IL111925A - Preparation of agents containing virus-inactivated vitamin K-dependent plasma components protein C and protein S by membrane chromatography - Google Patents

Preparation of agents containing virus-inactivated vitamin K-dependent plasma components protein C and protein S by membrane chromatography

Info

Publication number
IL111925A
IL111925A IL11192594A IL11192594A IL111925A IL 111925 A IL111925 A IL 111925A IL 11192594 A IL11192594 A IL 11192594A IL 11192594 A IL11192594 A IL 11192594A IL 111925 A IL111925 A IL 111925A
Authority
IL
Israel
Prior art keywords
protein
preparation
agents containing
plasma components
containing virus
Prior art date
Application number
IL11192594A
Other languages
English (en)
Other versions
IL111925A0 (en
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of IL111925A0 publication Critical patent/IL111925A0/xx
Publication of IL111925A publication Critical patent/IL111925A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11192594A 1993-12-10 1994-12-07 Preparation of agents containing virus-inactivated vitamin K-dependent plasma components protein C and protein S by membrane chromatography IL111925A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4342132A DE4342132C1 (de) 1993-12-10 1993-12-10 Verfahren zur Herstellung virusinaktivierte Vitamin K abhängige Plasmakomponenten sowie Protein C und Protein S enthaltender Mittel durch Membran-Chromatographie

Publications (2)

Publication Number Publication Date
IL111925A0 IL111925A0 (en) 1995-03-15
IL111925A true IL111925A (en) 2000-06-01

Family

ID=6504650

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11192594A IL111925A (en) 1993-12-10 1994-12-07 Preparation of agents containing virus-inactivated vitamin K-dependent plasma components protein C and protein S by membrane chromatography

Country Status (19)

Country Link
US (2) US20020045240A1 (de)
EP (1) EP0733104B1 (de)
JP (1) JPH09506256A (de)
KR (1) KR100320394B1 (de)
CN (1) CN1175105C (de)
AT (1) ATE276357T1 (de)
AU (1) AU682560B2 (de)
CA (1) CA2178208C (de)
CZ (1) CZ291708B6 (de)
DE (2) DE4342132C1 (de)
DK (1) DK0733104T3 (de)
ES (1) ES2224119T3 (de)
HU (1) HU222084B1 (de)
IL (1) IL111925A (de)
PL (1) PL180179B1 (de)
PT (1) PT733104E (de)
UA (1) UA44261C2 (de)
WO (1) WO1995016030A1 (de)
ZA (1) ZA949820B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT409334B (de) * 1997-09-19 2002-07-25 Immuno Ag Pharmazeutisches präparat enthaltend vitamin k-abhängige einzelfaktoren
EP1691820A4 (de) 2003-11-08 2010-03-03 Prothera Biolog Herstellung und zusammensetzung von inter-alpha-hemmer-proteinen aus menschlichem plasma für die therapeutische anwendung
JP2005315666A (ja) * 2004-04-28 2005-11-10 Toshihiko Hanai 糖結合充填剤およびその製造方法
EP2360171A1 (de) 2004-12-23 2011-08-24 Novo Nordisk Health Care AG Reduktion des Gehaltes an kontaminierenden Proteinen in Zusammensetzungen, die Vitamin K-abhängige Proteine von Interesse umfassen
KR100667860B1 (ko) * 2005-10-18 2007-01-11 주식회사 녹십자 고순도 사람 혈액응고 제9인자의 정제 방법
SG185005A1 (en) * 2010-04-29 2012-11-29 Baxter Int Purification method for divalent cation binding proteins on anion exchange resin
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
CN103665098B (zh) * 2012-09-20 2015-08-05 中国科学院大连化学物理研究所 双相柱膜蛋白质微反应器及其应用
CN104447975A (zh) * 2014-11-18 2015-03-25 深圳市人口和计划生育科学研究所 一种提取人肿瘤细胞膜蛋白的方法
ES2991988T3 (es) 2017-10-30 2024-12-05 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivación de virus con envoltura lipídica
CN111378029B (zh) * 2018-12-29 2023-05-05 四川远大蜀阳药业有限责任公司 一种人凝血因子ix的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3173208D1 (en) * 1980-10-06 1986-01-23 Edward Shanbrom Method of reducing undesirable activities of biological and pharmaceutical products
DE3045153A1 (de) * 1980-11-29 1982-07-08 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von blutgerinnungsfaktoren und danach hergestellte praeparation der faktoren ix und x
US4820805A (en) * 1983-07-14 1989-04-11 New York Blood Center, Inc. Undenatured virus-free trialkyl phosphate treated biologically active protein derivatives
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
ATE130620T1 (de) * 1986-01-06 1995-12-15 Blood Systems Inc Therapeutisches blutprodukt, mittel und verfahren zu dessen erzeugung.
EP0317376B2 (de) * 1987-10-23 1996-04-03 Centre Regional De Transfusion Sanguine De Lille Herstellung von hoch-gereingtem menschlichen Faktor IX sowie anderem Plasmaproteinkonzentrat
CA2001720C (en) * 1988-10-31 2001-10-02 Randal A. Goffe Membrane affinity apparatus and purification methods related thereto
DE3914869C1 (de) * 1989-05-05 1990-08-09 Biotest Pharma Gmbh, 6072 Dreieich, De
EP0513332A4 (en) * 1990-11-14 1993-03-17 Cargill, Incorporated Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
AT402261B (de) * 1991-01-25 1997-03-25 Immuno Ag Komplex enthaltend den gerinnungsfaktor ix
AT402891B (de) * 1991-06-20 1997-09-25 Immuno Ag Verfahren zur herstellung eines inaktivierten blutproduktes
DE4204694C3 (de) * 1992-02-01 1995-10-12 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem Faktor VIII mittels Anionenaustauscher-Chromatographie

Also Published As

Publication number Publication date
US20020182582A1 (en) 2002-12-05
US6893856B2 (en) 2005-05-17
PL180179B1 (pl) 2000-12-29
AU682560B2 (en) 1997-10-09
WO1995016030A1 (en) 1995-06-15
EP0733104B1 (de) 2004-09-15
HU222084B1 (hu) 2003-04-28
HUT76881A (en) 1997-12-29
ZA949820B (en) 1995-08-16
IL111925A0 (en) 1995-03-15
CN1137292A (zh) 1996-12-04
CZ291708B6 (cs) 2003-05-14
PT733104E (pt) 2004-12-31
CN1175105C (zh) 2004-11-10
ES2224119T3 (es) 2005-03-01
JPH09506256A (ja) 1997-06-24
CA2178208A1 (en) 1995-06-15
ATE276357T1 (de) 2004-10-15
AU1242595A (en) 1995-06-27
DE69434001T2 (de) 2005-09-22
HU9601594D0 (en) 1996-07-29
CZ167096A3 (en) 1996-09-11
UA44261C2 (uk) 2002-02-15
US20020045240A1 (en) 2002-04-18
PL314801A1 (en) 1996-09-30
DK0733104T3 (da) 2005-01-17
DE4342132C1 (de) 1994-11-03
EP0733104A1 (de) 1996-09-25
DE69434001D1 (de) 2004-10-21
CA2178208C (en) 2009-06-02
KR100320394B1 (ko) 2002-07-31

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Legal Events

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FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees