2
VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Inorganic Chemistry (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oil, Petroleum & Natural Gas (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Toxicology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Plant Substances (AREA)

IDW20010273A 1998-08-05 1999-08-03 Penggunaan turunan-turunan kampotesin dengan toksisitas gastrointestinal yang tereduksi ID27253A (id)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9810043A FR2782009B1 (fr)	1998-08-05	1998-08-05	Utilisation de derives de la comptothecine, avec une toxicite gastro-intestinale reduite
US9631898P	1998-08-12	1998-08-12

Publications (1)

Publication Number	Publication Date
ID27253A true ID27253A (id)	2001-03-22

Family

ID=26234482

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20010273A ID27253A (id)	1998-08-05	1999-08-03	Penggunaan turunan-turunan kampotesin dengan toksisitas gastrointestinal yang tereduksi

Country Status (24)

Country	Link
US (1)	US6476043B1 (de)
EP (1)	EP1102594B1 (de)
JP (1)	JP2002522392A (de)
KR (1)	KR20010072228A (de)
AT (1)	ATE217531T1 (de)
AU (1)	AU771195B2 (de)
BG (1)	BG64641B1 (de)
CA (1)	CA2340020A1 (de)
CZ (1)	CZ295775B6 (de)
DE (1)	DE69901506T2 (de)
DK (1)	DK1102594T3 (de)
EA (1)	EA002917B1 (de)
EE (1)	EE04264B1 (de)
ES (1)	ES2176009T3 (de)
GE (1)	GEP20043254B (de)
HU (1)	HUP0103314A3 (de)
ID (1)	ID27253A (de)
IL (1)	IL141232A0 (de)
NO (1)	NO20010454L (de)
NZ (1)	NZ509859A (de)
PT (1)	PT1102594E (de)
SK (1)	SK1732001A3 (de)
TR (1)	TR200100331T2 (de)
WO (1)	WO2000007605A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1749540B1 (de)	1999-05-17	2010-10-13	Cancer Research Ventures Limited	Zubereitungen zur Erhöhung der Bioverfügbarkeit von oral verabreichten pharmazeutischen Verbindungen
CA2295429A1 (en) *	2000-01-06	2001-07-06	Michael Michael	Treatment or prevention of diarrhea
US20080242691A1 (en) *	2004-02-13	2008-10-02	Kabushiki Kaisha Yakult Honsha	Aqueous Solution Preparation Containing Camptothecins
US20050197355A1 (en) *	2004-03-02	2005-09-08	Henegar Kevin E.	Compounds useful in preparing camptothecin derivatives
AU2005244768B2 (en)	2004-04-27	2011-06-09	Wellstat Biologics Corporation	Cancer treatment using viruses and camptothecins
JP2006151950A (ja) *	2004-11-05	2006-06-15	Oto Corporation:Kk	納豆菌培養エキス含有製剤及び納豆菌培養エキスの保存方法
DE602006009901D1 (de) *	2005-02-07	2009-12-03	Fermion Oy	Verfahren zur herstellung von 7-ethyl-10-hydroxycamptothecin
CA2591074C (en) *	2005-02-08	2015-01-20	Fermion Oy	Preparation method
CA2591071C (en) *	2005-02-08	2014-04-29	Fermion Oy	Process for producing [1,4'] bipiperidinyl-1'-carbonyl chloride or hydrochloride thereof
US7994186B2 (en) *	2005-04-18	2011-08-09	Kabushiki Kaisha Yakult Honsha	Pharmaceutical compositions containing camptothecins
AU2006270297B2 (en)	2005-07-14	2013-01-17	Wellstat Biologics Corporation	Cancer treatment using viruses, fluoropyrimidines and camptothecins

