IL120584A - 1,2-diphenylpyrrole derivatives, use thereof for the manufacture of a medicament and pharmaceutical compositions containing the same - Google Patents

1,2-diphenylpyrrole derivatives, use thereof for the manufacture of a medicament and pharmaceutical compositions containing the same

Info

Publication number: IL120584A
Authority: IL; Israel
Prior art keywords: medicament; alkyl; manufacture; same; hydrogen
Prior art date: 1996-04-05

Application number

IL12058497A

Other languages

English (en)

Other versions

IL120584A0 (en

Original Assignee

Sankyo Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-05

Filing date

1997-04-01

Publication date

2003-10-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13805966&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL120584(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-04-01 Application filed by Sankyo Co filed Critical Sankyo Co

1997-08-14 Publication of IL120584A0 publication Critical patent/IL120584A0/xx

2003-10-31 Publication of IL120584A publication Critical patent/IL120584A/xx

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
ZZDIPNSMKJPHTR-UHFFFAOYSA-N 1,2-diphenylpyrrole Chemical class C=1C=CC=CC=1N1C=CC=C1C1=CC=CC=C1 ZZDIPNSMKJPHTR-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
150000002431 hydrogen Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000000547 substituted alkyl group Chemical group 0.000 abstract 2
208000006386 Bone Resorption Diseases 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
230000003266 anti-allergic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000001754 anti-pyretic effect Effects 0.000 abstract 1
239000002221 antipyretic Substances 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
230000024279 bone resorption Effects 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
150000002617 leukotrienes Chemical class 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Hematology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Ophthalmology & Optometry (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)

IL12058497A 1996-04-05 1997-04-01 1,2-diphenylpyrrole derivatives, use thereof for the manufacture of a medicament and pharmaceutical compositions containing the same IL120584A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP8356296		1996-04-05

Publications (2)

Publication Number	Publication Date
IL120584A0 IL120584A0 (en)	1997-08-14
IL120584A true IL120584A (en)	2003-10-31

Family

ID=13805966

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12058497A IL120584A (en)	1996-04-05	1997-04-01	1,2-diphenylpyrrole derivatives, use thereof for the manufacture of a medicament and pharmaceutical compositions containing the same

Country Status (20)

Country	Link
US (2)	US5908858A (de)
EP (1)	EP0799823B1 (de)
JP (1)	JP3034819B2 (de)
KR (1)	KR100485426B1 (de)
CN (1)	CN1151126C (de)
AT (1)	ATE376998T1 (de)
CA (1)	CA2201812C (de)
CZ (1)	CZ293048B6 (de)
DE (1)	DE69738245T2 (de)
DK (1)	DK0799823T3 (de)
ES (1)	ES2296303T3 (de)
HU (1)	HU227830B1 (de)
ID (1)	ID17358A (de)
IL (1)	IL120584A (de)
NO (1)	NO308736B1 (de)
NZ (1)	NZ314508A (de)
PT (1)	PT799823E (de)
RU (1)	RU2125044C1 (de)
TW (1)	TW409122B (de)
ZA (1)	ZA972846B (de)

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1997
- 1997-03-26 US US08/824,775 patent/US5908858A/en not_active Ceased
- 1997-04-01 IL IL12058497A patent/IL120584A/xx not_active IP Right Cessation
- 1997-04-02 NZ NZ314508A patent/NZ314508A/xx not_active IP Right Cessation
- 1997-04-02 PT PT97302245T patent/PT799823E/pt unknown
- 1997-04-02 DE DE69738245T patent/DE69738245T2/de not_active Expired - Lifetime
- 1997-04-02 ES ES97302245T patent/ES2296303T3/es not_active Expired - Lifetime
- 1997-04-02 AT AT97302245T patent/ATE376998T1/de active
- 1997-04-02 DK DK97302245T patent/DK0799823T3/da active
- 1997-04-02 EP EP97302245A patent/EP0799823B1/de not_active Expired - Lifetime
- 1997-04-03 ZA ZA9702846A patent/ZA972846B/xx unknown
- 1997-04-03 TW TW086104297A patent/TW409122B/zh not_active IP Right Cessation
- 1997-04-03 KR KR1019970012430A patent/KR100485426B1/ko not_active Expired - Fee Related
- 1997-04-04 JP JP9086889A patent/JP3034819B2/ja not_active Expired - Fee Related
- 1997-04-04 ID IDP971140A patent/ID17358A/id unknown
- 1997-04-04 CA CA002201812A patent/CA2201812C/en not_active Expired - Fee Related
- 1997-04-04 RU RU97105191A patent/RU2125044C1/ru not_active IP Right Cessation
- 1997-04-04 CZ CZ19971035A patent/CZ293048B6/cs not_active IP Right Cessation
- 1997-04-04 HU HU9700709A patent/HU227830B1/hu not_active IP Right Cessation
- 1997-04-04 NO NO971564A patent/NO308736B1/no not_active IP Right Cessation
- 1997-04-05 CN CNB971134049A patent/CN1151126C/zh not_active Expired - Fee Related
2000
- 2000-09-29 US US09/678,218 patent/USRE39420E1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ID17358A (id)	1997-12-24
AU1665397A (en)	1997-10-09
CZ293048B6 (cs)	2004-01-14
NZ314508A (en)	1999-06-29
US5908858A (en)	1999-06-01
HUP9700709A3 (en)	2000-04-28
CN1168372A (zh)	1997-12-24
EP0799823A1 (de)	1997-10-08
CA2201812C (en)	2007-09-18
ZA972846B (en)	1997-11-04
JP3034819B2 (ja)	2000-04-17
HUP9700709A2 (hu)	1999-05-28
RU2125044C1 (ru)	1999-01-20
CN1151126C (zh)	2004-05-26
CZ103597A3 (en)	1997-10-15
DE69738245T2 (de)	2008-08-14
ES2296303T3 (es)	2008-04-16
DE69738245D1 (de)	2007-12-13
TW409122B (en)	2000-10-21
IL120584A0 (en)	1997-08-14
NO971564L (no)	1997-10-06
NO971564D0 (no)	1997-04-04
KR100485426B1 (ko)	2005-10-12
USRE39420E1 (en)	2006-12-05
DK0799823T3 (da)	2008-03-03
JPH09323971A (ja)	1997-12-16
HU227830B1 (hu)	2012-05-02
EP0799823B1 (de)	2007-10-31
HK1003268A1 (en)	1998-10-23
HU9700709D0 (en)	1997-05-28
PT799823E (pt)	2008-01-15
ATE376998T1 (de)	2007-11-15
NO308736B1 (no)	2000-10-23
CA2201812A1 (en)	1997-10-05
AU710380B2 (en)	1999-09-16
KR970069985A (ko)	1997-11-07

Legal Events

Date	Code	Title
2004-03-28	FF	Patent granted
2004-06-20	KB	Patent renewed
2007-07-24	KB	Patent renewed
2011-04-28	KB	Patent renewed
2015-11-30	MM9K	Patent not in force due to non-payment of renewal fees

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