IL122609A0 - Meiosis regulating compounds - Google Patents

Meiosis regulating compounds

Info

Publication number
IL122609A0
IL122609A0 IL12260996A IL12260996A IL122609A0 IL 122609 A0 IL122609 A0 IL 122609A0 IL 12260996 A IL12260996 A IL 12260996A IL 12260996 A IL12260996 A IL 12260996A IL 122609 A0 IL122609 A0 IL 122609A0
Authority
IL
Israel
Prior art keywords
regulating compounds
meiosis regulating
meiosis
compounds
regulating
Prior art date
Application number
IL12260996A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL122609A0 publication Critical patent/IL122609A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL12260996A 1995-06-23 1996-06-21 Meiosis regulating compounds IL122609A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK72895 1995-06-23
DK73095 1995-06-23
DK146195 1995-12-22
PCT/DK1996/000273 WO1997000884A1 (en) 1995-06-23 1996-06-21 Meiosis regulating compounds

Publications (1)

Publication Number Publication Date
IL122609A0 true IL122609A0 (en) 1998-08-16

Family

ID=27220892

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12260996A IL122609A0 (en) 1995-06-23 1996-06-21 Meiosis regulating compounds

Country Status (18)

Country Link
EP (1) EP0857173B1 (de)
JP (1) JPH11507929A (de)
KR (1) KR19990028366A (de)
CN (1) CN1191543A (de)
AR (1) AR003441A1 (de)
AT (1) ATE254628T1 (de)
AU (1) AU718246B2 (de)
BR (1) BR9608968A (de)
CA (1) CA2224866A1 (de)
CZ (1) CZ408097A3 (de)
DE (1) DE69630802T2 (de)
HU (1) HUP9900454A3 (de)
IL (1) IL122609A0 (de)
NO (1) NO314231B1 (de)
PL (1) PL185622B1 (de)
RU (1) RU2182909C2 (de)
TW (1) TW474943B (de)
WO (1) WO1997000884A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU726016B2 (en) * 1997-05-16 2000-10-26 Akzo Nobel N.V. 20-aralkyl-5alpha-pregnane derivatives
IL132799A0 (en) * 1997-06-04 2001-03-19 Akzo Nobel Nv 17Beta-allyloxy(thio)alkyl-androstane derivatives for the modulation of meiosis
ATE220686T1 (de) 1997-12-18 2002-08-15 Akzo Nobel Nv 17beta-aryl(arylmethyl)oxy(thio)alkyl- androstanderivative
EP0957108A1 (de) * 1998-05-14 1999-11-17 Schering Aktiengesellschaft Ungesättigte Cholestan-derivate zur Regulierung von Meiose und pharmazeutische Präparate davon
KR20010043558A (ko) * 1998-05-13 2001-05-25 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 감수분열 조절 화합물
AU4498299A (en) * 1998-06-19 2000-01-10 Novo Nordisk A/S Meiosis regulating compounds
US6528501B1 (en) 1998-12-11 2003-03-04 Akzo Nobel N.V. 22s-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity
WO2000036132A1 (en) * 1998-12-14 2000-06-22 Merck & Co., Inc. Hiv integrase inhibitors
KR20010101820A (ko) * 1999-02-10 2001-11-14 에바-마리아 시마-메이어, 얼설라 멜져, 마거, 하르트만 불포화 콜레스탄 유도체 및 감수분열 조절 약제 제조에있어서 그의 용도
AU2794100A (en) 1999-02-24 2000-09-14 Novo Nordisk A/S Treatment of infertility
EP1156821B1 (de) 1999-02-24 2007-05-02 Novo Nordisk A/S Behandlung von unfruchtbarkeit
JP2003509365A (ja) 1999-09-16 2003-03-11 ノボ ノルディスク アクティーゼルスカブ Ｉｖｆ用の組成物
EP1127890A1 (de) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose
AU2001240624A1 (en) * 2000-02-25 2001-09-03 Novo-Nordisk A/S Improvement of implantation rate
EP1245572A1 (de) 2001-03-26 2002-10-02 Schering Aktiengesellschaft Aminosterol-Verbindungen, ihre Verwendung zur Herstellung Meiose-regulierender Medikamenten und ein Vefahren zu ihrer Herstellung
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
US8399441B2 (en) 2004-10-25 2013-03-19 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
CN102258004B (zh) * 2010-05-27 2013-07-17 中国科学院动物研究所 一种体外保存/培养卵母细胞以抑制卵母细胞生发泡破裂的方法
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
HUE062616T2 (hu) 2011-09-08 2023-11-28 Sage Therapeutics Inc Neuroaktív szteroidok, készítmények és alkalmazásaik
FI3932932T3 (fi) 2013-03-13 2025-10-15 Sage Therapeutics Inc Neuroaktiivisia steroideja ja niiden käyttömenetelmiä
EA201990684A1 (ru) 2013-12-24 2020-12-30 Вирджиния Коммонвелт Юниверсити Способы применения оксигенированных холестеролсульфатов (ocs)
JP6628745B2 (ja) 2014-06-18 2020-01-15 セージ セラピューティクス， インコーポレイテッド オキシステロールおよびその使用方法
EA024619B1 (ru) * 2014-11-21 2016-10-31 Эльвин Гаджи оглы Керимли ФРАКСИНОСТЕРИН - 24β-ЭТИЛХОЛЕСТА-20-КАРБОКСИ-6(7),8(9)-ДИЕН 3β-ОЛА И ЕГО ПРОИЗВОДНОЕ
WO2017007832A1 (en) 2015-07-06 2017-01-12 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
PT3319611T (pt) 2015-07-06 2021-04-22 Sage Therapeutics Inc Oxisteróis e métodos de utilização dos mesmos
DK3812392T3 (da) 2015-07-06 2025-07-21 Sage Therapeutics Inc Oxysteroler og fremgangsmåder til anvendelse deraf
ES2921010T3 (es) 2016-04-01 2022-08-16 Sage Therapeutics Inc Oxisteroles y procedimientos de uso de los mismos
WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
WO2018009867A1 (en) 2016-07-07 2018-01-11 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
IL298681A (en) 2016-08-02 2023-01-01 Univ Virginia Commonwealth Preparations
MA46351A (fr) 2016-09-30 2021-06-02 Sage Therapeutics Inc Oxystérols substitués en c7 et procédés en tant que modulateurs nmda
DK3529257T3 (da) 2016-10-18 2023-08-07 Sage Therapeutics Inc Oxysteroler og fremgangsmåder til anvendelse deraf
KR102521573B1 (ko) 2016-10-18 2023-04-14 세이지 테라퓨틱스, 인크. 옥시스테롤 및 그의 사용 방법
CN112430251A (zh) * 2020-11-23 2021-03-02 广州瀚信通信科技股份有限公司 一种治疗白内障的化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols

Also Published As

Publication number Publication date
DE69630802T2 (de) 2004-08-12
BR9608968A (pt) 1999-06-29
NO976044D0 (no) 1997-12-22
RU2182909C2 (ru) 2002-05-27
CA2224866A1 (en) 1997-01-09
AU718246B2 (en) 2000-04-13
ATE254628T1 (de) 2003-12-15
PL185622B1 (pl) 2003-06-30
AU6122796A (en) 1997-01-22
HUP9900454A3 (en) 1999-11-29
HUP9900454A2 (hu) 1999-06-28
CZ408097A3 (cs) 1998-06-17
KR19990028366A (ko) 1999-04-15
CN1191543A (zh) 1998-08-26
PL324219A1 (en) 1998-05-11
WO1997000884A1 (en) 1997-01-09
AR003441A1 (es) 1998-08-05
NO314231B1 (no) 2003-02-17
EP0857173A1 (de) 1998-08-12
JPH11507929A (ja) 1999-07-13
DE69630802D1 (de) 2003-12-24
NO976044L (no) 1998-02-20
MX9800123A (es) 1998-03-29
TW474943B (en) 2002-02-01
EP0857173B1 (de) 2003-11-19

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