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4284579A (en) *	1979-07-17	1981-08-18	The United States Of America As Represented By The Of The Department Of Health & Human Services	(N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
US4399276A (en) *	1981-01-09	1983-08-16	Kabushiki Kaisha Yakult Honsha	7-Substituted camptothecin derivatives
JPS58154582A (ja) *	1982-03-10	1983-09-14	Yakult Honsha Co Ltd	新規なカンプトテシン誘導体およびその製造法
JPS6019790A (ja) *	1983-07-14	1985-01-31	Yakult Honsha Co Ltd	新規なカンプトテシン誘導体
CH663353A5 (de) *	1984-03-28	1987-12-15	Joaquin Amat Larraz	Mittel gegen krebs.
CA1332413C (en) *	1987-06-25	1994-10-11	Kabushiki Kaisha Yakult Honsha	Camptothecin derivatives and process for preparing same
US5004758A (en) *	1987-12-01	1991-04-02	Smithkline Beecham Corporation	Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells
US5225404A (en)	1989-11-06	1993-07-06	New York University	Methods of treating colon tumors with tumor-inhibiting camptothecin compounds
IT1247937B (it) *	1991-05-16	1995-01-05	Ist Naz Ric Sul Cancro	Associazione farmaceutica ad attivita' antineoplastica
JP3359955B2 (ja) *	1992-07-16	2002-12-24	第一製薬株式会社	抗腫瘍剤
WO1996011005A2 (en)	1994-10-06	1996-04-18	Atlas Leon T	Use of camptothecin or derivatives thereof for the manufacture of a medicament for the treatment of viral diseases

1999
- 1999-08-03 DK DK99936674T patent/DK1102594T3/da active
- 1999-08-03 EA EA200100214A patent/EA002917B1/ru unknown
- 1999-08-03 SK SK173-2001A patent/SK1732001A3/sk unknown
- 1999-08-03 GE GEAP19995779A patent/GEP20043254B/en unknown
- 1999-08-03 JP JP2000563290A patent/JP2002522392A/ja active Pending
- 1999-08-03 HU HU0103314A patent/HUP0103314A3/hu unknown
- 1999-08-03 KR KR1020017001471A patent/KR20010072228A/ko not_active Ceased
- 1999-08-03 TR TR2001/00331T patent/TR200100331T2/xx unknown
- 1999-08-03 ES ES99936674T patent/ES2176009T3/es not_active Expired - Lifetime
- 1999-08-03 US US09/762,092 patent/US6476043B1/en not_active Expired - Fee Related
- 1999-08-03 CZ CZ2001382A patent/CZ295775B6/cs not_active IP Right Cessation
- 1999-08-03 AT AT99936674T patent/ATE217531T1/de not_active IP Right Cessation
- 1999-08-03 WO PCT/FR1999/001916 patent/WO2000007605A1/fr not_active Ceased
- 1999-08-03 PT PT99936674T patent/PT1102594E/pt unknown
- 1999-08-03 EP EP99936674A patent/EP1102594B1/de not_active Expired - Lifetime
- 1999-08-03 NZ NZ509859A patent/NZ509859A/en unknown
- 1999-08-03 ID IDW20010273A patent/ID27253A/id unknown
- 1999-08-03 CA CA002340020A patent/CA2340020A1/fr not_active Abandoned
- 1999-08-03 DE DE69901506T patent/DE69901506T2/de not_active Expired - Fee Related
- 1999-08-03 AU AU51687/99A patent/AU771195B2/en not_active Ceased
- 1999-08-03 EE EEP200100066A patent/EE04264B1/xx not_active IP Right Cessation
- 1999-08-03 IL IL14123299A patent/IL141232A0/xx unknown
2001
- 2001-01-26 NO NO20010454A patent/NO20010454L/no not_active Application Discontinuation
- 2001-02-05 BG BG105216A patent/BG64641B1/bg unknown

