ID17358A - Turunan-turunan 1,2-difenilpirol, pembuatan dan penggunaan-penggunaan terapinya - Google Patents
Turunan-turunan 1,2-difenilpirol, pembuatan dan penggunaan-penggunaan terapinyaInfo
- Publication number
- ID17358A ID17358A IDP971140A ID971140A ID17358A ID 17358 A ID17358 A ID 17358A ID P971140 A IDP971140 A ID P971140A ID 971140 A ID971140 A ID 971140A ID 17358 A ID17358 A ID 17358A
- Authority
- ID
- Indonesia
- Prior art keywords
- alkyl
- hydrogen
- optionally substituted
- difenilpirol
- declinations
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 208000006386 Bone Resorption Diseases 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000024279 bone resorption Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002617 leukotrienes Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8356296 | 1996-04-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID17358A true ID17358A (id) | 1997-12-24 |
Family
ID=13805966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDP971140A ID17358A (id) | 1996-04-05 | 1997-04-04 | Turunan-turunan 1,2-difenilpirol, pembuatan dan penggunaan-penggunaan terapinya |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US5908858A (de) |
| EP (1) | EP0799823B1 (de) |
| JP (1) | JP3034819B2 (de) |
| KR (1) | KR100485426B1 (de) |
| CN (1) | CN1151126C (de) |
| AT (1) | ATE376998T1 (de) |
| CA (1) | CA2201812C (de) |
| CZ (1) | CZ293048B6 (de) |
| DE (1) | DE69738245T2 (de) |
| DK (1) | DK0799823T3 (de) |
| ES (1) | ES2296303T3 (de) |
| HU (1) | HU227830B1 (de) |
| ID (1) | ID17358A (de) |
| IL (1) | IL120584A (de) |
| NO (1) | NO308736B1 (de) |
| NZ (1) | NZ314508A (de) |
| PT (1) | PT799823E (de) |
| RU (1) | RU2125044C1 (de) |
| TW (1) | TW409122B (de) |
| ZA (1) | ZA972846B (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09212974A (ja) * | 1996-01-31 | 1997-08-15 | Mitsubishi Electric Corp | ディスク装置 |
| CN1255396C (zh) * | 1996-03-18 | 2006-05-10 | 卫材株式会社 | 含有稠环的羧酸衍生物 |
| ATE233743T1 (de) * | 1996-04-12 | 2003-03-15 | Searle & Co | N-((4-(5-methyl-3-phenylisoxazol-4- yl)phenyl)sulphonylpropylamid und sein natriumsalz als pro-pharmakon von cox-2 inhibitoren |
| PT946507E (pt) * | 1996-12-10 | 2004-02-27 | Searle & Co | Compostos de pirrolilo substituidos para o tratamento da inflamacao |
| EP1369415A1 (de) * | 1996-12-10 | 2003-12-10 | G.D. Searle & Co. | Pyrrole Derivate zur Behandlung von Entzündungen |
| NZ333399A (en) * | 1997-12-24 | 2000-05-26 | Sankyo Co | Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis |
| RU2220721C2 (ru) * | 1997-12-24 | 2004-01-10 | Санкио Компани, Лимитед | Активный агент для ингибирования роста опухолей у млекопитающих, лечения и/или профилактики связанных с опухолями нарушений и метастаз опухолей у млекопитающих |
| AU3953899A (en) * | 1998-05-27 | 1999-12-13 | Nippon Shinyaku Co. Ltd. | Cyclooxygenase-2 inhibitors |
| AU4395399A (en) * | 1998-07-02 | 2000-01-24 | Sankyo Company Limited | Five-membered heteroaryl compounds |
| RU2190399C2 (ru) * | 1998-07-21 | 2002-10-10 | Санкио Компани Лимитед | Средство для лечения и предотвращения кахексии |
| US6649645B1 (en) * | 1998-12-23 | 2003-11-18 | Pharmacia Corporation | Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia |
