IL131755A0 - Crystalline amine salt of cefdinir - Google Patents

Crystalline amine salt of cefdinir

Info

Publication number
IL131755A0
IL131755A0 IL13175598A IL13175598A IL131755A0 IL 131755 A0 IL131755 A0 IL 131755A0 IL 13175598 A IL13175598 A IL 13175598A IL 13175598 A IL13175598 A IL 13175598A IL 131755 A0 IL131755 A0 IL 131755A0
Authority
IL
Israel
Prior art keywords
cefdinir
amine salt
crystalline amine
crystalline
salt
Prior art date
Application number
IL13175598A
Other languages
English (en)
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of IL131755A0 publication Critical patent/IL131755A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13175598A 1997-04-04 1998-04-02 Crystalline amine salt of cefdinir IL131755A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0057097A AT405283B (de) 1997-04-04 1997-04-04 Neues kristallines 7-(z)-(2-(2-aminothiazol-4-yl) -2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4- carbonsäure dicyclohexylammoniumsalz und verfahren zu dessen herstellung
PCT/EP1998/001953 WO1998045299A1 (fr) 1997-04-04 1998-04-02 Sel amine cristallin de cefdinir

Publications (1)

Publication Number Publication Date
IL131755A0 true IL131755A0 (en) 2001-03-19

Family

ID=3494111

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13175598A IL131755A0 (en) 1997-04-04 1998-04-02 Crystalline amine salt of cefdinir

Country Status (18)