Also Published As

Publication number	Publication date
WO2000007605A1 (fr)	2000-02-17
CA2340020A1 (fr)	2000-02-17
HUP0103314A2 (hu)	2002-01-28
HUP0103314A3 (en)	2002-07-29
DE69901506T2 (de)	2002-11-28
EP1102594B1 (de)	2002-05-15
DE69901506D1 (de)	2002-06-20
DK1102594T3 (da)	2002-08-26
BG105216A (en)	2001-10-31
NZ509859A (en)	2003-09-26
SK1732001A3 (en)	2001-06-11
EE04264B1 (et)	2004-04-15
CZ2001382A3 (en)	2001-05-16
NO20010454D0 (no)	2001-01-26
JP2002522392A (ja)	2002-07-23
KR20010072228A (ko)	2001-07-31
ES2176009T3 (es)	2002-11-16
GEP20043254B (en)	2004-06-25
EA200100214A1 (ru)	2001-08-27
NO20010454L (no)	2001-01-26
TR200100331T2 (tr)	2001-07-23
ATE217531T1 (de)	2002-06-15
BG64641B1 (bg)	2005-10-31
EP1102594A1 (de)	2001-05-30
EE200100066A (et)	2002-06-17
PT1102594E (pt)	2002-10-31
AU771195B2 (en)	2004-03-18
CZ295775B6 (cs)	2005-11-16
EA002917B1 (ru)	2002-10-31
US6476043B1 (en)	2002-11-05
IL141232A0 (en)	2002-03-10
AU5168799A (en)	2000-02-28

Publication	Publication Date	Title
TR199800436A2 (xx)	1998-10-21	Primidin t�revlerinin kanserin �nlenmesi i�in kullan�lmas�.
DK0774963T3 (da)	2001-01-29	Farmaceutisk stabilt oxaliplatin-præparat
TR200102603T2 (tr)	2002-01-21	Antitümör aktiviteye sahip olan kamptotesin türevleri
EP1541151A4 (de)	2007-07-18	MITTEL ZUR BEHANDLUNG VON GLAUKOM MIT EINEM Rho-KINASE-HEMMER UND PROSTAGLANDINEN
MY121517A (en)	2006-01-28	Anticonvulsant derivatives useful in reducing blood glucose levels
ID27253A (id)	2001-03-22	Penggunaan turunan-turunan kampotesin dengan toksisitas gastrointestinal yang tereduksi
TR200101719T2 (tr)	2002-08-21	Erkeklerde organik ereksiyona bağlı işlev bozukluğunun tedavisi için ilaç imalatında apomorfin kullanımı
DK1157030T3 (da)	2003-12-22	Enchinocanidin/carbohydratkomplekser
BRPI0409959A (pt)	2006-04-25	uso de derivados de azetidinacarboxamida em terapia
DK1377164T3 (da)	2008-10-13	Erythropoietin forbedrer kemoterapi-induceret toksicitet in vivo
BG106602A (en)	2002-12-29	Formulation of substituted benzimidazoles
TR200102008T2 (tr)	2001-12-21	Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı.
PL360492A1 (en)	2004-09-06	Use of pamoic acid or one of its derivatives, or one of its analogues, for the preparation of a medicament for the treatment of diseases characterised by deposits of amyloid aggregates
AU2162202A (en)	2002-04-15	Antitumor therapy comprising distamycin derivatives
PT1280527E (pt)	2005-10-31	Utilizacao de derivados de acriloil distamicina no tratamento de tumores associados a niveis de glutationa elevados
EE200200660A (et)	2004-06-15	Akrüloüüldistamütsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritudravimpreparaat
TR200102262T2 (tr)	2002-02-21	Koroner müdahale ile ilgili kardiovasküler olayların önlenmesi veya azaltılması için yöntem.
YU5301A (sh)	2005-06-10	Primena derivata kamptotecina sa smanjenom gastro-intestinalnom toksičnošću
FR2308368A1 (fr)	1976-11-19	Sel soluble de la cephalexine comme antibiotique injectable
IT1314204B1 (it)	2002-12-06	Complessi di rutenio con elevata attivita' antitumorale