| US7122666B2 (en) | 1999-07-21 | 2006-10-17 | Sankyo Company, Limited | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses |
| WO2001030757A1 (en) * | 1999-10-28 | 2001-05-03 | Microcide Pharmaceuticals, Inc. | Drug discharge pump inhibitors |
| KR100793668B1 (ko) | 1999-12-08 | 2008-01-10 | 파마시아 코포레이션 | 강화된 생체이용률을 지닌 고체상 형태의 셀레콕시브 |
| US6376489B1 (en) * | 1999-12-23 | 2002-04-23 | Icos Corporation | Cyclic AMP-specific phosphodiesterase inhibitors |
| US6372777B1 (en) * | 1999-12-23 | 2002-04-16 | Icos Corporation | Cyclic AMP-specific phosphodiesterase inhibitors |
| AP2002002582A0 (en) | 1999-12-23 | 2002-09-30 | Nitromed Inc | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use |
| RU2198170C2 (ru) * | 1999-12-27 | 2003-02-10 | Санкио Компани, Лимитед | Производные пиррола, фармацевтические композиции на их основе и способ лечения |
| US6440994B1 (en) * | 2000-03-29 | 2002-08-27 | Richard J. Sanders, Jr. | Method of treating acne |
| PE20021017A1 (es) | 2001-04-03 | 2002-11-24 | Pharmacia Corp | Composicion parenteral reconstituible |
| WO2002080974A1 (en) * | 2001-04-04 | 2002-10-17 | Sankyo Company, Limited | Novel medicinal use of cytokine production inhibitor |
| US20030105144A1 (en) | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
| US6673818B2 (en) | 2001-04-20 | 2004-01-06 | Pharmacia Corporation | Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation |
| AR038957A1 (es) | 2001-08-15 | 2005-02-02 | Pharmacia Corp | Terapia de combinacion para el tratamiento del cancer |
| GB0212785D0 (en) * | 2002-05-31 | 2002-07-10 | Glaxo Group Ltd | Compounds |
| JP2005535642A (ja) * | 2002-06-28 | 2005-11-24 | ニトロメッド インコーポレーティッド | オキシムおよび/またはヒドラゾンを含有するニトロソ化および/またはニトロシル化シクロオキシゲナーゼ−2選択的阻害剤、組成物、および使用方法 |
| JP4458514B2 (ja) * | 2002-07-18 | 2010-04-28 | 第一三共株式会社 | 高純度のエナミン類の製造方法 |
| ATE555089T1 (de) * | 2002-08-20 | 2012-05-15 | Daiichi Sankyo Co Ltd | Verfahren zur herstellung von -ketoacetalen |
| JP4601274B2 (ja) * | 2002-08-20 | 2010-12-22 | 第一三共株式会社 | γ−ケトアセタール類の製造方法 |
| GB0225548D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Compounds |
| RU2308264C2 (ru) * | 2002-12-02 | 2007-10-20 | Каунсел Оф Сайнтифик Энд Индастриал Рисерч | Способ профилактики и/или лечения астмы с использованием рврв |
| AU2003303041B2 (en) | 2002-12-13 | 2008-07-24 | Warner-Lambert Company Llc | Alpha-2-delta ligand to treat lower urinary tract symptoms |
| ES2275218T3 (es) * | 2003-05-07 | 2007-06-01 | Osteologix A/S | Sales de estroncio hidrosolubles para el tratamiento de afecciones de cartilagos y/o huesos. |
| EP1622630B1 (de) * | 2003-05-07 | 2012-08-29 | Osteologix A/S | Strontium-kombinationsbehandlung zur prophylaxe/behandlung von knorpel- und knochenzuständen |
| GB0328024D0 (en) * | 2003-12-03 | 2004-01-07 | Glaxo Group Ltd | Compounds |
| BRPI0506994A (pt) | 2004-01-22 | 2007-07-03 | Pfizer | derivados de triazol que inibem a atividade antagonista da vasopressina |
| JP2009510090A (ja) * | 2005-09-27 | 2009-03-12 | ミリアド ジェネティックス インコーポレーティッド | 治療化合物としてのピロール誘導体 |
| US20070167510A1 (en) * | 2006-01-13 | 2007-07-19 | Suzanne Lentzsch | Methods for inhibiting osteoclastogenesis |
| EP2041085A1 (de) | 2006-06-27 | 2009-04-01 | Abbott Laboratories | Pyrrolderivate und ihre anwendungsverfahren |