Country Link
US (1) US6350869B1 (fr)
EP (1) EP0973779B1 (fr)
JP (1) JP3421354B2 (fr)
KR (1) KR100442717B1 (fr)
CN (1) CN1139596C (fr)
AT (2) AT405283B (fr)
AU (1) AU731413B2 (fr)
BR (1) BR9809745A (fr)
CA (1) CA2283718A1 (fr)
DE (1) DE69816056T2 (fr)
HU (1) HUP0002987A3 (fr)
ID (1) ID22536A (fr)
IL (1) IL131755A0 (fr)
NO (1) NO994466L (fr)
PL (1) PL335620A1 (fr)
SK (1) SK134399A3 (fr)
TR (1) TR199902406T2 (fr)
WO (1) WO1998045299A1 (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080113025A1 (en) * 1998-11-02 2008-05-15 Elan Pharma International Limited Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
KR100451672B1 (ko) * 2001-06-05 2004-10-08 한미약품 주식회사 결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법
ITMI20020913A0 (it) * 2002-04-29 2002-04-29 Acs Dobfar Spa Nuova forma cristallina del cefdinir
EP1842852A1 (fr) 2002-08-13 2007-10-10 Sandoz AG Un intermediaire de cefdinir
ITMI20022076A1 (it) * 2002-10-01 2004-04-02 Antibioticos Spa Sali di intermedi del cefdinir.
WO2004046154A1 (fr) * 2002-11-15 2004-06-03 Orchid Chemicals & Pharmaceuticals Ltd Nouvel hydrate amorphe d'une cephalosporine
ITMI20022724A1 (it) * 2002-12-20 2004-06-21 Antibioticos Spa Sali cristallini del cefdinir.
US20070106073A1 (en) * 2003-03-24 2007-05-10 Eiji Imai Novel crystal of 7-[2-[(2-aminothiazol-4-yl)-2-hydroxyiminoacetamide-3-vinyl-3-cephem-4-carboxylic acid (syn isomer) and method for preparation thereof
WO2004104010A1 (fr) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Forme cristalline de cefdinir
US20040242556A1 (en) * 2003-06-02 2004-12-02 Ramesh Dandala Novel crystalline form of cefdinir
US20050137182A1 (en) * 2003-06-02 2005-06-23 Ramesh Dandala Novel crystalline form of cefdinir
US20050059818A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Polymorph of a pharmaceutical
US20050059819A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Cefdinir pyridine salt
US20050113355A1 (en) * 2003-09-12 2005-05-26 Duerst Richard W. Cefdinir pyridine salt
US20060142261A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060211676A1 (en) * 2004-03-16 2006-09-21 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20050209211A1 (en) * 2004-03-16 2005-09-22 Devalina Law Trihemihydrate, anhydrate and novel hydrate forms of Cefdinir
US20060142563A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
WO2005090360A1 (fr) * 2004-03-19 2005-09-29 Orchid Chemicals & Pharmaceuticals Limited Nouveau polymorphe de cefdinir
US20060069079A1 (en) * 2004-09-27 2006-03-30 Sever Nancy E Stable amorphous cefdinir
US20050245738A1 (en) * 2004-05-03 2005-11-03 Lupin Ltd Stable bioavailable crystalline form or cefdinir and a process for the preparation thereof
WO2006010978A1 (fr) * 2004-06-30 2006-02-02 Wockhardt Limited Formes polymorphes de cefdinir, et son sel d'imidazole
CN101031574A (zh) 2004-07-05 2007-09-05 幽兰化学医药有限公司 头孢菌素类抗生素的新二胺盐及其制备
WO2006018807A1 (fr) * 2004-08-16 2006-02-23 Ranbaxy Laboratories Limited Formes cristallines de cefdinir
ITMI20042231A1 (it) * 2004-11-19 2005-02-19 Antibioticos Spa Cefdinir sale d'ammonio in forma cristallina
MX2007006018A (es) * 2004-11-30 2007-06-07 Astellas Pharma Inc Suspension farmaceutica oral novedosa de cristal de cefdinir.
GB2421024A (en) * 2004-12-07 2006-06-14 Sandoz Ag Cefdinir crystalline form C
WO2006117794A1 (fr) * 2005-05-02 2006-11-09 Hetero Drugs Limited Nouvelle forme cristalline de cefdinir
US20080287673A1 (en) * 2005-06-15 2008-11-20 Parthasaradhi Reddy Bandk Cefdinir process
CN1903860B (zh) * 2005-07-25 2012-01-18 四川抗菌素工业研究所有限公司 溶媒法制备高纯度头孢他美钠工艺及医药用途
WO2007053722A2 (fr) * 2005-10-31 2007-05-10 Teva Pharmaceutical Industries Ltd. Formes cristalline du sel de cesium de cefdinir
US20070128268A1 (en) * 2005-12-07 2007-06-07 Herwig Jennewein Pharmaceutical compositions comprising an antibiotic
CN101481383B (zh) * 2008-12-31 2012-01-11 杭州奥默医药技术有限公司 头孢地尼酸式复盐化合物及制备方法
US8614315B2 (en) 2009-12-25 2013-12-24 Mahmut Bilgic Cefdinir and cefixime formulations and uses thereof
TR200909784A1 (tr) * 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Yeni sefdinir tuzları
CN101974020B (zh) * 2010-11-19 2012-09-12 苏州中联化学制药有限公司 一种头孢地尼的合成方法
CN102010427B (zh) * 2010-11-19 2012-09-12 苏州中联化学制药有限公司 一种头孢地尼的制备方法
CN103012433B (zh) * 2012-12-13 2015-06-24 珠海保税区丽珠合成制药有限公司 头孢地尼晶型b的制备方法
CN108546270B (zh) * 2017-05-31 2019-11-08 郑州大学第一附属医院 制备头孢地尼的方法
CN107286148B (zh) * 2017-06-20 2019-10-15 广州市桐晖通医药科技有限公司 一种头孢地尼的制备方法及其新的中间体化合物
CN111635419B (zh) * 2020-07-13 2022-05-24 广药白云山化学制药(珠海)有限公司 一种头孢地尼精制母液的处理方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5564M (fr) 1964-03-14 1968-01-02
GB8323034D0 (en) * 1983-08-26 1983-09-28 Fujisawo Pharmaceutical Co Ltd 7-substituted-3-vinyl-3-cephem compounds
ZA885709B (en) 1987-08-19 1989-04-26 Fujisawa Pharmaceutical Co Novel crystalline 7-(2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid(syn isomer)
ATE205214T1 (de) * 1992-02-05 2001-09-15 Biochemie Gmbh Verfahren zur reinigung eines 3-cephem-4-carboxyl säure derivates
CN1130908A (zh) * 1994-07-22 1996-09-11 安蒂比奥蒂科斯公司 戊二酸单酰基7-氨基头孢烷酸衍生物及其制备方法
AT403049B (de) 1995-08-14 1997-10-27 Biochemie Gmbh Abreicherung von 7-adca in 3-vinyl-aca
US6093814A (en) 1995-12-27 2000-07-25 Hanmi Pharmaceutical Co., Ltd. Process for preparation of cefdinir
AT404251B (de) * 1996-08-14 1998-10-27 Biochemie Gmbh Neues kristallines salz von cefixim

Also Published As

Publication number Publication date
KR20010005907A (ko) 2001-01-15
CN1251590A (zh) 2000-04-26
TR199902406T2 (xx) 2000-02-21
SK134399A3 (en) 2000-05-16
BR9809745A (pt) 2000-06-20
DE69816056T2 (de) 2004-04-15
AU731413B2 (en) 2001-03-29
WO1998045299A1 (fr) 1998-10-15
EP0973779A1 (fr) 2000-01-26
US6350869B1 (en) 2002-02-26
EP0973779B1 (fr) 2003-07-02
NO994466D0 (no) 1999-09-15
DE69816056D1 (de) 2003-08-07
KR100442717B1 (ko) 2004-08-02
ID22536A (id) 1999-11-04
AT405283B (de) 1999-06-25
NO994466L (no) 1999-09-15
CA2283718A1 (fr) 1998-10-15
AU7428898A (en) 1998-10-30
JP2000514833A (ja) 2000-11-07
HUP0002987A2 (hu) 2001-02-28
ATA57097A (de) 1998-11-15
JP3421354B2 (ja) 2003-06-30
CN1139596C (zh) 2004-02-25
PL335620A1 (en) 2000-05-08
ATE244249T1 (de) 2003-07-15
HUP0002987A3 (en) 2001-04-28

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