| EP1889617A1 (de) * | 2006-07-11 | 2008-02-20 | Freie Universität Berlin | Triphenylsubstituierte fünfgliedrige Heterocyclen und deren Verwendung als Antikreb- und entzündungshemmende Mittel |
| EP2059504B1 (de) | 2006-08-03 | 2015-09-09 | Rottapharm Biotech S.r.l. | 3-substituierte 1,5-diaryl-2-alkylpyrrole als hochselektive und oral wirksame cox-2-inhibitoren |
| TW200812950A (en) * | 2006-08-18 | 2008-03-16 | Daiichi Sankyo Co Ltd | Process for producing acetophenone bromide |
| CA2662870A1 (en) * | 2006-09-07 | 2008-03-13 | Myriad Genetics, Inc. | Therapeutic compounds for diseases and disorders |
| CA2673545A1 (en) | 2006-12-22 | 2008-07-03 | Recordati Ireland Limited | Combination therapy of lower urinary tract disorders with .alpha.2.delta. ligands and nsaids |
| EP2114461A2 (de) * | 2007-01-19 | 2009-11-11 | Mallinckrodt Inc. | Diagnostische und therapeutische cyclooxygenase-2-bindende liganden |
| WO2009009776A2 (en) * | 2007-07-12 | 2009-01-15 | Tragara Pharmaceuticals, Inc. | Patient selection and therapeutic methods using markers of prostaglandin metabolism |
| MX2010000465A (es) * | 2007-07-12 | 2010-08-30 | Tragara Pharmaceuticals Inc | Metodos y composiciones para el tratamiento de cancer, tumores y alteraciones relacionadas con tumores. |
| WO2009042618A1 (en) * | 2007-09-24 | 2009-04-02 | Tragara Pharmaceuticals, Inc. | Therapies for treating cancer using combinations of cox-2 inhibitors and anti-her2(erbb2) antibodies or combinations of cox-2 inhibitors and her2(erbb2) receptor tyrosine kinase inhibitors |
| EP2284154A1 (de) * | 2009-07-29 | 2011-02-16 | Argon Pharma S.L. | Antitumorigene 1,2-Diphenylpyrrolverbindungen und deren Herstellungsverfahren |
| ES2372769B1 (es) * | 2010-07-08 | 2012-12-03 | Universitat De Barcelona | Fenil metil sulfonas con actividad antiiflamatoria y actividad antitumoral. |
| EP2691368A1 (de) * | 2011-03-31 | 2014-02-05 | Lupin Limited | Pyrrolderivate als modulatoren des nikotinischen acetylcholinrezeptors zur verwendung bei der behandlung von neurodegenerativen erkrankungen wie morbus alzheimer und morbus parkinson |
| EP3655513A1 (de) | 2017-07-18 | 2020-05-27 | Firmenich SA | Zyklamengeruchsstoff |
| IL305573A (en) | 2021-03-15 | 2023-10-01 | Saul Yedgar | HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES |
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|---|---|---|---|---|
| FR1356901A (fr) | 1958-03-13 | 1964-04-03 | Nouveaux aminoétheroxydes, aminothioéthers et aminoesters dérivés du pyrrole, etleur procédé de préparation | |
| US3168532A (en) | 1963-06-12 | 1965-02-02 | Parke Davis & Co | 1, 5-diarylpyrrole-2-propionic acid compounds |
| US3168531A (en) | 1963-06-12 | 1965-02-02 | Parke Davis & Co | 1-aryl-5-(p-lower alkoxyphenyl)-pyrrole-2-propionic acid compounds |
| US3285931A (en) | 1964-12-21 | 1966-11-15 | Union Carbide Corp | Preparation of substituted pyrrole derivatives |
| US3427305A (en) * | 1966-11-01 | 1969-02-11 | Searle & Co | 5 - ((halo/alkoxy)phenyl) - 1 - (p - sulfonamido(phenyl/benzyl)) - 2 - pyrrolepropionic acids |
| US3551571A (en) | 1967-05-19 | 1970-12-29 | Endo Lab | Methods for reducing pain,reducing fever and alleviating inflammatory syndromes with heteroaromatic pyrrol-3-yl ketones |
| GB1271082A (en) | 1968-05-07 | 1972-04-19 | Wyeth John & Brother Ltd | Furan, pyrrole and thiophene derivatives |
| GB1263940A (en) * | 1968-08-02 | 1972-02-16 | Innothera Lab Sa | 0-phenyl-pyrroles |
| FR2054474A2 (en) | 1969-07-09 | 1971-04-23 | Innothera Lab Sa | Analgesic, antiinflammatory 1-phenyl-2, 5-di |
| US3714232A (en) | 1969-06-25 | 1973-01-30 | Merck & Co Inc | 5-arylphenyl sulfonic acids |
| US4093735A (en) | 1974-04-25 | 1978-06-06 | Hoechst Aktiengesellschaft | 5-Sulfamoylbenzoic acid derivatives carrying a heterocyclic substituent |
| DE2419970C3 (de) | 1974-04-25 | 1980-06-12 | Hoechst Ag, 6000 Frankfurt | 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung |
| CH628622A5 (de) | 1976-12-24 | 1982-03-15 | Ciba Geigy Ag | Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren. |
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| DE3309355A1 (de) | 1983-03-16 | 1984-09-27 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von pyrrolen |
| US4694018A (en) * | 1985-11-29 | 1987-09-15 | G. D. Serale & Co. | Substituted 1,5-diphenyl-2-pyrrolepropionic acids and derivatives |
| US4792568A (en) | 1986-04-14 | 1988-12-20 | Rorer Pharmaceutical Corporation | Aryl pyrroles as useful antiallergy compounds |
| NO881411L (no) | 1987-04-14 | 1988-10-17 | Bayer Ag | Substituerte pyrroler. |
| US5310938A (en) * | 1987-07-29 | 1994-05-10 | American Cyanamid Company | Substituted arylpyrrole compounds |
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-
1997
- 1997-03-26 US US08/824,775 patent/US5908858A/en not_active Ceased
- 1997-04-01 IL IL12058497A patent/IL120584A/xx not_active IP Right Cessation
- 1997-04-02 NZ NZ314508A patent/NZ314508A/xx not_active IP Right Cessation
- 1997-04-02 PT PT97302245T patent/PT799823E/pt unknown
- 1997-04-02 DE DE69738245T patent/DE69738245T2/de not_active Expired - Lifetime
- 1997-04-02 ES ES97302245T patent/ES2296303T3/es not_active Expired - Lifetime
- 1997-04-02 AT AT97302245T patent/ATE376998T1/de active
- 1997-04-02 DK DK97302245T patent/DK0799823T3/da active
- 1997-04-02 EP EP97302245A patent/EP0799823B1/de not_active Expired - Lifetime
- 1997-04-03 ZA ZA9702846A patent/ZA972846B/xx unknown
- 1997-04-03 TW TW086104297A patent/TW409122B/zh not_active IP Right Cessation
- 1997-04-03 KR KR1019970012430A patent/KR100485426B1/ko not_active Expired - Fee Related
- 1997-04-04 JP JP9086889A patent/JP3034819B2/ja not_active Expired - Fee Related
- 1997-04-04 ID IDP971140A patent/ID17358A/id unknown
- 1997-04-04 CA CA002201812A patent/CA2201812C/en not_active Expired - Fee Related
- 1997-04-04 RU RU97105191A patent/RU2125044C1/ru not_active IP Right Cessation
- 1997-04-04 CZ CZ19971035A patent/CZ293048B6/cs not_active IP Right Cessation
- 1997-04-04 HU HU9700709A patent/HU227830B1/hu not_active IP Right Cessation
- 1997-04-04 NO NO971564A patent/NO308736B1/no not_active IP Right Cessation
- 1997-04-05 CN CNB971134049A patent/CN1151126C/zh not_active Expired - Fee Related
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2000
- 2000-09-29 US US09/678,218 patent/USRE39420E1/en not_active Expired - Lifetime
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